Gene Page: PTK2

Summary
GeneID  5747
Symbol  PTK2
Synonyms  FADK|FAK|FAK1|pp125FAK
Description  PTK2 protein tyrosine kinase 2
See related  HGNC:9611|MIM:600758|Ensembl:ENSG00000169398|HPRD:02859|
Locus tag  -
Gene type  protein-coding
Map location  8q24-qter
 
Gene in Data Sources
Gene set name Method of gene set Evidence Info
GO_AnnotationMapping neuro-related keywords to Gene Ontology annotationsHits with neuro-related keywords: 4 
NetworkShortest path distance of core genes in the Human protein-protein interaction networkContribution to shortest path in PPI network: 1.1049 
 
General Gene Expression (microarray) ?
 
Gene Expression in Brain Regions (new)
 
Top co-expressed genes in Brain Regions (new)
GenePearson's Correlation Spearman's Correlation
Top 10 positively co-expressed genes
Top 10 negatively co-expressed genes
Gene Ontology
Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0000166nucleotide bindingIEA-
GO:0004871signal transducer activityIEA-
GO:0005515protein bindingIPI8649368 |10822899 |14688263 
GO:0005524ATP bindingIEA-
GO:0004713protein tyrosine kinase activityIEA-
GO:0004715non-membrane spanning protein tyrosine kinase activityIEA-
GO:0016740transferase activityIEA-
GO:0042169SH2 domain bindingIPI15077193 
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0001764neuron migrationIEAneuron (GO term level: 8)-
GO:0051964negative regulation of synaptogenesisIEASynap (GO term level: 10)-
GO:0021955central nervous system neuron axonogenesisIEAneuron, axon (GO term level: 13)-
GO:0050771negative regulation of axonogenesisIEAaxon, neurogenesis (GO term level: 14)-
GO:0000226microtubule cytoskeleton organizationIEA-
GO:0001570vasculogenesisIEA-
GO:0001568blood vessel developmentIEA-
GO:0001525angiogenesisIEA-
GO:0007172signal complex assemblyIEA-
GO:0006468protein amino acid phosphorylationIEA-
GO:0007229integrin-mediated signaling pathwayTAS9636140 
GO:0040023establishment of nucleus localizationIEA-
GO:0030198extracellular matrix organizationIEA-
GO:0043542endothelial cell migrationIEA-
GO:0046621negative regulation of organ growthIEA-
GO:0046777protein amino acid autophosphorylationIEA-
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0005829cytosolEXP9325343 
GO:0005856cytoskeletonIEA-
GO:0005856cytoskeletonTAS10801330 
GO:0005737cytoplasmIDA18029348 
GO:0030027lamellipodiumIEA-
GO:0005925focal adhesionIEA-
GO:0005886plasma membraneIEA-
GO:0016324apical plasma membraneIEA-
GO:0030054cell junctionIDA18029348 
GO:0030054cell junctionIEA-
 
Protein-protein InteractionsShown by network
InteractorsAliases BOfficial full name BExperimentalSourcePubMed ID
AMPHAMPH1amphiphysinAffinity Capture-WesternBioGRID12558988 
APCBTPS2 | DP2 | DP2.5 | DP3 | GSadenomatous polyposis coli-HPRD7744883 
ARHGAP26FLJ42530 | GRAF | KIAA0621 | OPHN1L | OPHN1L1Rho GTPase activating protein 26-HPRD,BioGRID8649427 
ASAP1AMAP1 | CENTB4 | DDEF1 | KIAA1249 | PAG2 | PAP | ZG14PArfGAP with SH3 domain, ankyrin repeat and PH domain 1-HPRD12058076 
