Gene Page: NKX6-1

Summary
GeneID  4825
Symbol  NKX6-1
Synonyms  NKX6.1|NKX6A
Description  NK6 homeobox 1
See related  HGNC:7839|MIM:602563|Ensembl:ENSG00000163623|HPRD:09092|
Locus tag  -
Gene type  protein-coding
Map location  4q21.2-q22
 
Gene in Data Sources
Gene set name Method of gene set Evidence Info
GO_AnnotationMapping neuro-related keywords to Gene Ontology annotationsHits with neuro-related keywords: 2 
 
General Gene Expression (microarray) ?
 
Gene Expression in Brain Regions (new)
 
Top co-expressed genes in Brain Regions (new)
GenePearson's Correlation Spearman's Correlation
Top 10 positively co-expressed genes
RP4-788L13.10.750.80
CRY20.740.78
PRICKLE20.710.77
SCN3B0.690.80
PCDHA50.690.77
GABRA50.680.71
SLC8A20.680.77
LINGO10.670.75
WSB20.670.78
DLG20.670.74
Top 10 negatively co-expressed genes
AL139819.3-0.43-0.52
AF347015.26-0.42-0.47
AP002478.3-0.42-0.55
AF347015.33-0.41-0.48
AF347015.21-0.41-0.47
C11orf67-0.41-0.55
MT-CO2-0.41-0.50
AF347015.18-0.40-0.53
AF347015.8-0.40-0.49
S100A1-0.40-0.39
Gene Ontology
Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0003700transcription factor activityIEA-
GO:0043565sequence-specific DNA bindingIEA-
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0045687positive regulation of glial cell differentiationIEAGlial (GO term level: 11)-
GO:0045686negative regulation of glial cell differentiationIEAGlial (GO term level: 11)-
GO:0006355regulation of transcription, DNA-dependentIEA-
GO:0009887organ morphogenesisTAS10567713 
GO:0007275multicellular organismal developmentIEA-
GO:0030154cell differentiationIEA-
GO:0031018endocrine pancreas developmentIEA-
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0005634nucleusIEA-
 
Pathway annotation
Pathway namePathway size# SZGR genes in pathwayInfo
KEGG_MATURITY_ONSET_DIABETES_OF_THE_YOUNG 2519All SZGR genes in this pathway
REACTOME_DEVELOPMENTAL_BIOLOGY 396292All SZGR genes in this pathway
REACTOME_REGULATION_OF_BETA_CELL_DEVELOPMENT 3023All SZGR genes in this pathway
REACTOME_REGULATION_OF_GENE_EXPRESSION_IN_BETA_CELLS 2015All SZGR genes in this pathway
BENPORATH_SUZ12_TARGETS 1038678All SZGR genes in this pathway
BENPORATH_EED_TARGETS 1062725All SZGR genes in this pathway
BENPORATH_ES_WITH_H3K27ME3 1118744All SZGR genes in this pathway
BENPORATH_PRC2_TARGETS 652441All SZGR genes in this pathway
TAYLOR_METHYLATED_IN_ACUTE_LYMPHOBLASTIC_LEUKEMIA 7752All SZGR genes in this pathway
ZHOU_PANCREATIC_ENDOCRINE_PROGENITOR 1411All SZGR genes in this pathway
ZHOU_PANCREATIC_BETA_CELL 119All SZGR genes in this pathway
MEISSNER_BRAIN_HCP_WITH_H3K27ME3 269159All SZGR genes in this pathway
MEISSNER_NPC_HCP_WITH_H3K4ME2_AND_H3K27ME3 349234All SZGR genes in this pathway
MIKKELSEN_MCV6_HCP_WITH_H3K27ME3 435318All SZGR genes in this pathway
MIKKELSEN_NPC_HCP_WITH_H3K27ME3 341243All SZGR genes in this pathway
MIKKELSEN_MEF_HCP_WITH_H3K27ME3 590403All SZGR genes in this pathway
MARTENS_TRETINOIN_RESPONSE_UP 857456All SZGR genes in this pathway
WANG_MLL_TARGETS 289188All SZGR genes in this pathway
ROLEF_GLIS3_TARGETS 3729All SZGR genes in this pathway


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