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Gene Page: PIK3R1

Summary

GeneID

5295

Symbol

PIK3R1

Synonyms

GRB1|p85|p85-ALPHA

Description

phosphoinositide-3-kinase, regulatory subunit 1 (alpha)

Locus tag

Gene type

protein-coding

Map location

5q13.1

Gene in Data Sources

Gene set name

Method of gene set

Evidence

Info

Network

Shortest path distance of core genes in the Human protein-protein interaction network

Contribution to shortest path in PPI network: 9.9284

General Gene Expression (microarray) ?

Gene Expression in Brain Regions (new)

Top co-expressed genes in Brain Regions (new)

Gene

Pearson's Correlation

Spearman's Correlation

Top 10 positively co-expressed genes

SLCO2B1

0.76

0.81

LAMB2

0.74

0.75

MMRN2

0.72

0.78

TGM2

0.71

0.79

SNX33

0.71

0.76

TLN1

0.70

0.74

ENG

0.69

0.74

TGFBR2

0.68

0.75

A2M

0.68

0.74

ANGPTL2

0.68

0.75

Top 10 negatively co-expressed genes

OXSM

-0.48

-0.55

NDUFAF2

-0.46

-0.54

COMMD3

-0.45

-0.54

COQ3

-0.44

-0.50

ZNF32

-0.44

-0.54

SNHG12

-0.43

-0.50

C12orf45

-0.43

-0.54

FAM92A1

-0.43

-0.47

SLC10A5

-0.42

-0.44

GPR22

-0.42

Gene Ontology

Molecular function

GO term

Evidence

Neuro keywords

PubMed ID

GO:0005159

insulin-like growth factor receptor binding

IPI

7541045

GO:0005158

insulin receptor binding

IPI

7537849 |8276809

GO:0005545

phosphatidylinositol binding

NAS

GO:0035014

phosphoinositide 3-kinase regulator activity

ISS

GO:0019903

protein phosphatase binding

IPI

14699157

GO:0043125

ErbB-3 class receptor binding

IDA

10572067

GO:0043559

insulin binding

IDA

8440175

GO:0043560

insulin receptor substrate binding

ISS

Biological process

GO term

Evidence

Neuro keywords

PubMed ID

GO:0007242

intracellular signaling cascade

NAS

GO:0008286

insulin receptor signaling pathway

IPI

8276809

GO:0048009

insulin-like growth factor receptor signaling pathway

IPI

7541045

GO:0046854

phosphoinositide phosphorylation

ISS

GO:0044419

interspecies interaction between organisms

IEA

Cellular component

GO term

Evidence

Neuro keywords

PubMed ID

GO:0005829

cytosol

EXP

9356464 |10648629 |11606067
|12167717 |12660731

GO:0005622

intracellular

IEA

GO:0005737

cytoplasm

IDA

18029348

GO:0005943

1-phosphatidylinositol-4-phosphate 3-kinase, class IA complex

ISS

Protein-protein Interactions

Shown by network

Interactors	Aliases B	Official full name B	Experimental	Source	PubMed ID
ABL1	ABL \| JTK7 \| bcr/abl \| c-ABL \| p150 \| v-abl	c-abl oncogene 1, receptor tyrosine kinase	c-Abl interacts with p85. This interaction was modeled on a demonstrated interaction between human c-Abl and bovine p85.	BIND	1383690
ABL1	ABL \| JTK7 \| bcr/abl \| c-ABL \| p150 \| v-abl	c-abl oncogene 1, receptor tyrosine kinase	Reconstituted Complex	BioGRID	8294442
ADAM12	MCMP \| MCMPMltna \| MLTN \| MLTNA	ADAM metallopeptidase domain 12	-	HPRD,BioGRID	11313349
AGAP2	CENTG1 \| FLJ16430 \| GGAP2 \| KIAA0167 \| PIKE	ArfGAP with GTPase domain, ankyrin repeat and PH domain 2	-	HPRD,BioGRID	11136977
ARAF	A-RAF \| ARAF1 \| PKS2 \| RAFA1	v-raf murine sarcoma 3611 viral oncogene homolog	-	HPRD,BioGRID	11812000
ARHGAP1	CDC42GAP \| RHOGAP \| RHOGAP1 \| p50rhoGAP	Rho GTPase activating protein 1	-	HPRD,BioGRID	8253717
ARHGAP17	DKFZp564A1363 \| FLJ37567 \| FLJ43368 \| MGC87805 \| MST066 \| MST110 \| MSTP038 \| MSTP066 \| MSTP110 \| NADRIN \| RICH1 \| WBP15	Rho GTPase activating protein 17	Reconstituted Complex	BioGRID	11431473
AXL	JTK11 \| UFO	AXL receptor tyrosine kinase	Biochemical Activity	BioGRID	9178760
AXL	JTK11 \| UFO	AXL receptor tyrosine kinase	Axl interacts with an unspecified isoform of p85-alpha.	BIND	12470648
BCAR1	CAS \| CAS1 \| CASS1 \| CRKAS \| P130Cas	breast cancer anti-estrogen resistance 1	-	HPRD,BioGRID	10799562
CBL	C-CBL \| CBL2 \| RNF55	Cas-Br-M (murine) ecotropic retroviral transforming sequence	Affinity Capture-Western	BioGRID	9461587 \|9918857
CBLB	DKFZp686J10223 \| DKFZp779A0729 \| DKFZp779F1443 \| FLJ36865 \| FLJ41152 \| Nbla00127 \| RNF56	Cas-Br-M (murine) ecotropic retroviral transforming sequence b	Affinity Capture-Western	BioGRID	9614102
CD19	B4 \| MGC12802	CD19 molecule	-	HPRD	7528218
CD22	FLJ22814 \| MGC130020 \| SIGLEC-2 \| SIGLEC2	CD22 molecule	-	HPRD	8647200
CD28	MGC138290 \| Tp44	CD28 molecule	-	HPRD,BioGRID	7737275 \|8621607
CD2AP	CMS \| DKFZp586H0519	CD2-associated protein	-	HPRD	10339567
CD3E	FLJ18683 \| T3E \| TCRE	CD3e molecule, epsilon (CD3-TCR complex)	-	HPRD,BioGRID	9312149 \|11689561 \|11855827
CD4	CD4mut	CD4 molecule	-	HPRD	8246987
CD5	LEU1 \| T1	CD5 molecule	-	HPRD,BioGRID	9079809
CD7	GP40 \| LEU-9 \| TP41 \| Tp40	CD7 molecule	-	HPRD,BioGRID	8918688
CDC42	CDC42Hs \| G25K	cell division cycle 42 (GTP binding protein, 25kDa)	-	HPRD,BioGRID	7629060 \|8034624 \|9381982
CDC42	CDC42Hs \| G25K	cell division cycle 42 (GTP binding protein, 25kDa)	-	HPRD	9381982
CHRNA7	CHRNA7-2 \| NACHRA7	cholinergic receptor, nicotinic, alpha 7	-	HPRD	11278378
CRKL	-	v-crk sarcoma virus CT10 oncogene homolog (avian)-like	Affinity Capture-Western	BioGRID	9461587
CSF1R	C-FMS \| CD115 \| CSFR \| FIM2 \| FMS	colony stimulating factor 1 receptor	-	HPRD,BioGRID	8947469
CSF1R	C-FMS \| CD115 \| CSFR \| FIM2 \| FMS	colony stimulating factor 1 receptor	CSF1R (c-FMS) interacts with PIK3R1 (PI3'-k).his interaction was modeled on a demonstrated interaction between CSF1R and PIK3R1 from unspecified species.	BIND	15735664
CSF2RA	CD116 \| CDw116 \| CSF2R \| CSF2RAX \| CSF2RAY \| CSF2RX \| CSF2RY \| GM-CSF-R-alpha \| GMCSFR \| GMR \| MGC3848 \| MGC4838	colony stimulating factor 2 receptor, alpha, low-affinity (granulocyte-macrophage)	-	HPRD,BioGRID	12538575
CTLA4	CD152 \| CELIAC3 \| CTLA-4 \| GSE \| IDDM12	cytotoxic T-lymphocyte-associated protein 4	-	HPRD	7807015
CTNNB1	CTNNB \| DKFZp686D02253 \| FLJ25606 \| FLJ37923	catenin (cadherin-associated protein), beta 1, 88kDa	Reconstituted Complex	BioGRID	10477752
CTNNB1	CTNNB \| DKFZp686D02253 \| FLJ25606 \| FLJ37923	catenin (cadherin-associated protein), beta 1, 88kDa	-	HPRD	11716761
