Gene Page: CCNE1
Summary ?
GeneID | 898 |
Symbol | CCNE1 |
Synonyms | CCNE|pCCNE1 |
Description | cyclin E1 |
Reference | MIM:123837|HGNC:HGNC:1589|Ensembl:ENSG00000105173|HPRD:00455|Vega:OTTHUMG00000177626 |
Gene type | protein-coding |
Map location | 19q12 |
Pascal p-value | 0.276 |
Fetal beta | -1.146 |
DMG | 1 (# studies) |
eGene | Myers' cis & trans Meta |
Gene in Data Sources
Gene set name | Method of gene set | Description | Info |
---|---|---|---|
CV:PGCnp | Genome-wide Association Study | GWAS | |
DMG:Montano_2016 | Genome-wide DNA methylation analysis | This dataset includes 172 replicated associations between CpGs with schizophrenia. | 1 |
Network | Shortest path distance of core genes in the Human protein-protein interaction network | Contribution to shortest path in PPI network: 0.004 |
Section I. Genetics and epigenetics annotation
Differentially methylated gene
Probe | Chromosome | Position | Nearest gene | P (dis) | Beta (dis) | FDR (dis) | Study |
---|---|---|---|---|---|---|---|
cg06636316 | 19 | 30303495 | CCNE1 | 1.07E-4 | -0.006 | 0.123 | DMG:Montano_2016 |
eQTL annotation
SNP ID | Chromosome | Position | eGene | Gene Entrez ID | pvalue | qvalue | TSS distance | eQTL type |
---|---|---|---|---|---|---|---|---|
rs1578978 | chr8 | 118196802 | CCNE1 | 898 | 0.18 | trans |
Section II. Transcriptome annotation
General gene expression (GTEx)
Gene expression during devlopment (BrainCloud)
Footnote:
A total of 269 time points ploted, with n=38 fetal samples (x=1:38). Each triangle represents one time point.
Gene expression of temporal and spatial changes (BrainSpan)
Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes the lower 25% and upper 25% of the expression distribution.
No co-expressed genes in brain regions
Section III. Gene Ontology annotation
Molecular function | GO term | Evidence | Neuro keywords | PubMed ID |
---|---|---|---|---|
GO:0003713 | transcription coactivator activity | NAS | 15572661 | |
GO:0005515 | protein binding | IPI | 9891079 | |
GO:0050681 | androgen receptor binding | NAS | 15572661 | |
Biological process | GO term | Evidence | Neuro keywords | PubMed ID |
GO:0000082 | G1/S transition of mitotic cell cycle | NAS | 8207080 | |
GO:0007049 | cell cycle | IEA | - | |
GO:0051301 | cell division | IEA | - | |
GO:0030521 | androgen receptor signaling pathway | NAS | 15572661 | |
GO:0045893 | positive regulation of transcription, DNA-dependent | NAS | 15572661 | |
Cellular component | GO term | Evidence | Neuro keywords | PubMed ID |
GO:0005829 | cytosol | EXP | 7799941 |11907280 | |
GO:0005634 | nucleus | NAS | - | |
GO:0005654 | nucleoplasm | EXP | 7629134 |10454565 |
