Gene Page: ROPN1B
Summary ?
| GeneID | 152015 |
| Symbol | ROPN1B |
| Synonyms | - |
| Description | rhophilin associated tail protein 1B |
| Reference | HGNC:HGNC:31927|Ensembl:ENSG00000114547|HPRD:17985|Vega:OTTHUMG00000162651 |
| Gene type | protein-coding |
| Map location | 3q21.2 |
| Pascal p-value | 0.024 |
| eGene | Caudate basal ganglia Cortex Frontal Cortex BA9 Hypothalamus Nucleus accumbens basal ganglia Putamen basal ganglia |
Gene in Data Sources
| Gene set name | Method of gene set | Description | Info |
|---|---|---|---|
| CV:PGCnp | Genome-wide Association Study | GWAS |
Section I. Genetics and epigenetics annotation
eQTL annotation
| SNP ID | Chromosome | Position | eGene | Gene Entrez ID | pvalue | qvalue | TSS distance | eQTL type |
|---|---|---|---|---|---|---|---|---|
| rs11711638 | 3 | 125650752 | ROPN1B | ENSG00000114547.5 | 2.04E-9 | 0 | -37235 | gtex_brain_putamen_basal |
| rs7633797 | 3 | 125653291 | ROPN1B | ENSG00000114547.5 | 6.365E-10 | 0 | -34696 | gtex_brain_putamen_basal |
| rs12490608 | 3 | 125655891 | ROPN1B | ENSG00000114547.5 | 6.741E-10 | 0 | -32096 | gtex_brain_putamen_basal |
| rs139814234 | 3 | 125656720 | ROPN1B | ENSG00000114547.5 | 5.748E-7 | 0 | -31267 | gtex_brain_putamen_basal |
| rs12637341 | 3 | 125661621 | ROPN1B | ENSG00000114547.5 | 6.627E-10 | 0 | -26366 | gtex_brain_putamen_basal |
| rs62270869 | 3 | 125667171 | ROPN1B | ENSG00000114547.5 | 2.102E-7 | 0 | -20816 | gtex_brain_putamen_basal |
| rs10934733 | 3 | 125671342 | ROPN1B | ENSG00000114547.5 | 2.088E-7 | 0 | -16645 | gtex_brain_putamen_basal |
| rs113971852 | 3 | 125671632 | ROPN1B | ENSG00000114547.5 | 3.073E-7 | 0 | -16355 | gtex_brain_putamen_basal |
| rs11919274 | 3 | 125674281 | ROPN1B | ENSG00000114547.5 | 2.297E-9 | 0 | -13706 | gtex_brain_putamen_basal |
| rs4094387 | 3 | 125674989 | ROPN1B | ENSG00000114547.5 | 5.855E-11 | 0 | -12998 | gtex_brain_putamen_basal |
| rs10934735 | 3 | 125675331 | ROPN1B | ENSG00000114547.5 | 1.214E-7 | 0 | -12656 | gtex_brain_putamen_basal |
| rs10934736 | 3 | 125675816 | ROPN1B | ENSG00000114547.5 | 4.166E-7 | 0 | -12171 | gtex_brain_putamen_basal |
| rs11927039 | 3 | 125676162 | ROPN1B | ENSG00000114547.5 | 9.508E-8 | 0 | -11825 | gtex_brain_putamen_basal |
| rs11927019 | 3 | 125676268 | ROPN1B | ENSG00000114547.5 | 5.643E-9 | 0 | -11719 | gtex_brain_putamen_basal |
| rs147523643 | 3 | 125676901 | ROPN1B | ENSG00000114547.5 | 3.741E-7 | 0 | -11086 | gtex_brain_putamen_basal |
| rs4603913 | 3 | 125677009 | ROPN1B | ENSG00000114547.5 | 1.949E-9 | 0 | -10978 | gtex_brain_putamen_basal |
| rs4431055 | 3 | 125677152 | ROPN1B | ENSG00000114547.5 | 9.787E-10 | 0 | -10835 | gtex_brain_putamen_basal |
| rs4613410 | 3 | 125677196 | ROPN1B | ENSG00000114547.5 | 9.534E-10 | 0 | -10791 | gtex_brain_putamen_basal |
| rs201351379 | 3 | 125677218 | ROPN1B | ENSG00000114547.5 | 6.854E-7 | 0 | -10769 | gtex_brain_putamen_basal |
| rs77622614 | 3 | 125677259 | ROPN1B | ENSG00000114547.5 | 7.821E-7 | 0 | -10728 | gtex_brain_putamen_basal |
| rs75605178 | 3 | 125677345 | ROPN1B | ENSG00000114547.5 | 7.294E-10 | 0 | -10642 | gtex_brain_putamen_basal |
| rs62270900 | 3 | 125677618 | ROPN1B | ENSG00000114547.5 | 1.878E-7 | 0 | -10369 | gtex_brain_putamen_basal |