DOK1	MGC117395 \| MGC138860 \| P62DOK	docking protein 1, 62kDa (downstream of tyrosine kinase 1)	Reconstituted Complex	BioGRID	11071635
EGFR	ERBB \| ERBB1 \| HER1 \| PIG61 \| mENA	epidermal growth factor receptor (erythroblastic leukemia viral (v-erb-b) oncogene homolog, avian)	-	HPRD	8662998
EGFR	ERBB \| ERBB1 \| HER1 \| PIG61 \| mENA		EGFR interacts with p85. This interaction was modeled on a demonstrated interaction between human EGFR and bovine p85.	BIND	1372092
EPHA2	ECK	EPH receptor A2	Affinity Capture-Western Reconstituted Complex Two-hybrid	BioGRID	7982920
EPOR	MGC138358	erythropoietin receptor	-	HPRD,BioGRID	7559499
ERAS	HRAS2 \| HRASP \| MGC126691 \| MGC126693	ES cell expressed Ras	-	HPRD	12774123
ERBB2	CD340 \| HER-2 \| HER-2/neu \| HER2 \| NEU \| NGL \| TKR1	v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian)	-	HPRD	1351056
ERBB3	ErbB-3 \| HER3 \| LCCS2 \| MDA-BF-1 \| MGC88033 \| c-erbB-3 \| c-erbB3 \| erbB3-S \| p180-ErbB3 \| p45-sErbB3 \| p85-sErbB3	v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian)	-	HPRD,BioGRID	10383151 \|11546794
ESR1	DKFZp686N23123 \| ER \| ESR \| ESRA \| Era \| NR3A1	estrogen receptor 1	-	HPRD,BioGRID	11689445
EZR	CVIL \| CVL \| DKFZp762H157 \| FLJ26216 \| MGC1584 \| VIL2	ezrin	-	HPRD,BioGRID	10377409
FASLG	APT1LG1 \| CD178 \| CD95L \| FASL \| TNFSF6	Fas ligand (TNF superfamily, member 6)	-	HPRD	11741599
FCGR2A	CD32 \| CD32A \| CDw32 \| FCG2 \| FCGR2 \| FCGR2A1 \| FcGR \| IGFR2 \| MGC23887 \| MGC30032	Fc fragment of IgG, low affinity IIa, receptor (CD32)	-	HPRD,BioGRID	8631888
FES	FPS	feline sarcoma oncogene	-	HPRD,BioGRID	8916957
FLT1	FLT \| VEGFR1	fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor)	Flt-1 interacts with p85.	BIND	7657594
FYN	MGC45350 \| SLK \| SYN	FYN oncogene related to SRC, FGR, YES	-	HPRD	8394019
FYN	MGC45350 \| SLK \| SYN	FYN oncogene related to SRC, FGR, YES	Reconstituted Complex	BioGRID	8294442
GAB1	-	GRB2-associated binding protein 1	Affinity Capture-Western Far Western Reconstituted Complex	BioGRID	8596638 \|9891995
GAB2	KIAA0571	GRB2-associated binding protein 2	Affinity Capture-Western Two-hybrid	BioGRID	11334882 \|11782427
GAB2	KIAA0571	GRB2-associated binding protein 2	-	HPRD	10068651
GAB3	-	GRB2-associated binding protein 3	-	HPRD	11739737
GHR	GHBP	growth hormone receptor	-	HPRD,BioGRID	9632636
GNAQ	G-ALPHA-q \| GAQ	guanine nucleotide binding protein (G protein), q polypeptide	Affinity Capture-Western	BioGRID	12704201
GRB2	ASH \| EGFRBP-GRB2 \| Grb3-3 \| MST084 \| MSTP084	growth factor receptor-bound protein 2	p85 interacts with Grb2.	BIND	8662998
GRB2	ASH \| EGFRBP-GRB2 \| Grb3-3 \| MST084 \| MSTP084	growth factor receptor-bound protein 2	-	HPRD,BioGRID	7642542 \|7737969 \|7759531
HCST	DAP10 \| DKFZP586C1522 \| KAP10 \| PIK3AP	hematopoietic cell signal transducer	Protein-peptide	BioGRID	10426994
HGS	HRS \| ZFYVE8	hepatocyte growth factor-regulated tyrosine kinase substrate	-	HPRD	10970851
HNRNPK	CSBP \| FLJ41122 \| HNRPK \| TUNP	heterogeneous nuclear ribonucleoprotein K	p85 interacts with hnRNPK. This interaction was modeled on a demonstrated interaction between p85 from an unspecified source and human hnRNPK.	BIND	8810341
HRAS	C-BAS/HAS \| C-H-RAS \| C-HA-RAS1 \| CTLO \| H-RASIDX \| HAMSV \| HRAS1 \| K-RAS \| N-RAS \| RASH1	v-Ha-ras Harvey rat sarcoma viral oncogene homolog	-	HPRD,BioGRID	10212255
IFNAR1	AVP \| IFN-alpha-REC \| IFNAR \| IFNBR \| IFRC	interferon (alpha, beta and omega) receptor 1	-	HPRD,BioGRID	10542297
IGF1R	CD221 \| IGFIR \| JTK13 \| MGC142170 \| MGC142172 \| MGC18216	insulin-like growth factor 1 receptor	-	HPRD,BioGRID	8697095
IL13	ALRH \| BHR1 \| IL-13 \| MGC116786 \| MGC116788 \| MGC116789 \| P600	interleukin 13	-	HPRD	9139718
IL1R1	CD121A \| D2S1473 \| IL-1R-alpha \| IL1R \| IL1RA \| P80	interleukin 1 receptor, type I	-	HPRD,BioGRID	9360994 \|10373529
IL1RAP	C3orf13 \| FLJ37788 \| IL-1RAcP \| IL1R3	interleukin 1 receptor accessory protein	-	HPRD,BioGRID	10373529
IL2RB	CD122 \| P70-75	interleukin 2 receptor, beta	-	HPRD,BioGRID	9774657
IL6ST	CD130 \| CDw130 \| GP130 \| GP130-RAPS \| IL6R-beta	interleukin 6 signal transducer (gp130, oncostatin M receptor)	Affinity Capture-Western	BioGRID	10579793
INPP5D	MGC104855 \| MGC142140 \| MGC142142 \| SHIP \| SHIP1 \| SIP-145 \| hp51CN	inositol polyphosphate-5-phosphatase, 145kDa	Affinity Capture-Western	BioGRID	9918857
INSR	CD220 \| HHF5	insulin receptor	INSR (IR) interacts with PIK3R1. This interaction was modeled on a demonstrated interaction between INSR and PIK3R1 from unspecified species.	BIND	15735664
INSR	CD220 \| HHF5	insulin receptor	The insulin receptor (IR) interacts with p85-alpha.	BIND	8603569
IRS1	HIRS-1	insulin receptor substrate 1	Affinity Capture-Western Far Western	BioGRID	1381348 \|12107746 \|12173038 \|12730242
			-	HPRD	1381348 \|12173038
			-	HPRD	12220227
IRS2	-	insulin receptor substrate 2	-	HPRD,BioGRID	9852124 \|12107746
IRS4	IRS-4 \| PY160	insulin receptor substrate 4	-	HPRD	11912194
JAK1	JAK1A \| JAK1B \| JTK3	Janus kinase 1 (a protein tyrosine kinase)	-	HPRD,BioGRID	9774657
JAK2	JTK10	Janus kinase 2 (a protein tyrosine kinase)	-	HPRD,BioGRID	8702385
KHDRBS1	FLJ34027 \| Sam68 \| p62	KH domain containing, RNA binding, signal transduction associated 1	Affinity Capture-Western Reconstituted Complex	BioGRID	10467411 \|11604231
KHDRBS1	FLJ34027 \| Sam68 \| p62		Sam68 interacts with the SH2 domains of PI3K p85 alpha. This interaction was modelled based on a demonstrated interaction between two rat proteins.	BIND	7537265 \|10437794 \|11604231
KIT	C-Kit \| CD117 \| PBT \| SCFR	v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog	Kit interacts with p85-alpha. This interaction was modeled on a demonstrated interaction between mouse proteins	BIND	10022833
KIT	C-Kit \| CD117 \| PBT \| SCFR		-	HPRD,BioGRID	7509796
LAT	LAT1 \| pp36	linker for activation of T cells	Affinity Capture-Western Reconstituted Complex	BioGRID	11368773
LCK	YT16 \| p56lck \| pp58lck	lymphocyte-specific protein tyrosine kinase	-	HPRD	7504174
