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Association Linkage Expression Literature GO_Annotation Gene Network miRNA Targets

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Association Linkage Expression Literature GO_Annotation Gene Network miRNA Targets Datasets Gene Ranking

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Gene Page: TRAF1

Summary

GeneID

7185

Symbol

TRAF1

Synonyms

EBI6|MGC:10353

Description

TNF receptor-associated factor 1

Locus tag

Gene type

protein-coding

Map location

9q33-q34

Gene in Data Sources

Gene set name

Method of gene set

Evidence

Info

Literature

High-throughput literature-search

Co-occurance with Schizophrenia keywords: [schizophrenias, schizophrenic, schizophrenia]

Click to show detail

General Gene Expression (microarray) ?

Gene Expression in Brain Regions (new)

Top co-expressed genes in Brain Regions (new)

Gene

Pearson's Correlation

Spearman's Correlation

Top 10 positively co-expressed genes

Top 10 negatively co-expressed genes

Gene Ontology

Molecular function

GO term

Evidence

Neuro keywords

PubMed ID

GO:0005515

protein binding

IPI

9162022 |10809768

GO:0008270

zinc ion binding

IEA

Biological process

GO term

Evidence

Neuro keywords

PubMed ID

GO:0006461

protein complex assembly

TAS

8069916

GO:0007165

signal transduction

IEA

GO:0042981

regulation of apoptosis

IEA

Cellular component

GO term

Evidence

Neuro keywords

PubMed ID

GO:0005737

cytoplasm

TAS

8069916

Protein-protein Interactions

Shown by network

Interactors	Aliases B	Official full name B	Experimental	Source	PubMed ID
APIP	APIP2 \| CGI-29 \| MMRP19 \| dJ179L10.2	APAF1 interacting protein	-	HPRD	14743216
BIRC2	API1 \| HIAP2 \| Hiap-2 \| MIHB \| RNF48 \| cIAP1	baculoviral IAP repeat-containing 2	c-IAP1 interacts with TRAF1.	BIND	11907583
BIRC2	API1 \| HIAP2 \| Hiap-2 \| MIHB \| RNF48 \| cIAP1	baculoviral IAP repeat-containing 2	-	HPRD,BioGRID	9384571 \|11907583
BIRC3	AIP1 \| API2 \| CIAP2 \| HAIP1 \| HIAP1 \| MALT2 \| MIHC \| RNF49	baculoviral IAP repeat-containing 3	-	HPRD,BioGRID	11907583
BIRC3	AIP1 \| API2 \| CIAP2 \| HAIP1 \| HIAP1 \| MALT2 \| MIHC \| RNF49	baculoviral IAP repeat-containing 3	c-IAP2 interacts with TRAF1.	BIND	11907583
CASP10	ALPS2 \| FLICE2 \| MCH4	caspase 10, apoptosis-related cysteine peptidase	Biochemical Activity	BioGRID	11098060
CASP3	CPP32 \| CPP32B \| SCA-1	caspase 3, apoptosis-related cysteine peptidase	-	HPRD	11098060
CASP6	MCH2	caspase 6, apoptosis-related cysteine peptidase	Biochemical Activity	BioGRID	11098060
