Search results: The pahtway p175 has 84 genes in the original annotation. Currently, there are 67 genes in SZGR 2.0 (with evidence in schizophrenia) that are present at this pathway.

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Gene ID Symbol Synonyms Official Full Name Location SZ group ? Functional group ?
3688ITGB1CD29 | FNRB | GPIIA | MDF2 | MSK12 | VLA-BETA | VLABintegrin subunit beta 110p11.2CV:GWASdb
CV:PGCnp
GO_Annotation
Network
5728PTEN10q23del | BZS | CWS1 | DEC | GLM2 | MHAM | MMAC1 | PTEN1 | TEP1phosphatase and tensin homolog10q23.3CV:PGCnp
DMG:Wockner_2014
GO_Annotation
Network
PMID:cooccur
CompositeSet
Darnell FMRP targets
1147CHUKIKBKA | IKK-alpha | IKK1 | IKKA | NFKBIKA | TCF16conserved helix-loop-helix ubiquitous kinase10q24-q25CV:PGCnp
Network
7189TRAF6MGC:3310 | RNF85TNF receptor associated factor 611p12CV:PGCnp
GO_Annotation
Network
5970RELANFKB3 | p65v-rel avian reticuloendotheliosis viral oncogene homolog A11q13CV:PGCnp
DNM:Ambalavanan_2016
Network
PMID:cooccur
595CCND1BCL1 | D11S287E | PRAD1 | U21B31cyclin D111q13DMG:Jaffe_2016
Network
PMID:cooccur
330BIRC3AIP1 | API2 | CIAP2 | HAIP1 | HIAP1 | MALT2 | MIHC | RNF49 | c-IAP2baculoviral IAP repeat containing 311q22CV:PGCnp
DMG:vanEijk_2014
PMID:cooccur
1027CDKN1BCDKN4 | KIP1 | MEN1B | MEN4 | P27KIP1cyclin-dependent kinase inhibitor 1B12p13.1-p12CV:PGCnp
Network
PMID:cooccur
1019CDK4CMM3 | PSK-J3cyclin-dependent kinase 412q14CV:PGCnp
DMG:Jaffe_2016
GO_Annotation
Network
PMID:cooccur
5925RB1OSRC | PPP1R130 | RB | p105-Rb | pRb | pp110retinoblastoma 113q14.2CV:PGCnp
Network
PMID:cooccur
1282COL4A1BSVD | RATORcollagen type IV alpha 113q34CV:GWASdb
CV:PGCnp
1284COL4A2ICH | POREN2collagen type IV alpha 213q34CV:GWAScat
CV:GWASdb
CV:PGCnp
4792NFKBIAIKBA | MAD-3 | NFKBINFKB inhibitor alpha14q13CV:GWASdb
CV:PGCnp
Network
4149MAXbHLHd4MYC associated factor X14q23CV:PGCnp
PMID:cooccur
207AKT1AKT | CWS6 | PKB | PKB-ALPHA | PRKBA | RAC | RAC-ALPHAv-akt murine thymoma viral oncogene homolog 114q32.32Association
Core
CV:PGCnp
DMG:vanEijk_2014
DMG:Wockner_2014
DNM:Fromer_2014
GR_COR
GR_Ng
GR_WM
Network
PMID:cooccur
G2Cdb.humanPSD
G2Cdb.humanPSP
CompositeSet
7187TRAF3CAP-1 | CAP1 | CD40bp | CRAF1 | IIAE5 | LAP1TNF receptor associated factor 314q32.32CV:GWAScat
CV:GWASdb
CV:PGCnp
Expression
G2Cdb.human_BAYES-COLLINS-MOUSE-PSD-CONSENSUS
G2Cdb.humanPSD
G2Cdb.humanPSP
8554PIAS1DDXBP1 | GBP | GU/RH-II | ZMIZ3protein inhibitor of activated STAT 115qCV:GWASdb
CV:PGCnp
DMG:Nishioka_2013
23533PIK3R5F730038I15Rik | FOAP-2 | P101-PI3K | p101phosphoinositide-3-kinase regulatory subunit 517p13.1CV:GWASdb
CV:PGCnp
7157TP53BCC7 | LFS1 | P53 | TRP53tumor protein p5317p13.1Association
Core
CV:PGCnp
GO_Annotation
GR_COR
GR_Ng
GR_WM
Network
PMID:cooccur
9618TRAF4CART1 | MLN62 | RNF83TNF receptor associated factor 417q11-q12CV:PGCnp
PMID:cooccur
4843NOS2HEP-NOS | INOS | NOS | NOS2Anitric oxide synthase 217q11.2CV:GWASdb
CV:PGCnp
DNM:Fromer_2014