LCK	YT16 \| p56lck \| pp58lck	lymphocyte-specific protein tyrosine kinase	Reconstituted Complex	BioGRID	8294442
LCP2	SLP-76 \| SLP76	lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa)	Affinity Capture-Western Two-hybrid	BioGRID	15388330
MET	AUTS9 \| HGFR \| RCCP2 \| c-Met	met proto-oncogene (hepatocyte growth factor receptor)	MET (c-Met) interacts with PIK3R1. This interaction was modeled on a demonstrated interaction between human c-Met and PIK3R1 from an unspecified species.	BIND	15735664
MME	CALLA \| CD10 \| DKFZp686O16152 \| MGC126681 \| MGC126707 \| NEP	membrane metallo-endopeptidase	-	HPRD	12529960
MST1R	CD136 \| CDw136 \| PTK8 \| RON	macrophage stimulating 1 receptor (c-met-related tyrosine kinase)	-	HPRD	8918464
NFKBIA	IKBA \| MAD-3 \| NFKBI	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha	-	HPRD,BioGRID	9892650
NTRK2	GP145-TrkB \| TRKB	neurotrophic tyrosine kinase, receptor, type 2	Two-hybrid	BioGRID	12074588
PDGFRB	CD140B \| JTK12 \| PDGF-R-beta \| PDGFR \| PDGFR1	platelet-derived growth factor receptor, beta polypeptide	in vivo	BioGRID	10697503
			Beta-PDGFR interacts with p85. This interaction was modeled on a demonstrated interaction between human beta-PDGFR and rat or bovine p85.	BIND	1372092 \|7689724 \|7876130
			Phosphorylated beta-PDGFR interacts with p85-alpha. This interaction was modeled on a demonstrated interaction between human beta-PDGFR and bovine p85-alpha.	BIND	8388538
PECAM1	CD31 \| PECAM-1	platelet/endothelial cell adhesion molecule	Affinity Capture-Western	BioGRID	9774384
PIK3CA	MGC142161 \| MGC142163 \| PI3K \| p110-alpha	phosphoinositide-3-kinase, catalytic, alpha polypeptide	Reconstituted Complex	BioGRID	7929193
PIK3CB	DKFZp779K1237 \| MGC133043 \| PI3K \| PI3KCB \| PI3Kbeta \| PIK3C1 \| p110-BETA	phosphoinositide-3-kinase, catalytic, beta polypeptide	-	HPRD,BioGRID	8139559 \|10358930
PIK3CD	p110D	phosphoinositide-3-kinase, catalytic, delta polypeptide	-	HPRD,BioGRID	9113989
PIK3R1	GRB1 \| p85 \| p85-ALPHA	phosphoinositide-3-kinase, regulatory subunit 1 (alpha)	Reconstituted Complex	BioGRID	8294442
PTK2	FADK \| FAK \| FAK1 \| pp125FAK	PTK2 protein tyrosine kinase 2	-	HPRD,BioGRID	7537275 \|8649427 \|10806474
PTK2B	CADTK \| CAKB \| FADK2 \| FAK2 \| FRNK \| PKB \| PTK \| PYK2 \| RAFTK	PTK2B protein tyrosine kinase 2 beta	-	HPRD	10797305
PTPN11	BPTP3 \| CFC \| MGC14433 \| NS1 \| PTP-1D \| PTP2C \| SH-PTP2 \| SH-PTP3 \| SHP2	protein tyrosine phosphatase, non-receptor type 11	Affinity Capture-Western	BioGRID	9918857
PTPN6	HCP \| HCPH \| HPTP1C \| PTP-1C \| SH-PTP1 \| SHP-1 \| SHP-1L \| SHP1	protein tyrosine phosphatase, non-receptor type 6	Two-hybrid	BioGRID	11160222
PTPN6		protein tyrosine phosphatase, non-receptor type 6	-	HPRD	11337495
PXN	FLJ16691	paxillin	Co-purification	BioGRID	8641358
RAC1	MGC111543 \| MIG5 \| TC-25 \| p21-Rac1	ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)	-	HPRD	7629060 \|8034624 \|12086876
RAC1	MGC111543 \| MIG5 \| TC-25 \| p21-Rac1		-	HPRD	12086876
RASA1	CM-AVM \| CMAVM \| DKFZp434N071 \| GAP \| PKWS \| RASA \| RASGAP \| p120GAP \| p120RASGAP	RAS p21 protein activator (GTPase activating protein) 1	-	HPRD	1336372
RB1	OSRC \| RB \| p105-Rb \| pRb \| pp110	retinoblastoma 1	Rb interacts with p55alpha	BIND	12588990
RET	CDHF12 \| HSCR1 \| MEN2A \| MEN2B \| MTC1 \| PTC \| RET-ELE1 \| RET51	ret proto-oncogene	-	HPRD	10652352
RICS	GC-GAP \| GRIT \| KIAA0712 \| MGC1892 \| p200RhoGAP \| p250GAP	Rho GTPase-activating protein	-	HPRD,BioGRID	12454018
RRAS2	TC21	related RAS viral (r-ras) oncogene homolog 2	-	HPRD,BioGRID	11850823
SH3KBP1	CIN85 \| GIG10 \| MIG18	SH3-domain kinase binding protein 1	-	HPRD,BioGRID	10921882
SHB	RP11-3J10.8 \| bA3J10.2	Src homology 2 domain containing adaptor protein B	Shb interacts with p85-alpha PI3 kinase. This interaction was modelled on a demonstrated interaction between human Shb and bovine p85-alpha PI3 kinase.	BIND	7537362
SHB	RP11-3J10.8 \| bA3J10.2	Src homology 2 domain containing adaptor protein B	-	HPRD,BioGRID	7537362
SHC1	FLJ26504 \| SHC \| SHCA	SHC (Src homology 2 domain containing) transforming protein 1	Reconstituted Complex	BioGRID	7537361
			p85 interacts with Shc.	BIND	8662998
			-	HPRD	8662998
SLC9A2	NHE2	solute carrier family 9 (sodium/hydrogen exchanger), member 2	-	HPRD	10187839
SRC	ASV \| SRC1 \| c-SRC \| p60-Src	v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian)	-	HPRD	12210743
SRC	ASV \| SRC1 \| c-SRC \| p60-Src		Affinity Capture-Western	BioGRID	10487518
SYN1	SYN1a \| SYN1b \| SYNI	synapsin I	-	HPRD,BioGRID	10899172
TEK	CD202B \| TIE-2 \| TIE2 \| VMCM \| VMCM1	TEK tyrosine kinase, endothelial	-	HPRD	10521483
TGFBR1	AAT5 \| ACVRLK4 \| ALK-5 \| ALK5 \| LDS1A \| LDS2A \| SKR4 \| TGFR-1	transforming growth factor, beta receptor 1	-	HPRD,BioGRID	9435577
TGFBR2	AAT3 \| FAA3 \| LDS1B \| LDS2B \| MFS2 \| RIIC \| TAAD2 \| TGFR-2 \| TGFbeta-RII	transforming growth factor, beta receptor II (70/80kDa)	Affinity Capture-Western	BioGRID	9435577
TIE1	JTK14 \| TIE	tyrosine kinase with immunoglobulin-like and EGF-like domains 1	-	HPRD	11865050
TLN1	ILWEQ \| KIAA1027 \| TLN	talin 1	Co-purification	BioGRID	8641358
TOM1L1	OK/KNS-CL.3 \| SRCASM	target of myb1 (chicken)-like 1	-	HPRD	11711534
TRAT1	HSPC062 \| TCRIM \| TRIM	T cell receptor associated transmembrane adaptor 1	-	HPRD	10723796
TUBA1B	K-ALPHA-1	tubulin, alpha 1b	-	HPRD,BioGRID	7592789
TUBG1	TUBG \| TUBGCP1	tubulin, gamma 1	-	HPRD	7592789
TYRO3	BYK \| Brt \| Dtk \| FLJ16467 \| RSE \| Sky \| Tif	TYRO3 protein tyrosine kinase	-	HPRD,BioGRID	10627473
VAV1	VAV	vav 1 guanine nucleotide exchange factor	-	HPRD	7528218 \|9891995
VAV1	VAV	vav 1 guanine nucleotide exchange factor	Affinity Capture-Western Reconstituted Complex	BioGRID	9162069 \|9891995
VAV3	FLJ40431	vav 3 guanine nucleotide exchange factor	-	HPRD	11094073
WAS	IMD2 \| THC \| WASP	Wiskott-Aldrich syndrome (eczema-thrombocytopenia)	Affinity Capture-Western Reconstituted Complex	BioGRID	8805332
WAS	IMD2 \| THC \| WASP	Wiskott-Aldrich syndrome (eczema-thrombocytopenia)	-	HPRD	10358777
WBP11	DKFZp779M1063 \| NPWBP \| SIPP1	WW domain binding protein 11	-	HPRD	11375989

