SZGR2

Summary ?

GeneID	51534
Symbol	VTA1
Synonyms	C6orf55\|DRG-1\|DRG1\|HSPC228\|LIP5\|My012\|SBP1
Description	vesicle (multivesicular body) trafficking 1
Reference	MIM:610902\|HGNC:HGNC:20954\|Ensembl:ENSG00000009844\|HPRD:09855\|
Gene type	protein-coding
Map location	6q24.1
Pascal p-value	0.274
Sherlock p-value	0.856
Fetal beta	0.625
eGene	Myers' cis & trans Meta

Gene in Data Sources

Gene set name	Method of gene set	Description	Info
CV:GWASdb	Genome-wide Association Studies	GWASdb records for schizophrenia
CV:PGCnp	Genome-wide Association Study	GWAS

Section I. Genetics and epigenetics annotation

eQTL annotation

SNP ID	Chromosome	Position	eGene	Gene Entrez ID	pvalue	qvalue	TSS distance	eQTL type
rs10994209	chr10	61877705	VTA1	51534		0.05		trans

Section II. Transcriptome annotation

General gene expression (GTEx)

Gene expression during devlopment (BrainCloud)

Footnote:
A total of 269 time points ploted, with n=38 fetal samples (x=1:38). Each triangle represents one time point.

Gene expression of temporal and spatial changes (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes the lower 25% and upper 25% of the expression distribution.

No co-expressed genes in brain regions

Section IV. Protein-protein interaction annotation

Interactors	Aliases B	Official full name B	Experimental	Source	PubMed ID
CBS	HIP4	cystathionine-beta-synthase	Two-hybrid	BioGRID	16189514
CDK4	CMM3 \| MGC14458 \| PSK-J3	cyclin-dependent kinase 4	Two-hybrid	BioGRID	16189514
DPPA2	PESCRG1	developmental pluripotency associated 2	Two-hybrid	BioGRID	16189514
KCTD13	FKSG86 \| PDIP1 \| POLDIP1	potassium channel tetramerisation domain containing 13	Two-hybrid	BioGRID	16189514
KLHL12	C3IP1 \| DKIR \| FLJ27152	kelch-like 12 (Drosophila)	Two-hybrid	BioGRID	16189514
LYST	CHS \| CHS1	lysosomal trafficking regulator	Two-hybrid	BioGRID	11984006
MAGEA11	MAGE-11 \| MAGE11 \| MAGEA-11 \| MGC10511	melanoma antigen family A, 11	Two-hybrid	BioGRID	16189514
MBIP	-	MAP3K12 binding inhibitory protein 1	Two-hybrid	BioGRID	16189514
NBR1	1A1-3B \| KIAA0049 \| M17S2 \| MIG19	neighbor of BRCA1 gene 1	Two-hybrid	BioGRID	16189514
NECAB2	EFCBP2	N-terminal EF-hand calcium binding protein 2	Two-hybrid	BioGRID	16189514
RABAC1	PRA1 \| PRAF1 \| YIP3	Rab acceptor 1 (prenylated)	Two-hybrid	BioGRID	16189514
RPIA	RPI	ribose 5-phosphate isomerase A	Two-hybrid	BioGRID	16189514
SSSCA1	p27	Sjogren syndrome/scleroderma autoantigen 1	Two-hybrid	BioGRID	16189514
ZBTB16	PLZF \| ZNF145	zinc finger and BTB domain containing 16	Two-hybrid	BioGRID	16189514

Section V. Pathway annotation

Pathway name	Pathway size	# SZGR 2.0 genes in pathway	Info
KEGG ENDOCYTOSIS	183	132	All SZGR 2.0 genes in this pathway
REACTOME MEMBRANE TRAFFICKING	129	74	All SZGR 2.0 genes in this pathway
REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT	27	15	All SZGR 2.0 genes in this pathway
OSMAN BLADDER CANCER UP	404	246	All SZGR 2.0 genes in this pathway
RODRIGUES THYROID CARCINOMA ANAPLASTIC UP	722	443	All SZGR 2.0 genes in this pathway
GAUSSMANN MLL AF4 FUSION TARGETS G UP	238	135	All SZGR 2.0 genes in this pathway
BENPORATH CYCLING GENES	648	385	All SZGR 2.0 genes in this pathway
KUMAR TARGETS OF MLL AF9 FUSION	405	264	All SZGR 2.0 genes in this pathway
IVANOVA HEMATOPOIESIS STEM CELL AND PROGENITOR	681	420	All SZGR 2.0 genes in this pathway
MARSON BOUND BY FOXP3 UNSTIMULATED	1229	713	All SZGR 2.0 genes in this pathway
ACEVEDO LIVER CANCER DN	540	340	All SZGR 2.0 genes in this pathway
CHANG CORE SERUM RESPONSE UP	212	128	All SZGR 2.0 genes in this pathway
WENDT COHESIN TARGETS UP	33	19	All SZGR 2.0 genes in this pathway
WHITFIELD CELL CYCLE G2	182	102	All SZGR 2.0 genes in this pathway
BRUINS UVC RESPONSE LATE	1137	655	All SZGR 2.0 genes in this pathway

Gene Page: VTA1