Section IV. Protein-protein interaction annotation
Interactors | Aliases B | Official full name B | Experimental | Source | PubMed ID |
---|---|---|---|---|---|
AR | AIS | DHTR | HUMARA | KD | NR3C4 | SBMA | SMAX1 | TFM | androgen receptor | - | HPRD,BioGRID | 10953010 |
BRCA1 | BRCAI | BRCC1 | IRIS | PSCP | RNF53 | breast cancer 1, early onset | Affinity Capture-Western | BioGRID | 17525332 |
CABLES1 | CABLES | FLJ35924 | HsT2563 | IK3-1 | Cdk5 and Abl enzyme substrate 1 | - | HPRD | 11733001 |
CCT4 | CCT-DELTA | Cctd | MGC126164 | MGC126165 | SRB | chaperonin containing TCP1, subunit 4 (delta) | - | HPRD,BioGRID | 9819444 |
CDC2 | CDC28A | CDK1 | DKFZp686L20222 | MGC111195 | cell division cycle 2, G1 to S and G2 to M | - | HPRD,BioGRID | 1388288 |
CDC25A | CDC25A2 | cell division cycle 25 homolog A (S. pombe) | - | HPRD,BioGRID | 8617791 |
CDK2 | p33(CDK2) | cyclin-dependent kinase 2 | - | HPRD,BioGRID | 1388288 |
CDK3 | - | cyclin-dependent kinase 3 | - | HPRD,BioGRID | 11733001 |
CDKN1A | CAP20 | CDKN1 | CIP1 | MDA-6 | P21 | SDI1 | WAF1 | p21CIP1 | cyclin-dependent kinase inhibitor 1A (p21, Cip1) | p21 interacts with cyclin E. | BIND | 9632134 |
CDKN1A | CAP20 | CDKN1 | CIP1 | MDA-6 | P21 | SDI1 | WAF1 | p21CIP1 | cyclin-dependent kinase inhibitor 1A (p21, Cip1) | Affinity Capture-Western | BioGRID | 12839982 |
CDKN1A | CAP20 | CDKN1 | CIP1 | MDA-6 | P21 | SDI1 | WAF1 | p21CIP1 | cyclin-dependent kinase inhibitor 1A (p21, Cip1) | CDKN1A (p21) interacts with CCNE1 (cyclin E). | BIND | 8662825 |
CDKN1B | CDKN4 | KIP1 | MEN1B | MEN4 | P27KIP1 | cyclin-dependent kinase inhibitor 1B (p27, Kip1) | p27 interacts with cyclin E. | BIND | 9632134 |
CDKN1B | CDKN4 | KIP1 | MEN1B | MEN4 | P27KIP1 | cyclin-dependent kinase inhibitor 1B (p27, Kip1) | p27 interacts with Cyc E. | BIND | 15469821 |
CDKN1B | CDKN4 | KIP1 | MEN1B | MEN4 | P27KIP1 | cyclin-dependent kinase inhibitor 1B (p27, Kip1) | Affinity Capture-Western | BioGRID | 9891079 |12529437 |
COIL | CLN80 | p80-coilin | coilin | - | HPRD,BioGRID | 10751146 |
CUL3 | - | cullin 3 | - | HPRD,BioGRID | 10500095 |
E2F4 | E2F-4 | E2F transcription factor 4, p107/p130-binding | Affinity Capture-Western | BioGRID | 9891079 |
FBXW7 | AGO | CDC4 | DKFZp686F23254 | FBW6 | FBW7 | FBX30 | FBXO30 | FBXW6 | FLJ16457 | SEL-10 | SEL10 | F-box and WD repeat domain containing 7 | Phosphorylated cycE interacts with Fbw7. This interaction was modeled on a demonstrated interaction between cycE from human and Fbw7 from an unspecified species. | BIND | 14739463 |
FBXW7 | AGO | CDC4 | DKFZp686F23254 | FBW6 | FBW7 | FBX30 | FBXO30 | FBXW6 | FLJ16457 | SEL-10 | SEL10 | F-box and WD repeat domain containing 7 | - | HPRD,BioGRID | 11533444 |11565033 |14536078 |
