Gene Page: COL26A1
Summary ?
| GeneID | 136227 |
| Symbol | COL26A1 |
| Synonyms | EMI6|EMID2|EMU2|SH2B |
| Description | collagen type XXVI alpha 1 |
| Reference | MIM:608927|HGNC:HGNC:18038|Ensembl:ENSG00000160963|HPRD:16405|Vega:OTTHUMG00000150033 |
| Gene type | protein-coding |
| Map location | 7q22.1 |
| Pascal p-value | 0.023 |
| eGene | Caudate basal ganglia Cerebellar Hemisphere Cerebellum Hypothalamus Nucleus accumbens basal ganglia Putamen basal ganglia |
Gene in Data Sources
| Gene set name | Method of gene set | Description | Info |
|---|---|---|---|
| CV:PGCnp | Genome-wide Association Study | GWAS |
Section I. Genetics and epigenetics annotation
eQTL annotation
| SNP ID | Chromosome | Position | eGene | Gene Entrez ID | pvalue | qvalue | TSS distance | eQTL type |
|---|---|---|---|---|---|---|---|---|
| rs56045466 | 7 | 100989670 | COL26A1 | ENSG00000160963.9 | 3.454E-7 | 0.01 | -16431 | gtex_brain_putamen_basal |
| rs13242704 | 7 | 100991402 | COL26A1 | ENSG00000160963.9 | 4.545E-7 | 0.01 | -14699 | gtex_brain_putamen_basal |
| rs4568540 | 7 | 100992737 | COL26A1 | ENSG00000160963.9 | 3.984E-7 | 0.01 | -13364 | gtex_brain_putamen_basal |
| rs66703493 | 7 | 100993063 | COL26A1 | ENSG00000160963.9 | 4.017E-6 | 0.01 | -13038 | gtex_brain_putamen_basal |
| rs13226233 | 7 | 100993655 | COL26A1 | ENSG00000160963.9 | 2.702E-6 | 0.01 | -12446 | gtex_brain_putamen_basal |
| rs13226176 | 7 | 100993838 | COL26A1 | ENSG00000160963.9 | 2.817E-7 | 0.01 | -12263 | gtex_brain_putamen_basal |
| rs55941500 | 7 | 100993894 | COL26A1 | ENSG00000160963.9 | 4.017E-6 | 0.01 | -12207 | gtex_brain_putamen_basal |
| rs7805075 | 7 | 100994271 | COL26A1 | ENSG00000160963.9 | 4.017E-6 | 0.01 | -11830 | gtex_brain_putamen_basal |
| rs59412968 | 7 | 100997645 | COL26A1 | ENSG00000160963.9 | 2.192E-7 | 0.01 | -8456 | gtex_brain_putamen_basal |
| rs58252552 | 7 | 100997776 | COL26A1 | ENSG00000160963.9 | 2.324E-7 | 0.01 | -8325 | gtex_brain_putamen_basal |
| rs6965312 | 7 | 100997844 | COL26A1 | ENSG00000160963.9 | 3.213E-7 | 0.01 | -8257 | gtex_brain_putamen_basal |
| rs6965654 | 7 | 100998119 | COL26A1 | ENSG00000160963.9 | 2.447E-7 | 0.01 | -7982 | gtex_brain_putamen_basal |
| rs6965814 | 7 | 100998263 | COL26A1 | ENSG00000160963.9 | 2.303E-7 | 0.01 | -7838 | gtex_brain_putamen_basal |
| rs10254581 | 7 | 100998462 | COL26A1 | ENSG00000160963.9 | 2.295E-7 | 0.01 | -7639 | gtex_brain_putamen_basal |
| rs7782256 | 7 | 100998618 | COL26A1 | ENSG00000160963.9 | 2.299E-7 | 0.01 | -7483 | gtex_brain_putamen_basal |