ATG12APG12 | APG12L | FBR93 | HAPG12ATG12 autophagy related 12 homolog (S. cerevisiae)Two-hybridBioGRID16189514 
BCAR1CAS | CAS1 | CASS1 | CRKAS | P130Casbreast cancer anti-estrogen resistance 1-HPRD11514617 
Affinity Capture-Western
Reconstituted Complex		BioGRID8649427 |8810278 
|11577104 |12135674 
|12615911 
-HPRD7479864 |11514617 
CAS interacts with FAK. This interaction was modeled on a demonstrated interaction between human CAS and mouse FAK.BIND9148935 
BIN1AMPH2 | AMPHL | DKFZp547F068 | MGC10367 | SH3P9bridging integrator 1-HPRD,BioGRID12558988 
BMXETK | PSCTK2 | PSCTK3BMX non-receptor tyrosine kinase-HPRD,BioGRID11331870 
CCR5CC-CKR-5 | CCCKR5 | CD195 | CKR-5 | CKR5 | CMKBR5chemokine (C-C motif) receptor 5-HPRD,BioGRID10384144 
CD4CD4mutCD4 molecule-HPRD10384144 
CD47IAP | MER6 | OA3CD47 molecule-HPRD9169439 
CIB1CIB | KIP | KIP1 | SIP2-28calcium and integrin binding 1 (calmyrin)-HPRD,BioGRID12881299 
CRKCRKIIv-crk sarcoma virus CT10 oncogene homolog (avian)Affinity Capture-Western
Reconstituted Complex		BioGRID10085298 |12615911 
CRKL-v-crk sarcoma virus CT10 oncogene homolog (avian)-likeTwo-hybridBioGRID15494733 
CSKMGC117393c-src tyrosine kinase-HPRD,BioGRID7529872 
CSPG4HMW-MAA | MCSP | MCSPG | MEL-CSPG | MSK16 | NG2chondroitin sulfate proteoglycan 4-HPRD10587647 
CXCR4CD184 | D2S201E | FB22 | HM89 | HSY3RR | LAP3 | LCR1 | LESTR | NPY3R | NPYR | NPYRL | NPYY3R | WHIMchemokine (C-X-C motif) receptor 4Affinity Capture-WesternBioGRID11668182 
DCCCRC18 | CRCR1deleted in colorectal carcinomaAffinity Capture-Western
Two-hybrid		BioGRID15494733 
DCC interacts with FAK.BIND15494732 
FAK interacts with DCC.BIND15494733 
DNM2CMTDI1 | CMTDIB | DI-CMTB | DYN2 | DYNIIdynamin 2PTK2 (FAK) interacts with DNM2 (DYN2).BIND15895076 
DOCK1DOCK180 | ced5dedicator of cytokinesis 1Affinity Capture-WesternBioGRID12615911 
EFSCAS3 | CASS3 | EFS1 | EFS2 | HEFS | SINembryonal Fyn-associated substrate-HPRD9750131 
EGFRERBB | ERBB1 | HER1 | PIG61 | mENAepidermal growth factor receptor (erythroblastic leukemia viral (v-erb-b) oncogene homolog, avian)-HPRD,BioGRID10806474 
EPHA2ECKEPH receptor A2-HPRD,BioGRID10655584 
ERBB2CD340 | HER-2 | HER-2/neu | HER2 | NEU | NGL | TKR1v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian)-HPRD11807823 
ERBB3ErbB-3 | HER3 | LCCS2 | MDA-BF-1 | MGC88033 | c-erbB-3 | c-erbB3 | erbB3-S | p180-ErbB3 | p45-sErbB3 | p85-sErbB3v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian)-HPRD11807823 
EZRCVIL | CVL | DKFZp762H157 | FLJ26216 | MGC1584 | VIL2ezrin-HPRD,BioGRID11468295 
FGRFLJ43153 | MGC75096 | SRC2 | c-fgr | c-src2 | p55c-fgr | p58c-fgrGardner-Rasheed feline sarcoma viral (v-fgr) oncogene homolog-HPRD,BioGRID12387730 
FYNMGC45350 | SLK | SYNFYN oncogene related to SRC, FGR, YES-HPRD,BioGRID11278857 
GIT1-G protein-coupled receptor kinase interacting ArfGAP 1-HPRD,BioGRID10938112 
GRB2ASH | EGFRBP-GRB2 | Grb3-3 | MST084 | MSTP084growth factor receptor-bound protein 2Tyrosine-phosphorylated FAK interacts with Grb2.BIND7597091 
-HPRD7997267 
Affinity Capture-Western
