Gene Page: PDXDC1

Summary
GeneID  23042
Symbol  PDXDC1
Synonyms  KIAA0251|LP8165
Description  pyridoxal-dependent decarboxylase domain containing 1
See related  HGNC:28995|Ensembl:ENSG00000179889|HPRD:13789|
Locus tag  -
Gene type  protein-coding
Map location  16p13.11
 
Gene in Data Sources
Gene set name Method of gene set Evidence Info
GSMA_IIEgenome scan meta-analysis (European-ancestry samples)Psr: 0.01775 
 
General Gene Expression (microarray) ?
 
Gene Expression in Brain Regions (new)
 
Top co-expressed genes in Brain Regions (new)
GenePearson's Correlation Spearman's Correlation
Top 10 positively co-expressed genes
HEATR5B0.950.97
KIF2A0.940.96
USP150.940.95
EHBP10.930.95
WDR470.930.96
PAPD50.930.95
CLASP20.930.95
RUFY30.920.96
AASDHPPT0.920.94
ARFGEF10.920.94
Top 10 negatively co-expressed genes
FXYD1-0.77-0.85
AF347015.31-0.77-0.85
MT-CO2-0.76-0.86
HSD17B14-0.76-0.82
AF347015.33-0.75-0.82
TSC22D4-0.75-0.82
HIGD1B-0.74-0.86
IFI27-0.74-0.84
METRN-0.74-0.87
AF347015.8-0.73-0.84
Gene Ontology
Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0005515protein bindingIPI17353931 
GO:0016829lyase activityIEA-
GO:0016831carboxy-lyase activityIEA-
GO:0030170pyridoxal phosphate bindingIEA-
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0019752carboxylic acid metabolic processIEA-
 
InteractionsShown by Network
InteractorsAliases BOfficial full name BExperimentalSourcePubMed ID
BCAP29BAP29 | DKFZp686M2086B-cell receptor-associated protein 29-HPRD11591653 
GIPC1C19orf3 | GIPC | GLUT1CBP | Hs.6454 | IIP-1 | MGC15889 | MGC3774 | NIP | RGS19IP1 | SEMCAP | SYNECTIIN | SYNECTIN | TIP-2GIPC PDZ domain containing family, member 1Affinity Capture-MSBioGRID17353931 
PHB2BAP | BCAP37 | Bap37 | MGC117268 | PNAS-141 | REA | p22prohibitin 2Affinity Capture-MSBioGRID17353931 
PHLDA3TIH1pleckstrin homology-like domain, family A, member 3Affinity Capture-MSBioGRID17353931 
 
Pathway annotation
Pathway namePathway size# SZGR genes in pathwayInfo
WATANABE_RECTAL_CANCER_RADIOTHERAPY_RESPONSIVE_UP 10867All SZGR genes in this pathway
FULCHER_INFLAMMATORY_RESPONSE_LECTIN_VS_LPS_DN 463290All SZGR genes in this pathway
CHARAFE_BREAST_CANCER_LUMINAL_VS_MESENCHYMAL_UP 450256All SZGR genes in this pathway
LINDGREN_BLADDER_CANCER_CLUSTER_1_DN 378231All SZGR genes in this pathway
DARWICHE_SKIN_TUMOR_PROMOTER_DN 185115All SZGR genes in this pathway
DARWICHE_PAPILLOMA_RISK_LOW_UP 162104All SZGR genes in this pathway
DARWICHE_PAPILLOMA_RISK_HIGH_DN 180110All SZGR genes in this pathway
DARWICHE_SQUAMOUS_CELL_CARCINOMA_DN 181107All SZGR genes in this pathway
RICKMAN_METASTASIS_UP 344180All SZGR genes in this pathway
STARK_PREFRONTAL_CORTEX_22Q11_DELETION_DN 517309All SZGR genes in this pathway
BYSTRYKH_HEMATOPOIESIS_STEM_CELL_QTL_CIS 12877All SZGR genes in this pathway
CHESLER_BRAIN_QTL_CIS 7551All SZGR genes in this pathway
BYSTRYKH_HEMATOPOIESIS_STEM_CELL_AND_BRAIN_QTL_TRANS 185114All SZGR genes in this pathway
BYSTRYKH_HEMATOPOIESIS_STEM_CELL_AND_BRAIN_QTL_CIS 6538All SZGR genes in this pathway
CHESLER_BRAIN_HIGHEST_GENETIC_VARIANCE 3721All SZGR genes in this pathway
BYSTRYKH_HEMATOPOIESIS_STEM_CELL_QTL_TRANS 882572All SZGR genes in this pathway
FLECHNER_BIOPSY_KIDNEY_TRANSPLANT_REJECTED_VS_OK_DN 546351All SZGR genes in this pathway
KUMAR_TARGETS_OF_MLL_AF9_FUSION 405264All SZGR genes in this pathway
CREIGHTON_ENDOCRINE_THERAPY_RESISTANCE_3 720440All SZGR genes in this pathway
COATES_MACROPHAGE_M1_VS_M2_DN 7844All SZGR genes in this pathway
MASSARWEH_TAMOXIFEN_RESISTANCE_UP 578341All SZGR genes in this pathway
YOKOE_CANCER_TESTIS_ANTIGENS 3822All SZGR genes in this pathway
CAMPS_COLON_CANCER_COPY_NUMBER_DN 7434All SZGR genes in this pathway
TOYOTA_TARGETS_OF_MIR34B_AND_MIR34C 463262All SZGR genes in this pathway
GRADE_COLON_CANCER_UP 871505All SZGR genes in this pathway
BREDEMEYER_RAG_SIGNALING_NOT_VIA_ATM_DN 5734All SZGR genes in this pathway
BREDEMEYER_RAG_SIGNALING_VIA_ATM_NOT_VIA_NFKB_DN 3823All SZGR genes in this pathway
KYNG_WERNER_SYNDROM_AND_NORMAL_AGING_DN 225124All SZGR genes in this pathway
KIM_BIPOLAR_DISORDER_OLIGODENDROCYTE_DENSITY_CORR_UP 682440All SZGR genes in this pathway
BRUINS_UVC_RESPONSE_VIA_TP53_GROUP_A 898516All SZGR genes in this pathway
miRNA Targets ?
miRNA familyTarget positionmiRNA IDmiRNA seq
UTR startUTR endMatch method
miR-182158315901A,m8hsa-miR-182UUUGGCAAUGGUAGAACUCACA
miR-96158415901Ahsa-miR-96brainUUUGGCACUAGCACAUUUUUGC
  • SZ: miRNAs which differentially expressed in brain cortex of schizophrenia patients comparing with control samples using microarray. Click here to see the list of SZ related miRNAs.
  • Brain: miRNAs which are expressed in brain based on miRNA microarray expression studies. Click here to see the list of brain related miRNAs.


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