CASP8	ALPS2B \| CAP4 \| FLICE \| FLJ17672 \| MACH \| MCH5 \| MGC78473	caspase 8, apoptosis-related cysteine peptidase	Affinity Capture-Western Biochemical Activity	BioGRID	11098060 \|12887920
CD27	MGC20393 \| S152 \| T14 \| TNFRSF7 \| Tp55	CD27 molecule	Affinity Capture-Western	BioGRID	9794406
CD40	Bp50 \| CDW40 \| MGC9013 \| TNFRSF5 \| p50	CD40 molecule, TNF receptor superfamily member 5	-	HPRD	7527023 \|10411888
CFLAR	CASH \| CASP8AP1 \| CLARP \| Casper \| FLAME \| FLAME-1 \| FLAME1 \| FLIP \| I-FLICE \| MRIT \| c-FLIP \| c-FLIPL \| c-FLIPR \| c-FLIPS	CASP8 and FADD-like apoptosis regulator	-	HPRD,BioGRID	9208847
HIVEP3	FLJ16752 \| KBP-1 \| KBP1 \| KIAA1555 \| KRC \| SHN3 \| Schnurri-3 \| ZAS3 \| ZNF40C	human immunodeficiency virus type I enhancer binding protein 3	-	HPRD,BioGRID	11804591
HSPA8	HSC54 \| HSC70 \| HSC71 \| HSP71 \| HSP73 \| HSPA10 \| LAP1 \| MGC131511 \| MGC29929 \| NIP71	heat shock 70kDa protein 8	-	HPRD	14743216
LTBR	CD18 \| D12S370 \| LT-BETA-R \| TNF-R-III \| TNFCR \| TNFR-RP \| TNFR2-RP \| TNFRSF3	lymphotoxin beta receptor (TNFR superfamily, member 3)	Reconstituted Complex	BioGRID	9162022
MAP3K14	FTDCR1B \| HS \| HSNIK \| NIK	mitogen-activated protein kinase kinase kinase 14	-	HPRD,BioGRID	11278268
MAP3K14	FTDCR1B \| HS \| HSNIK \| NIK	mitogen-activated protein kinase kinase kinase 14	NIK interacts with TRAF1. This interaction was modeled on a demonstrated interaction between human NIK and TRAF1 from an unspecified species.	BIND	9275204
MAP3K5	ASK1 \| MAPKKK5 \| MEKK5	mitogen-activated protein kinase kinase kinase 5	Affinity Capture-Western	BioGRID	9774977
MAP6	FLJ41346 \| KIAA1878 \| MTAP6 \| N-STOP \| STOP	microtubule-associated protein 6	in vitro	BioGRID	11279055
NGFR	CD271 \| Gp80-LNGFR \| TNFRSF16 \| p75(NTR) \| p75NTR	nerve growth factor receptor (TNFR superfamily, member 16)	Affinity Capture-Western	BioGRID	10514511
RIPK1	FLJ39204 \| RIP \| RIP1	receptor (TNFRSF)-interacting serine-threonine kinase 1	-	HPRD,BioGRID	8612133
RIPK2	CARD3 \| CARDIAK \| CCK \| GIG30 \| RICK \| RIP2	receptor-interacting serine-threonine kinase 2	-	HPRD,BioGRID	9705938
RPS3	FLJ26283 \| FLJ27450 \| MGC87870	ribosomal protein S3	-	HPRD	14743216
SPOP	TEF2	speckle-type POZ protein	-	HPRD	11279055
SRC	ASV \| SRC1 \| c-SRC \| p60-Src	v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian)	Affinity Capture-Western	BioGRID	10635328
TANK	I-TRAF \| TRAF2	TRAF family member-associated NFKB activator	-	HPRD,BioGRID	8710854