Reconstituted Complex		BioGRID8649427 |10085298 
|10806474 |12005431 
|12558988 
Grb2 interacts with FAK. This interaction was modeled on a demonstrated interaction between human Grb2 and mouse FAK.BIND9148935 
GRB7-growth factor receptor-bound protein 7-HPRD,BioGRID10446223 
GSK3B-glycogen synthase kinase 3 beta-HPRD,BioGRID11809746 
GSNDKFZp313L0718gelsolin (amyloidosis, Finnish type)Affinity Capture-WesternBioGRID11577104 
IGF1RCD221 | IGFIR | JTK13 | MGC142170 | MGC142172 | MGC18216insulin-like growth factor 1 receptorAffinity Capture-WesternBioGRID10082579 
IRS1HIRS-1insulin receptor substrate 1-HPRD,BioGRID9822703 
ITGA4CD49D | IA4 | MGC90518integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor)Affinity Capture-WesternBioGRID11919182 
ITGAVCD51 | DKFZp686A08142 | MSK8 | VNRAintegrin, alpha V (vitronectin receptor, alpha polypeptide, antigen CD51)-HPRD11927607 
ITGB1CD29 | FNRB | GPIIA | MDF2 | MSK12 | VLA-BETA | VLABintegrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)-HPRD8649427 
ITGB2CD18 | LAD | LCAMB | LFA-1 | MAC-1 | MF17 | MFI7integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)-HPRD8649427 
ITGB3CD61 | GP3A | GPIIIaintegrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)FAK interacts with integrin beta 3.BIND11927607 
Affinity Capture-Western
Reconstituted Complex		BioGRID9169439 |11927607 
-HPRD8649427 
ITGB5FLJ26658integrin, beta 5Affinity Capture-Western
Reconstituted Complex		BioGRID11927607 
JAK2JTK10Janus kinase 2 (a protein tyrosine kinase)-HPRD,BioGRID9553131 |10925297 
KCNMA1BKTM | DKFZp686K1437 | KCa1.1 | MGC71881 | MaxiK | SAKCA | SLO | SLO-ALPHA | SLO1 | mSLO1potassium large conductance calcium-activated channel, subfamily M, alpha member 1-HPRD14584897 
LYNFLJ26625 | JTK8v-yes-1 Yamaguchi sarcoma viral related oncogene homologAffinity Capture-WesternBioGRID9169439 
-HPRD11389892 
MAPK8IP3DKFZp762N1113 | FLJ00027 | JIP3 | JSAP1 | KIAA1066 | SYD2mitogen-activated protein kinase 8 interacting protein 3Affinity Capture-WesternBioGRID12226752 
MICAL1DKFZp434B1517 | FLJ11937 | FLJ21739 | MICAL | MICAL-1 | NICALmicrotubule associated monoxygenase, calponin and LIM domain containing 1-HPRD10808124 
NCK1MGC12668 | NCK | NCKalphaNCK adaptor protein 1Affinity Capture-Western
Reconstituted Complex		BioGRID8879209 |11950595 
NCK2GRB4 | NCKbetaNCK adaptor protein 2-HPRD,BioGRID11950595 
NEDD9CAS-L | CAS2 | CASL | CASS2 | HEF1 | dJ49G10.2 | dJ761I2.1neural precursor cell expressed, developmentally down-regulated 9-HPRD,BioGRID8668148 |8879209 
|10455189 
NEO1DKFZp547A066 | DKFZp547B146 | HsT17534 | NGNneogenin homolog 1 (chicken)FAK interacts with Neogenin.BIND15494733 
PCSK1BMIQ12 | NEC1 | PC1 | PC3 | SPC3proprotein convertase subtilisin/kexin type 1Affinity Capture-WesternBioGRID11113628 
PDGFRBCD140B | JTK12 | PDGF-R-beta | PDGFR | PDGFR1platelet-derived growth factor receptor, beta polypeptide-HPRD10806474 
PIAS1DDXBP1 | GBP | GU/RH-II | MGC141878 | MGC141879 | ZMIZ3protein inhibitor of activated STAT, 1-HPRD14500712 