| rs12673177 | 7 | 100998895 | COL26A1 | ENSG00000160963.9 | 2.303E-7 | 0.01 | -7206 | gtex_brain_putamen_basal |
| rs6976146 | 7 | 100999739 | COL26A1 | ENSG00000160963.9 | 2.289E-7 | 0.01 | -6362 | gtex_brain_putamen_basal |
| rs4257954 | 7 | 101000095 | COL26A1 | ENSG00000160963.9 | 2.294E-7 | 0.01 | -6006 | gtex_brain_putamen_basal |
| rs6943255 | 7 | 101000802 | COL26A1 | ENSG00000160963.9 | 2.283E-7 | 0.01 | -5299 | gtex_brain_putamen_basal |
| rs56206210 | 7 | 101000838 | COL26A1 | ENSG00000160963.9 | 3.026E-7 | 0.01 | -5263 | gtex_brain_putamen_basal |
| rs6943474 | 7 | 101001016 | COL26A1 | ENSG00000160963.9 | 2.282E-7 | 0.01 | -5085 | gtex_brain_putamen_basal |
| rs55815848 | 7 | 101001029 | COL26A1 | ENSG00000160963.9 | 2.282E-7 | 0.01 | -5072 | gtex_brain_putamen_basal |
| rs9768555 | 7 | 101003926 | COL26A1 | ENSG00000160963.9 | 6.363E-7 | 0.01 | -2175 | gtex_brain_putamen_basal |
| rs9771281 | 7 | 101003942 | COL26A1 | ENSG00000160963.9 | 6.184E-7 | 0.01 | -2159 | gtex_brain_putamen_basal |
| rs9768559 | 7 | 101003943 | COL26A1 | ENSG00000160963.9 | 5.929E-7 | 0.01 | -2158 | gtex_brain_putamen_basal |
| rs7793499 | 7 | 101004484 | COL26A1 | ENSG00000160963.9 | 2.597E-6 | 0.01 | -1617 | gtex_brain_putamen_basal |
| rs7794015 | 7 | 101004539 | COL26A1 | ENSG00000160963.9 | 2.593E-6 | 0.01 | -1562 | gtex_brain_putamen_basal |
| rs7776842 | 7 | 101004570 | COL26A1 | ENSG00000160963.9 | 2.59E-6 | 0.01 | -1531 | gtex_brain_putamen_basal |
| rs60312189 | 7 | 101004810 | COL26A1 | ENSG00000160963.9 | 2.606E-6 | 0.01 | -1291 | gtex_brain_putamen_basal |
| rs66510359 | 7 | 101005097 | COL26A1 | ENSG00000160963.9 | 2.635E-6 | 0.01 | -1004 | gtex_brain_putamen_basal |
| rs35761702 | 7 | 101005192 | COL26A1 | ENSG00000160963.9 | 2.586E-6 | 0.01 | -909 | gtex_brain_putamen_basal |
| rs36038216 | 7 | 101005226 | COL26A1 | ENSG00000160963.9 | 2.59E-6 | 0.01 | -875 | gtex_brain_putamen_basal |
| rs66606106 | 7 | 101005242 | COL26A1 | ENSG00000160963.9 | 2.59E-6 | 0.01 | -859 | gtex_brain_putamen_basal |
| rs66656437 | 7 | 101005257 | COL26A1 | ENSG00000160963.9 | 2.59E-6 | 0.01 | -844 | gtex_brain_putamen_basal |
| rs35571793 | 7 | 101005357 | COL26A1 | ENSG00000160963.9 | 2.517E-6 | 0.01 | -744 | gtex_brain_putamen_basal |
| rs10228118 | 7 | 101005735 | COL26A1 | ENSG00000160963.9 | 2.315E-7 | 0.01 | -366 | gtex_brain_putamen_basal |
| rs10228469 | 7 | 101005926 | COL26A1 | ENSG00000160963.9 | 2.285E-7 | 0.01 | -175 | gtex_brain_putamen_basal |
| rs4989272 | 7 | 101006193 | COL26A1 | ENSG00000160963.9 | 2.147E-7 | 0.01 | 92 | gtex_brain_putamen_basal |
