Gene Page: METAP1D
Summary ?
| GeneID | 254042 |
| Symbol | METAP1D |
| Synonyms | MAP 1D|MAP1D|MetAP 1D|Metap1l |
| Description | methionyl aminopeptidase type 1D (mitochondrial) |
| Reference | MIM:610267|HGNC:HGNC:32583|Ensembl:ENSG00000172878|HPRD:17462|Vega:OTTHUMG00000132283 |
| Gene type | protein-coding |
| Map location | 2q31.1 |
| Pascal p-value | 9.709E-6 |
| eGene | Anterior cingulate cortex BA24 |
Gene in Data Sources
| Gene set name | Method of gene set | Description | Info |
|---|---|---|---|
| CV:PGCnp | Genome-wide Association Study | GWAS |
Section I. Genetics and epigenetics annotation
eQTL annotation
| SNP ID | Chromosome | Position | eGene | Gene Entrez ID | pvalue | qvalue | TSS distance | eQTL type |
|---|---|---|---|---|---|---|---|---|
| rs979956 | 2 | 172528095 | METAP1D | ENSG00000172878.9 | 1.60471E-6 | 0.04 | -358608 | gtex_brain_ba24 |
| rs979957 | 2 | 172528159 | METAP1D | ENSG00000172878.9 | 1.59742E-6 | 0.04 | -358544 | gtex_brain_ba24 |
| rs11675891 | 2 | 172550440 | METAP1D | ENSG00000172878.9 | 2.94355E-6 | 0.04 | -336263 | gtex_brain_ba24 |
| rs397698023 | 2 | 172561631 | METAP1D | ENSG00000172878.9 | 2.94355E-6 | 0.04 | -325072 | gtex_brain_ba24 |
| rs74268271 | 2 | 172582344 | METAP1D | ENSG00000172878.9 | 3.38336E-6 | 0.04 | -304359 | gtex_brain_ba24 |
| rs13016580 | 2 | 172646528 | METAP1D | ENSG00000172878.9 | 2.94355E-6 | 0.04 | -240175 | gtex_brain_ba24 |
| rs34221876 | 2 | 172664191 | METAP1D | ENSG00000172878.9 | 2.94572E-6 | 0.04 | -222512 | gtex_brain_ba24 |
| rs200151513 | 2 | 172881237 | METAP1D | ENSG00000172878.9 | 1.88129E-6 | 0.04 | -5466 | gtex_brain_ba24 |
Section II. Transcriptome annotation
General gene expression (GTEx)
Gene expression of temporal and spatial changes (BrainSpan)
Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes the lower 25% and upper 25% of the expression distribution.
No co-expressed genes in brain regions
Section V. Pathway annotation
| Pathway name | Pathway size | # SZGR 2.0 genes in pathway | Info |
|---|---|---|---|
| NUYTTEN NIPP1 TARGETS UP | 769 | 437 | All SZGR 2.0 genes in this pathway |
| JOHNSTONE PARVB TARGETS 3 DN | 918 | 550 | All SZGR 2.0 genes in this pathway |