Summary ?
Descriptioncopine 4
Gene typeprotein-coding
Map location3q22.1
Pascal p-value0.019
Sherlock p-value0.97
Fetal beta-2.183
DMG1 (# studies)
eGeneMyers' cis & trans

Gene in Data Sources
Gene set name Method of gene setDescriptionInfo
CV:GWASdbGenome-wide Association StudiesGWASdb records for schizophrenia
CV:PGCnpGenome-wide Association StudyGWAS
DMG:Wockner_2014Genome-wide DNA methylation analysisThis dataset includes 4641 differentially methylated probes corresponding to 2929 unique genes between schizophrenia patients (n=24) and controls (n=24). 1

Section I. Genetics and epigenetics annotation

@Differentially methylated gene

ProbeChromosomePositionNearest geneP (dis)Beta (dis)FDR (dis)Study

@eQTL annotation

SNP IDChromosomePositioneGeneGene Entrez IDpvalueqvalueTSS distanceeQTL type

Section II. Transcriptome annotation

General gene expression (GTEx)

Not available

Gene expression during devlopment (BrainCloud)

A total of 269 time points ploted, with n=38 fetal samples (x=1:38). Each triangle represents one time point.

Gene expression of temporal and spatial changes (BrainSpan)

SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes the lower 25% and upper 25% of the expression distribution.

No co-expressed genes in brain regions

Section IV. Protein-protein interaction annotation

InteractorsAliases BOfficial full name BExperimentalSourcePubMed ID
ACTBPS1TP5BP1actin, beta-HPRD12522145 
BCORANOP2 | FLJ20285 | FLJ38041 | KIAA1575 | MAA2 | MCOPS2 | MGC131961 | MGC71031BCL6 co-repressor-HPRD12522145 
CCDC22CXorf37 | JM1coiled-coil domain containing 22-HPRD12522145 
CPNE1COPN1 | CPN1 | MGC1142copine I-HPRD12522145 
MAP2K1MAPKK1 | MEK1 | MKK1 | PRKMK1mitogen-activated protein kinase kinase 1-HPRD12522145 
MYCBPAMY-1c-myc binding protein-HPRD12522145 
PDCD6ALG-2 | FLJ46208 | MGC111017 | MGC119050 | MGC9123 | PEF1Bprogrammed cell death 6-HPRD12522145 
PITPNM2KIAA1457 | NIR3 | RDGB2 | RDGBA2phosphatidylinositol transfer protein, membrane-associated 2-HPRD12522145 
PPP5CFLJ36922 | PP5 | PPP5protein phosphatase 5, catalytic subunit-HPRD12522145 
SKILSNO | SnoA | SnoNSKI-like oncogene-HPRD12522145 
SPTBN1ELF | SPTB2 | betaSpIIspectrin, beta, non-erythrocytic 1-HPRD12522145 
UBE2MUBC-RS2 | UBC12 | hUbc12ubiquitin-conjugating enzyme E2M (UBC12 homolog, yeast)-HPRD12522145 

Section V. Pathway annotation

Pathway namePathway size# SZGR 2.0 genes in pathwayInfo
THUM SYSTOLIC HEART FAILURE DN 244147All SZGR 2.0 genes in this pathway
GOZGIT ESR1 TARGETS DN 781465All SZGR 2.0 genes in this pathway
FUJII YBX1 TARGETS UP 4328All SZGR 2.0 genes in this pathway