Gene Page: TMEM74
Summary ?
| GeneID | 157753 |
| Symbol | TMEM74 |
| Synonyms | NET36 |
| Description | transmembrane protein 74 |
| Reference | MIM:613935|HGNC:HGNC:26409|HPRD:08702| |
| Gene type | protein-coding |
| Map location | 8q23.1 |
| Pascal p-value | 0.035 |
| Sherlock p-value | 0.295 |
| eGene | Myers' cis & trans |
Gene in Data Sources
| Gene set name | Method of gene set | Description | Info |
|---|---|---|---|
| CV:PGCnp | Genome-wide Association Study | GWAS |
Section I. Genetics and epigenetics annotation
eQTL annotation
| SNP ID | Chromosome | Position | eGene | Gene Entrez ID | pvalue | qvalue | TSS distance | eQTL type |
|---|---|---|---|---|---|---|---|---|
| rs828895 | chr2 | 74339309 | TMEM74 | 157753 | 0.05 | trans | ||
| rs16829545 | chr2 | 151977407 | TMEM74 | 157753 | 0 | trans | ||
| rs17018961 | chr4 | 92869523 | TMEM74 | 157753 | 0.19 | trans | ||
| rs3208856 | chr19 | 45296805 | TMEM74 | 157753 | 0.13 | trans | ||
| rs9637082 | chr21 | 21213235 | TMEM74 | 157753 | 0.18 | trans |
Section II. Transcriptome annotation
General gene expression (GTEx)
Gene expression of temporal and spatial changes (BrainSpan)
Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes the lower 25% and upper 25% of the expression distribution.
No co-expressed genes in brain regions
Section V. Pathway annotation
| Pathway name | Pathway size | # SZGR 2.0 genes in pathway | Info |
|---|---|---|---|
| NIKOLSKY BREAST CANCER 8Q23 Q24 AMPLICON | 157 | 87 | All SZGR 2.0 genes in this pathway |
| LIN NPAS4 TARGETS UP | 163 | 100 | All SZGR 2.0 genes in this pathway |
| MARTENS TRETINOIN RESPONSE UP | 857 | 456 | All SZGR 2.0 genes in this pathway |
| HOELZEL NF1 TARGETS UP | 139 | 93 | All SZGR 2.0 genes in this pathway |