Gene Page: GK2
Summary ?
GeneID | 2712 |
Symbol | GK2 |
Synonyms | GKP2|GKTA |
Description | glycerol kinase 2 |
Reference | MIM:600148|HGNC:HGNC:4291|Ensembl:ENSG00000196475|HPRD:15966|Vega:OTTHUMG00000130199 |
Gene type | protein-coding |
Map location | 4q13 |
Pascal p-value | 0.017 |
Gene in Data Sources
Gene set name | Method of gene set | Description | Info |
---|---|---|---|
CV:PGCnp | Genome-wide Association Study | GWAS |
Section I. Genetics and epigenetics annotation
Section II. Transcriptome annotation
General gene expression (GTEx)
Gene expression of temporal and spatial changes (BrainSpan)
Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes the lower 25% and upper 25% of the expression distribution.
Top co-expressed genes in brain regions
Top 10 positively co-expressed genes | ||
Gene | Pearson's Correlation | Spearman's Correlation |
ENPP4 | 0.89 | 0.90 |
ERMP1 | 0.88 | 0.85 |
CLIP4 | 0.87 | 0.87 |
SBDS | 0.87 | 0.86 |
EDIL3 | 0.86 | 0.89 |
SLC22A15 | 0.86 | 0.84 |
ENDOD1 | 0.86 | 0.84 |
LIPA | 0.86 | 0.88 |
LAMP2 | 0.85 | 0.87 |
DEPDC6 | 0.85 | 0.80 |
Top 10 negatively co-expressed genes | ||
Gene | Pearson's Correlation | Spearman's Correlation |
BCL7C | -0.52 | -0.63 |
RPL36 | -0.48 | -0.57 |
RPL35 | -0.47 | -0.55 |
NME4 | -0.46 | -0.61 |
RPL28 | -0.46 | -0.59 |
RPS21 | -0.46 | -0.56 |
RPLP1 | -0.45 | -0.53 |
WDR86 | -0.45 | -0.44 |
AC006276.2 | -0.45 | -0.49 |
SIGIRR | -0.44 | -0.55 |
Section V. Pathway annotation
Pathway name | Pathway size | # SZGR 2.0 genes in pathway | Info |
---|---|---|---|
KEGG GLYCEROLIPID METABOLISM | 49 | 26 | All SZGR 2.0 genes in this pathway |
KEGG PPAR SIGNALING PATHWAY | 69 | 47 | All SZGR 2.0 genes in this pathway |
AMUNDSON RESPONSE TO ARSENITE | 217 | 143 | All SZGR 2.0 genes in this pathway |
AFFAR YY1 TARGETS DN | 234 | 137 | All SZGR 2.0 genes in this pathway |
SU TESTIS | 76 | 53 | All SZGR 2.0 genes in this pathway |
ACEVEDO METHYLATED IN LIVER CANCER DN | 940 | 425 | All SZGR 2.0 genes in this pathway |