Gene Page: PIK3CA

Summary
GeneID  5290
Symbol  PIK3CA
Synonyms  MGC142161|MGC142163|PI3K|p110-alpha
Description  phosphoinositide-3-kinase, catalytic, alpha polypeptide
See related  HGNC:8975|MIM:171834|Ensembl:ENSG00000121879|HPRD:01382|
Locus tag  -
Gene type  protein-coding
Map location  3q26.3
 
Gene in Data Sources
Gene set name Method of gene set Evidence Info
NetworkShortest path distance of core genes in the Human protein-protein interaction networkContribution to shortest path in PPI network: 0.2151 
 
General Gene Expression (microarray) ?
 
Gene Expression in Brain Regions (new)
 
Top co-expressed genes in Brain Regions (new)
GenePearson's Correlation Spearman's Correlation
Top 10 positively co-expressed genes
ADORA2B0.860.82
ACSF20.850.81
CST30.840.93
OAF0.840.82
TLCD10.840.92
CLDN100.820.91
BST20.820.84
ALDH1A10.810.84
IFI270.810.88
CXCL140.810.88
Top 10 negatively co-expressed genes
PARG-0.75-0.80
EIF4ENIF1-0.75-0.85
C6orf168-0.74-0.84
ADSS-0.73-0.77
CSRP2BP-0.73-0.76
CUL1-0.73-0.85
FBXW2-0.73-0.83
C4orf41-0.73-0.84
ZNF174-0.73-0.85
MCM3AP-0.73-0.88
Gene Ontology
Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0005515protein bindingIPI10490823 
GO:0004428inositol or phosphatidylinositol kinase activityIEA-
GO:0016773phosphotransferase activity, alcohol group as acceptorIEA-
GO:0016740transferase activityIEA-
GO:00163031-phosphatidylinositol-3-kinase activityIDA2174051 
GO:0046934phosphatidylinositol-4,5-bisphosphate 3-kinase activityEXP10648629 
GO:0046934phosphatidylinositol-4,5-bisphosphate 3-kinase activityIEA-
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0007165signal transductionIEA-
GO:0048015phosphoinositide-mediated signalingIEA-
GO:0046854phosphoinositide phosphorylationIEA-
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0005829cytosolEXP10648629 |12167717 |12660731 
GO:0005737cytoplasmIDA18029348 
GO:0005739mitochondrionIDA18029348 
GO:0005942phosphoinositide 3-kinase complexIEA-
 
Protein-protein InteractionsShown by network
InteractorsAliases BOfficial full name BExperimentalSourcePubMed ID
ADAP1CENTA1 | GCS1L | p42IP4ArfGAP with dual PH domains 1Biochemical Activity
Reconstituted Complex		BioGRID12893243 
APPL1APPL | DIP13alphaadaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1APPL interacts with p110-alpha.BIND10490823 
ARHGEF1GEF1 | LBCL2 | LSC | P115-RHOGEF | SUB1.5Rho guanine nucleotide exchange factor (GEF) 1Affinity Capture-WesternBioGRID12754211 
ATRFRP1 | MEC1 | SCKL | SCKL1ataxia telangiectasia and Rad3 relatedProtein-peptideBioGRID10608806 
CBLC-CBL | CBL2 | RNF55Cas-Br-M (murine) ecotropic retroviral transforming sequenceCo-purificationBioGRID8641358 
DGKZDAGK5 | DAGK6 | DGK-ZETA | hDGKzetadiacylglycerol kinase, zeta 104kDaAffinity Capture-Western
Biochemical Activity		BioGRID12890670 
GABRB1-gamma-aminobutyric acid (GABA) A receptor, beta 1-HPRD11606067 
GNAQG-ALPHA-q | GAQguanine nucleotide binding protein (G protein), q polypeptide-HPRD,BioGRID12704201 