TNFAIP3	A20 \| MGC104522 \| MGC138687 \| MGC138688 \| OTUD7C \| TNFA1P2	tumor necrosis factor, alpha-induced protein 3	-	HPRD,BioGRID	8692885
TNFRSF11A	CD265 \| FEO \| LOH18CR1 \| ODFR \| OFE \| OPTB7 \| OSTS \| PDB2 \| RANK \| TRANCER	tumor necrosis factor receptor superfamily, member 11a, NFKB activator	-	HPRD,BioGRID	9774460 \|9852070 \|10025951
TNFRSF12A	CD266 \| FN14 \| TWEAKR	tumor necrosis factor receptor superfamily, member 12A	-	HPRD,BioGRID	11728344
TNFRSF14	ATAR \| HVEA \| HVEM \| LIGHTR \| TR2	tumor necrosis factor receptor superfamily, member 14 (herpesvirus entry mediator)	-	HPRD,BioGRID	9162022
TNFRSF17	BCM \| BCMA \| CD269	tumor necrosis factor receptor superfamily, member 17	-	HPRD,BioGRID	10903733
TNFRSF18	AITR \| GITR \| GITR-D	tumor necrosis factor receptor superfamily, member 18	-	HPRD,BioGRID	10037686
TNFRSF19	TAJ \| TAJ-alpha \| TRADE \| TROY	tumor necrosis factor receptor superfamily, member 19	-	HPRD,BioGRID	10809768
TNFRSF1A	CD120a \| FPF \| MGC19588 \| TBP1 \| TNF-R \| TNF-R-I \| TNF-R55 \| TNFAR \| TNFR1 \| TNFR55 \| TNFR60 \| p55 \| p55-R \| p60	tumor necrosis factor receptor superfamily, member 1A	-	HPRD,BioGRID	8565075
TNFRSF1B	CD120b \| TBPII \| TNF-R-II \| TNF-R75 \| TNFBR \| TNFR1B \| TNFR2 \| TNFR80 \| p75 \| p75TNFR	tumor necrosis factor receptor superfamily, member 1B	-	HPRD	8069916
TNFRSF1B		tumor necrosis factor receptor superfamily, member 1B	Reconstituted Complex	BioGRID	9162022
TNFRSF8	CD30 \| D1S166E \| KI-1	tumor necrosis factor receptor superfamily, member 8	-	HPRD,BioGRID	8627180 \|8943059 \|9168896\|8943059
			-	HPRD	8943059
			TRAF1 interacts with CD30.	BIND	8662842
TNFRSF9	4-1BB \| CD137 \| CDw137 \| ILA \| MGC2172	tumor necrosis factor receptor superfamily, member 9	-	HPRD,BioGRID	9464265
TNFSF9	4-1BB-L \| CD137L	tumor necrosis factor (ligand) superfamily, member 9	-	HPRD,BioGRID	9418902 \|9607925
TRADD	Hs.89862 \| MGC11078	TNFRSF1A-associated via death domain	-	HPRD,BioGRID	8565075
TRAF2	MGC:45012 \| TRAP \| TRAP3	TNF receptor-associated factor 2	TRAF2 interacts with TRAF1. This interaction was modeled on a demonstrated interaction between human TRAF2 and mouse TRAF1.	BIND	8702708
TRAF2	MGC:45012 \| TRAP \| TRAP3	TNF receptor-associated factor 2	-	HPRD,BioGRID	8702708
TRAIP	RNF206 \| TRIP	TRAF interacting protein	-	HPRD,BioGRID	9104814
TRIM37	KIAA0898 \| MUL \| POB1 \| TEF3	tripartite motif-containing 37	-	HPRD,BioGRID	11279055
TUBA3C	TUBA2 \| bA408E5.3	tubulin, alpha 3c	-	HPRD	14743216
USP7	HAUSP \| TEF1	ubiquitin specific peptidase 7 (herpes virus-associated)	-	HPRD,BioGRID	11279055