FBXW7 | AGO | CDC4 | DKFZp686F23254 | FBW6 | FBW7 | FBX30 | FBXO30 | FBXW6 | FLJ16457 | SEL-10 | SEL10 | F-box and WD repeat domain containing 7 | hCDC4 interacts with cyclin E. This interaction was modelled on a demonstrated interaction between human CDC4 and cyclin E from an unspecified species. | BIND | 14999283 |
GSK3B | - | glycogen synthase kinase 3 beta | Biochemical Activity | BioGRID | 14536078 |
HERC5 | CEB1 | CEBP1 | hect domain and RLD 5 | - | HPRD,BioGRID | 10581175 |
PARK2 | AR-JP | LPRS2 | PDJ | PRKN | Parkinson disease (autosomal recessive, juvenile) 2, parkin | Affinity Capture-Western | BioGRID | 12628165 |
RBL1 | CP107 | MGC40006 | PRB1 | p107 | retinoblastoma-like 1 (p107) | - | HPRD | 8230483 |
RBL1 | CP107 | MGC40006 | PRB1 | p107 | retinoblastoma-like 1 (p107) | Affinity Capture-Western | BioGRID | 9891079 |
RBL2 | FLJ26459 | P130 | Rb2 | retinoblastoma-like 2 (p130) | - | HPRD,BioGRID | 8253383 |
REL | C-Rel | v-rel reticuloendotheliosis viral oncogene homolog (avian) | - | HPRD | 9731206 |
RRN3 | DKFZp566E104 | MGC104238 | TIFIA | RRN3 RNA polymerase I transcription factor homolog (S. cerevisiae) | Reconstituted Complex | BioGRID | 15004009 |
SF3B1 | PRP10 | PRPF10 | SAP155 | SF3b155 | splicing factor 3b, subunit 1, 155kDa | Affinity Capture-Western | BioGRID | 9891079 |
SKP2 | FBL1 | FBXL1 | FLB1 | MGC1366 | S-phase kinase-associated protein 2 (p45) | - | HPRD,BioGRID | 11237742 |
SMARCA2 | BAF190 | BRM | FLJ36757 | MGC74511 | SNF2 | SNF2L2 | SNF2LA | SWI2 | Sth1p | hBRM | hSNF2a | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2 | Affinity Capture-Western | BioGRID | 9891079 |
SMARCA4 | BAF190 | BRG1 | FLJ39786 | SNF2 | SNF2-BETA | SNF2L4 | SNF2LB | SWI2 | hSNF2b | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 | - | HPRD,BioGRID | 9891079 |
SMARCB1 | BAF47 | INI1 | RDT | SNF5 | SNF5L1 | Sfh1p | Snr1 | hSNFS | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1 | Affinity Capture-Western | BioGRID | 9891079 |
SMARCC1 | BAF155 | CRACC1 | Rsc8 | SRG3 | SWI3 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1 | - | HPRD,BioGRID | 9891079 |
Section V. Pathway annotation
Pathway name | Pathway size | # SZGR 2.0 genes in pathway | Info |
---|---|---|---|
KEGG CELL CYCLE | 128 | 84 | All SZGR 2.0 genes in this pathway |
KEGG OOCYTE MEIOSIS | 114 | 79 | All SZGR 2.0 genes in this pathway |
KEGG P53 SIGNALING PATHWAY | 69 | 45 | All SZGR 2.0 genes in this pathway |
KEGG PATHWAYS IN CANCER | 328 | 259 | All SZGR 2.0 genes in this pathway |
KEGG PROSTATE CANCER | 89 | 75 | All SZGR 2.0 genes in this pathway |
KEGG SMALL CELL LUNG CANCER | 84 | 67 | All SZGR 2.0 genes in this pathway |