GSNDKFZp313L0718gelsolin (amyloidosis, Finnish type)Affinity Capture-WesternBioGRID11577104 
HRASC-BAS/HAS | C-H-RAS | C-HA-RAS1 | CTLO | H-RASIDX | HAMSV | HRAS1 | K-RAS | N-RAS | RASH1v-Ha-ras Harvey rat sarcoma viral oncogene homolog-HPRD9150145 
Reconstituted Complex
Two-hybrid		BioGRID8665852 |10783161 
|14724584 
IRS1HIRS-1insulin receptor substrate 1Affinity Capture-WesternBioGRID16354680 
IRS4IRS-4 | PY160insulin receptor substrate 4-HPRD,BioGRID11912194 
KRASC-K-RAS | K-RAS2A | K-RAS2B | K-RAS4A | K-RAS4B | KI-RAS | KRAS1 | KRAS2 | NS3 | RASK2v-Ki-ras2 Kirsten rat sarcoma viral oncogene homologTwo-hybridBioGRID10783161 
LCKYT16 | p56lck | pp58lcklymphocyte-specific protein tyrosine kinase-HPRD,BioGRID8020561 
NOTCH1TAN1 | hN1Notch homolog 1, translocation-associated (Drosophila)Affinity Capture-WesternBioGRID14583609 
PIK3R1GRB1 | p85 | p85-ALPHAphosphoinositide-3-kinase, regulatory subunit 1 (alpha)Reconstituted ComplexBioGRID7929193 
PIK3R3DKFZp686P05226 | FLJ41892 | p55 | p55-GAMMAphosphoinositide-3-kinase, regulatory subunit 3 (gamma)-HPRD,BioGRID9415396 
RASD2MGC:4834 | Rhes | TEM2RASD family, member 2-HPRD,BioGRID14724584 
RASGRP3GRP3 | KIAA0846RAS guanyl releasing protein 3 (calcium and DAG-regulated)Biochemical ActivityBioGRID15213298 
SLC9A3R1EBP50 | NHERF | NHERF1 | NPHLOP2solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 1Reconstituted ComplexBioGRID12954600 
SLC9A3R2E3KARP | MGC104639 | NHE3RF2 | NHERF-2 | NHERF2 | OCTS2 | SIP-1 | SIP1 | TKA-1solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 2Reconstituted ComplexBioGRID12954600 
YWHAHYWHA1tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta polypeptideAffinity Capture-WesternBioGRID11969417 
YWHAQ14-3-3 | 1C5 | HS1tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptideReconstituted ComplexBioGRID8663231 
 
Pathway annotation
Pathway namePathway size# SZGR genes in pathwayInfo
KEGG_INOSITOL_PHOSPHATE_METABOLISM 5442All SZGR genes in this pathway
KEGG_ERBB_SIGNALING_PATHWAY 8771All SZGR genes in this pathway
KEGG_CHEMOKINE_SIGNALING_PATHWAY 190128All SZGR genes in this pathway
KEGG_PHOSPHATIDYLINOSITOL_SIGNALING_SYSTEM 7656All SZGR genes in this pathway
KEGG_MTOR_SIGNALING_PATHWAY 5240All SZGR genes in this pathway
KEGG_APOPTOSIS 8862All SZGR genes in this pathway
KEGG_VEGF_SIGNALING_PATHWAY 7653All SZGR genes in this pathway
KEGG_FOCAL_ADHESION 201138All SZGR genes in this pathway
KEGG_TOLL_LIKE_RECEPTOR_SIGNALING_PATHWAY 10288All SZGR genes in this pathway
KEGG_JAK_STAT_SIGNALING_PATHWAY 155105All SZGR genes in this pathway
KEGG_NATURAL_KILLER_CELL_MEDIATED_CYTOTOXICITY 13792All SZGR genes in this pathway
KEGG_T_CELL_RECEPTOR_SIGNALING_PATHWAY 10889All SZGR genes in this pathway
KEGG_B_CELL_RECEPTOR_SIGNALING_PATHWAY 7556All SZGR genes in this pathway
KEGG_FC_EPSILON_RI_SIGNALING_PATHWAY 7958All SZGR genes in this pathway