| rs4989271 | 7 | 101006216 | COL26A1 | ENSG00000160963.9 | 1.673E-7 | 0.01 | 115 | gtex_brain_putamen_basal |
| rs4989270 | 7 | 101006223 | COL26A1 | ENSG00000160963.9 | 3.981E-7 | 0.01 | 122 | gtex_brain_putamen_basal |
| rs4989269 | 7 | 101006230 | COL26A1 | ENSG00000160963.9 | 2.279E-7 | 0.01 | 129 | gtex_brain_putamen_basal |
| rs4989268 | 7 | 101006233 | COL26A1 | ENSG00000160963.9 | 2.591E-7 | 0.01 | 132 | gtex_brain_putamen_basal |
| rs4989267 | 7 | 101006376 | COL26A1 | ENSG00000160963.9 | 2.279E-7 | 0.01 | 275 | gtex_brain_putamen_basal |
| rs4989266 | 7 | 101006382 | COL26A1 | ENSG00000160963.9 | 2.279E-7 | 0.01 | 281 | gtex_brain_putamen_basal |
| rs4989265 | 7 | 101006488 | COL26A1 | ENSG00000160963.9 | 9.252E-8 | 0.01 | 387 | gtex_brain_putamen_basal |
| rs62639087 | 7 | 101006739 | COL26A1 | ENSG00000160963.9 | 6.766E-7 | 0.01 | 638 | gtex_brain_putamen_basal |
| rs71559408 | 7 | 101006830 | COL26A1 | ENSG00000160963.9 | 4.841E-7 | 0.01 | 729 | gtex_brain_putamen_basal |
| rs71559410 | 7 | 101006865 | COL26A1 | ENSG00000160963.9 | 9.514E-7 | 0.01 | 764 | gtex_brain_putamen_basal |
| rs10248094 | 7 | 101006911 | COL26A1 | ENSG00000160963.9 | 3.047E-7 | 0.01 | 810 | gtex_brain_putamen_basal |
| rs10261809 | 7 | 101007030 | COL26A1 | ENSG00000160963.9 | 2.58E-7 | 0.01 | 929 | gtex_brain_putamen_basal |
| rs10232921 | 7 | 101007192 | COL26A1 | ENSG00000160963.9 | 2.566E-7 | 0.01 | 1091 | gtex_brain_putamen_basal |
| rs6465798 | 7 | 101007460 | COL26A1 | ENSG00000160963.9 | 2.282E-7 | 0.01 | 1359 | gtex_brain_putamen_basal |
| rs398047904 | 7 | 101007525 | COL26A1 | ENSG00000160963.9 | 2.28E-7 | 0.01 | 1424 | gtex_brain_putamen_basal |
| rs6465799 | 7 | 101007557 | COL26A1 | ENSG00000160963.9 | 2.28E-7 | 0.01 | 1456 | gtex_brain_putamen_basal |
| rs4729693 | 7 | 101007777 | COL26A1 | ENSG00000160963.9 | 2.36E-7 | 0.01 | 1676 | gtex_brain_putamen_basal |
| rs4727487 | 7 | 101007816 | COL26A1 | ENSG00000160963.9 | 2.36E-7 | 0.01 | 1715 | gtex_brain_putamen_basal |
| rs535851454 | 7 | 101007847 | COL26A1 | ENSG00000160963.9 | 5.482E-7 | 0.01 | 1746 | gtex_brain_putamen_basal |
| rs4729694 | 7 | 101007888 | COL26A1 | ENSG00000160963.9 | 2.282E-7 | 0.01 | 1787 | gtex_brain_putamen_basal |
| rs4729695 | 7 | 101007998 | COL26A1 | ENSG00000160963.9 | 2.282E-7 | 0.01 | 1897 | gtex_brain_putamen_basal |
| rs4478499 | 7 | 101008146 | COL26A1 | ENSG00000160963.9 | 3.027E-7 | 0.01 | 2045 | gtex_brain_putamen_basal |