BIOCARTA MCM PATHWAY | 18 | 8 | All SZGR 2.0 genes in this pathway |
BIOCARTA G1 PATHWAY | 28 | 21 | All SZGR 2.0 genes in this pathway |
BIOCARTA CELLCYCLE PATHWAY | 23 | 15 | All SZGR 2.0 genes in this pathway |
BIOCARTA SKP2E2F PATHWAY | 10 | 6 | All SZGR 2.0 genes in this pathway |
BIOCARTA RACCYCD PATHWAY | 26 | 23 | All SZGR 2.0 genes in this pathway |
BIOCARTA P53 PATHWAY | 16 | 13 | All SZGR 2.0 genes in this pathway |
BIOCARTA P27 PATHWAY | 13 | 10 | All SZGR 2.0 genes in this pathway |
SA REG CASCADE OF CYCLIN EXPR | 13 | 7 | All SZGR 2.0 genes in this pathway |
PID PRL SIGNALING EVENTS PATHWAY | 23 | 17 | All SZGR 2.0 genes in this pathway |
PID E2F PATHWAY | 74 | 48 | All SZGR 2.0 genes in this pathway |
PID MTOR 4PATHWAY | 69 | 55 | All SZGR 2.0 genes in this pathway |
PID FOXM1 PATHWAY | 40 | 30 | All SZGR 2.0 genes in this pathway |
PID BARD1 PATHWAY | 29 | 19 | All SZGR 2.0 genes in this pathway |
PID RB 1PATHWAY | 65 | 46 | All SZGR 2.0 genes in this pathway |
REACTOME G0 AND EARLY G1 | 25 | 13 | All SZGR 2.0 genes in this pathway |
REACTOME CELL CYCLE | 421 | 253 | All SZGR 2.0 genes in this pathway |
REACTOME CELL CYCLE MITOTIC | 325 | 185 | All SZGR 2.0 genes in this pathway |
REACTOME CELL CYCLE CHECKPOINTS | 124 | 70 | All SZGR 2.0 genes in this pathway |
REACTOME CYCLIN E ASSOCIATED EVENTS DURING G1 S TRANSITION | 65 | 40 | All SZGR 2.0 genes in this pathway |
REACTOME P53 DEPENDENT G1 DNA DAMAGE RESPONSE | 57 | 35 | All SZGR 2.0 genes in this pathway |
REACTOME G1 S TRANSITION | 112 | 63 | All SZGR 2.0 genes in this pathway |
REACTOME MITOTIC G1 G1 S PHASES | 137 | 79 | All SZGR 2.0 genes in this pathway |
REACTOME E2F MEDIATED REGULATION OF DNA REPLICATION | 35 | 17 | All SZGR 2.0 genes in this pathway |
REACTOME G1 S SPECIFIC TRANSCRIPTION | 19 | 9 | All SZGR 2.0 genes in this pathway |
REACTOME S PHASE | 109 | 66 | All SZGR 2.0 genes in this pathway |
REACTOME SCFSKP2 MEDIATED DEGRADATION OF P27 P21 | 56 | 34 | All SZGR 2.0 genes in this pathway |
VECCHI GASTRIC CANCER EARLY UP | 430 | 232 | All SZGR 2.0 genes in this pathway |
SENESE HDAC1 AND HDAC2 TARGETS UP | 238 | 144 | All SZGR 2.0 genes in this pathway |
GRAHAM CML DIVIDING VS NORMAL QUIESCENT UP | 181 | 101 | All SZGR 2.0 genes in this pathway |
GRAHAM NORMAL QUIESCENT VS NORMAL DIVIDING DN | 87 | 49 | All SZGR 2.0 genes in this pathway |
RODRIGUES THYROID CARCINOMA POORLY DIFFERENTIATED UP | 633 | 376 | All SZGR 2.0 genes in this pathway |
KOKKINAKIS METHIONINE DEPRIVATION 48HR UP | 128 | 95 | All SZGR 2.0 genes in this pathway |
KOKKINAKIS METHIONINE DEPRIVATION 96HR UP | 117 | 84 | All SZGR 2.0 genes in this pathway |