| rs7612436 | 3 | 125677855 | ROPN1B | ENSG00000114547.5 | 5.739E-10 | 0 | -10132 | gtex_brain_putamen_basal |
| rs12108152 | 3 | 125678158 | ROPN1B | ENSG00000114547.5 | 4.011E-7 | 0 | -9829 | gtex_brain_putamen_basal |
| rs67618901 | 3 | 125678215 | ROPN1B | ENSG00000114547.5 | 1.029E-6 | 0 | -9772 | gtex_brain_putamen_basal |
| rs113450106 | 3 | 125678397 | ROPN1B | ENSG00000114547.5 | 1.133E-7 | 0 | -9590 | gtex_brain_putamen_basal |
| rs34579333 | 3 | 125678828 | ROPN1B | ENSG00000114547.5 | 3.171E-11 | 0 | -9159 | gtex_brain_putamen_basal |
| rs34628061 | 3 | 125679063 | ROPN1B | ENSG00000114547.5 | 3.272E-11 | 0 | -8924 | gtex_brain_putamen_basal |
| rs10804572 | 3 | 125680240 | ROPN1B | ENSG00000114547.5 | 3.712E-11 | 0 | -7747 | gtex_brain_putamen_basal |
| rs11920013 | 3 | 125680326 | ROPN1B | ENSG00000114547.5 | 7.52E-8 | 0 | -7661 | gtex_brain_putamen_basal |
| rs11916018 | 3 | 125680373 | ROPN1B | ENSG00000114547.5 | 7.495E-8 | 0 | -7614 | gtex_brain_putamen_basal |
| rs1875686 | 3 | 125680565 | ROPN1B | ENSG00000114547.5 | 3.407E-11 | 0 | -7422 | gtex_brain_putamen_basal |
| rs1847248 | 3 | 125681218 | ROPN1B | ENSG00000114547.5 | 2.853E-11 | 0 | -6769 | gtex_brain_putamen_basal |
| rs4340655 | 3 | 125681401 | ROPN1B | ENSG00000114547.5 | 2.884E-11 | 0 | -6586 | gtex_brain_putamen_basal |
| rs1827493 | 3 | 125683030 | ROPN1B | ENSG00000114547.5 | 4.833E-10 | 0 | -4957 | gtex_brain_putamen_basal |
| rs1393738 | 3 | 125683161 | ROPN1B | ENSG00000114547.5 | 2.924E-11 | 0 | -4826 | gtex_brain_putamen_basal |
| rs1827492 | 3 | 125683874 | ROPN1B | ENSG00000114547.5 | 2.884E-11 | 0 | -4113 | gtex_brain_putamen_basal |
| rs11715922 | 3 | 125684483 | ROPN1B | ENSG00000114547.5 | 3.042E-10 | 0 | -3504 | gtex_brain_putamen_basal |
| rs63682863 | 3 | 125684510 | ROPN1B | ENSG00000114547.5 | 1.714E-8 | 0 | -3477 | gtex_brain_putamen_basal |
| rs10934739 | 3 | 125685322 | ROPN1B | ENSG00000114547.5 | 2.824E-11 | 0 | -2665 | gtex_brain_putamen_basal |
| rs12630001 | 3 | 125685806 | ROPN1B | ENSG00000114547.5 | 4.502E-8 | 0 | -2181 | gtex_brain_putamen_basal |
| rs4450758 | 3 | 125686761 | ROPN1B | ENSG00000114547.5 | 2.818E-11 | 0 | -1226 | gtex_brain_putamen_basal |
| rs112454226 | 3 | 125686859 | ROPN1B | ENSG00000114547.5 | 1.508E-7 | 0 | -1128 | gtex_brain_putamen_basal |
| rs74601798 | 3 | 125687674 | ROPN1B | ENSG00000114547.5 | 2.605E-7 | 0 | -313 | gtex_brain_putamen_basal |
| rs9856640 | 3 | 125689427 | ROPN1B | ENSG00000114547.5 | 4.723E-7 | 0 | 1440 | gtex_brain_putamen_basal |
| rs7623293 | 3 | 125692141 | ROPN1B | ENSG00000114547.5 | 4.86E-7 | 0 | 4154 | gtex_brain_putamen_basal |
| rs58676015 | 3 | 125692148 | ROPN1B | ENSG00000114547.5 | 1.951E-7 | 0 | 4161 | gtex_brain_putamen_basal |
| rs7638833 | 3 | 125697172 | ROPN1B | ENSG00000114547.5 | 1.23E-6 | 0 | 9185 | gtex_brain_putamen_basal |
| rs11915239 | 3 | 125697468 | ROPN1B | ENSG00000114547.5 | 5.04E-9 | 0 | 9481 | gtex_brain_putamen_basal |
| rs11927101 | 3 | 125697489 | ROPN1B | ENSG00000114547.5 | 2.495E-8 | 0 | 9502 | gtex_brain_putamen_basal |
| rs11925047 | 3 | 125698944 | ROPN1B | ENSG00000114547.5 | 2.266E-8 | 0 | 10957 | gtex_brain_putamen_basal |