KEGG_FC_GAMMA_R_MEDIATED_PHAGOCYTOSIS 9771All SZGR genes in this pathway
KEGG_LEUKOCYTE_TRANSENDOTHELIAL_MIGRATION 11878All SZGR genes in this pathway
KEGG_NEUROTROPHIN_SIGNALING_PATHWAY 126103All SZGR genes in this pathway
KEGG_REGULATION_OF_ACTIN_CYTOSKELETON 216144All SZGR genes in this pathway
KEGG_INSULIN_SIGNALING_PATHWAY 137103All SZGR genes in this pathway
KEGG_PROGESTERONE_MEDIATED_OOCYTE_MATURATION 8659All SZGR genes in this pathway
KEGG_TYPE_II_DIABETES_MELLITUS 4741All SZGR genes in this pathway
KEGG_ALDOSTERONE_REGULATED_SODIUM_REABSORPTION 4229All SZGR genes in this pathway
KEGG_PATHWAYS_IN_CANCER 328259All SZGR genes in this pathway
KEGG_COLORECTAL_CANCER 6247All SZGR genes in this pathway
KEGG_RENAL_CELL_CARCINOMA 7060All SZGR genes in this pathway
KEGG_PANCREATIC_CANCER 7056All SZGR genes in this pathway
KEGG_ENDOMETRIAL_CANCER 5245All SZGR genes in this pathway
KEGG_GLIOMA 6556All SZGR genes in this pathway
KEGG_PROSTATE_CANCER 8975All SZGR genes in this pathway
KEGG_MELANOMA 7157All SZGR genes in this pathway
KEGG_CHRONIC_MYELOID_LEUKEMIA 7359All SZGR genes in this pathway
KEGG_ACUTE_MYELOID_LEUKEMIA 6047All SZGR genes in this pathway
KEGG_SMALL_CELL_LUNG_CANCER 8467All SZGR genes in this pathway
KEGG_NON_SMALL_CELL_LUNG_CANCER 5447All SZGR genes in this pathway
BIOCARTA_AKT_PATHWAY 2216All SZGR genes in this pathway
BIOCARTA_BCELLSURVIVAL_PATHWAY 1610All SZGR genes in this pathway
BIOCARTA_HDAC_PATHWAY 3225All SZGR genes in this pathway
BIOCARTA_GCR_PATHWAY 2217All SZGR genes in this pathway
BIOCARTA_CTCF_PATHWAY 2318All SZGR genes in this pathway
BIOCARTA_CXCR4_PATHWAY 2422All SZGR genes in this pathway
BIOCARTA_EGF_PATHWAY 3125All SZGR genes in this pathway
BIOCARTA_ECM_PATHWAY 2417All SZGR genes in this pathway
BIOCARTA_FCER1_PATHWAY 4130All SZGR genes in this pathway
BIOCARTA_GH_PATHWAY 2822All SZGR genes in this pathway
BIOCARTA_HCMV_PATHWAY 1716All SZGR genes in this pathway
BIOCARTA_IGF1_PATHWAY 2116All SZGR genes in this pathway
BIOCARTA_IL2RB_PATHWAY 3826All SZGR genes in this pathway
BIOCARTA_IL7_PATHWAY 1714All SZGR genes in this pathway
BIOCARTA_GSK3_PATHWAY 2726All SZGR genes in this pathway
BIOCARTA_RACCYCD_PATHWAY 2623All SZGR genes in this pathway
BIOCARTA_GLEEVEC_PATHWAY 2317All SZGR genes in this pathway
BIOCARTA_INSULIN_PATHWAY 2216All SZGR genes in this pathway
BIOCARTA_PPARA_PATHWAY 5843All SZGR genes in this pathway
BIOCARTA_MTOR_PATHWAY 2315All SZGR genes in this pathway
BIOCARTA_IGF1R_PATHWAY 2320All SZGR genes in this pathway
BIOCARTA_NGF_PATHWAY 1813All SZGR genes in this pathway
BIOCARTA_NFAT_PATHWAY 5645All SZGR genes in this pathway
BIOCARTA_PDGF_PATHWAY 3225All SZGR genes in this pathway
BIOCARTA_EDG1_PATHWAY 2724All SZGR genes in this pathway
BIOCARTA_PTEN_PATHWAY 1814All SZGR genes in this pathway
BIOCARTA_RAC1_PATHWAY 2316All SZGR genes in this pathway
BIOCARTA_RAS_PATHWAY 2320All SZGR genes in this pathway
BIOCARTA_NKCELLS_PATHWAY 2013All SZGR genes in this pathway