PMID:cooccur
CompositeSet
3675ITGA3CD49C | FRP-2 | GAP-B3 | GAPB3 | ILNEB | MSK18 | VCA-2 | VL3A | VLA3aintegrin subunit alpha 317q21.33CV:PGCnp
DNM:Gulsuner_2013
GO_Annotation
PMID:cooccur
284217LAMA1LAMA | PTBHS | S-LAM-alphalaminin subunit alpha 118p11.3CV:PGCnp
DNM:Girard_2011
GO_Annotation
CompositeSet
9063PIAS2ARIP3 | DIP | MIZ | MIZ1 | PIASX | PIASX-ALPHA | PIASX-BETA | SIZ2 | ZMIZ4protein inhibitor of activated STAT 218q21.1CV:PGCnp
PMID:cooccur
596BCL2Bcl-2 | PPP1R50B-cell CLL/lymphoma 218q21.3CV:PGCnp
DMG:Wockner_2014
GO_Annotation
Network
PMID:cooccur
898CCNE1CCNE | pCCNE1cyclin E119q12CV:PGCnp
DMG:Montano_2016
Network
208AKT2HIHGHH | PKBB | PKBBETA | PRKBB | RAC-BETAv-akt murine thymoma viral oncogene homolog 219q13.1-q13.2CV:PGCnp
Network
PMID:cooccur
G2Cdb.humanNRC
G2Cdb.humanPSD
G2Cdb.humanPSP
5296PIK3R2MPPH | MPPH1 | P85B | p85 | p85-BETAphosphoinositide-3-kinase regulatory subunit 219q13.2-q13.4CV:PGCnp
DMG:Wockner_2014
Network
8503PIK3R3p55 | p55-GAMMA | p55PIKphosphoinositide-3-kinase regulatory subunit 31p34.1CV:PGCnp
DNM:Fromer_2014
Network
CompositeSet
1870E2F2E2F-2E2F transcription factor 21p36CV:GWASdb
DMG:Wockner_2014
5293PIK3CDAPDS | IMD14 | P110DELTA | PI3K | p110Dphosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta1p36.2CV:PGCnp
DMG:Wockner_2014
PMID:cooccur
842CASP9APAF-3 | APAF3 | ICE-LAP6 | MCH6 | PPP1R56caspase 91p36.21DMG:Wockner_2014
10401PIAS3ZMIZ5protein inhibitor of activated STAT 31q21CNV:YES
GSMA_I
GSMA_IIA
PMID:cooccur
1163CKS1BCKS1 | PNAS-16 | PNAS-18 | ckshs1CDC28 protein kinase regulatory subunit 1B1q21.2CV:PGCnp
DMG:Nishioka_2013
GSMA_I
GSMA_IIA
6258RXRGNR2B3 | RXRCretinoid X receptor gamma1q22-q23CV:PGCnp
CV:PheWAS
DMG:Jaffe_2016
5743PTGS2COX-2 | COX2 | GRIPGHS | PGG/HS | PGHS-2 | PHS-2 | hCox-2prostaglandin-endoperoxide synthase 21q25.2-q25.3Association
CV:GWAScat
CV:GWASdb
CV:PGCnp
PMID:cooccur
7188TRAF5MGC:39780 | RNF84TNF receptor associated factor 51q32CV:PGCnp
DMG:Wockner_2014
10000AKT3MPPH | MPPH2 | PKB-GAMMA | PKBG | PRKBG | RAC-PK-gamma | RAC-gamma | STK-2v-akt murine thymoma viral oncogene homolog 31q44CV:GWAScat
CV:GWASdb
CV:PGC128
CV:PGCnp
CV:Ripke_2013
LK:YES
PMID:cooccur
CompositeSet
Darnell FMRP targets
598BCL2L1BCL-XL/S | BCL2L | BCLX | Bcl-X | PPP1R52BCL2 like 120q11.21GO_Annotation
Network
PMID:cooccur
3911LAMA5-laminin subunit alpha 520q13.2-q13.3CV:PGCnp
DMG:Wockner_2014
PMID:cooccur
3685ITGAVCD51 | MSK8 | VNRA | VTNRintegrin subunit alpha V2q31-q32CV:PGCnp
DMG:Wockner_2014
3655ITGA6CD49f | ITGA6B | VLA-6integrin subunit alpha 62q31.1CV:PGCnp
DMG:Nishioka_2013
DNM:Ambalavanan_2016
DNM:Xu_2012
Expression
PMID:cooccur
CompositeSet
2335FN1CIG | ED-B | FINC | FN | FNZ | GFND | GFND2 | LETS | MSFfibronectin 12q34CV:PGCnp
DNM:Fromer_2014
DNM:Guipponi_2014
GR_Ng
GSMA_IIA
GSMA_IIE
PMID:cooccur
CompositeSet
1286COL4A4CA44collagen type IV alpha 42q35-q37CV:PGCnp
GO_Annotation
GSMA_IIA
GSMA_IIE
PMID:cooccur
