Gene Page: CCDC66
Summary ?
| GeneID | 285331 |
| Symbol | CCDC66 |
| Synonyms | - |
| Description | coiled-coil domain containing 66 |
| Reference | HGNC:HGNC:27709|Ensembl:ENSG00000180376|HPRD:14569|Vega:OTTHUMG00000155748 |
| Gene type | protein-coding |
| Map location | 3p14.3 |
| Pascal p-value | 0.047 |
| eGene | Caudate basal ganglia Cerebellum Cortex Frontal Cortex BA9 Hippocampus Hypothalamus Nucleus accumbens basal ganglia Putamen basal ganglia Myers' cis & trans Meta |
Gene in Data Sources
| Gene set name | Method of gene set | Description | Info |
|---|---|---|---|
| CV:GWASdb | Genome-wide Association Studies | GWASdb records for schizophrenia | |
| CV:PGCnp | Genome-wide Association Study | GWAS |
Section I. Genetics and epigenetics annotation
eQTL annotation
| SNP ID | Chromosome | Position | eGene | Gene Entrez ID | pvalue | qvalue | TSS distance | eQTL type |
|---|---|---|---|---|---|---|---|---|
| rs7689670 | chr4 | 77455539 | CCDC66 | 285331 | 0.19 | trans | ||
| rs111685858 | 3 | 56526844 | CCDC66 | ENSG00000180376.12 | 1.085E-6 | 0 | -64345 | gtex_brain_putamen_basal |
| rs73079863 | 3 | 56561356 | CCDC66 | ENSG00000180376.12 | 1.063E-7 | 0 | -29833 | gtex_brain_putamen_basal |
| rs112312748 | 3 | 56578372 | CCDC66 | ENSG00000180376.12 | 8.422E-9 | 0 | -12817 | gtex_brain_putamen_basal |
| rs6791987 | 3 | 56579538 | CCDC66 | ENSG00000180376.12 | 1.208E-7 | 0 | -11651 | gtex_brain_putamen_basal |
| rs73079883 | 3 | 56588311 | CCDC66 | ENSG00000180376.12 | 2.162E-7 | 0 | -2878 | gtex_brain_putamen_basal |
| rs73079884 | 3 | 56588451 | CCDC66 | ENSG00000180376.12 | 2.162E-7 | 0 | -2738 | gtex_brain_putamen_basal |
| rs79600744 | 3 | 56591059 | CCDC66 | ENSG00000180376.12 | 2.163E-7 | 0 | -130 | gtex_brain_putamen_basal |
| rs73079891 | 3 | 56591178 | CCDC66 | ENSG00000180376.12 | 2.163E-7 | 0 | -11 | gtex_brain_putamen_basal |
| rs73079894 | 3 | 56591508 | CCDC66 | ENSG00000180376.12 | 2.163E-7 | 0 | 319 | gtex_brain_putamen_basal |
| rs111349193 | 3 | 56597255 | CCDC66 | ENSG00000180376.12 | 2.155E-7 | 0 | 6066 | gtex_brain_putamen_basal |
| rs6792321 | 3 | 56597470 | CCDC66 | ENSG00000180376.12 | 2.163E-7 | 0 | 6281 | gtex_brain_putamen_basal |
| rs6781293 | 3 | 56597688 | CCDC66 | ENSG00000180376.12 | 2.163E-7 | 0 | 6499 | gtex_brain_putamen_basal |
| rs111827080 | 3 | 56599758 | CCDC66 | ENSG00000180376.12 | 1.736E-7 | 0 | 8569 | gtex_brain_putamen_basal |
| rs56204053 | 3 | 56621847 | CCDC66 | ENSG00000180376.12 | 2.126E-6 | 0 | 30658 | gtex_brain_putamen_basal |
| rs2317249 | 3 | 56753003 | CCDC66 | ENSG00000180376.12 | 2.494E-7 | 0 | 161814 | gtex_brain_putamen_basal |
| rs6445820 | 3 | 56753689 | CCDC66 | ENSG00000180376.12 | 3.036E-6 | 0 | 162500 | gtex_brain_putamen_basal |
Section II. Transcriptome annotation
General gene expression (GTEx)
Gene expression of temporal and spatial changes (BrainSpan)
Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes the lower 25% and upper 25% of the expression distribution.
No co-expressed genes in brain regions
Section V. Pathway annotation
| Pathway name | Pathway size | # SZGR 2.0 genes in pathway | Info |
|---|---|---|---|
| LASTOWSKA NEUROBLASTOMA COPY NUMBER DN | 800 | 473 | All SZGR 2.0 genes in this pathway |