Gene Page: EFNA5

Summary
GeneID  1946
Symbol  EFNA5
Synonyms  AF1|EFL5|EPLG7|GLC1M|LERK7|RAGS
Description  ephrin-A5
See related  HGNC:3225|MIM:601535|Ensembl:ENSG00000184349|HPRD:03324|
Locus tag  -
Gene type  protein-coding
Map location  5q21
 
Gene in Data Sources
Gene set name Method of gene set Evidence Info
GO_AnnotationMapping neuro-related keywords to Gene Ontology annotationsHits with neuro-related keywords: 1 
 
General Gene Expression (microarray) ?
 
Gene Expression in Brain Regions (new)
 
Top co-expressed genes in Brain Regions (new)
GenePearson's Correlation Spearman's Correlation
Top 10 positively co-expressed genes
EGR10.900.92
ARC0.890.81
EGR30.860.82
CX3CL10.840.81
EGR40.840.86
ADAMTS80.820.80
DUSP60.820.79
CACNG30.810.77
FMNL10.810.78
IQSEC20.800.72
Top 10 negatively co-expressed genes
BCL7C-0.45-0.61
RPL23A-0.44-0.57
HEBP2-0.43-0.64
GTF3C6-0.43-0.49
DYNLT1-0.42-0.60
TRAF4-0.42-0.53
TUBB2B-0.41-0.54
EXOSC8-0.41-0.46
FADS2-0.41-0.45
UBE2L6-0.41-0.36
Gene Ontology
Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0046875ephrin receptor bindingTAS9245480 
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0007399nervous system developmentTASneurite (GO term level: 5)9245480 
GO:0007267cell-cell signalingTAS9245480 
GO:0007275multicellular organismal developmentIEA-
GO:0030154cell differentiationIEA-
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0005615extracellular spaceTAS9245480 
GO:0005886plasma membraneIEA-
GO:0046658anchored to plasma membraneTAS9245480 
 
InteractionsShown by Network
InteractorsAliases BOfficial full name BExperimentalSourcePubMed ID
EPHA2ECKEPH receptor A2-HPRD9245480 
EPHA3ETK | ETK1 | HEK | HEK4 | TYRO4EPH receptor A3-HPRD,BioGRID9195962 
-HPRD9195962|9751130 
EPHA5CEK7 | EHK1 | HEK7 | TYRO4EPH receptor A5The membrane bound ligand AL-1 interacts with the receptor EHK1. This interaction was modeled on a demonstrated interaction between AL-1 from human and EHK1 from rat.BIND8755474 
-HPRD10531456 
EPHA7EHK3 | HEK11EPH receptor A7Affinity Capture-WesternBioGRID10366629 
EPHA8EEK | HEK3 | KIAA1459EPH receptor A8-HPRD11416136 
EPHB1ELK | EPHT2 | FLJ37986 | Hek6 | NETEPH receptor B1-HPRD,BioGRID9245480 
 
Pathway annotation
Pathway namePathway size# SZGR genes in pathwayInfo
KEGG_AXON_GUIDANCE 129103All SZGR genes in this pathway
PID_EPHB_FWD_PATHWAY 4038All SZGR genes in this pathway
PID_EPHA_FWDPATHWAY 3429All SZGR genes in this pathway
GAZDA_DIAMOND_BLACKFAN_ANEMIA_ERYTHROID_DN 493298All SZGR genes in this pathway
THUM_SYSTOLIC_HEART_FAILURE_UP 423283All SZGR genes in this pathway
RODRIGUES_THYROID_CARCINOMA_ANAPLASTIC_UP 722443All SZGR genes in this pathway
RODRIGUES_THYROID_CARCINOMA_DN 7752All SZGR genes in this pathway
GRAESSMANN_APOPTOSIS_BY_DOXORUBICIN_DN 17811082All SZGR genes in this pathway
GAUSSMANN_MLL_AF4_FUSION_TARGETS_A_DN 9061All SZGR genes in this pathway
DACOSTA_UV_RESPONSE_VIA_ERCC3_DN 855609All SZGR genes in this pathway
MARTORIATI_MDM4_TARGETS_FETAL_LIVER_DN 514319All SZGR genes in this pathway
DAIRKEE_TERT_TARGETS_DN 12479All SZGR genes in this pathway
GROSS_HYPOXIA_VIA_ELK3_UP 209139All SZGR genes in this pathway
NUYTTEN_EZH2_TARGETS_UP 1037673All SZGR genes in this pathway
NOUZOVA_METHYLATED_IN_APL 6839All SZGR genes in this pathway
ULE_SPLICING_VIA_NOVA2 4338All SZGR genes in this pathway
VERRECCHIA_RESPONSE_TO_TGFB1_C5 2111All SZGR genes in this pathway
VERRECCHIA_DELAYED_RESPONSE_TO_TGFB1 3926All SZGR genes in this pathway
XU_GH1_AUTOCRINE_TARGETS_DN 14294All SZGR genes in this pathway
CREIGHTON_ENDOCRINE_THERAPY_RESISTANCE_3 720440All SZGR genes in this pathway
KONDO_COLON_CANCER_HCP_WITH_H3K27ME1 2613All SZGR genes in this pathway
TAYLOR_METHYLATED_IN_ACUTE_LYMPHOBLASTIC_LEUKEMIA 7752All SZGR genes in this pathway
WANG_TUMOR_INVASIVENESS_DN 210128All SZGR genes in this pathway
VART_KSHV_INFECTION_ANGIOGENIC_MARKERS_DN 13892All SZGR genes in this pathway
YOSHIMURA_MAPK8_TARGETS_UP 1305895All SZGR genes in this pathway
MEISSNER_BRAIN_HCP_WITH_H3K4ME3_AND_H3K27ME3 1069729All SZGR genes in this pathway
KARLSSON_TGFB1_TARGETS_DN 207139All SZGR genes in this pathway
KIM_BIPOLAR_DISORDER_OLIGODENDROCYTE_DENSITY_CORR_DN 8859All SZGR genes in this pathway
JOHNSTONE_PARVB_TARGETS_2_DN 336211All SZGR genes in this pathway
PASINI_SUZ12_TARGETS_DN 315215All SZGR genes in this pathway
WAKABAYASHI_ADIPOGENESIS_PPARG_RXRA_BOUND_8D 882506All SZGR genes in this pathway
DURAND_STROMA_S_UP 297194All SZGR genes in this pathway
ZWANG_TRANSIENTLY_UP_BY_1ST_EGF_PULSE_ONLY 1839928All SZGR genes in this pathway


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