| rs34440369 | 3 | 125703330 | ROPN1B | ENSG00000114547.5 | 7.624E-9 | 0 | 15343 | gtex_brain_putamen_basal |
| rs11929488 | 3 | 125703352 | ROPN1B | ENSG00000114547.5 | 1.052E-8 | 0 | 15365 | gtex_brain_putamen_basal |
| rs3796165 | 3 | 125703793 | ROPN1B | ENSG00000114547.5 | 4.48E-9 | 0 | 15806 | gtex_brain_putamen_basal |
| rs6790101 | 3 | 125706012 | ROPN1B | ENSG00000114547.5 | 1.843E-8 | 0 | 18025 | gtex_brain_putamen_basal |
| rs12635522 | 3 | 125708174 | ROPN1B | ENSG00000114547.5 | 9.828E-8 | 0 | 20187 | gtex_brain_putamen_basal |
| rs12636296 | 3 | 125709050 | ROPN1B | ENSG00000114547.5 | 2.152E-8 | 0 | 21063 | gtex_brain_putamen_basal |
| rs12636284 | 3 | 125709213 | ROPN1B | ENSG00000114547.5 | 4.571E-7 | 0 | 21226 | gtex_brain_putamen_basal |
| rs6764694 | 3 | 125709351 | ROPN1B | ENSG00000114547.5 | 2.353E-6 | 0 | 21364 | gtex_brain_putamen_basal |
| rs35120077 | 3 | 125709366 | ROPN1B | ENSG00000114547.5 | 2.159E-8 | 0 | 21379 | gtex_brain_putamen_basal |
| rs12629208 | 3 | 125710383 | ROPN1B | ENSG00000114547.5 | 4.353E-9 | 0 | 22396 | gtex_brain_putamen_basal |
| rs60179307 | 3 | 125712049 | ROPN1B | ENSG00000114547.5 | 2.185E-8 | 0 | 24062 | gtex_brain_putamen_basal |
| rs6781125 | 3 | 125715662 | ROPN1B | ENSG00000114547.5 | 2.337E-6 | 0 | 27675 | gtex_brain_putamen_basal |
| rs28876413 | 3 | 125715737 | ROPN1B | ENSG00000114547.5 | 2.337E-6 | 0 | 27750 | gtex_brain_putamen_basal |
| rs9816066 | 3 | 125720555 | ROPN1B | ENSG00000114547.5 | 2.093E-6 | 0 | 32568 | gtex_brain_putamen_basal |
| rs10804573 | 3 | 125721014 | ROPN1B | ENSG00000114547.5 | 2.328E-6 | 0 | 33027 | gtex_brain_putamen_basal |
| rs397991018 | 3 | 125722293 | ROPN1B | ENSG00000114547.5 | 1.928E-6 | 0 | 34306 | gtex_brain_putamen_basal |
| rs199521497 | 3 | 125722295 | ROPN1B | ENSG00000114547.5 | 3.358E-6 | 0 | 34308 | gtex_brain_putamen_basal |
| rs2279819 | 3 | 125726048 | ROPN1B | ENSG00000114547.5 | 2.318E-6 | 0 | 38061 | gtex_brain_putamen_basal |
| rs1875682 | 3 | 125726890 | ROPN1B | ENSG00000114547.5 | 2.232E-8 | 0 | 38903 | gtex_brain_putamen_basal |
| rs386397853 | 3 | 125730746 | ROPN1B | ENSG00000114547.5 | 2.236E-8 | 0 | 42759 | gtex_brain_putamen_basal |
| rs1566714 | 3 | 125731092 | ROPN1B | ENSG00000114547.5 | 2.236E-8 | 0 | 43105 | gtex_brain_putamen_basal |
| rs3804586 | 3 | 125732531 | ROPN1B | ENSG00000114547.5 | 2.572E-8 | 0 | 44544 | gtex_brain_putamen_basal |
| rs905453 | 3 | 125733003 | ROPN1B | ENSG00000114547.5 | 2.343E-6 | 0 | 45016 | gtex_brain_putamen_basal |
| rs883207 | 3 | 125733081 | ROPN1B | ENSG00000114547.5 | 8.885E-8 | 0 | 45094 | gtex_brain_putamen_basal |
| rs905454 | 3 | 125733125 | ROPN1B | ENSG00000114547.5 | 2.32E-6 | 0 | 45138 | gtex_brain_putamen_basal |
| rs2244835 | 3 | 125733525 | ROPN1B | ENSG00000114547.5 | 2.326E-8 | 0 | 45538 | gtex_brain_putamen_basal |
| rs2279820 | 3 | 125734272 | ROPN1B | ENSG00000114547.5 | 2.326E-8 | 0 | 46285 | gtex_brain_putamen_basal |
| rs9862310 | 3 | 125734465 | ROPN1B | ENSG00000114547.5 | 8.885E-8 | 0 | 46478 | gtex_brain_putamen_basal |
| rs9862567 | 3 | 125734807 | ROPN1B | ENSG00000114547.5 | 8.885E-8 | 0 | 46820 | gtex_brain_putamen_basal |
| rs3792282 | 3 | 125736204 | ROPN1B | ENSG00000114547.5 | 2.326E-8 | 0 | 48217 | gtex_brain_putamen_basal |