LINDGREN BLADDER CANCER CLUSTER 1 DN | 378 | 231 | All SZGR 2.0 genes in this pathway |
LINDGREN BLADDER CANCER CLUSTER 3 UP | 329 | 196 | All SZGR 2.0 genes in this pathway |
OUELLET OVARIAN CANCER INVASIVE VS LMP UP | 117 | 85 | All SZGR 2.0 genes in this pathway |
OUELLET CULTURED OVARIAN CANCER INVASIVE VS LMP UP | 69 | 40 | All SZGR 2.0 genes in this pathway |
NUNODA RESPONSE TO DASATINIB IMATINIB UP | 29 | 20 | All SZGR 2.0 genes in this pathway |
MARKS HDAC TARGETS UP | 23 | 15 | All SZGR 2.0 genes in this pathway |
KONG E2F3 TARGETS | 97 | 58 | All SZGR 2.0 genes in this pathway |
BAKER HEMATOPOESIS STAT5 TARGETS | 7 | 7 | All SZGR 2.0 genes in this pathway |
LI LUNG CANCER | 41 | 30 | All SZGR 2.0 genes in this pathway |
FARMER BREAST CANCER BASAL VS LULMINAL | 330 | 215 | All SZGR 2.0 genes in this pathway |
HONRADO BREAST CANCER BRCA1 VS BRCA2 | 18 | 12 | All SZGR 2.0 genes in this pathway |
DACOSTA UV RESPONSE VIA ERCC3 UP | 309 | 199 | All SZGR 2.0 genes in this pathway |
OXFORD RALA OR RALB TARGETS UP | 48 | 23 | All SZGR 2.0 genes in this pathway |
JAZAG TGFB1 SIGNALING UP | 108 | 69 | All SZGR 2.0 genes in this pathway |
JAZAG TGFB1 SIGNALING VIA SMAD4 DN | 66 | 38 | All SZGR 2.0 genes in this pathway |
PUJANA BREAST CANCER LIT INT NETWORK | 101 | 73 | All SZGR 2.0 genes in this pathway |
PUJANA BRCA1 PCC NETWORK | 1652 | 1023 | All SZGR 2.0 genes in this pathway |
PUJANA ATM PCC NETWORK | 1442 | 892 | All SZGR 2.0 genes in this pathway |
NUYTTEN EZH2 TARGETS DN | 1024 | 594 | All SZGR 2.0 genes in this pathway |
INGRAM SHH TARGETS DN | 64 | 41 | All SZGR 2.0 genes in this pathway |
BUYTAERT PHOTODYNAMIC THERAPY STRESS DN | 637 | 377 | All SZGR 2.0 genes in this pathway |
WEI MYCN TARGETS WITH E BOX | 795 | 478 | All SZGR 2.0 genes in this pathway |
LIAO METASTASIS | 539 | 324 | All SZGR 2.0 genes in this pathway |
FUJIWARA PARK2 IN LIVER CANCER UP | 8 | 7 | All SZGR 2.0 genes in this pathway |
GARCIA TARGETS OF FLI1 AND DAX1 DN | 176 | 104 | All SZGR 2.0 genes in this pathway |
BENPORATH CYCLING GENES | 648 | 385 | All SZGR 2.0 genes in this pathway |
GEORGES TARGETS OF MIR192 AND MIR215 | 893 | 528 | All SZGR 2.0 genes in this pathway |
STANELLE E2F1 TARGETS | 29 | 20 | All SZGR 2.0 genes in this pathway |
KANNAN TP53 TARGETS DN | 21 | 15 | All SZGR 2.0 genes in this pathway |
PEART HDAC PROLIFERATION CLUSTER UP | 57 | 35 | All SZGR 2.0 genes in this pathway |
MANALO HYPOXIA DN | 289 | 166 | All SZGR 2.0 genes in this pathway |
TENEDINI MEGAKARYOCYTE MARKERS | 66 | 48 | All SZGR 2.0 genes in this pathway |
TARTE PLASMA CELL VS PLASMABLAST DN | 309 | 206 | All SZGR 2.0 genes in this pathway |