BIOCARTA_BAD_PATHWAY 2623All SZGR genes in this pathway
BIOCARTA_EIF4_PATHWAY 2419All SZGR genes in this pathway
BIOCARTA_HER2_PATHWAY 2217All SZGR genes in this pathway
BIOCARTA_ERK5_PATHWAY 1815All SZGR genes in this pathway
BIOCARTA_ACH_PATHWAY 1613All SZGR genes in this pathway
BIOCARTA_CDC42RAC_PATHWAY 1613All SZGR genes in this pathway
BIOCARTA_MET_PATHWAY 3730All SZGR genes in this pathway
BIOCARTA_IGF1MTOR_PATHWAY 2014All SZGR genes in this pathway
BIOCARTA_TCR_PATHWAY 4937All SZGR genes in this pathway
BIOCARTA_CTLA4_PATHWAY 2118All SZGR genes in this pathway
BIOCARTA_LONGEVITY_PATHWAY 1513All SZGR genes in this pathway
BIOCARTA_PAR1_PATHWAY 3728All SZGR genes in this pathway
BIOCARTA_TPO_PATHWAY 2417All SZGR genes in this pathway
BIOCARTA_CREB_PATHWAY 2725All SZGR genes in this pathway
BIOCARTA_TFF_PATHWAY 2115All SZGR genes in this pathway
BIOCARTA_TRKA_PATHWAY 1210All SZGR genes in this pathway
BIOCARTA_ARF_PATHWAY 1713All SZGR genes in this pathway
BIOCARTA_VEGF_PATHWAY 2918All SZGR genes in this pathway
ST_DIFFERENTIATION_PATHWAY_IN_PC12_CELLS 4535All SZGR genes in this pathway
SIG_CD40PATHWAYMAP 3428All SZGR genes in this pathway
SIG_PIP3_SIGNALING_IN_CARDIAC_MYOCTES 6754All SZGR genes in this pathway
SIG_CHEMOTAXIS 4537All SZGR genes in this pathway
SIG_IL4RECEPTOR_IN_B_LYPHOCYTES 2723All SZGR genes in this pathway
ST_ADRENERGIC 3629All SZGR genes in this pathway
ST_INTEGRIN_SIGNALING_PATHWAY 8262All SZGR genes in this pathway
SIG_INSULIN_RECEPTOR_PATHWAY_IN_CARDIAC_MYOCYTES 5141All SZGR genes in this pathway
SIG_PIP3_SIGNALING_IN_B_LYMPHOCYTES 3631All SZGR genes in this pathway
SIG_BCR_SIGNALING_PATHWAY 4638All SZGR genes in this pathway
ST_B_CELL_ANTIGEN_RECEPTOR 4032All SZGR genes in this pathway
ST_INTERLEUKIN_4_PATHWAY 2618All SZGR genes in this pathway
SA_PTEN_PATHWAY 1714All SZGR genes in this pathway
SA_TRKA_RECEPTOR 1715All SZGR genes in this pathway
ST_PHOSPHOINOSITIDE_3_KINASE_PATHWAY 3729All SZGR genes in this pathway
PID_FCER1_PATHWAY 6243All SZGR genes in this pathway
PID_BCR_5PATHWAY 6550All SZGR genes in this pathway
PID_ERBB4_PATHWAY 3832All SZGR genes in this pathway
PID_INSULIN_PATHWAY 4532All SZGR genes in this pathway
PID_GMCSF_PATHWAY 3731All SZGR genes in this pathway
PID_NFKAPPAB_ATYPICAL_PATHWAY 1715All SZGR genes in this pathway
PID_IL4_2PATHWAY 6543All SZGR genes in this pathway
PID_ER_NONGENOMIC_PATHWAY 4135All SZGR genes in this pathway
PID_MET_PATHWAY 8060All SZGR genes in this pathway
PID_PTP1B_PATHWAY 5240All SZGR genes in this pathway
PID_EPHB_FWD_PATHWAY 4038All SZGR genes in this pathway
PID_AVB3_OPN_PATHWAY 3129All SZGR genes in this pathway
PID_REELIN_PATHWAY 2929All SZGR genes in this pathway
PID_NECTIN_PATHWAY 3020All SZGR genes in this pathway
PID_TRAIL_PATHWAY 2820All SZGR genes in this pathway
PID_CDC42_PATHWAY 7051All SZGR genes in this pathway
PID_RET_PATHWAY 3929All SZGR genes in this pathway