PIK3R1GRB1 | p85 | p85-ALPHAphosphoinositide-3-kinase, regulatory subunit 1 (alpha)-HPRD,BioGRID7537275 |8649427 
|10806474 
PKD1PBPpolycystic kidney disease 1 (autosomal dominant)-HPRD11113628 
polycystin-1 interacts with FAK.BIND11113628 
PLCG1PLC-II | PLC1 | PLC148 | PLCgamma1phospholipase C, gamma 1-HPRD,BioGRID8660853|10430888 
PPP1CBMGC3672 | PP-1B | PPP1CDprotein phosphatase 1, catalytic subunit, beta isoform-HPRD,BioGRID11513739 
PTEN10q23del | BZS | MGC11227 | MHAM | MMAC1 | PTEN1 | TEP1phosphatase and tensin homolog-HPRD,BioGRID10400703 
PTK2FADK | FAK | FAK1 | pp125FAKPTK2 protein tyrosine kinase 2FAK autophosphorylates.BIND11359909 
-HPRD,BioGRID12005431 
PTPN11BPTP3 | CFC | MGC14433 | NS1 | PTP-1D | PTP2C | SH-PTP2 | SH-PTP3 | SHP2protein tyrosine phosphatase, non-receptor type 11-HPRD,BioGRID7589239 |8986614 
|10082579 |10655584 
PTPN12PTP-PEST | PTPG1protein tyrosine phosphatase, non-receptor type 12-HPRD9497381 
PTPRHFLJ39938 | MGC133058 | MGC133059 | SAP-1protein tyrosine phosphatase, receptor type, H-HPRD11278335 
PXNFLJ16691paxillinFAK interacts with paxillin.BIND11113628 
-HPRD,BioGRID8922390 
RB1CC1CC1 | DRAGOU14 | FIP200RB1-inducible coiled-coil 1-HPRD,BioGRID10769033 
RIPK1FLJ39204 | RIP | RIP1receptor (TNFRSF)-interacting serine-threonine kinase 1FAK interacts with RIP.BIND15121855 
SELECD62E | ELAM | ELAM1 | ESEL | LECAM2selectin E-HPRD,BioGRID8609175 
SHC1FLJ26504 | SHC | SHCASHC (Src homology 2 domain containing) transforming protein 1-HPRD,BioGRID11980671 
Shc interacts with FAK. This interaction was modeled on a demonstrated interaction between human Shc and mouse FAK.BIND9148935 
SOCS2CIS2 | Cish2 | SOCS-2 | SSI-2 | SSI2 | STATI2suppressor of cytokine signaling 2Two-hybridBioGRID16189514 
SORBS1CAP | DKFZp451C066 | DKFZp586P1422 | FLAF2 | FLJ12406 | KIAA1296 | R85FL | SH3D5 | SH3P12 | SORB1sorbin and SH3 domain containing 1-HPRD9461600 
SRCASV | SRC1 | c-SRC | p60-Srcv-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian)c-Src interacts with FAK. This interaction was modeled on a demonstrated interaction between human c-Src and mouse FAK.BIND9148935 
Affinity Capture-Western
Reconstituted Complex		BioGRID10085298 |11980671 
|12387730 |12558988 
|12615911 
-HPRD7529876 |8054685 
|10931187 
-HPRD7529876 |8054685 
Src interacts with tyrosine autophosphorylated FAK. This interaction was modeled on a demonstrated interaction between human Src and avian FAK.BIND7515480 
STAT1DKFZp686B04100 | ISGF-3 | STAT91signal transducer and activator of transcription 1, 91kDa-HPRD,BioGRID11278462 
STAT3APRF | FLJ20882 | HIES | MGC16063signal transducer and activator of transcription 3 (acute-phase response factor)Affinity Capture-WesternBioGRID10925297 
SYKDKFZp313N1010 | FLJ25043 | FLJ37489spleen tyrosine kinase-HPRD,BioGRID9169439 |9342235 
TGFB1I1ARA55 | HIC-5 | HIC5 | TSC-5transforming growth factor beta 1 induced transcript 1-HPRD9422762 |9756887 
Affinity Capture-Western
Reconstituted Complex		BioGRID9422762 |9858471 
|11463817 
TLN1ILWEQ | KIAA1027 | TLNtalin 1-HPRD,BioGRID7622520 