2272FHITAP3Aase | FRA3Bfragile histidine triad3p14.2CV:GWASdb
CV:PGCnp
DMG:Nishioka_2013
PMID:cooccur
Potential synaptic genes
3913LAMB2LAMS | NPHS5laminin subunit beta 23p21CV:PGCnp
GO_Annotation
5915RARBHAP | MCOPS12 | NR1B2 | RRB2retinoic acid receptor beta3p24.2CV:GWASdb
CV:PGCnp
GSMA_I
5291PIK3CBP110BETA | PI3K | PI3KBETA | PIK3C1phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta3q22.3CV:PGCnp
DNM:Girard_2011
Network
CompositeSet
5290PIK3CACLOVE | CWS5 | MCAP | MCM | MCMTC | PI3K | p110-alphaphosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha3q26.3CV:PGCnp
Network
PMID:cooccur
G2Cdb.humanNRC
G2Cdb.humanPSD
G2Cdb.humanPSP
Potential synaptic genes
4790NFKB1CVID12 | EBP-1 | KBF1 | NF-kB1 | NF-kappa-B | NF-kappaB | NFKB-p105 | NFKB-p50 | NFkappaB | p105 | p50nuclear factor of kappa light polypeptide gene enhancer in B-cells 14q24CV:GWAScat
CV:GWASdb
CV:PGCnp
Network
PMID:cooccur
Ascano FMRP targets
6502SKP2FBL1 | FBXL1 | FLB1 | p45S-phase kinase-associated protein 2, E3 ubiquitin protein ligase5p13CV:PGCnp
3673ITGA2BR | CD49B | GPIa | HPA-5 | VLA-2 | VLAA2integrin subunit alpha 25q11.2CV:PGCnp
DMG:Jaffe_2016
DMG:Montano_2016
Ascano FMRP targets
5295PIK3R1AGM7 | GRB1 | IMD36 | p85 | p85-ALPHAphosphoinositide-3-kinase regulatory subunit 15q13.1CV:PGCnp
DMG:Montano_2016
DMG:Wockner_2014
Network
PMID:cooccur
6257RXRBDAUDI6 | H-2RIIBP | NR2B2 | RCoR-1retinoid X receptor beta6p21.3CV:PGCnp
DMG:Wockner_2014
GSMA_I
PMID:cooccur
1871E2F3E2F-3E2F transcription factor 36p22CV:PGCnp
DMG:Jaffe_2016
GSMA_I
3910LAMA4CMD1JJ | LAMA3 | LAMA4*-1laminin subunit alpha 46q21CV:PGCnp
DNM:Fromer_2014
GO_Annotation
CompositeSet
3908LAMA2LAMMlaminin subunit alpha 26q22-q23CV:PGCnp
DMG:Wockner_2014
DNM:Gulsuner_2013
DNM:Xu_2012
GO_Annotation
PMID:cooccur
CompositeSet
1021CDK6MCPH12 | PLSTIREcyclin-dependent kinase 67q21-q22CV:PGCnp
DMG:Jaffe_2016
GO_Annotation
Network
PMID:cooccur
3551IKBKBIKK-beta | IKK2 | IKKB | IMD15 | NFKBIKBinhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta8p11.2CV:PGCnp
DMG:Wockner_2014
Network
9134CCNE2CYCE2cyclin E28q22.1DMG:Jaffe_2016
4609MYCMRTL | MYCC | bHLHe39 | c-Mycv-myc avian myelocytomatosis viral oncogene homolog8q24.21CV:PGCnp
DMG:Jaffe_2016
Expression
Network
PMID:cooccur
5747PTK2FADK | FAK | FAK1 | FRNK | PPP1R71 | p125FAK | pp125FAKprotein tyrosine kinase 28q24.3CV:PGCnp
DMG:Wockner_2014
GO_Annotation
Network
PMID:cooccur
G2Cdb.human_BAYES-COLLINS-HUMAN-PSD-FULL
CompositeSet
Darnell FMRP targets
7185TRAF1EBI6 | MGC:10353TNF receptor associated factor 19q33-q34CV:PGCnp
PMID:cooccur
7186TRAF2MGC:45012 | TRAP | TRAP3TNF receptor associated factor 29q34CV:PGCnp
Network
PMID:cooccur
Ascano FMRP targets
10319LAMC3OCCMlaminin subunit gamma 39q34.12CV:GWASdb
CV:PGCnp
DMG:Wockner_2014
6256RXRANR2B1retinoid X receptor alpha9q34.3CV:GWAScat
CV:PGCnp
PMID:cooccur
331XIAPAPI3 | BIRC4 | IAP-3 | ILP1 | MIHA | XLP2 | hIAP-3 | hIAP3X-linked inhibitor of apoptosisXq25CV:PGCnp
Network
PMID:cooccur