Gene Page: FCGR2A

Summary
GeneID  2212
Symbol  FCGR2A
Synonyms  CD32|CD32A|CDw32|FCG2|FCGR2|FCGR2A1|FcGR|IGFR2|MGC23887|MGC30032
Description  Fc fragment of IgG, low affinity IIa, receptor (CD32)
See related  HGNC:3616|MIM:146790|Ensembl:ENSG00000143226|HPRD:00906|
Locus tag  RP11-5K23.6
Gene type  protein-coding
Map location  1q23
 
Gene in Data Sources
Gene set name Method of gene set Evidence Info
GSMA_IIAgenome scan meta-analysis (All samples)Psr: 0.00814 
 
General Gene Expression (microarray) ?
 
Gene Expression in Brain Regions (new)
 
Top co-expressed genes in Brain Regions (new)
GenePearson's Correlation Spearman's Correlation
Top 10 positively co-expressed genes
Top 10 negatively co-expressed genes
Gene Ontology
Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0004872receptor activityIEA-
GO:0005515protein bindingIPI17785206 
GO:0019864IgG bindingIEA-
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0005634nucleusIDA18029348 
GO:0005730nucleolusIDA18029348 
GO:0005737cytoplasmIDA18029348 
GO:0016021integral to membraneIEA-
GO:0005886plasma membraneNAS2139735 
 
Protein-protein InteractionsShown by network
InteractorsAliases BOfficial full name BExperimentalSourcePubMed ID
BLKMGC10442B lymphoid tyrosine kinase-HPRD8756631 
CRPMGC149895 | MGC88244 | PTX1C-reactive protein, pentraxin-related-HPRD,BioGRID10675363 
HCKJTK9hemopoietic cell kinase-HPRD9268059 
LATLAT1 | pp36linker for activation of T cells-HPRD,BioGRID10781611 
LGALS3CBP35 | GAL3 | GALBP | GALIG | LGALS2 | MAC2lectin, galactoside-binding, soluble, 3-HPRD,BioGRID10704522 
LYNFLJ26625 | JTK8v-yes-1 Yamaguchi sarcoma viral related oncogene homologAffinity Capture-WesternBioGRID9268059 
PIK3R1GRB1 | p85 | p85-ALPHAphosphoinositide-3-kinase, regulatory subunit 1 (alpha)-HPRD,BioGRID8631888 
SHC1FLJ26504 | SHC | SHCASHC (Src homology 2 domain containing) transforming protein 1-HPRD,BioGRID8940017 |10382761 
SYKDKFZp313N1010 | FLJ25043 | FLJ37489spleen tyrosine kinaseReconstituted ComplexBioGRID9268059 
 