TRIP6MGC10556 | MGC10558 | MGC29959 | MGC3837 | MGC4423 | OIP1 | ZRP-1thyroid hormone receptor interactor 6-HPRD,BioGRID14688263 
TSC1KIAA0243 | LAM | MGC86987 | TSCtuberous sclerosis 1Affinity Capture-WesternBioGRID17043358 
TSC2FLJ43106 | LAM | TSC4tuberous sclerosis 2Affinity Capture-Western
Reconstituted Complex		BioGRID17043358 
YES1HsT441 | P61-YES | Yes | c-yesv-yes-1 Yamaguchi sarcoma viral oncogene homolog 1Affinity Capture-WesternBioGRID12558988 
 
Pathway annotation
Pathway namePathway size# SZGR genes in pathwayInfo
KEGG_ERBB_SIGNALING_PATHWAY 8771All SZGR genes in this pathway
KEGG_CHEMOKINE_SIGNALING_PATHWAY 190128All SZGR genes in this pathway
KEGG_AXON_GUIDANCE 129103All SZGR genes in this pathway
KEGG_VEGF_SIGNALING_PATHWAY 7653All SZGR genes in this pathway
KEGG_FOCAL_ADHESION 201138All SZGR genes in this pathway
KEGG_LEUKOCYTE_TRANSENDOTHELIAL_MIGRATION 11878All SZGR genes in this pathway
KEGG_REGULATION_OF_ACTIN_CYTOSKELETON 216144All SZGR genes in this pathway
KEGG_PATHWAYS_IN_CANCER 328259All SZGR genes in this pathway
KEGG_SMALL_CELL_LUNG_CANCER 8467All SZGR genes in this pathway
BIOCARTA_AGR_PATHWAY 3631All SZGR genes in this pathway
BIOCARTA_AT1R_PATHWAY 3628All SZGR genes in this pathway
BIOCARTA_CHEMICAL_PATHWAY 2215All SZGR genes in this pathway
BIOCARTA_SPPA_PATHWAY 2218All SZGR genes in this pathway
BIOCARTA_CCR3_PATHWAY 2321All SZGR genes in this pathway
BIOCARTA_CELL2CELL_PATHWAY 1411All SZGR genes in this pathway
BIOCARTA_CXCR4_PATHWAY 2422All SZGR genes in this pathway
BIOCARTA_ECM_PATHWAY 2417All SZGR genes in this pathway
BIOCARTA_HIVNEF_PATHWAY 5843All SZGR genes in this pathway
BIOCARTA_INTEGRIN_PATHWAY 3829All SZGR genes in this pathway
BIOCARTA_MCALPAIN_PATHWAY 2516All SZGR genes in this pathway
BIOCARTA_EDG1_PATHWAY 2724All SZGR genes in this pathway
BIOCARTA_PTEN_PATHWAY 1814All SZGR genes in this pathway
BIOCARTA_ACH_PATHWAY 1613All SZGR genes in this pathway
BIOCARTA_MET_PATHWAY 3730All SZGR genes in this pathway
BIOCARTA_TFF_PATHWAY 2115All SZGR genes in this pathway
BIOCARTA_UCALPAIN_PATHWAY 1811All SZGR genes in this pathway
BIOCARTA_VEGF_PATHWAY 2918All SZGR genes in this pathway
SIG_PIP3_SIGNALING_IN_CARDIAC_MYOCTES 6754All SZGR genes in this pathway
ST_GA12_PATHWAY 2316All SZGR genes in this pathway
ST_INTEGRIN_SIGNALING_PATHWAY 8262All SZGR genes in this pathway
ST_GA13_PATHWAY 3732All SZGR genes in this pathway
PID_FCER1_PATHWAY 6243All SZGR genes in this pathway
PID_LYSOPHOSPHOLIPID_PATHWAY 6653All SZGR genes in this pathway
PID_MET_PATHWAY 8060All SZGR genes in this pathway
PID_EPHB_FWD_PATHWAY 4038All SZGR genes in this pathway
PID_NECTIN_PATHWAY 3020All SZGR genes in this pathway
PID_RET_PATHWAY 3929All SZGR genes in this pathway
PID_ANGIOPOIETIN_RECEPTOR_PATHWAY 5041All SZGR genes in this pathway
PID_NETRIN_PATHWAY 3227All SZGR genes in this pathway
PID_CXCR4_PATHWAY 10278All SZGR genes in this pathway
PID_IGF1_PATHWAY 3023All SZGR genes in this pathway