| rs3792283 | 3 | 125736338 | ROPN1B | ENSG00000114547.5 | 8.885E-8 | 0 | 48351 | gtex_brain_putamen_basal |
| rs3804587 | 3 | 125737621 | ROPN1B | ENSG00000114547.5 | 2.234E-8 | 0 | 49634 | gtex_brain_putamen_basal |
| rs9817239 | 3 | 125738463 | ROPN1B | ENSG00000114547.5 | 2.314E-6 | 0 | 50476 | gtex_brain_putamen_basal |
| rs9855477 | 3 | 125738709 | ROPN1B | ENSG00000114547.5 | 9.256E-8 | 0 | 50722 | gtex_brain_putamen_basal |
| rs7647098 | 3 | 125739695 | ROPN1B | ENSG00000114547.5 | 3.253E-8 | 0 | 51708 | gtex_brain_putamen_basal |
| rs7647107 | 3 | 125739717 | ROPN1B | ENSG00000114547.5 | 1.272E-7 | 0 | 51730 | gtex_brain_putamen_basal |
| rs11925965 | 3 | 125740393 | ROPN1B | ENSG00000114547.5 | 1.419E-7 | 0 | 52406 | gtex_brain_putamen_basal |
| rs10934742 | 3 | 125740788 | ROPN1B | ENSG00000114547.5 | 1.419E-7 | 0 | 52801 | gtex_brain_putamen_basal |
| rs7634120 | 3 | 125741230 | ROPN1B | ENSG00000114547.5 | 1.419E-7 | 0 | 53243 | gtex_brain_putamen_basal |
| rs7633958 | 3 | 125741256 | ROPN1B | ENSG00000114547.5 | 1.422E-7 | 0 | 53269 | gtex_brain_putamen_basal |
| rs7645814 | 3 | 125741333 | ROPN1B | ENSG00000114547.5 | 1.463E-6 | 0 | 53346 | gtex_brain_putamen_basal |
| rs7634234 | 3 | 125741352 | ROPN1B | ENSG00000114547.5 | 1.676E-7 | 0 | 53365 | gtex_brain_putamen_basal |
| rs3817079 | 3 | 125741592 | ROPN1B | ENSG00000114547.5 | 2.955E-7 | 0 | 53605 | gtex_brain_putamen_basal |
| rs2270984 | 3 | 125741901 | ROPN1B | ENSG00000114547.5 | 1.419E-7 | 0 | 53914 | gtex_brain_putamen_basal |
| rs2270983 | 3 | 125741925 | ROPN1B | ENSG00000114547.5 | 2.955E-7 | 0 | 53938 | gtex_brain_putamen_basal |
| rs12630606 | 3 | 125742108 | ROPN1B | ENSG00000114547.5 | 1.419E-7 | 0 | 54121 | gtex_brain_putamen_basal |
| rs11928117 | 3 | 125742436 | ROPN1B | ENSG00000114547.5 | 1.419E-7 | 0 | 54449 | gtex_brain_putamen_basal |
| rs879385 | 3 | 125744073 | ROPN1B | ENSG00000114547.5 | 2.957E-7 | 0 | 56086 | gtex_brain_putamen_basal |
| rs879386 | 3 | 125744147 | ROPN1B | ENSG00000114547.5 | 2.955E-7 | 0 | 56160 | gtex_brain_putamen_basal |
| rs7646705 | 3 | 125745433 | ROPN1B | ENSG00000114547.5 | 1.676E-7 | 0 | 57446 | gtex_brain_putamen_basal |
| rs7649483 | 3 | 125745874 | ROPN1B | ENSG00000114547.5 | 2.946E-7 | 0 | 57887 | gtex_brain_putamen_basal |
| rs71327748 | 3 | 125746967 | ROPN1B | ENSG00000114547.5 | 1.422E-7 | 0 | 58980 | gtex_brain_putamen_basal |
| rs34923610 | 3 | 125747170 | ROPN1B | ENSG00000114547.5 | 1.422E-7 | 0 | 59183 | gtex_brain_putamen_basal |
| rs34326152 | 3 | 125748858 | ROPN1B | ENSG00000114547.5 | 1.702E-7 | 0 | 60871 | gtex_brain_putamen_basal |
| rs12631986 | 3 | 125749810 | ROPN1B | ENSG00000114547.5 | 1.676E-7 | 0 | 61823 | gtex_brain_putamen_basal |
| rs2333407 | 3 | 125750422 | ROPN1B | ENSG00000114547.5 | 1.676E-7 | 0 | 62435 | gtex_brain_putamen_basal |
| rs868149 | 3 | 125750857 | ROPN1B | ENSG00000114547.5 | 1.676E-7 | 0 | 62870 | gtex_brain_putamen_basal |
| rs6438958 | 3 | 125751135 | ROPN1B | ENSG00000114547.5 | 2.956E-7 | 0 | 63148 | gtex_brain_putamen_basal |
| rs9840962 | 3 | 125751632 | ROPN1B | ENSG00000114547.5 | 2.956E-7 | 0 | 63645 | gtex_brain_putamen_basal |
| rs13077514 | 3 | 125751853 | ROPN1B | ENSG00000114547.5 | 1.504E-7 | 0 | 63866 | gtex_brain_putamen_basal |