Pathway annotation

Pathway name	Pathway size	# SZGR genes in pathway	Info
KEGG_ERBB_SIGNALING_PATHWAY	87	71	All SZGR genes in this pathway
KEGG_CHEMOKINE_SIGNALING_PATHWAY	190	128	All SZGR genes in this pathway
KEGG_PHOSPHATIDYLINOSITOL_SIGNALING_SYSTEM	76	56	All SZGR genes in this pathway
KEGG_MTOR_SIGNALING_PATHWAY	52	40	All SZGR genes in this pathway
KEGG_APOPTOSIS	88	62	All SZGR genes in this pathway
KEGG_VEGF_SIGNALING_PATHWAY	76	53	All SZGR genes in this pathway
KEGG_FOCAL_ADHESION	201	138	All SZGR genes in this pathway
KEGG_TOLL_LIKE_RECEPTOR_SIGNALING_PATHWAY	102	88	All SZGR genes in this pathway
KEGG_JAK_STAT_SIGNALING_PATHWAY	155	105	All SZGR genes in this pathway
KEGG_NATURAL_KILLER_CELL_MEDIATED_CYTOTOXICITY	137	92	All SZGR genes in this pathway
KEGG_T_CELL_RECEPTOR_SIGNALING_PATHWAY	108	89	All SZGR genes in this pathway
KEGG_B_CELL_RECEPTOR_SIGNALING_PATHWAY	75	56	All SZGR genes in this pathway
KEGG_FC_EPSILON_RI_SIGNALING_PATHWAY	79	58	All SZGR genes in this pathway
KEGG_FC_GAMMA_R_MEDIATED_PHAGOCYTOSIS	97	71	All SZGR genes in this pathway
KEGG_LEUKOCYTE_TRANSENDOTHELIAL_MIGRATION	118	78	All SZGR genes in this pathway
KEGG_NEUROTROPHIN_SIGNALING_PATHWAY	126	103	All SZGR genes in this pathway
KEGG_REGULATION_OF_ACTIN_CYTOSKELETON	216	144	All SZGR genes in this pathway
KEGG_INSULIN_SIGNALING_PATHWAY	137	103	All SZGR genes in this pathway
KEGG_PROGESTERONE_MEDIATED_OOCYTE_MATURATION	86	59	All SZGR genes in this pathway
KEGG_TYPE_II_DIABETES_MELLITUS	47	41	All SZGR genes in this pathway
KEGG_ALDOSTERONE_REGULATED_SODIUM_REABSORPTION	42	29	All SZGR genes in this pathway
KEGG_PATHWAYS_IN_CANCER	328	259	All SZGR genes in this pathway
KEGG_COLORECTAL_CANCER	62	47	All SZGR genes in this pathway
KEGG_RENAL_CELL_CARCINOMA	70	60	All SZGR genes in this pathway
KEGG_PANCREATIC_CANCER	70	56	All SZGR genes in this pathway
KEGG_ENDOMETRIAL_CANCER	52	45	All SZGR genes in this pathway
KEGG_GLIOMA	65	56	All SZGR genes in this pathway
KEGG_PROSTATE_CANCER	89	75	All SZGR genes in this pathway
KEGG_MELANOMA	71	57	All SZGR genes in this pathway
KEGG_CHRONIC_MYELOID_LEUKEMIA	73	59	All SZGR genes in this pathway
KEGG_ACUTE_MYELOID_LEUKEMIA	60	47	All SZGR genes in this pathway
KEGG_SMALL_CELL_LUNG_CANCER	84	67	All SZGR genes in this pathway
KEGG_NON_SMALL_CELL_LUNG_CANCER	54	47	All SZGR genes in this pathway
BIOCARTA_AKT_PATHWAY	22	16	All SZGR genes in this pathway
BIOCARTA_BCELLSURVIVAL_PATHWAY	16	10	All SZGR genes in this pathway
BIOCARTA_HDAC_PATHWAY	32	25	All SZGR genes in this pathway
BIOCARTA_GCR_PATHWAY	22	17	All SZGR genes in this pathway
BIOCARTA_CTCF_PATHWAY	23	18	All SZGR genes in this pathway
BIOCARTA_CXCR4_PATHWAY	24	22	All SZGR genes in this pathway
BIOCARTA_EGF_PATHWAY	31	25	All SZGR genes in this pathway
BIOCARTA_ECM_PATHWAY	24	17	All SZGR genes in this pathway
BIOCARTA_FCER1_PATHWAY	41	30	All SZGR genes in this pathway
BIOCARTA_GH_PATHWAY	28	22	All SZGR genes in this pathway
BIOCARTA_HCMV_PATHWAY	17	16	All SZGR genes in this pathway
BIOCARTA_IGF1_PATHWAY	21	16	All SZGR genes in this pathway
BIOCARTA_IL2RB_PATHWAY	38	26	All SZGR genes in this pathway
BIOCARTA_IL7_PATHWAY	17	14	All SZGR genes in this pathway
BIOCARTA_GSK3_PATHWAY	27	26	All SZGR genes in this pathway
BIOCARTA_RACCYCD_PATHWAY	26	23	All SZGR genes in this pathway
BIOCARTA_GLEEVEC_PATHWAY	23	17	All SZGR genes in this pathway
BIOCARTA_INSULIN_PATHWAY	22	16	All SZGR genes in this pathway
BIOCARTA_PPARA_PATHWAY	58	43	All SZGR genes in this pathway
BIOCARTA_MTOR_PATHWAY	23	15	All SZGR genes in this pathway
BIOCARTA_IGF1R_PATHWAY	23	20	All SZGR genes in this pathway
BIOCARTA_NGF_PATHWAY	18	13	All SZGR genes in this pathway
BIOCARTA_NFAT_PATHWAY	56	45	All SZGR genes in this pathway
BIOCARTA_PDGF_PATHWAY	32	25	All SZGR genes in this pathway
BIOCARTA_EDG1_PATHWAY	27	24	All SZGR genes in this pathway
BIOCARTA_PTEN_PATHWAY	18	14	All SZGR genes in this pathway
BIOCARTA_RAC1_PATHWAY	23	16	All SZGR genes in this pathway
BIOCARTA_RAS_PATHWAY	23	20	All SZGR genes in this pathway
BIOCARTA_NKCELLS_PATHWAY	20	13	All SZGR genes in this pathway
BIOCARTA_BAD_PATHWAY	26	23	All SZGR genes in this pathway
BIOCARTA_EIF4_PATHWAY	24	19	All SZGR genes in this pathway
BIOCARTA_HER2_PATHWAY	22	17	All SZGR genes in this pathway
BIOCARTA_ERK5_PATHWAY	18	15	All SZGR genes in this pathway
BIOCARTA_ACH_PATHWAY	16	13	All SZGR genes in this pathway
BIOCARTA_CDC42RAC_PATHWAY	16	13	All SZGR genes in this pathway
BIOCARTA_MET_PATHWAY	37	30	All SZGR genes in this pathway
BIOCARTA_IGF1MTOR_PATHWAY	20	14	All SZGR genes in this pathway