Pathway annotation
Pathway namePathway size# SZGR genes in pathwayInfo
KEGG_FC_GAMMA_R_MEDIATED_PHAGOCYTOSIS 9771All SZGR genes in this pathway
KEGG_LEISHMANIA_INFECTION 7256All SZGR genes in this pathway
KEGG_SYSTEMIC_LUPUS_ERYTHEMATOSUS 140100All SZGR genes in this pathway
PID_PTP1B_PATHWAY 5240All SZGR genes in this pathway
PID_INTEGRIN2_PATHWAY 2918All SZGR genes in this pathway
SCHUETZ_BREAST_CANCER_DUCTAL_INVASIVE_UP 351230All SZGR genes in this pathway
SENGUPTA_NASOPHARYNGEAL_CARCINOMA_UP 294178All SZGR genes in this pathway
FULCHER_INFLAMMATORY_RESPONSE_LECTIN_VS_LPS_UP 579346All SZGR genes in this pathway
DIAZ_CHRONIC_MEYLOGENOUS_LEUKEMIA_UP 1382904All SZGR genes in this pathway
SMIRNOV_CIRCULATING_ENDOTHELIOCYTES_IN_CANCER_UP 158103All SZGR genes in this pathway
MULLIGHAN_MLL_SIGNATURE_1_UP 380236All SZGR genes in this pathway
TONKS_TARGETS_OF_RUNX1_RUNX1T1_FUSION_HSC_DN 187115All SZGR genes in this pathway
JAATINEN_HEMATOPOIETIC_STEM_CELL_DN 226132All SZGR genes in this pathway
DODD_NASOPHARYNGEAL_CARCINOMA_DN 1375806All SZGR genes in this pathway
DELYS_THYROID_CANCER_UP 443294All SZGR genes in this pathway
SCHLOSSER_SERUM_RESPONSE_DN 712443All SZGR genes in this pathway
OKUMURA_INFLAMMATORY_RESPONSE_LPS 183115All SZGR genes in this pathway
BYSTRYKH_HEMATOPOIESIS_STEM_CELL_QTL_TRANS 882572All SZGR genes in this pathway
BROWN_MYELOID_CELL_DEVELOPMENT_UP 165100All SZGR genes in this pathway
NADLER_OBESITY_UP 6134All SZGR genes in this pathway
ADDYA_ERYTHROID_DIFFERENTIATION_BY_HEMIN 7347All SZGR genes in this pathway
LENAOUR_DENDRITIC_CELL_MATURATION_UP 11484All SZGR genes in this pathway
LENAOUR_DENDRITIC_CELL_MATURATION_DN 12890All SZGR genes in this pathway
LIAN_LIPA_TARGETS_6M 7447All SZGR genes in this pathway
MCDOWELL_ACUTE_LUNG_INJURY_UP 4529All SZGR genes in this pathway
LIAN_LIPA_TARGETS_3M 5936All SZGR genes in this pathway
CHEN_ETV5_TARGETS_SERTOLI 2010All SZGR genes in this pathway
MCLACHLAN_DENTAL_CARIES_DN 245144All SZGR genes in this pathway
VISALA_RESPONSE_TO_HEAT_SHOCK_AND_AGING_DN 1412All SZGR genes in this pathway
MCLACHLAN_DENTAL_CARIES_UP 253147All SZGR genes in this pathway
GAVIN_FOXP3_TARGETS_CLUSTER_P2 7955All SZGR genes in this pathway
MARSON_BOUND_BY_FOXP3_UNSTIMULATED 1229713All SZGR genes in this pathway
ACEVEDO_METHYLATED_IN_LIVER_CANCER_DN 940425All SZGR genes in this pathway
MARTINELLI_IMMATURE_NEUTROPHIL_DN 139All SZGR genes in this pathway
SWEET_KRAS_ONCOGENIC_SIGNATURE 8956All SZGR genes in this pathway
HOFFMANN_SMALL_PRE_BII_TO_IMMATURE_B_LYMPHOCYTE_DN 5033All SZGR genes in this pathway
CHEN_METABOLIC_SYNDROM_NETWORK 1210725All SZGR genes in this pathway
POOLA_INVASIVE_BREAST_CANCER_UP 288168All SZGR genes in this pathway
HOSHIDA_LIVER_CANCER_SUBCLASS_S1 237159All SZGR genes in this pathway
LI_INDUCED_T_TO_NATURAL_KILLER_UP 307182All SZGR genes in this pathway
VERHAAK_GLIOBLASTOMA_MESENCHYMAL 216130All SZGR genes in this pathway
DEMAGALHAES_AGING_UP 5539All SZGR genes in this pathway
CHYLA_CBFA2T3_TARGETS_UP 387225All SZGR genes in this pathway
WIERENGA_STAT5A_TARGETS_UP 217131All SZGR genes in this pathway
PILON_KLF1_TARGETS_DN 19721213All SZGR genes in this pathway
KIM_GLIS2_TARGETS_UP 8461All SZGR genes in this pathway
HUANG_GATA2_TARGETS_UP 14996All SZGR genes in this pathway
ALTEMEIER_RESPONSE_TO_LPS_WITH_MECHANICAL_VENTILATION 12881All SZGR genes in this pathway


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