| rs950515 | 7 | 101008207 | COL26A1 | ENSG00000160963.9 | 2.282E-7 | 0.01 | 2106 | gtex_brain_putamen_basal |
| rs950514 | 7 | 101008320 | COL26A1 | ENSG00000160963.9 | 2.282E-7 | 0.01 | 2219 | gtex_brain_putamen_basal |
| rs2410823 | 7 | 101008534 | COL26A1 | ENSG00000160963.9 | 2.282E-7 | 0.01 | 2433 | gtex_brain_putamen_basal |
| rs950513 | 7 | 101008538 | COL26A1 | ENSG00000160963.9 | 3.71E-7 | 0.01 | 2437 | gtex_brain_putamen_basal |
| rs34825981 | 7 | 101008801 | COL26A1 | ENSG00000160963.9 | 4.665E-7 | 0.01 | 2700 | gtex_brain_putamen_basal |
| rs13243027 | 7 | 101008812 | COL26A1 | ENSG00000160963.9 | 2.749E-7 | 0.01 | 2711 | gtex_brain_putamen_basal |
| rs13243416 | 7 | 101008870 | COL26A1 | ENSG00000160963.9 | 2.282E-7 | 0.01 | 2769 | gtex_brain_putamen_basal |
| rs12673743 | 7 | 101008965 | COL26A1 | ENSG00000160963.9 | 3.255E-7 | 0.01 | 2864 | gtex_brain_putamen_basal |
| rs10953334 | 7 | 101008978 | COL26A1 | ENSG00000160963.9 | 3.282E-7 | 0.01 | 2877 | gtex_brain_putamen_basal |
| rs10953336 | 7 | 101009223 | COL26A1 | ENSG00000160963.9 | 3.027E-7 | 0.01 | 3122 | gtex_brain_putamen_basal |
| rs10953337 | 7 | 101009373 | COL26A1 | ENSG00000160963.9 | 2.282E-7 | 0.01 | 3272 | gtex_brain_putamen_basal |
| rs6958770 | 7 | 101009419 | COL26A1 | ENSG00000160963.9 | 2.282E-7 | 0.01 | 3318 | gtex_brain_putamen_basal |
| rs6945102 | 7 | 101009671 | COL26A1 | ENSG00000160963.9 | 1.54E-6 | 0.01 | 3570 | gtex_brain_putamen_basal |
| rs6963365 | 7 | 101009715 | COL26A1 | ENSG00000160963.9 | 3.71E-7 | 0.01 | 3614 | gtex_brain_putamen_basal |
| rs2410824 | 7 | 101009948 | COL26A1 | ENSG00000160963.9 | 1.739E-6 | 0.01 | 3847 | gtex_brain_putamen_basal |
| rs1010354 | 7 | 101010273 | COL26A1 | ENSG00000160963.9 | 2.282E-7 | 0.01 | 4172 | gtex_brain_putamen_basal |
| rs1010353 | 7 | 101010297 | COL26A1 | ENSG00000160963.9 | 2.282E-7 | 0.01 | 4196 | gtex_brain_putamen_basal |
| rs10227033 | 7 | 101010640 | COL26A1 | ENSG00000160963.9 | 1.539E-6 | 0.01 | 4539 | gtex_brain_putamen_basal |
| rs60044128 | 7 | 101010821 | COL26A1 | ENSG00000160963.9 | 1.718E-6 | 0.01 | 4720 | gtex_brain_putamen_basal |
| rs10953338 | 7 | 101010870 | COL26A1 | ENSG00000160963.9 | 2.282E-7 | 0.01 | 4769 | gtex_brain_putamen_basal |
| rs12666374 | 7 | 101010877 | COL26A1 | ENSG00000160963.9 | 2.282E-7 | 0.01 | 4776 | gtex_brain_putamen_basal |
| rs12670704 | 7 | 101011094 | COL26A1 | ENSG00000160963.9 | 2.145E-7 | 0.01 | 4993 | gtex_brain_putamen_basal |
| rs4729697 | 7 | 101011154 | COL26A1 | ENSG00000160963.9 | 2.145E-7 | 0.01 | 5053 | gtex_brain_putamen_basal |