BIOCARTA_TCR_PATHWAY	49	37	All SZGR genes in this pathway
BIOCARTA_CTLA4_PATHWAY	21	18	All SZGR genes in this pathway
BIOCARTA_LONGEVITY_PATHWAY	15	13	All SZGR genes in this pathway
BIOCARTA_PAR1_PATHWAY	37	28	All SZGR genes in this pathway
BIOCARTA_TPO_PATHWAY	24	17	All SZGR genes in this pathway
BIOCARTA_CREB_PATHWAY	27	25	All SZGR genes in this pathway
BIOCARTA_TFF_PATHWAY	21	15	All SZGR genes in this pathway
BIOCARTA_TRKA_PATHWAY	12	10	All SZGR genes in this pathway
BIOCARTA_ARF_PATHWAY	17	13	All SZGR genes in this pathway
BIOCARTA_VEGF_PATHWAY	29	18	All SZGR genes in this pathway
ST_DIFFERENTIATION_PATHWAY_IN_PC12_CELLS	45	35	All SZGR genes in this pathway
SIG_CD40PATHWAYMAP	34	28	All SZGR genes in this pathway
SIG_CHEMOTAXIS	45	37	All SZGR genes in this pathway
SIG_IL4RECEPTOR_IN_B_LYPHOCYTES	27	23	All SZGR genes in this pathway
ST_ADRENERGIC	36	29	All SZGR genes in this pathway
SIG_INSULIN_RECEPTOR_PATHWAY_IN_CARDIAC_MYOCYTES	51	41	All SZGR genes in this pathway
SIG_BCR_SIGNALING_PATHWAY	46	38	All SZGR genes in this pathway
ST_B_CELL_ANTIGEN_RECEPTOR	40	32	All SZGR genes in this pathway
PID_FCER1_PATHWAY	62	43	All SZGR genes in this pathway
PID_BCR_5PATHWAY	65	50	All SZGR genes in this pathway
PID_ERBB4_PATHWAY	38	32	All SZGR genes in this pathway
PID_LYSOPHOSPHOLIPID_PATHWAY	66	53	All SZGR genes in this pathway
PID_INSULIN_PATHWAY	45	32	All SZGR genes in this pathway
PID_GMCSF_PATHWAY	37	31	All SZGR genes in this pathway
PID_NFKAPPAB_ATYPICAL_PATHWAY	17	15	All SZGR genes in this pathway
PID_IL4_2PATHWAY	65	43	All SZGR genes in this pathway
PID_ER_NONGENOMIC_PATHWAY	41	35	All SZGR genes in this pathway
PID_MET_PATHWAY	80	60	All SZGR genes in this pathway
PID_PTP1B_PATHWAY	52	40	All SZGR genes in this pathway
PID_EPHB_FWD_PATHWAY	40	38	All SZGR genes in this pathway
PID_AVB3_OPN_PATHWAY	31	29	All SZGR genes in this pathway
PID_REELIN_PATHWAY	29	29	All SZGR genes in this pathway
PID_NECTIN_PATHWAY	30	20	All SZGR genes in this pathway
PID_TRAIL_PATHWAY	28	20	All SZGR genes in this pathway
PID_CDC42_PATHWAY	70	51	All SZGR genes in this pathway
PID_RET_PATHWAY	39	29	All SZGR genes in this pathway
PID_TCPTP_PATHWAY	43	33	All SZGR genes in this pathway
PID_ANGIOPOIETIN_RECEPTOR_PATHWAY	50	41	All SZGR genes in this pathway
PID_FAS_PATHWAY	38	29	All SZGR genes in this pathway
PID_SHP2_PATHWAY	58	46	All SZGR genes in this pathway
PID_NETRIN_PATHWAY	32	27	All SZGR genes in this pathway
PID_IL1_PATHWAY	34	28	All SZGR genes in this pathway
PID_IL2_1PATHWAY	55	43	All SZGR genes in this pathway
PID_CXCR4_PATHWAY	102	78	All SZGR genes in this pathway
PID_IGF1_PATHWAY	30	23	All SZGR genes in this pathway
PID_ERBB1_RECEPTOR_PROXIMAL_PATHWAY	35	29	All SZGR genes in this pathway
PID_IL5_PATHWAY	14	11	All SZGR genes in this pathway
PID_PI3KCI_PATHWAY	49	40	All SZGR genes in this pathway
PID_IL2_PI3K_PATHWAY	34	27	All SZGR genes in this pathway
PID_P75_NTR_PATHWAY	69	51	All SZGR genes in this pathway
PID_ECADHERIN_NASCENT_AJ_PATHWAY	39	33	All SZGR genes in this pathway
PID_AVB3_INTEGRIN_PATHWAY	75	53	All SZGR genes in this pathway
PID_IFNG_PATHWAY	40	34	All SZGR genes in this pathway
PID_ERBB1_DOWNSTREAM_PATHWAY	105	78	All SZGR genes in this pathway
PID_ERBB2_ERBB3_PATHWAY	44	35	All SZGR genes in this pathway
PID_IL3_PATHWAY	27	19	All SZGR genes in this pathway
PID_IL6_7_PATHWAY	47	40	All SZGR genes in this pathway
PID_ECADHERIN_KERATINOCYTE_PATHWAY	21	19	All SZGR genes in this pathway
PID_PDGFRB_PATHWAY	129	103	All SZGR genes in this pathway
PID_TRKR_PATHWAY	62	48	All SZGR genes in this pathway
PID_NEPHRIN_NEPH1_PATHWAY	31	24	All SZGR genes in this pathway
PID_IL23_PATHWAY	37	30	All SZGR genes in this pathway
PID_PDGFRA_PATHWAY	22	18	All SZGR genes in this pathway
PID_HEDGEHOG_2PATHWAY	22	17	All SZGR genes in this pathway
PID_AR_NONGENOMIC_PATHWAY	31	27	All SZGR genes in this pathway
PID_ERBB1_INTERNALIZATION_PATHWAY	41	35	All SZGR genes in this pathway
PID_CXCR3_PATHWAY	43	34	All SZGR genes in this pathway
PID_VEGFR1_PATHWAY	26	23	All SZGR genes in this pathway
PID_KIT_PATHWAY	52	40	All SZGR genes in this pathway
PID_EPO_PATHWAY	34	29	All SZGR genes in this pathway
PID_IL2_STAT5_PATHWAY	30	23	All SZGR genes in this pathway
PID_VEGFR1_2_PATHWAY	69	57	All SZGR genes in this pathway
PID_THROMBIN_PAR1_PATHWAY	43	32	All SZGR genes in this pathway
PID_A6B1_A6B4_INTEGRIN_PATHWAY	46	35	All SZGR genes in this pathway
PID_EPHRINB_REV_PATHWAY	30	25	All SZGR genes in this pathway
PID_NCADHERIN_PATHWAY	33	32	All SZGR genes in this pathway
PID_PI3K_PLC_TRK_PATHWAY	36	31	All SZGR genes in this pathway
PID_EPHA2_FWD_PATHWAY	19	16	All SZGR genes in this pathway
