Gene Page: DAZL

Summary
GeneID  1618
Symbol  DAZL
Synonyms  DAZH|DAZL1|DAZLA|MGC26406|SPGYLA
Description  deleted in azoospermia-like
See related  HGNC:2685|MIM:601486|Ensembl:ENSG00000092345|HPRD:09029|
Locus tag  -
Gene type  protein-coding
Map location  3p24.3
 
Gene in Data Sources
Gene set name Method of gene set Evidence Info
GSMA_Igenome scan meta-analysisPsr: 0.006 
 
General Gene Expression (microarray) ?
 
Gene Expression in Brain Regions (new)
 
Top co-expressed genes in Brain Regions (new)
GenePearson's Correlation Spearman's Correlation
Top 10 positively co-expressed genes
NFIA0.870.77
IGSF30.850.91
NFIB0.850.86
XPR10.850.92
BCL11A0.840.85
ITSN10.840.84
EPHB10.840.81
NFYA0.840.90
VANGL20.840.81
C10orf120.840.90
Top 10 negatively co-expressed genes
TNFSF12-0.52-0.64
C5orf53-0.52-0.76
TMEM54-0.51-0.56
PTH1R-0.50-0.72
LHPP-0.50-0.58
AIFM3-0.50-0.77
SERPINB6-0.50-0.70
HLA-F-0.49-0.72
HEPN1-0.49-0.72
SLC9A3R2-0.49-0.47
Gene Ontology
Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0000166nucleotide bindingIEA-
GO:0003676nucleic acid bindingIEA-
GO:0003723RNA bindingTAS8968755 
GO:0003730mRNA 3'-UTR bindingIEA-
GO:0005515protein bindingIPI16001084 
GO:0008494translation activator activityIDA16001084 
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0006417regulation of translationIEA-
GO:0007283spermatogenesisIEA-
GO:0007281germ cell developmentTAS9288969 
GO:0007275multicellular organismal developmentIEA-
GO:0030154cell differentiationIEA-
GO:0045948positive regulation of translational initiationIDA16001084 
GO:0045836positive regulation of meiosisIEA-
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0005844polysomeIEA-
GO:0005634nucleusIEA-
GO:0005737cytoplasmTAS9288969 
 
InteractionsShown by Network
InteractorsAliases BOfficial full name BExperimentalSourcePubMed ID
DAZ1DAZ | SPGYdeleted in azoospermia 1-HPRD,BioGRID10857750 
DAZ4DAZ | DAZ1 | pDP1680 | pDP1681deleted in azoospermia 4-HPRD12511597 
DAZAP1MGC19907DAZ associated protein 1-HPRD,BioGRID10857750 
DAZAP2KIAA0058 | MGC14319 | MGC766 | PRTBDAZ associated protein 2-HPRD,BioGRID10857750 
DAZLDAZH | DAZL1 | DAZLA | MGC26406 | SPGYLAdeleted in azoospermia-like-HPRD,BioGRID10903443 
PUM2FLJ36528 | KIAA0235 | MGC138251 | MGC138253 | PUMH2 | PUML2pumilio homolog 2 (Drosophila)-HPRD12511597 
 
Pathway annotation
Pathway namePathway size# SZGR genes in pathwayInfo
KIM_RESPONSE_TO_TSA_AND_DECITABINE_UP 12973All SZGR genes in this pathway
ZHONG_RESPONSE_TO_AZACITIDINE_AND_TSA_UP 183119All SZGR genes in this pathway
MUELLER_METHYLATED_IN_GLIOBLASTOMA 4022All SZGR genes in this pathway
LIEN_BREAST_CARCINOMA_METAPLASTIC_VS_DUCTAL_UP 8351All SZGR genes in this pathway
KLEIN_PRIMARY_EFFUSION_LYMPHOMA_UP 5129All SZGR genes in this pathway
LIANG_SILENCED_BY_METHYLATION_2 5334All SZGR genes in this pathway
SU_TESTIS 7653All SZGR genes in this pathway
SATO_SILENCED_EPIGENETICALLY_IN_PANCREATIC_CANCER 4930All SZGR genes in this pathway
JACKSON_DNMT1_TARGETS_UP 7757All SZGR genes in this pathway
CHEN_ETV5_TARGETS_TESTIS 2314All SZGR genes in this pathway
HELLER_SILENCED_BY_METHYLATION_UP 282183All SZGR genes in this pathway
HELLER_HDAC_TARGETS_SILENCED_BY_METHYLATION_UP 461298All SZGR genes in this pathway
WEBER_METHYLATED_HCP_IN_FIBROBLAST_DN 4222All SZGR genes in this pathway
WEBER_METHYLATED_HCP_IN_SPERM_UP 2013All SZGR genes in this pathway
MATZUK_EMBRYONIC_GERM_CELL 1916All SZGR genes in this pathway
MATZUK_SPERMATOGONIA 2417All SZGR genes in this pathway
CONRAD_GERMLINE_STEM_CELL 138All SZGR genes in this pathway
SASAI_TARGETS_OF_CXCR6_AND_PTCH1_DN 86All SZGR genes in this pathway
MEISSNER_NPC_HCP_WITH_H3_UNMETHYLATED 536296All SZGR genes in this pathway
BROWNE_HCMV_INFECTION_2HR_UP 3930All SZGR genes in this pathway
WAGSCHAL_EHMT2_TARGETS_UP 137All SZGR genes in this pathway
MADAN_DPPA4_TARGETS 4626All SZGR genes in this pathway
ACEVEDO_FGFR1_TARGETS_IN_PROSTATE_CANCER_MODEL_UP 289184All SZGR genes in this pathway
miRNA Targets ?
miRNA familyTarget positionmiRNA IDmiRNA seq
UTR startUTR endMatch method
miR-140100010071A,m8hsa-miR-140brainAGUGGUUUUACCCUAUGGUAG
miR-21719725m8hsa-miR-21brainUAGCUUAUCAGACUGAUGUUGA
hsa-miR-590GAGCUUAUUCAUAAAAGUGCAG
miR-3638028081Ahsa-miR-363AUUGCACGGUAUCCAUCUGUAA
miR-378*5615671Ahsa-miR-422bCUGGACUUGGAGUCAGAAGGCC
hsa-miR-422aCUGGACUUAGGGUCAGAAGGCC
  • SZ: miRNAs which differentially expressed in brain cortex of schizophrenia patients comparing with control samples using microarray. Click here to see the list of SZ related miRNAs.
  • Brain: miRNAs which are expressed in brain based on miRNA microarray expression studies. Click here to see the list of brain related miRNAs.


Copyright © Bioinformatics and Systems Medicine Laboratory All Rights Reserved since 2009.