Gene Page: SFT2D1
Summary ?
| GeneID | 113402 |
| Symbol | SFT2D1 |
| Synonyms | C6orf83|pRGR1 |
| Description | SFT2 domain containing 1 |
| Reference | HGNC:HGNC:21102|Ensembl:ENSG00000198818|HPRD:12903|Vega:OTTHUMG00000016001 |
| Gene type | protein-coding |
| Map location | 6q27 |
| Pascal p-value | 0.19 |
| Sherlock p-value | 0.001 |
| Fetal beta | -0.513 |
| eGene | Anterior cingulate cortex BA24 Myers' cis & trans |
Gene in Data Sources
| Gene set name | Method of gene set | Description | Info |
|---|---|---|---|
| CV:PGCnp | Genome-wide Association Study | GWAS |
Section I. Genetics and epigenetics annotation
eQTL annotation
| SNP ID | Chromosome | Position | eGene | Gene Entrez ID | pvalue | qvalue | TSS distance | eQTL type |
|---|---|---|---|---|---|---|---|---|
| rs2403775 | chr8 | 133472361 | SFT2D1 | 113402 | 0.18 | trans | ||
| rs13201817 | 6 | 166352404 | SFT2D1 | ENSG00000198818.5 | 7.09945E-7 | 0.02 | 403675 | gtex_brain_ba24 |
| rs67996003 | 6 | 166353943 | SFT2D1 | ENSG00000198818.5 | 7.09945E-7 | 0.02 | 402136 | gtex_brain_ba24 |
| rs35886707 | 6 | 166358774 | SFT2D1 | ENSG00000198818.5 | 7.09945E-7 | 0.02 | 397305 | gtex_brain_ba24 |
| rs13210201 | 6 | 166363681 | SFT2D1 | ENSG00000198818.5 | 1.16315E-6 | 0.02 | 392398 | gtex_brain_ba24 |
| rs7751441 | 6 | 166366573 | SFT2D1 | ENSG00000198818.5 | 4.42127E-7 | 0.02 | 389506 | gtex_brain_ba24 |
| rs56810654 | 6 | 166366788 | SFT2D1 | ENSG00000198818.5 | 7.32535E-7 | 0.02 | 389291 | gtex_brain_ba24 |
| rs59467904 | 6 | 166366821 | SFT2D1 | ENSG00000198818.5 | 7.80366E-7 | 0.02 | 389258 | gtex_brain_ba24 |
Section II. Transcriptome annotation
General gene expression (GTEx)
Gene expression during devlopment (BrainCloud)
Footnote:
A total of 269 time points ploted, with n=38 fetal samples (x=1:38). Each triangle represents one time point.
Gene expression of temporal and spatial changes (BrainSpan)
Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes the lower 25% and upper 25% of the expression distribution.
No co-expressed genes in brain regions
Section III. Gene Ontology annotation
| Biological process | GO term | Evidence | Neuro keywords | PubMed ID |
|---|---|---|---|---|
| GO:0015031 | protein transport | IEA | - | |
| Cellular component | GO term | Evidence | Neuro keywords | PubMed ID |
| GO:0016020 | membrane | IEA | - | |
| GO:0016021 | integral to membrane | IEA | - |
Section V. Pathway annotation
| Pathway name | Pathway size | # SZGR 2.0 genes in pathway | Info |
|---|---|---|---|
| WANG LMO4 TARGETS UP | 372 | 227 | All SZGR 2.0 genes in this pathway |
| WEI MIR34A TARGETS | 148 | 97 | All SZGR 2.0 genes in this pathway |
| PARK HSC VS MULTIPOTENT PROGENITORS DN | 18 | 12 | All SZGR 2.0 genes in this pathway |
| LEE LIVER CANCER SURVIVAL DN | 175 | 103 | All SZGR 2.0 genes in this pathway |
| RATTENBACHER BOUND BY CELF1 | 467 | 251 | All SZGR 2.0 genes in this pathway |