PID_LYMPH_ANGIOGENESIS_PATHWAY	25	16	All SZGR genes in this pathway
PID_FGF_PATHWAY	55	37	All SZGR genes in this pathway
PID_FAK_PATHWAY	59	45	All SZGR genes in this pathway
REACTOME_SIGNALLING_BY_NGF	217	167	All SZGR genes in this pathway
REACTOME_SIGNALING_BY_SCF_KIT	78	59	All SZGR genes in this pathway
REACTOME_CELL_CELL_COMMUNICATION	120	77	All SZGR genes in this pathway
REACTOME_IL_7_SIGNALING	11	9	All SZGR genes in this pathway
REACTOME_SIGNALING_BY_ERBB4	90	67	All SZGR genes in this pathway
REACTOME_SIGNALING_BY_ERBB2	101	78	All SZGR genes in this pathway
REACTOME_SIGNALING_BY_CONSTITUTIVELY_ACTIVE_EGFR	18	13	All SZGR genes in this pathway
REACTOME_SIGNALING_BY_EGFR_IN_CANCER	109	80	All SZGR genes in this pathway
REACTOME_PI3K_EVENTS_IN_ERBB4_SIGNALING	38	28	All SZGR genes in this pathway
REACTOME_PI3K_EVENTS_IN_ERBB2_SIGNALING	44	34	All SZGR genes in this pathway
REACTOME_ANTIGEN_ACTIVATES_B_CELL_RECEPTOR_LEADING_TO_GENERATION_OF_SECOND_MESSENGERS	29	24	All SZGR genes in this pathway
REACTOME_SIGNALING_BY_THE_B_CELL_RECEPTOR_BCR	126	90	All SZGR genes in this pathway
REACTOME_INSULIN_RECEPTOR_SIGNALLING_CASCADE	87	64	All SZGR genes in this pathway
REACTOME_CELL_SURFACE_INTERACTIONS_AT_THE_VASCULAR_WALL	91	65	All SZGR genes in this pathway
REACTOME_NGF_SIGNALLING_VIA_TRKA_FROM_THE_PLASMA_MEMBRANE	137	105	All SZGR genes in this pathway
REACTOME_SIGNALING_BY_FGFR_IN_DISEASE	127	88	All SZGR genes in this pathway
REACTOME_PHOSPHOLIPID_METABOLISM	198	112	All SZGR genes in this pathway
REACTOME_GASTRIN_CREB_SIGNALLING_PATHWAY_VIA_PKC_AND_MAPK	205	136	All SZGR genes in this pathway
REACTOME_SIGNALING_BY_FGFR1_MUTANTS	30	20	All SZGR genes in this pathway
REACTOME_SYNTHESIS_OF_PIPS_AT_THE_PLASMA_MEMBRANE	31	23	All SZGR genes in this pathway
REACTOME_SIGNALING_BY_FGFR1_FUSION_MUTANTS	19	12	All SZGR genes in this pathway
REACTOME_PI_METABOLISM	48	34	All SZGR genes in this pathway
REACTOME_SIGNALING_BY_FGFR_MUTANTS	44	29	All SZGR genes in this pathway
REACTOME_PI3K_AKT_ACTIVATION	38	29	All SZGR genes in this pathway
REACTOME_TCR_SIGNALING	54	46	All SZGR genes in this pathway
REACTOME_DOWNSTREAM_TCR_SIGNALING	37	32	All SZGR genes in this pathway
REACTOME_GAB1_SIGNALOSOME	38	29	All SZGR genes in this pathway
REACTOME_TIE2_SIGNALING	17	13	All SZGR genes in this pathway
REACTOME_SIGNALING_BY_GPCR	920	449	All SZGR genes in this pathway
REACTOME_SIGNALING_BY_PDGF	122	93	All SZGR genes in this pathway
REACTOME_GPVI_MEDIATED_ACTIVATION_CASCADE	31	25	All SZGR genes in this pathway
REACTOME_DOWNSTREAM_SIGNAL_TRANSDUCTION	95	76	All SZGR genes in this pathway
REACTOME_G_ALPHA_Q_SIGNALLING_EVENTS	184	116	All SZGR genes in this pathway
REACTOME_G_ALPHA1213_SIGNALLING_EVENTS	74	56	All SZGR genes in this pathway
REACTOME_CD28_CO_STIMULATION	32	26	All SZGR genes in this pathway
REACTOME_GPCR_DOWNSTREAM_SIGNALING	805	368	All SZGR genes in this pathway
REACTOME_COSTIMULATION_BY_THE_CD28_FAMILY	63	48	All SZGR genes in this pathway
REACTOME_CD28_DEPENDENT_PI3K_AKT_SIGNALING	22	18	All SZGR genes in this pathway
REACTOME_PI_3K_CASCADE	56	39	All SZGR genes in this pathway
REACTOME_DOWNSTREAM_SIGNALING_OF_ACTIVATED_FGFR	100	74	All SZGR genes in this pathway
REACTOME_SIGNALING_BY_ILS	107	86	All SZGR genes in this pathway
REACTOME_METABOLISM_OF_LIPIDS_AND_LIPOPROTEINS	478	302	All SZGR genes in this pathway
REACTOME_REGULATION_OF_SIGNALING_BY_CBL	18	16	All SZGR genes in this pathway
REACTOME_NEPHRIN_INTERACTIONS	20	15	All SZGR genes in this pathway
REACTOME_IL_3_5_AND_GM_CSF_SIGNALING	43	34	All SZGR genes in this pathway
REACTOME_IL_RECEPTOR_SHC_SIGNALING	27	21	All SZGR genes in this pathway
REACTOME_IL_2_SIGNALING	41	34	All SZGR genes in this pathway
REACTOME_SIGNALING_BY_INSULIN_RECEPTOR	108	72	All SZGR genes in this pathway
REACTOME_HEMOSTASIS	466	331	All SZGR genes in this pathway
REACTOME_IMMUNE_SYSTEM	933	616	All SZGR genes in this pathway
REACTOME_ADAPTIVE_IMMUNE_SYSTEM	539	350	All SZGR genes in this pathway
REACTOME_CYTOKINE_SIGNALING_IN_IMMUNE_SYSTEM	270	204	All SZGR genes in this pathway
REACTOME_PLATELET_ACTIVATION_SIGNALING_AND_AGGREGATION	208	138	All SZGR genes in this pathway
REACTOME_SIGNALING_BY_FGFR	112	80	All SZGR genes in this pathway
REACTOME_PI3K_CASCADE	71	51	All SZGR genes in this pathway
LIU_PROSTATE_CANCER_DN	481	290	All SZGR genes in this pathway
ONKEN_UVEAL_MELANOMA_DN	526	357	All SZGR genes in this pathway
ZHOU_INFLAMMATORY_RESPONSE_LIVE_DN	384	220	All SZGR genes in this pathway
DEURIG_T_CELL_PROLYMPHOCYTIC_LEUKEMIA_DN	320	184	All SZGR genes in this pathway