| rs4727488 | 7 | 101011197 | COL26A1 | ENSG00000160963.9 | 2.145E-7 | 0.01 | 5096 | gtex_brain_putamen_basal |
| rs34227918 | 7 | 101011267 | COL26A1 | ENSG00000160963.9 | 2.145E-7 | 0.01 | 5166 | gtex_brain_putamen_basal |
| rs4727489 | 7 | 101011532 | COL26A1 | ENSG00000160963.9 | 2.282E-7 | 0.01 | 5431 | gtex_brain_putamen_basal |
| rs4729698 | 7 | 101011570 | COL26A1 | ENSG00000160963.9 | 2.282E-7 | 0.01 | 5469 | gtex_brain_putamen_basal |
| rs4729699 | 7 | 101011580 | COL26A1 | ENSG00000160963.9 | 2.282E-7 | 0.01 | 5479 | gtex_brain_putamen_basal |
| rs4729700 | 7 | 101011665 | COL26A1 | ENSG00000160963.9 | 2.282E-7 | 0.01 | 5564 | gtex_brain_putamen_basal |
| rs4727490 | 7 | 101011723 | COL26A1 | ENSG00000160963.9 | 2.282E-7 | 0.01 | 5622 | gtex_brain_putamen_basal |
| rs6956224 | 7 | 101011824 | COL26A1 | ENSG00000160963.9 | 3.82E-7 | 0.01 | 5723 | gtex_brain_putamen_basal |
| rs4473960 | 7 | 101012046 | COL26A1 | ENSG00000160963.9 | 2.282E-7 | 0.01 | 5945 | gtex_brain_putamen_basal |
| rs4236556 | 7 | 101012117 | COL26A1 | ENSG00000160963.9 | 2.282E-7 | 0.01 | 6016 | gtex_brain_putamen_basal |
| rs4473961 | 7 | 101012354 | COL26A1 | ENSG00000160963.9 | 2.282E-7 | 0.01 | 6253 | gtex_brain_putamen_basal |
| rs6974909 | 7 | 101012370 | COL26A1 | ENSG00000160963.9 | 2.332E-7 | 0.01 | 6269 | gtex_brain_putamen_basal |
| rs13228295 | 7 | 101012467 | COL26A1 | ENSG00000160963.9 | 4.766E-7 | 0.01 | 6366 | gtex_brain_putamen_basal |
| rs13242788 | 7 | 101012588 | COL26A1 | ENSG00000160963.9 | 2.27E-7 | 0.01 | 6487 | gtex_brain_putamen_basal |
| rs10953339 | 7 | 101013188 | COL26A1 | ENSG00000160963.9 | 3.791E-7 | 0.01 | 7087 | gtex_brain_putamen_basal |
| rs10953340 | 7 | 101013221 | COL26A1 | ENSG00000160963.9 | 3.199E-7 | 0.01 | 7120 | gtex_brain_putamen_basal |
| rs6962323 | 7 | 101013297 | COL26A1 | ENSG00000160963.9 | 1.312E-6 | 0.01 | 7196 | gtex_brain_putamen_basal |
| rs201681020 | 7 | 101014245 | COL26A1 | ENSG00000160963.9 | 2.105E-7 | 0.01 | 8144 | gtex_brain_putamen_basal |
| rs13235901 | 7 | 101014362 | COL26A1 | ENSG00000160963.9 | 2.104E-7 | 0.01 | 8261 | gtex_brain_putamen_basal |
| rs72236546 | 7 | 101014880 | COL26A1 | ENSG00000160963.9 | 6.192E-7 | 0.01 | 8779 | gtex_brain_putamen_basal |
| rs12671124 | 7 | 101014928 | COL26A1 | ENSG00000160963.9 | 2.108E-7 | 0.01 | 8827 | gtex_brain_putamen_basal |
| rs12671249 | 7 | 101015507 | COL26A1 | ENSG00000160963.9 | 2.917E-7 | 0.01 | 9406 | gtex_brain_putamen_basal |
| rs62465625 | 7 | 101015718 | COL26A1 | ENSG00000160963.9 | 2.042E-7 | 0.01 | 9617 | gtex_brain_putamen_basal |