ZHAN MULTIPLE MYELOMA CD1 AND CD2 DN | 51 | 32 | All SZGR 2.0 genes in this pathway |
NUMATA CSF3 SIGNALING VIA STAT3 | 22 | 17 | All SZGR 2.0 genes in this pathway |
VERNELL RETINOBLASTOMA PATHWAY UP | 70 | 47 | All SZGR 2.0 genes in this pathway |
ZAMORA NOS2 TARGETS UP | 69 | 41 | All SZGR 2.0 genes in this pathway |
GENTILE UV LOW DOSE UP | 27 | 19 | All SZGR 2.0 genes in this pathway |
WANG SMARCE1 TARGETS DN | 371 | 218 | All SZGR 2.0 genes in this pathway |
BROWNE HCMV INFECTION 8HR UP | 105 | 73 | All SZGR 2.0 genes in this pathway |
BROWNE HCMV INFECTION 48HR UP | 180 | 125 | All SZGR 2.0 genes in this pathway |
BROWNE HCMV INFECTION 14HR UP | 156 | 101 | All SZGR 2.0 genes in this pathway |
YAMAZAKI TCEB3 TARGETS DN | 215 | 132 | All SZGR 2.0 genes in this pathway |
SONG TARGETS OF IE86 CMV PROTEIN | 60 | 42 | All SZGR 2.0 genes in this pathway |
DEBIASI APOPTOSIS BY REOVIRUS INFECTION DN | 287 | 208 | All SZGR 2.0 genes in this pathway |
DAZARD RESPONSE TO UV NHEK DN | 318 | 220 | All SZGR 2.0 genes in this pathway |
WELCSH BRCA1 TARGETS DN | 141 | 92 | All SZGR 2.0 genes in this pathway |
BILD E2F3 ONCOGENIC SIGNATURE | 246 | 153 | All SZGR 2.0 genes in this pathway |
CREIGHTON ENDOCRINE THERAPY RESISTANCE 5 | 482 | 296 | All SZGR 2.0 genes in this pathway |
WANG LSD1 TARGETS UP | 24 | 14 | All SZGR 2.0 genes in this pathway |
MASSARWEH TAMOXIFEN RESISTANCE UP | 578 | 341 | All SZGR 2.0 genes in this pathway |
MARZEC IL2 SIGNALING UP | 115 | 80 | All SZGR 2.0 genes in this pathway |
OUYANG PROSTATE CANCER MARKERS | 19 | 16 | All SZGR 2.0 genes in this pathway |
MITSIADES RESPONSE TO APLIDIN DN | 249 | 165 | All SZGR 2.0 genes in this pathway |
SMID BREAST CANCER LUMINAL A DN | 18 | 7 | All SZGR 2.0 genes in this pathway |
SMID BREAST CANCER BASAL UP | 648 | 398 | All SZGR 2.0 genes in this pathway |
BONCI TARGETS OF MIR15A AND MIR16 1 | 91 | 75 | All SZGR 2.0 genes in this pathway |
WEST ADRENOCORTICAL TUMOR UP | 294 | 199 | All SZGR 2.0 genes in this pathway |
PODAR RESPONSE TO ADAPHOSTIN DN | 18 | 16 | All SZGR 2.0 genes in this pathway |
LU TUMOR ANGIOGENESIS UP | 25 | 22 | All SZGR 2.0 genes in this pathway |
MUELLER PLURINET | 299 | 189 | All SZGR 2.0 genes in this pathway |
RUIZ TNC TARGETS DN | 142 | 79 | All SZGR 2.0 genes in this pathway |
HOFFMANN LARGE TO SMALL PRE BII LYMPHOCYTE UP | 163 | 102 | All SZGR 2.0 genes in this pathway |
SHEDDEN LUNG CANCER POOR SURVIVAL A6 | 456 | 285 | All SZGR 2.0 genes in this pathway |
ZHANG TLX TARGETS 60HR DN | 277 | 166 | All SZGR 2.0 genes in this pathway |
HAN SATB1 TARGETS UP | 395 | 249 | All SZGR 2.0 genes in this pathway |
ISHIDA E2F TARGETS | 53 | 27 | All SZGR 2.0 genes in this pathway |