GRABARCZYK_BCL11B_TARGETS_UP	81	40	All SZGR genes in this pathway
BASAKI_YBX1_TARGETS_DN	384	230	All SZGR genes in this pathway
OSMAN_BLADDER_CANCER_UP	404	246	All SZGR genes in this pathway
DITTMER_PTHLH_TARGETS_DN	73	51	All SZGR genes in this pathway
BERENJENO_TRANSFORMED_BY_RHOA_REVERSIBLY_UP	8	6	All SZGR genes in this pathway
LINDGREN_BLADDER_CANCER_CLUSTER_1_UP	121	71	All SZGR genes in this pathway
GRAESSMANN_APOPTOSIS_BY_DOXORUBICIN_DN	1781	1082	All SZGR genes in this pathway
BERENJENO_TRANSFORMED_BY_RHOA_DN	394	258	All SZGR genes in this pathway
MCBRYAN_PUBERTAL_BREAST_6_7WK_UP	197	135	All SZGR genes in this pathway
HU_ANGIOGENESIS_UP	21	16	All SZGR genes in this pathway
RASHI_RESPONSE_TO_IONIZING_RADIATION_5	147	89	All SZGR genes in this pathway
FARMER_BREAST_CANCER_APOCRINE_VS_BASAL	330	217	All SZGR genes in this pathway
HERNANDEZ_ABERRANT_MITOSIS_BY_DOCETACEL_2NM_UP	81	57	All SZGR genes in this pathway
SHI_SPARC_TARGETS_UP	24	17	All SZGR genes in this pathway
MARTORIATI_MDM4_TARGETS_FETAL_LIVER_DN	514	319	All SZGR genes in this pathway
STARK_PREFRONTAL_CORTEX_22Q11_DELETION_UP	195	138	All SZGR genes in this pathway
ROZANOV_MMP14_TARGETS_DN	35	22	All SZGR genes in this pathway
LE_EGR2_TARGETS_DN	108	84	All SZGR genes in this pathway
BYSTROEM_CORRELATED_WITH_IL5_DN	64	47	All SZGR genes in this pathway
ASTON_MAJOR_DEPRESSIVE_DISORDER_DN	160	110	All SZGR genes in this pathway
FLECHNER_PBL_KIDNEY_TRANSPLANT_OK_VS_DONOR_UP	151	100	All SZGR genes in this pathway
BYSTRYKH_HEMATOPOIESIS_STEM_CELL_QTL_TRANS	882	572	All SZGR genes in this pathway
FLECHNER_BIOPSY_KIDNEY_TRANSPLANT_REJECTED_VS_OK_DN	546	351	All SZGR genes in this pathway
YAO_HOXA10_TARGETS_VIA_PROGESTERONE_UP	79	58	All SZGR genes in this pathway
CHEN_LVAD_SUPPORT_OF_FAILING_HEART_UP	103	69	All SZGR genes in this pathway
MA_PITUITARY_FETAL_VS_ADULT_UP	29	21	All SZGR genes in this pathway
BROWNE_HCMV_INFECTION_6HR_DN	160	101	All SZGR genes in this pathway
MONNIER_POSTRADIATION_TUMOR_ESCAPE_UP	393	244	All SZGR genes in this pathway
CREIGHTON_ENDOCRINE_THERAPY_RESISTANCE_4	307	185	All SZGR genes in this pathway
ZHENG_BOUND_BY_FOXP3	491	310	All SZGR genes in this pathway
ZHENG_FOXP3_TARGETS_IN_THYMUS_UP	196	137	All SZGR genes in this pathway
RIGGINS_TAMOXIFEN_RESISTANCE_DN	220	147	All SZGR genes in this pathway
MASSARWEH_TAMOXIFEN_RESISTANCE_DN	258	160	All SZGR genes in this pathway
DAIRKEE_CANCER_PRONE_RESPONSE_BPA	51	35	All SZGR genes in this pathway
RIGGI_EWING_SARCOMA_PROGENITOR_UP	430	288	All SZGR genes in this pathway
SMID_BREAST_CANCER_NORMAL_LIKE_UP	476	285	All SZGR genes in this pathway
BONOME_OVARIAN_CANCER_SURVIVAL_SUBOPTIMAL_DEBULKING	510	309	All SZGR genes in this pathway
BOQUEST_STEM_CELL_CULTURED_VS_FRESH_UP	425	298	All SZGR genes in this pathway
FIRESTEIN_PROLIFERATION	175	125	All SZGR genes in this pathway
ZHANG_TLX_TARGETS_36HR_DN	185	116	All SZGR genes in this pathway
IRITANI_MAD1_TARGETS_UP	13	8	All SZGR genes in this pathway
ROME_INSULIN_TARGETS_IN_MUSCLE_UP	442	263	All SZGR genes in this pathway
POOLA_INVASIVE_BREAST_CANCER_DN	134	83	All SZGR genes in this pathway
TCGA_GLIOBLASTOMA_MUTATED	8	8	All SZGR genes in this pathway
BOYAULT_LIVER_CANCER_SUBCLASS_G3_DN	51	32	All SZGR genes in this pathway
CHIANG_LIVER_CANCER_SUBCLASS_UNANNOTATED_UP	85	50	All SZGR genes in this pathway
KAPOSI_LIVER_CANCER_MET_DN	6	5	All SZGR genes in this pathway
YAGI_AML_WITH_T_8_21_TRANSLOCATION	368	247	All SZGR genes in this pathway
HOSHIDA_LIVER_CANCER_SUBCLASS_S3	266	180	All SZGR genes in this pathway
NAKAMURA_ADIPOGENESIS_EARLY_UP	66	44	All SZGR genes in this pathway
KARLSSON_TGFB1_TARGETS_DN	207	139	All SZGR genes in this pathway
GABRIELY_MIR21_TARGETS	289	187	All SZGR genes in this pathway
PILON_KLF1_TARGETS_DN	1972	1213	All SZGR genes in this pathway
BRUINS_UVC_RESPONSE_VIA_TP53_GROUP_A	898	516	All SZGR genes in this pathway
LEE_BMP2_TARGETS_UP	745	475	All SZGR genes in this pathway
FEVR_CTNNB1_TARGETS_DN	553	343	All SZGR genes in this pathway
PEDERSEN_METASTASIS_BY_ERBB2_ISOFORM_7	403	240	All SZGR genes in this pathway
PLASARI_TGFB1_TARGETS_10HR_DN	244	157	All SZGR genes in this pathway
PLASARI_TGFB1_SIGNALING_VIA_NFIC_1HR_DN	106	77	All SZGR genes in this pathway
ZHANG_ADIPOGENESIS_BY_BMP7	14	12	All SZGR genes in this pathway
KUMAR_PATHOGEN_LOAD_BY_MACROPHAGES	275	155	All SZGR genes in this pathway
ACEVEDO_FGFR1_TARGETS_IN_PROSTATE_CANCER_MODEL_DN	308	187	All SZGR genes in this pathway
ZWANG_TRANSIENTLY_UP_BY_1ST_EGF_PULSE_ONLY	1839	928	All SZGR genes in this pathway
ZWANG_EGF_INTERVAL_DN	214	124	All SZGR genes in this pathway