PID_TCPTP_PATHWAY 4333All SZGR genes in this pathway
PID_ANGIOPOIETIN_RECEPTOR_PATHWAY 5041All SZGR genes in this pathway
PID_FAS_PATHWAY 3829All SZGR genes in this pathway
PID_SHP2_PATHWAY 5846All SZGR genes in this pathway
PID_NETRIN_PATHWAY 3227All SZGR genes in this pathway
PID_IL1_PATHWAY 3428All SZGR genes in this pathway
PID_IL2_1PATHWAY 5543All SZGR genes in this pathway
PID_CXCR4_PATHWAY 10278All SZGR genes in this pathway
PID_IGF1_PATHWAY 3023All SZGR genes in this pathway
PID_ERBB1_RECEPTOR_PROXIMAL_PATHWAY 3529All SZGR genes in this pathway
PID_IL5_PATHWAY 1411All SZGR genes in this pathway
PID_PI3KCI_PATHWAY 4940All SZGR genes in this pathway
PID_IL2_PI3K_PATHWAY 3427All SZGR genes in this pathway
PID_P75_NTR_PATHWAY 6951All SZGR genes in this pathway
PID_ECADHERIN_NASCENT_AJ_PATHWAY 3933All SZGR genes in this pathway
PID_AVB3_INTEGRIN_PATHWAY 7553All SZGR genes in this pathway
PID_IFNG_PATHWAY 4034All SZGR genes in this pathway
PID_ERBB1_DOWNSTREAM_PATHWAY 10578All SZGR genes in this pathway
PID_ERBB2_ERBB3_PATHWAY 4435All SZGR genes in this pathway
PID_IL3_PATHWAY 2719All SZGR genes in this pathway
PID_IL6_7_PATHWAY 4740All SZGR genes in this pathway
PID_ECADHERIN_KERATINOCYTE_PATHWAY 2119All SZGR genes in this pathway
PID_PDGFRB_PATHWAY 129103All SZGR genes in this pathway
PID_TRKR_PATHWAY 6248All SZGR genes in this pathway
PID_NEPHRIN_NEPH1_PATHWAY 3124All SZGR genes in this pathway
PID_IL23_PATHWAY 3730All SZGR genes in this pathway
PID_PDGFRA_PATHWAY 2218All SZGR genes in this pathway
PID_HEDGEHOG_2PATHWAY 2217All SZGR genes in this pathway
PID_AR_NONGENOMIC_PATHWAY 3127All SZGR genes in this pathway
PID_ERBB1_INTERNALIZATION_PATHWAY 4135All SZGR genes in this pathway
PID_CXCR3_PATHWAY 4334All SZGR genes in this pathway
PID_VEGFR1_PATHWAY 2623All SZGR genes in this pathway
PID_KIT_PATHWAY 5240All SZGR genes in this pathway
PID_IL2_STAT5_PATHWAY 3023All SZGR genes in this pathway
PID_VEGFR1_2_PATHWAY 6957All SZGR genes in this pathway
PID_THROMBIN_PAR1_PATHWAY 4332All SZGR genes in this pathway
PID_A6B1_A6B4_INTEGRIN_PATHWAY 4635All SZGR genes in this pathway
PID_EPHRINB_REV_PATHWAY 3025All SZGR genes in this pathway
PID_NCADHERIN_PATHWAY 3332All SZGR genes in this pathway
PID_PI3K_PLC_TRK_PATHWAY 3631All SZGR genes in this pathway
PID_EPHA2_FWD_PATHWAY 1916All SZGR genes in this pathway
PID_LYMPH_ANGIOGENESIS_PATHWAY 2516All SZGR genes in this pathway
PID_FGF_PATHWAY 5537All SZGR genes in this pathway
PID_FAK_PATHWAY 5945All SZGR genes in this pathway
REACTOME_SIGNALLING_BY_NGF 217167All SZGR genes in this pathway
REACTOME_SIGNALING_BY_SCF_KIT 7859All SZGR genes in this pathway
REACTOME_CELL_CELL_COMMUNICATION 12077All SZGR genes in this pathway
REACTOME_SIGNALING_BY_ERBB4 9067All SZGR genes in this pathway
REACTOME_SIGNALING_BY_ERBB2 10178All SZGR genes in this pathway
REACTOME_SIGNALING_BY_CONSTITUTIVELY_ACTIVE_EGFR 1813All SZGR genes in this pathway