| rs55924097 | 3 | 125752272 | ROPN1B | ENSG00000114547.5 | 1.676E-7 | 0 | 64285 | gtex_brain_putamen_basal |
| rs13090202 | 3 | 125754505 | ROPN1B | ENSG00000114547.5 | 4.537E-8 | 0 | 66518 | gtex_brain_putamen_basal |
| rs4552306 | 3 | 125754867 | ROPN1B | ENSG00000114547.5 | 2.304E-8 | 0 | 66880 | gtex_brain_putamen_basal |
| rs3059797 | 3 | 125755502 | ROPN1B | ENSG00000114547.5 | 1.702E-7 | 0 | 67515 | gtex_brain_putamen_basal |
| rs1008066 | 3 | 125755889 | ROPN1B | ENSG00000114547.5 | 1.676E-7 | 0 | 67902 | gtex_brain_putamen_basal |
| rs1008067 | 3 | 125756031 | ROPN1B | ENSG00000114547.5 | 1.676E-7 | 0 | 68044 | gtex_brain_putamen_basal |
| rs2134520 | 3 | 125756295 | ROPN1B | ENSG00000114547.5 | 2.364E-8 | 0 | 68308 | gtex_brain_putamen_basal |
| rs13070943 | 3 | 125756775 | ROPN1B | ENSG00000114547.5 | 1.676E-7 | 0 | 68788 | gtex_brain_putamen_basal |
| rs4560250 | 3 | 125756918 | ROPN1B | ENSG00000114547.5 | 2.364E-8 | 0 | 68931 | gtex_brain_putamen_basal |
| rs11919548 | 3 | 125758932 | ROPN1B | ENSG00000114547.5 | 2.571E-8 | 0 | 70945 | gtex_brain_putamen_basal |
| rs1503073 | 3 | 125759232 | ROPN1B | ENSG00000114547.5 | 2.191E-8 | 0 | 71245 | gtex_brain_putamen_basal |
| rs11919781 | 3 | 125759480 | ROPN1B | ENSG00000114547.5 | 2.571E-8 | 0 | 71493 | gtex_brain_putamen_basal |
| rs12633421 | 3 | 125760349 | ROPN1B | ENSG00000114547.5 | 2.571E-8 | 0 | 72362 | gtex_brain_putamen_basal |
| rs35332488 | 3 | 125761747 | ROPN1B | ENSG00000114547.5 | 2.571E-8 | 0 | 73760 | gtex_brain_putamen_basal |
| rs6438960 | 3 | 125762131 | ROPN1B | ENSG00000114547.5 | 2.571E-8 | 0 | 74144 | gtex_brain_putamen_basal |
| rs6789129 | 3 | 125762352 | ROPN1B | ENSG00000114547.5 | 2.365E-8 | 0 | 74365 | gtex_brain_putamen_basal |
| rs6438961 | 3 | 125762402 | ROPN1B | ENSG00000114547.5 | 2.574E-8 | 0 | 74415 | gtex_brain_putamen_basal |
| rs6778845 | 3 | 125762636 | ROPN1B | ENSG00000114547.5 | 2.364E-8 | 0 | 74649 | gtex_brain_putamen_basal |
| rs201133884 | 3 | 125762648 | ROPN1B | ENSG00000114547.5 | 4.162E-8 | 0 | 74661 | gtex_brain_putamen_basal |
| rs548688983 | 3 | 125762665 | ROPN1B | ENSG00000114547.5 | 9.767E-9 | 0 | 74678 | gtex_brain_putamen_basal |
| rs13070081 | 3 | 125763369 | ROPN1B | ENSG00000114547.5 | 1.676E-7 | 0 | 75382 | gtex_brain_putamen_basal |
| rs6806332 | 3 | 125763566 | ROPN1B | ENSG00000114547.5 | 2.596E-8 | 0 | 75579 | gtex_brain_putamen_basal |
| rs6806350 | 3 | 125763632 | ROPN1B | ENSG00000114547.5 | 4.853E-7 | 0 | 75645 | gtex_brain_putamen_basal |
| rs71327749 | 3 | 125763893 | ROPN1B | ENSG00000114547.5 | 2.839E-7 | 0 | 75906 | gtex_brain_putamen_basal |
| rs397811842 | 3 | 125764655 | ROPN1B | ENSG00000114547.5 | 2.783E-8 | 0 | 76668 | gtex_brain_putamen_basal |
| rs59335896 | 3 | 125765603 | ROPN1B | ENSG00000114547.5 | 1.479E-8 | 0 | 77616 | gtex_brain_putamen_basal |
| rs6764781 | 3 | 125765624 | ROPN1B | ENSG00000114547.5 | 2.991E-8 | 0 | 77637 | gtex_brain_putamen_basal |
| rs7612322 | 3 | 125765800 | ROPN1B | ENSG00000114547.5 | 2.565E-8 | 0 | 77813 | gtex_brain_putamen_basal |
| rs12639251 | 3 | 125766262 | ROPN1B | ENSG00000114547.5 | 5.731E-7 | 0 | 78275 | gtex_brain_putamen_basal |
