Gene Page: NRAP
Summary ?
| GeneID | 4892 |
| Symbol | NRAP |
| Synonyms | N-RAP |
| Description | nebulin related anchoring protein |
| Reference | MIM:602873|HGNC:HGNC:7988|Ensembl:ENSG00000197893|HPRD:04189|Vega:OTTHUMG00000019072 |
| Gene type | protein-coding |
| Map location | 10q24-q26 |
| Pascal p-value | 0.028 |
Gene in Data Sources
| Gene set name | Method of gene set | Description | Info |
|---|---|---|---|
| CV:PGCnp | Genome-wide Association Study | GWAS |
Section I. Genetics and epigenetics annotation
Section II. Transcriptome annotation
General gene expression (GTEx)
Gene expression of temporal and spatial changes (BrainSpan)
Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes the lower 25% and upper 25% of the expression distribution.
Top co-expressed genes in brain regions
| Top 10 positively co-expressed genes | ||
| Gene | Pearson's Correlation | Spearman's Correlation |
| GPRIN1 | 0.89 | 0.95 |
| HECTD3 | 0.88 | 0.93 |
| KIAA1543 | 0.88 | 0.94 |
| TSPAN14 | 0.87 | 0.92 |
| TSKU | 0.87 | 0.81 |
| MARCH4 | 0.86 | 0.93 |
| KDM2B | 0.85 | 0.91 |
| GMIP | 0.85 | 0.92 |
| JUP | 0.85 | 0.85 |
| ANKRD13B | 0.85 | 0.90 |
| Top 10 negatively co-expressed genes | ||
| Gene | Pearson's Correlation | Spearman's Correlation |
| HLA-F | -0.64 | -0.76 |
| S100B | -0.63 | -0.83 |
| AIFM3 | -0.62 | -0.75 |
| C5orf53 | -0.62 | -0.71 |
| HEPN1 | -0.61 | -0.73 |
| ACOT13 | -0.61 | -0.64 |
| AF347015.27 | -0.61 | -0.84 |
| ALDOC | -0.61 | -0.67 |
| AP003117.1 | -0.61 | -0.65 |
| AF347015.31 | -0.61 | -0.84 |
Section V. Pathway annotation
| Pathway name | Pathway size | # SZGR 2.0 genes in pathway | Info |
|---|---|---|---|
| THUM SYSTOLIC HEART FAILURE UP | 423 | 283 | All SZGR 2.0 genes in this pathway |
| ZHOU INFLAMMATORY RESPONSE FIMA UP | 544 | 308 | All SZGR 2.0 genes in this pathway |
| ZHOU INFLAMMATORY RESPONSE LPS UP | 431 | 237 | All SZGR 2.0 genes in this pathway |
| HAMAI APOPTOSIS VIA TRAIL DN | 186 | 107 | All SZGR 2.0 genes in this pathway |
| MARIADASON REGULATED BY HISTONE ACETYLATION DN | 54 | 30 | All SZGR 2.0 genes in this pathway |
| ACEVEDO LIVER CANCER WITH H3K9ME3 UP | 141 | 75 | All SZGR 2.0 genes in this pathway |
| ACEVEDO METHYLATED IN LIVER CANCER DN | 940 | 425 | All SZGR 2.0 genes in this pathway |
| ACEVEDO FGFR1 TARGETS IN PROSTATE CANCER MODEL DN | 308 | 187 | All SZGR 2.0 genes in this pathway |