miRNA Targets ?

miRNA family	Target position			miRNA ID	miRNA seq
miRNA family	UTR start	UTR end	Match method	miRNA ID	miRNA seq
miR-103/107	3731	3737	m8	hsa-miR-103^brain	AGCAGCAUUGUACAGGGCUAUGA
miR-103/107	3731	3737	m8	hsa-miR-107^brain	AGCAGCAUUGUACAGGGCUAUCA
miR-128	481	487	m8	hsa-miR-128a	UCACAGUGAACCGGUCUCUUUU
miR-128	481	487	m8	hsa-miR-128b	UCACAGUGAACCGGUCUCUUUC
miR-129-5p	3922	3928	1A	hsa-miR-129^brain	CUUUUUGCGGUCUGGGCUUGC
				hsa-miR-129-5p	CUUUUUGCGGUCUGGGCUUGCU
				hsa-miR-129^brain	CUUUUUGCGGUCUGGGCUUGC
				hsa-miR-129-5p	CUUUUUGCGGUCUGGGCUUGCU
miR-15/16/195/424/497	3732	3739	1A,m8	hsa-miR-15a^brain	UAGCAGCACAUAAUGGUUUGUG
				hsa-miR-16^brain	UAGCAGCACGUAAAUAUUGGCG
				hsa-miR-15b^brain	UAGCAGCACAUCAUGGUUUACA
				hsa-miR-195^SZ	UAGCAGCACAGAAAUAUUGGC
				hsa-miR-424	CAGCAGCAAUUCAUGUUUUGAA
				hsa-miR-497	CAGCAGCACACUGUGGUUUGU
miR-153	800	807	1A,m8	hsa-miR-153	UUGCAUAGUCACAAAAGUGA
miR-17-5p/20/93.mr/106/519.d	1327	1333	m8	hsa-miR-17-5p	CAAAGUGCUUACAGUGCAGGUAGU
				hsa-miR-20a^brain	UAAAGUGCUUAUAGUGCAGGUAG
				hsa-miR-106a	AAAAGUGCUUACAGUGCAGGUAGC
				hsa-miR-106b^SZ	UAAAGUGCUGACAGUGCAGAU
				hsa-miR-20b^SZ	CAAAGUGCUCAUAGUGCAGGUAG
				hsa-miR-519d	CAAAGUGCCUCCCUUUAGAGUGU
miR-182	3590	3596	1A	hsa-miR-182	UUUGGCAAUGGUAGAACUCACA
miR-185	68	74	1A	hsa-miR-185^brain	UGGAGAGAAAGGCAGUUC
miR-21	1103	1109	m8	hsa-miR-21^brain	UAGCUUAUCAGACUGAUGUUGA
miR-21	1103	1109	m8	hsa-miR-590	GAGCUUAUUCAUAAAAGUGCAG
miR-218	3555	3562	1A,m8	hsa-miR-218^brain	UUGUGCUUGAUCUAACCAUGU
miR-29	327	333	m8	hsa-miR-29a^SZ	UAGCACCAUCUGAAAUCGGUU
				hsa-miR-29b^SZ	UAGCACCAUUUGAAAUCAGUGUU
				hsa-miR-29c^SZ	UAGCACCAUUUGAAAUCGGU
miR-30-3p	1639	1645	1A	hsa-miR-30a-3p	CUUUCAGUCGGAUGUUUGCAGC
miR-30-3p	1639	1645	1A	hsa-miR-30e-3p	CUUUCAGUCGGAUGUUUACAGC
miR-320	350	356	1A	hsa-miR-320	AAAAGCUGGGUUGAGAGGGCGAA
miR-33	283	289	1A	hsa-miR-33	GUGCAUUGUAGUUGCAUUG
miR-33	283	289	1A	hsa-miR-33b	GUGCAUUGCUGUUGCAUUGCA
miR-361	1100	1106	1A	hsa-miR-361^brain	UUAUCAGAAUCUCCAGGGGUAC
miR-376	996	1002	1A	hsa-miR-376a	AUCAUAGAGGAAAAUCCACGU
miR-376	996	1002	1A	hsa-miR-376b	AUCAUAGAGGAAAAUCCAUGUU
miR-448	801	807	1A	hsa-miR-448	UUGCAUAUGUAGGAUGUCCCAU
miR-450	286	292	1A	hsa-miR-450	UUUUUGCGAUGUGUUCCUAAUA
miR-486	952	959	1A,m8	hsa-miR-486	UCCUGUACUGAGCUGCCCCGAG
miR-493-5p	703	709	m8	hsa-miR-493-5p	UUGUACAUGGUAGGCUUUCAUU
miR-503	3733	3739	1A	hsa-miR-503	UAGCAGCGGGAACAGUUCUGCAG
miR-96	3590	3596	1A	hsa-miR-96^brain	UUUGGCACUAGCACAUUUUUGC

SZ: miRNAs which differentially expressed in brain cortex of schizophrenia patients comparing with control samples using microarray. Click here to see the list of SZ related miRNAs.
Brain: miRNAs which are expressed in brain based on miRNA microarray expression studies. Click here to see the list of brain related miRNAs.