| rs4521174 | 3 | 125766786 | ROPN1B | ENSG00000114547.5 | 5.89E-9 | 0 | 78799 | gtex_brain_putamen_basal |
| rs4542969 | 3 | 125767042 | ROPN1B | ENSG00000114547.5 | 2.364E-8 | 0 | 79055 | gtex_brain_putamen_basal |
| rs9849490 | 3 | 125767403 | ROPN1B | ENSG00000114547.5 | 2.957E-7 | 0 | 79416 | gtex_brain_putamen_basal |
| rs34828359 | 3 | 125767409 | ROPN1B | ENSG00000114547.5 | 1.419E-7 | 0 | 79422 | gtex_brain_putamen_basal |
| rs13067299 | 3 | 125767964 | ROPN1B | ENSG00000114547.5 | 1.231E-7 | 0 | 79977 | gtex_brain_putamen_basal |
| rs34633518 | 3 | 125769375 | ROPN1B | ENSG00000114547.5 | 2.709E-7 | 0 | 81388 | gtex_brain_putamen_basal |
| rs4076728 | 3 | 125770163 | ROPN1B | ENSG00000114547.5 | 1.676E-7 | 0 | 82176 | gtex_brain_putamen_basal |
| rs4128151 | 3 | 125770302 | ROPN1B | ENSG00000114547.5 | 2.709E-7 | 0 | 82315 | gtex_brain_putamen_basal |
| rs75058312 | 3 | 125770319 | ROPN1B | ENSG00000114547.5 | 1.676E-7 | 0 | 82332 | gtex_brain_putamen_basal |
| rs35839813 | 3 | 125770743 | ROPN1B | ENSG00000114547.5 | 1.676E-7 | 0 | 82756 | gtex_brain_putamen_basal |
| rs9815733 | 3 | 125771580 | ROPN1B | ENSG00000114547.5 | 1.312E-7 | 0 | 83593 | gtex_brain_putamen_basal |
| rs9815750 | 3 | 125771644 | ROPN1B | ENSG00000114547.5 | 1.312E-7 | 0 | 83657 | gtex_brain_putamen_basal |
| rs12630605 | 3 | 125772195 | ROPN1B | ENSG00000114547.5 | 1.697E-7 | 0 | 84208 | gtex_brain_putamen_basal |
| rs6795856 | 3 | 125773218 | ROPN1B | ENSG00000114547.5 | 1.53E-7 | 0 | 85231 | gtex_brain_putamen_basal |
| rs6808519 | 3 | 125773438 | ROPN1B | ENSG00000114547.5 | 1.532E-7 | 0 | 85451 | gtex_brain_putamen_basal |
| rs6799100 | 3 | 125773885 | ROPN1B | ENSG00000114547.5 | 1.53E-7 | 0 | 85898 | gtex_brain_putamen_basal |
| rs7432425 | 3 | 125774321 | ROPN1B | ENSG00000114547.5 | 1.676E-7 | 0 | 86334 | gtex_brain_putamen_basal |
| rs6438963 | 3 | 125774854 | ROPN1B | ENSG00000114547.5 | 2.084E-7 | 0 | 86867 | gtex_brain_putamen_basal |
| rs6438964 | 3 | 125775428 | ROPN1B | ENSG00000114547.5 | 1.53E-7 | 0 | 87441 | gtex_brain_putamen_basal |
| rs6805596 | 3 | 125775818 | ROPN1B | ENSG00000114547.5 | 1.53E-7 | 0 | 87831 | gtex_brain_putamen_basal |
| rs4546107 | 3 | 125776173 | ROPN1B | ENSG00000114547.5 | 1.53E-7 | 0 | 88186 | gtex_brain_putamen_basal |
| rs9869721 | 3 | 125776614 | ROPN1B | ENSG00000114547.5 | 1.53E-7 | 0 | 88627 | gtex_brain_putamen_basal |
| rs9837077 | 3 | 125777661 | ROPN1B | ENSG00000114547.5 | 1.53E-7 | 0 | 89674 | gtex_brain_putamen_basal |
| rs9875224 | 3 | 125777695 | ROPN1B | ENSG00000114547.5 | 1.53E-7 | 0 | 89708 | gtex_brain_putamen_basal |
| rs7633452 | 3 | 125778150 | ROPN1B | ENSG00000114547.5 | 1.035E-6 | 0 | 90163 | gtex_brain_putamen_basal |
| rs9714340 | 3 | 125778154 | ROPN1B | ENSG00000114547.5 | 1.986E-7 | 0 | 90167 | gtex_brain_putamen_basal |
| rs4679202 | 3 | 125779468 | ROPN1B | ENSG00000114547.5 | 1.527E-7 | 0 | 91481 | gtex_brain_putamen_basal |
| rs4449265 | 3 | 125779652 | ROPN1B | ENSG00000114547.5 | 1.527E-7 | 0 | 91665 | gtex_brain_putamen_basal |
| rs35047628 | 3 | 125780301 | ROPN1B | ENSG00000114547.5 | 2.703E-7 | 0 | 92314 | gtex_brain_putamen_basal |
| rs4679203 | 3 | 125780347 | ROPN1B | ENSG00000114547.5 | 1.527E-7 | 0 | 92360 | gtex_brain_putamen_basal |