PID_ERBB1_RECEPTOR_PROXIMAL_PATHWAY 3529All SZGR genes in this pathway
PID_AVB3_INTEGRIN_PATHWAY 7553All SZGR genes in this pathway
PID_SYNDECAN_4_PATHWAY 3225All SZGR genes in this pathway
PID_AR_NONGENOMIC_PATHWAY 3127All SZGR genes in this pathway
PID_ERBB1_INTERNALIZATION_PATHWAY 4135All SZGR genes in this pathway
PID_CASPASE_PATHWAY 5239All SZGR genes in this pathway
PID_VEGFR1_2_PATHWAY 6957All SZGR genes in this pathway
PID_EPHA2_FWD_PATHWAY 1916All SZGR genes in this pathway
PID_INTEGRIN_A4B1_PATHWAY 3324All SZGR genes in this pathway
PID_FAK_PATHWAY 5945All SZGR genes in this pathway
REACTOME_APOPTOTIC_CLEAVAGE_OF_CELLULAR_PROTEINS 4026All SZGR genes in this pathway
REACTOME_DEVELOPMENTAL_BIOLOGY 396292All SZGR genes in this pathway
REACTOME_CELL_CELL_COMMUNICATION 12077All SZGR genes in this pathway
REACTOME_INTEGRIN_CELL_SURFACE_INTERACTIONS 7948All SZGR genes in this pathway
REACTOME_P130CAS_LINKAGE_TO_MAPK_SIGNALING_FOR_INTEGRINS 1511All SZGR genes in this pathway
REACTOME_GRB2_SOS_PROVIDES_LINKAGE_TO_MAPK_SIGNALING_FOR_INTERGRINS_ 1510All SZGR genes in this pathway
REACTOME_INTEGRIN_ALPHAIIB_BETA3_SIGNALING 2717All SZGR genes in this pathway
REACTOME_AXON_GUIDANCE 251188All SZGR genes in this pathway
REACTOME_NCAM_SIGNALING_FOR_NEURITE_OUT_GROWTH 6449All SZGR genes in this pathway
REACTOME_NETRIN1_SIGNALING 4130All SZGR genes in this pathway
REACTOME_DCC_MEDIATED_ATTRACTIVE_SIGNALING 1311All SZGR genes in this pathway
REACTOME_SIGNAL_REGULATORY_PROTEIN_SIRP_FAMILY_INTERACTIONS 1210All SZGR genes in this pathway
REACTOME_PLATELET_AGGREGATION_PLUG_FORMATION 3623All SZGR genes in this pathway
REACTOME_APOPTOSIS 14894All SZGR genes in this pathway
REACTOME_HEMOSTASIS 466331All SZGR genes in this pathway
REACTOME_PLATELET_ACTIVATION_SIGNALING_AND_AGGREGATION 208138All SZGR genes in this pathway
REACTOME_APOPTOTIC_EXECUTION_PHASE 5437All SZGR genes in this pathway
ONKEN_UVEAL_MELANOMA_UP 783507All SZGR genes in this pathway
THUM_SYSTOLIC_HEART_FAILURE_UP 423283All SZGR genes in this pathway
CASORELLI_ACUTE_PROMYELOCYTIC_LEUKEMIA_DN 663425All SZGR genes in this pathway
HUTTMANN_B_CLL_POOR_SURVIVAL_DN 6039All SZGR genes in this pathway
DEURIG_T_CELL_PROLYMPHOCYTIC_LEUKEMIA_UP 368234All SZGR genes in this pathway
DITTMER_PTHLH_TARGETS_DN 7351All SZGR genes in this pathway
TIEN_INTESTINE_PROBIOTICS_2HR_UP 2719All SZGR genes in this pathway
CHIN_BREAST_CANCER_COPY_NUMBER_UP 2718All SZGR genes in this pathway
LINDGREN_BLADDER_CANCER_CLUSTER_2B 392251All SZGR genes in this pathway
PATIL_LIVER_CANCER 747453All SZGR genes in this pathway
DACOSTA_UV_RESPONSE_VIA_ERCC3_DN 855609All SZGR genes in this pathway
DACOSTA_UV_RESPONSE_VIA_ERCC3_COMMON_DN 483336All SZGR genes in this pathway
NUYTTEN_EZH2_TARGETS_DN 1024594All SZGR genes in this pathway
NIKOLSKY_BREAST_CANCER_8Q23_Q24_AMPLICON 15787All SZGR genes in this pathway
HADDAD_T_LYMPHOCYTE_AND_NK_PROGENITOR_UP 7856All SZGR genes in this pathway
GENTILE_UV_RESPONSE_CLUSTER_D6 3725All SZGR genes in this pathway
GENTILE_UV_HIGH_DOSE_DN 312203All SZGR genes in this pathway