| rs11976450 | 7 | 101015973 | COL26A1 | ENSG00000160963.9 | 2.1E-7 | 0.01 | 9872 | gtex_brain_putamen_basal |
| rs17453425 | 7 | 101016498 | COL26A1 | ENSG00000160963.9 | 1.285E-6 | 0.01 | 10397 | gtex_brain_putamen_basal |
| rs35287067 | 7 | 101016587 | COL26A1 | ENSG00000160963.9 | 2.084E-7 | 0.01 | 10486 | gtex_brain_putamen_basal |
| rs397805394 | 7 | 101016807 | COL26A1 | ENSG00000160963.9 | 5.442E-7 | 0.01 | 10706 | gtex_brain_putamen_basal |
| rs13246653 | 7 | 101016854 | COL26A1 | ENSG00000160963.9 | 2.075E-7 | 0.01 | 10753 | gtex_brain_putamen_basal |
| rs2898575 | 7 | 101017370 | COL26A1 | ENSG00000160963.9 | 2.056E-7 | 0.01 | 11269 | gtex_brain_putamen_basal |
| rs7796766 | 7 | 101017465 | COL26A1 | ENSG00000160963.9 | 2.03E-7 | 0.01 | 11364 | gtex_brain_putamen_basal |
| rs6465801 | 7 | 101017966 | COL26A1 | ENSG00000160963.9 | 1.938E-7 | 0.01 | 11865 | gtex_brain_putamen_basal |
| rs6465802 | 7 | 101017977 | COL26A1 | ENSG00000160963.9 | 1.937E-7 | 0.01 | 11876 | gtex_brain_putamen_basal |
| rs6465803 | 7 | 101018018 | COL26A1 | ENSG00000160963.9 | 1.931E-7 | 0.01 | 11917 | gtex_brain_putamen_basal |
| rs6465804 | 7 | 101018084 | COL26A1 | ENSG00000160963.9 | 3.121E-7 | 0.01 | 11983 | gtex_brain_putamen_basal |
| rs6952218 | 7 | 101018190 | COL26A1 | ENSG00000160963.9 | 1.917E-7 | 0.01 | 12089 | gtex_brain_putamen_basal |
| rs13229821 | 7 | 101019039 | COL26A1 | ENSG00000160963.9 | 1.958E-7 | 0.01 | 12938 | gtex_brain_putamen_basal |
| rs12539948 | 7 | 101019224 | COL26A1 | ENSG00000160963.9 | 3.944E-7 | 0.01 | 13123 | gtex_brain_putamen_basal |
| rs12532346 | 7 | 101019253 | COL26A1 | ENSG00000160963.9 | 4.902E-7 | 0.01 | 13152 | gtex_brain_putamen_basal |
| rs13243252 | 7 | 101019522 | COL26A1 | ENSG00000160963.9 | 3.439E-6 | 0.01 | 13421 | gtex_brain_putamen_basal |
| rs34034933 | 7 | 101019567 | COL26A1 | ENSG00000160963.9 | 3.474E-6 | 0.01 | 13466 | gtex_brain_putamen_basal |
Section II. Transcriptome annotation
General gene expression (GTEx)
Gene expression of temporal and spatial changes (BrainSpan)
Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes the lower 25% and upper 25% of the expression distribution.
No co-expressed genes in brain regions
Section V. Pathway annotation
| Pathway name | Pathway size | # SZGR 2.0 genes in pathway | Info |
|---|---|---|---|
| NABA COLLAGENS | 44 | 26 | All SZGR 2.0 genes in this pathway |
| NABA CORE MATRISOME | 275 | 148 | All SZGR 2.0 genes in this pathway |
| NABA MATRISOME | 1028 | 559 | All SZGR 2.0 genes in this pathway |