| rs4413273 | 3 | 125780697 | ROPN1B | ENSG00000114547.5 | 1.527E-7 | 0 | 92710 | gtex_brain_putamen_basal |
| rs9845531 | 3 | 125782158 | ROPN1B | ENSG00000114547.5 | 1.53E-7 | 0 | 94171 | gtex_brain_putamen_basal |
| rs13083168 | 3 | 125782946 | ROPN1B | ENSG00000114547.5 | 2.709E-7 | 0 | 94959 | gtex_brain_putamen_basal |
| rs12054002 | 3 | 125782973 | ROPN1B | ENSG00000114547.5 | 1.53E-7 | 0 | 94986 | gtex_brain_putamen_basal |
| rs7632595 | 3 | 125783232 | ROPN1B | ENSG00000114547.5 | 1.53E-7 | 0 | 95245 | gtex_brain_putamen_basal |
| rs7610786 | 3 | 125783285 | ROPN1B | ENSG00000114547.5 | 1.53E-7 | 0 | 95298 | gtex_brain_putamen_basal |
| rs4286389 | 3 | 125783600 | ROPN1B | ENSG00000114547.5 | 1.588E-7 | 0 | 95613 | gtex_brain_putamen_basal |
| rs4493383 | 3 | 125783690 | ROPN1B | ENSG00000114547.5 | 1.53E-7 | 0 | 95703 | gtex_brain_putamen_basal |
| rs4679204 | 3 | 125784134 | ROPN1B | ENSG00000114547.5 | 1.53E-7 | 0 | 96147 | gtex_brain_putamen_basal |
| rs4679205 | 3 | 125784252 | ROPN1B | ENSG00000114547.5 | 1.53E-7 | 0 | 96265 | gtex_brain_putamen_basal |
| rs6438965 | 3 | 125785315 | ROPN1B | ENSG00000114547.5 | 1.53E-7 | 0 | 97328 | gtex_brain_putamen_basal |
| rs202081037 | 3 | 125785939 | ROPN1B | ENSG00000114547.5 | 7.879E-7 | 0 | 97952 | gtex_brain_putamen_basal |
| rs4308225 | 3 | 125786695 | ROPN1B | ENSG00000114547.5 | 1.53E-7 | 0 | 98708 | gtex_brain_putamen_basal |
| rs4308226 | 3 | 125786760 | ROPN1B | ENSG00000114547.5 | 1.53E-7 | 0 | 98773 | gtex_brain_putamen_basal |
| rs4314124 | 3 | 125787632 | ROPN1B | ENSG00000114547.5 | 1.676E-7 | 0 | 99645 | gtex_brain_putamen_basal |
| rs4679206 | 3 | 125788421 | ROPN1B | ENSG00000114547.5 | 3.049E-7 | 0 | 100434 | gtex_brain_putamen_basal |
| rs6796702 | 3 | 125791014 | ROPN1B | ENSG00000114547.5 | 4.503E-7 | 0 | 103027 | gtex_brain_putamen_basal |
| rs13100420 | 3 | 125791543 | ROPN1B | ENSG00000114547.5 | 1.676E-7 | 0 | 103556 | gtex_brain_putamen_basal |
| rs13070157 | 3 | 125793768 | ROPN1B | ENSG00000114547.5 | 2.72E-7 | 0 | 105781 | gtex_brain_putamen_basal |
| rs11920522 | 3 | 125795551 | ROPN1B | ENSG00000114547.5 | 2.709E-7 | 0 | 107564 | gtex_brain_putamen_basal |
| rs11925450 | 3 | 125795874 | ROPN1B | ENSG00000114547.5 | 2.709E-7 | 0 | 107887 | gtex_brain_putamen_basal |
| rs11925456 | 3 | 125795893 | ROPN1B | ENSG00000114547.5 | 2.709E-7 | 0 | 107906 | gtex_brain_putamen_basal |
| rs6796610 | 3 | 125797913 | ROPN1B | ENSG00000114547.5 | 1.676E-7 | 0 | 109926 | gtex_brain_putamen_basal |
| rs71150423 | 3 | 125801634 | ROPN1B | ENSG00000114547.5 | 5.603E-8 | 0 | 113647 | gtex_brain_putamen_basal |
| rs200816951 | 3 | 125805250 | ROPN1B | ENSG00000114547.5 | 4.547E-7 | 0 | 117263 | gtex_brain_putamen_basal |
| rs60432833 | 3 | 125806900 | ROPN1B | ENSG00000114547.5 | 2.88E-8 | 0 | 118913 | gtex_brain_putamen_basal |
| rs4447711 | 3 | 125809715 | ROPN1B | ENSG00000114547.5 | 5.635E-7 | 0 | 121728 | gtex_brain_putamen_basal |
| rs71327750 | 3 | 125815056 | ROPN1B | ENSG00000114547.5 | 3.332E-7 | 0 | 127069 | gtex_brain_putamen_basal |
| rs34049220 | 3 | 125815634 | ROPN1B | ENSG00000114547.5 | 3.586E-8 | 0 | 127647 | gtex_brain_putamen_basal |