REACTOME_SIGNALING_BY_EGFR_IN_CANCER 10980All SZGR genes in this pathway
REACTOME_PI3K_EVENTS_IN_ERBB4_SIGNALING 3828All SZGR genes in this pathway
REACTOME_PI3K_EVENTS_IN_ERBB2_SIGNALING 4434All SZGR genes in this pathway
REACTOME_INSULIN_RECEPTOR_SIGNALLING_CASCADE 8764All SZGR genes in this pathway
REACTOME_CELL_SURFACE_INTERACTIONS_AT_THE_VASCULAR_WALL 9165All SZGR genes in this pathway
REACTOME_NGF_SIGNALLING_VIA_TRKA_FROM_THE_PLASMA_MEMBRANE 137105All SZGR genes in this pathway
REACTOME_SIGNALING_BY_FGFR_IN_DISEASE 12788All SZGR genes in this pathway
REACTOME_PHOSPHOLIPID_METABOLISM 198112All SZGR genes in this pathway
REACTOME_GASTRIN_CREB_SIGNALLING_PATHWAY_VIA_PKC_AND_MAPK 205136All SZGR genes in this pathway
REACTOME_SIGNALING_BY_FGFR1_MUTANTS 3020All SZGR genes in this pathway
REACTOME_SYNTHESIS_OF_PIPS_AT_THE_PLASMA_MEMBRANE 3123All SZGR genes in this pathway
REACTOME_SIGNALING_BY_FGFR1_FUSION_MUTANTS 1912All SZGR genes in this pathway
REACTOME_PI_METABOLISM 4834All SZGR genes in this pathway
REACTOME_SIGNALING_BY_FGFR_MUTANTS 4429All SZGR genes in this pathway
REACTOME_PI3K_AKT_ACTIVATION 3829All SZGR genes in this pathway
REACTOME_TCR_SIGNALING 5446All SZGR genes in this pathway
REACTOME_DOWNSTREAM_TCR_SIGNALING 3732All SZGR genes in this pathway
REACTOME_GAB1_SIGNALOSOME 3829All SZGR genes in this pathway
REACTOME_TIE2_SIGNALING 1713All SZGR genes in this pathway
REACTOME_SIGNALING_BY_GPCR 920449All SZGR genes in this pathway
REACTOME_SIGNALING_BY_PDGF 12293All SZGR genes in this pathway
REACTOME_GPVI_MEDIATED_ACTIVATION_CASCADE 3125All SZGR genes in this pathway
REACTOME_DOWNSTREAM_SIGNAL_TRANSDUCTION 9576All SZGR genes in this pathway
REACTOME_G_ALPHA_Q_SIGNALLING_EVENTS 184116All SZGR genes in this pathway
REACTOME_G_ALPHA1213_SIGNALLING_EVENTS 7456All SZGR genes in this pathway
REACTOME_CD28_CO_STIMULATION 3226All SZGR genes in this pathway
REACTOME_GPCR_DOWNSTREAM_SIGNALING 805368All SZGR genes in this pathway
REACTOME_COSTIMULATION_BY_THE_CD28_FAMILY 6348All SZGR genes in this pathway
REACTOME_CD28_DEPENDENT_PI3K_AKT_SIGNALING 2218All SZGR genes in this pathway
REACTOME_PI_3K_CASCADE 5639All SZGR genes in this pathway
REACTOME_DOWNSTREAM_SIGNALING_OF_ACTIVATED_FGFR 10074All SZGR genes in this pathway
REACTOME_SIGNALING_BY_ILS 10786All SZGR genes in this pathway
REACTOME_METABOLISM_OF_LIPIDS_AND_LIPOPROTEINS 478302All SZGR genes in this pathway
REACTOME_REGULATION_OF_SIGNALING_BY_CBL 1816All SZGR genes in this pathway
REACTOME_NEPHRIN_INTERACTIONS 2015All SZGR genes in this pathway
REACTOME_IL_3_5_AND_GM_CSF_SIGNALING 4334All SZGR genes in this pathway
REACTOME_IL_RECEPTOR_SHC_SIGNALING 2721All SZGR genes in this pathway
REACTOME_IL_2_SIGNALING 4134All SZGR genes in this pathway
REACTOME_SIGNALING_BY_INSULIN_RECEPTOR 10872All SZGR genes in this pathway
REACTOME_HEMOSTASIS 466331All SZGR genes in this pathway
REACTOME_IMMUNE_SYSTEM 933616All SZGR genes in this pathway