CHIBA_RESPONSE_TO_TSA_DN 2314All SZGR genes in this pathway
DAZARD_RESPONSE_TO_UV_NHEK_DN 318220All SZGR genes in this pathway
DAZARD_UV_RESPONSE_CLUSTER_G6 153112All SZGR genes in this pathway
YIH_RESPONSE_TO_ARSENITE_C1 2414All SZGR genes in this pathway
MARSON_BOUND_BY_FOXP3_UNSTIMULATED 1229713All SZGR genes in this pathway
HELLER_HDAC_TARGETS_SILENCED_BY_METHYLATION_UP 461298All SZGR genes in this pathway
LEE_METASTASIS_AND_ALTERNATIVE_SPLICING_DN 4531All SZGR genes in this pathway
RIZKI_TUMOR_INVASIVENESS_3D_UP 210124All SZGR genes in this pathway
FUJII_YBX1_TARGETS_DN 202132All SZGR genes in this pathway
BOCHKIS_FOXA2_TARGETS 425261All SZGR genes in this pathway
GRADE_COLON_CANCER_UP 871505All SZGR genes in this pathway
LU_TUMOR_ANGIOGENESIS_UP 2522All SZGR genes in this pathway
BOYLAN_MULTIPLE_MYELOMA_C_D_UP 13995All SZGR genes in this pathway
GU_PDEF_TARGETS_UP 7149All SZGR genes in this pathway
YOSHIMURA_MAPK8_TARGETS_UP 1305895All SZGR genes in this pathway
AGUIRRE_PANCREATIC_CANCER_COPY_NUMBER_UP 298174All SZGR genes in this pathway
WENDT_COHESIN_TARGETS_UP 3319All SZGR genes in this pathway
JISON_SICKLE_CELL_DISEASE_UP 181106All SZGR genes in this pathway
FONTAINE_FOLLICULAR_THYROID_ADENOMA_UP 7543All SZGR genes in this pathway
FONTAINE_THYROID_TUMOR_UNCERTAIN_MALIGNANCY_UP 3623All SZGR genes in this pathway
CAIRO_HEPATOBLASTOMA_CLASSES_UP 605377All SZGR genes in this pathway
YAO_TEMPORAL_RESPONSE_TO_PROGESTERONE_CLUSTER_7 7646All SZGR genes in this pathway
KARLSSON_TGFB1_TARGETS_UP 12778All SZGR genes in this pathway
CHYLA_CBFA2T3_TARGETS_DN 242146All SZGR genes in this pathway
JOHNSTONE_PARVB_TARGETS_2_DN 336211All SZGR genes in this pathway
JOHNSTONE_PARVB_TARGETS_3_DN 918550All SZGR genes in this pathway
BRUINS_UVC_RESPONSE_VIA_TP53_GROUP_D 280158All SZGR genes in this pathway
BRUINS_UVC_RESPONSE_MIDDLE 9856All SZGR genes in this pathway
KOINUMA_TARGETS_OF_SMAD2_OR_SMAD3 824528All SZGR genes in this pathway
miRNA Targets ?
miRNA familyTarget positionmiRNA IDmiRNA seq
UTR startUTR endMatch method
miR-135820826m8hsa-miR-135aUAUGGCUUUUUAUUCCUAUGUGA
hsa-miR-135bUAUGGCUUUUCAUUCCUAUGUG
miR-13856631A,m8hsa-miR-138brainAGCUGGUGUUGUGAAUC
miR-1998448501Ahsa-miR-199aCCCAGUGUUCAGACUACCUGUUC
hsa-miR-199bCCCAGUGUUUAGACUAUCUGUUC
miR-25/32/92/363/3674955011Ahsa-miR-25brainCAUUGCACUUGUCUCGGUCUGA
hsa-miR-32UAUUGCACAUUACUAAGUUGC
hsa-miR-92UAUUGCACUUGUCCCGGCCUG
hsa-miR-367AAUUGCACUUUAGCAAUGGUGA
hsa-miR-92bSZUAUUGCACUCGUCCCGGCCUC
miR-378100310091Ahsa-miR-378CUCCUGACUCCAGGUCCUGUGU
miR-4107958011Ahsa-miR-410AAUAUAACACAGAUGGCCUGU
miR-7875881m8hsa-miR-7SZUGGAAGACUAGUGAUUUUGUUG
  • SZ: miRNAs which differentially expressed in brain cortex of schizophrenia patients comparing with control samples using microarray. Click here to see the list of SZ related miRNAs.
  • Brain: miRNAs which are expressed in brain based on miRNA microarray expression studies. Click here to see the list of brain related miRNAs.


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