| rs2365012 | 3 | 125817204 | ROPN1B | ENSG00000114547.5 | 6.446E-7 | 0 | 129217 | gtex_brain_putamen_basal |
| rs2365011 | 3 | 125817218 | ROPN1B | ENSG00000114547.5 | 4.046E-8 | 0 | 129231 | gtex_brain_putamen_basal |
| rs1077620 | 3 | 125819540 | ROPN1B | ENSG00000114547.5 | 3.964E-8 | 0 | 131553 | gtex_brain_putamen_basal |
| rs2004338 | 3 | 125819737 | ROPN1B | ENSG00000114547.5 | 6.332E-7 | 0 | 131750 | gtex_brain_putamen_basal |
| rs4646768 | 3 | 125820571 | ROPN1B | ENSG00000114547.5 | 9.504E-7 | 0 | 132584 | gtex_brain_putamen_basal |
| rs2003334 | 3 | 125822003 | ROPN1B | ENSG00000114547.5 | 6.332E-7 | 0 | 134016 | gtex_brain_putamen_basal |
| rs4646762 | 3 | 125822178 | ROPN1B | ENSG00000114547.5 | 7.078E-7 | 0 | 134191 | gtex_brain_putamen_basal |
| rs4646761 | 3 | 125822272 | ROPN1B | ENSG00000114547.5 | 9.504E-7 | 0 | 134285 | gtex_brain_putamen_basal |
| rs4646760 | 3 | 125822871 | ROPN1B | ENSG00000114547.5 | 6.499E-7 | 0 | 134884 | gtex_brain_putamen_basal |
| rs4646755 | 3 | 125824334 | ROPN1B | ENSG00000114547.5 | 1.411E-7 | 0 | 136347 | gtex_brain_putamen_basal |
| rs10934744 | 3 | 125824382 | ROPN1B | ENSG00000114547.5 | 1.602E-6 | 0 | 136395 | gtex_brain_putamen_basal |
| rs4646754 | 3 | 125824899 | ROPN1B | ENSG00000114547.5 | 1.604E-6 | 0 | 136912 | gtex_brain_putamen_basal |
| rs4646751 | 3 | 125825661 | ROPN1B | ENSG00000114547.5 | 2.421E-6 | 0 | 137674 | gtex_brain_putamen_basal |
| rs2276730 | 3 | 125826213 | ROPN1B | ENSG00000114547.5 | 2.512E-6 | 0 | 138226 | gtex_brain_putamen_basal |
Section II. Transcriptome annotation
General gene expression (GTEx)
Gene expression of temporal and spatial changes (BrainSpan)
Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes the lower 25% and upper 25% of the expression distribution.
Top co-expressed genes in brain regions
| Top 10 positively co-expressed genes | ||
| Gene | Pearson's Correlation | Spearman's Correlation |
| L3MBTL4 | 0.79 | 0.79 |
| MAF | 0.73 | 0.82 |
| LMO4 | 0.71 | 0.75 |
| MAFB | 0.70 | 0.82 |
| UST | 0.70 | 0.75 |
| NTN4 | 0.69 | 0.74 |
| NDST3 | 0.69 | 0.72 |
| BMP2 | 0.68 | 0.70 |
| ETV6 | 0.67 | 0.70 |
| ZSCAN18 | 0.67 | 0.80 |
| Top 10 negatively co-expressed genes | ||
| Gene | Pearson's Correlation | Spearman's Correlation |
| MT-CO2 | -0.46 | -0.49 |
| AF347015.21 | -0.46 | -0.49 |
| AF347015.31 | -0.45 | -0.47 |
| AF347015.33 | -0.45 | -0.44 |
| AF347015.8 | -0.44 | -0.47 |
| MT-CYB | -0.44 | -0.45 |
| AF347015.27 | -0.43 | -0.46 |
| S100B | -0.42 | -0.42 |
| AF347015.26 | -0.42 | -0.43 |
| AC021016.1 | -0.42 | -0.43 |
Section V. Pathway annotation
| Pathway name | Pathway size | # SZGR 2.0 genes in pathway | Info |
|---|---|---|---|
| ONKEN UVEAL MELANOMA DN | 526 | 357 | All SZGR 2.0 genes in this pathway |
| TURASHVILI BREAST DUCTAL CARCINOMA VS LOBULAR NORMAL DN | 69 | 43 | All SZGR 2.0 genes in this pathway |
| DOANE BREAST CANCER ESR1 DN | 48 | 28 | All SZGR 2.0 genes in this pathway |
| DODD NASOPHARYNGEAL CARCINOMA UP | 1821 | 933 | All SZGR 2.0 genes in this pathway |
| SMID BREAST CANCER RELAPSE IN BONE DN | 315 | 197 | All SZGR 2.0 genes in this pathway |
| SMID BREAST CANCER LUMINAL B DN | 564 | 326 | All SZGR 2.0 genes in this pathway |
| SMID BREAST CANCER BASAL UP | 648 | 398 | All SZGR 2.0 genes in this pathway |