REACTOME_ADAPTIVE_IMMUNE_SYSTEM 539350All SZGR genes in this pathway
REACTOME_CYTOKINE_SIGNALING_IN_IMMUNE_SYSTEM 270204All SZGR genes in this pathway
REACTOME_PLATELET_ACTIVATION_SIGNALING_AND_AGGREGATION 208138All SZGR genes in this pathway
REACTOME_SIGNALING_BY_FGFR 11280All SZGR genes in this pathway
REACTOME_PI3K_CASCADE 7151All SZGR genes in this pathway
ONKEN_UVEAL_MELANOMA_DN 526357All SZGR genes in this pathway
RODRIGUES_DCC_TARGETS_DN 12184All SZGR genes in this pathway
RODRIGUES_NTN1_TARGETS_DN 158102All SZGR genes in this pathway
DITTMER_PTHLH_TARGETS_DN 7351All SZGR genes in this pathway
RODRIGUES_THYROID_CARCINOMA_ANAPLASTIC_UP 722443All SZGR genes in this pathway
GAUSSMANN_MLL_AF4_FUSION_TARGETS_C_UP 170114All SZGR genes in this pathway
HAMAI_APOPTOSIS_VIA_TRAIL_UP 584356All SZGR genes in this pathway
MYLLYKANGAS_AMPLIFICATION_HOT_SPOT_7 86All SZGR genes in this pathway
NUYTTEN_EZH2_TARGETS_UP 1037673All SZGR genes in this pathway
BUYTAERT_PHOTODYNAMIC_THERAPY_STRESS_UP 811508All SZGR genes in this pathway
LOCKWOOD_AMPLIFIED_IN_LUNG_CANCER 214139All SZGR genes in this pathway
GOTTWEIN_TARGETS_OF_KSHV_MIR_K12_11 6345All SZGR genes in this pathway
TCGA_GLIOBLASTOMA_COPY_NUMBER_UP 7536All SZGR genes in this pathway
DING_LUNG_CANCER_EXPRESSION_BY_COPY_NUMBER 10062All SZGR genes in this pathway
CUI_TCF21_TARGETS_2_DN 830547All SZGR genes in this pathway
ZHANG_RESPONSE_TO_CANTHARIDIN_DN 6946All SZGR genes in this pathway
XU_GH1_AUTOCRINE_TARGETS_DN 14294All SZGR genes in this pathway
YIH_RESPONSE_TO_ARSENITE_C1 2414All SZGR genes in this pathway
KRIGE_RESPONSE_TO_TOSEDOSTAT_6HR_UP 953554All SZGR genes in this pathway
KRIGE_RESPONSE_TO_TOSEDOSTAT_24HR_UP 783442All SZGR genes in this pathway
WALLACE_PROSTATE_CANCER_RACE_DN 8842All SZGR genes in this pathway
GRESHOCK_CANCER_COPY_NUMBER_UP 323240All SZGR genes in this pathway
TCGA_GLIOBLASTOMA_MUTATED 88All SZGR genes in this pathway
SAKAI_CHRONIC_HEPATITIS_VS_LIVER_CANCER_UP 8363All SZGR genes in this pathway
KYNG_WERNER_SYNDROM_AND_NORMAL_AGING_UP 9362All SZGR genes in this pathway
DELPUECH_FOXO3_TARGETS_UP 6849All SZGR genes in this pathway
miRNA Targets ?
miRNA familyTarget positionmiRNA IDmiRNA seq
UTR startUTR endMatch method
miR-124.12412481A,m8hsa-miR-124aUUAAGGCACGCGGUGAAUGCCA
miR-124/5062412471Ahsa-miR-506UAAGGCACCCUUCUGAGUAGA
hsa-miR-124brainUAAGGCACGCGGUGAAUGCC
miR-1363343401Ahsa-miR-136ACUCCAUUUGUUUUGAUGAUGGA
miR-3202112171Ahsa-miR-320AAAAGCUGGGUUGAGAGGGCGAA
miR-378*2472541A,m8hsa-miR-422bCUGGACUUGGAGUCAGAAGGCC
hsa-miR-422aCUGGACUUAGGGUCAGAAGGCC
  • SZ: miRNAs which differentially expressed in brain cortex of schizophrenia patients comparing with control samples using microarray. Click here to see the list of SZ related miRNAs.
  • Brain: miRNAs which are expressed in brain based on miRNA microarray expression studies. Click here to see the list of brain related miRNAs.


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