CHIANG LIVER CANCER SUBCLASS PROLIFERATION UP | 178 | 108 | All SZGR 2.0 genes in this pathway |
FONTAINE FOLLICULAR THYROID ADENOMA UP | 75 | 43 | All SZGR 2.0 genes in this pathway |
FONTAINE PAPILLARY THYROID CARCINOMA UP | 66 | 38 | All SZGR 2.0 genes in this pathway |
CAIRO HEPATOBLASTOMA CLASSES UP | 605 | 377 | All SZGR 2.0 genes in this pathway |
WHITFIELD CELL CYCLE LITERATURE | 44 | 25 | All SZGR 2.0 genes in this pathway |
BROWNE HCMV INFECTION 1HR DN | 222 | 147 | All SZGR 2.0 genes in this pathway |
WHITFIELD CELL CYCLE G1 S | 147 | 76 | All SZGR 2.0 genes in this pathway |
CHICAS RB1 TARGETS SENESCENT | 572 | 352 | All SZGR 2.0 genes in this pathway |
WANG RESPONSE TO GSK3 INHIBITOR SB216763 DN | 374 | 217 | All SZGR 2.0 genes in this pathway |
LU EZH2 TARGETS DN | 414 | 237 | All SZGR 2.0 genes in this pathway |
ACOSTA PROLIFERATION INDEPENDENT MYC TARGETS UP | 84 | 51 | All SZGR 2.0 genes in this pathway |
BRUINS UVC RESPONSE LATE | 1137 | 655 | All SZGR 2.0 genes in this pathway |
LINSLEY MIR16 TARGETS | 206 | 127 | All SZGR 2.0 genes in this pathway |
LEE BMP2 TARGETS DN | 882 | 538 | All SZGR 2.0 genes in this pathway |
GOBERT OLIGODENDROCYTE DIFFERENTIATION UP | 570 | 339 | All SZGR 2.0 genes in this pathway |
Section VI. microRNA annotation
miRNA family | Target position | miRNA ID | miRNA seq | ||
---|---|---|---|---|---|
UTR start | UTR end | Match method | |||
miR-138 | 211 | 217 | m8 | hsa-miR-138brain | AGCUGGUGUUGUGAAUC |
miR-15/16/195/424/497 | 247 | 254 | 1A,m8 | hsa-miR-15abrain | UAGCAGCACAUAAUGGUUUGUG |
hsa-miR-16brain | UAGCAGCACGUAAAUAUUGGCG | ||||
hsa-miR-15bbrain | UAGCAGCACAUCAUGGUUUACA | ||||
hsa-miR-195SZ | UAGCAGCACAGAAAUAUUGGC | ||||
hsa-miR-424 | CAGCAGCAAUUCAUGUUUUGAA | ||||
hsa-miR-497 | CAGCAGCACACUGUGGUUUGU | ||||
hsa-miR-15abrain | UAGCAGCACAUAAUGGUUUGUG | ||||
hsa-miR-16brain | UAGCAGCACGUAAAUAUUGGCG | ||||
hsa-miR-15bbrain | UAGCAGCACAUCAUGGUUUACA | ||||
hsa-miR-195SZ | UAGCAGCACAGAAAUAUUGGC | ||||
hsa-miR-424 | CAGCAGCAAUUCAUGUUUUGAA | ||||
hsa-miR-497 | CAGCAGCACACUGUGGUUUGU | ||||
miR-26 | 265 | 271 | m8 | hsa-miR-26abrain | UUCAAGUAAUCCAGGAUAGGC |
hsa-miR-26bSZ | UUCAAGUAAUUCAGGAUAGGUU | ||||
miR-503 | 486 | 492 | 1A | hsa-miR-503 | UAGCAGCGGGAACAGUUCUGCAG |
hsa-miR-503 | UAGCAGCGGGAACAGUUCUGCAG | ||||
miR-9 | 18 | 25 | 1A,m8 | hsa-miR-9SZ | UCUUUGGUUAUCUAGCUGUAUGA |
- SZ: miRNAs which differentially expressed in brain cortex of schizophrenia patients comparing with control samples using microarray. Click here to see the list of SZ related miRNAs.
- Brain: miRNAs which are expressed in brain based on miRNA microarray expression studies. Click here to see the list of brain related miRNAs.