Pathway annotation

Pathway name	Pathway size	# SZGR genes in pathway	Info
KEGG_PATHWAYS_IN_CANCER	328	259	All SZGR genes in this pathway
KEGG_SMALL_CELL_LUNG_CANCER	84	67	All SZGR genes in this pathway
BIOCARTA_HIVNEF_PATHWAY	58	43	All SZGR genes in this pathway
BIOCARTA_TNFR2_PATHWAY	18	15	All SZGR genes in this pathway
PID_CD40_PATHWAY	31	26	All SZGR genes in this pathway
PID_TNF_PATHWAY	46	33	All SZGR genes in this pathway
PID_HIV_NEF_PATHWAY	35	26	All SZGR genes in this pathway
FULCHER_INFLAMMATORY_RESPONSE_LECTIN_VS_LPS_UP	579	346	All SZGR genes in this pathway
ZHOU_INFLAMMATORY_RESPONSE_LIVE_UP	485	293	All SZGR genes in this pathway
BORCZUK_MALIGNANT_MESOTHELIOMA_DN	104	59	All SZGR genes in this pathway
TAKEDA_TARGETS_OF_NUP98_HOXA9_FUSION_6HR_DN	41	29	All SZGR genes in this pathway
SENESE_HDAC3_TARGETS_UP	501	327	All SZGR genes in this pathway
ZHOU_INFLAMMATORY_RESPONSE_FIMA_UP	544	308	All SZGR genes in this pathway
DUTTA_APOPTOSIS_VIA_NFKB	33	25	All SZGR genes in this pathway
LINDGREN_BLADDER_CANCER_CLUSTER_2B	392	251	All SZGR genes in this pathway
SCHEIDEREIT_IKK_INTERACTING_PROTEINS	58	45	All SZGR genes in this pathway
DIRMEIER_LMP1_RESPONSE_EARLY	66	48	All SZGR genes in this pathway
DIRMEIER_LMP1_RESPONSE_LATE_UP	57	41	All SZGR genes in this pathway
TSAI_RESPONSE_TO_IONIZING_RADIATION	149	101	All SZGR genes in this pathway
NUYTTEN_EZH2_TARGETS_UP	1037	673	All SZGR genes in this pathway
SCIAN_INVERSED_TARGETS_OF_TP53_AND_TP73_DN	31	23	All SZGR genes in this pathway
KOYAMA_SEMA3B_TARGETS_DN	411	249	All SZGR genes in this pathway
ZHANG_RESPONSE_TO_IKK_INHIBITOR_AND_TNF_UP	223	140	All SZGR genes in this pathway
TARTE_PLASMA_CELL_VS_PLASMABLAST_UP	398	262	All SZGR genes in this pathway
GOLDRATH_IMMUNE_MEMORY	65	42	All SZGR genes in this pathway
GALINDO_IMMUNE_RESPONSE_TO_ENTEROTOXIN	85	67	All SZGR genes in this pathway
BASSO_CD40_SIGNALING_UP	101	76	All SZGR genes in this pathway
IVANOVA_HEMATOPOIESIS_STEM_CELL_LONG_TERM	302	191	All SZGR genes in this pathway
BANDRES_RESPONSE_TO_CARMUSTIN_MGMT_24HR_DN	33	21	All SZGR genes in this pathway
GEISS_RESPONSE_TO_DSRNA_UP	38	29	All SZGR genes in this pathway
BANDRES_RESPONSE_TO_CARMUSTIN_MGMT_48HR_DN	161	105	All SZGR genes in this pathway
FOSTER_TOLERANT_MACROPHAGE_DN	409	268	All SZGR genes in this pathway
RAY_TUMORIGENESIS_BY_ERBB2_CDC25A_DN	159	105	All SZGR genes in this pathway
QI_PLASMACYTOMA_UP	259	185	All SZGR genes in this pathway
VILIMAS_NOTCH1_TARGETS_UP	52	41	All SZGR genes in this pathway
LINDSTEDT_DENDRITIC_CELL_MATURATION_B	53	36	All SZGR genes in this pathway
RUTELLA_RESPONSE_TO_CSF2RB_AND_IL4_UP	338	225	All SZGR genes in this pathway
RUTELLA_RESPONSE_TO_HGF_UP	418	282	All SZGR genes in this pathway
RUTELLA_RESPONSE_TO_HGF_VS_CSF2RB_AND_IL4_DN	245	150	All SZGR genes in this pathway
VANASSE_BCL2_TARGETS_DN	74	50	All SZGR genes in this pathway
HINATA_NFKB_TARGETS_KERATINOCYTE_UP	91	63	All SZGR genes in this pathway
POOLA_INVASIVE_BREAST_CANCER_UP	288	168	All SZGR genes in this pathway
TIAN_TNF_SIGNALING_VIA_NFKB	28	21	All SZGR genes in this pathway
WONG_ADULT_TISSUE_STEM_MODULE	721	492	All SZGR genes in this pathway
MIKKELSEN_ES_ICP_WITH_H3K4ME3	718	401	All SZGR genes in this pathway
LI_INDUCED_T_TO_NATURAL_KILLER_UP	307	182	All SZGR genes in this pathway
WIERENGA_STAT5A_TARGETS_UP	217	131	All SZGR genes in this pathway
WIERENGA_STAT5A_TARGETS_GROUP2	60	38	All SZGR genes in this pathway
WANG_TNF_TARGETS	24	17	All SZGR genes in this pathway
FORTSCHEGGER_PHF8_TARGETS_DN	784	464	All SZGR genes in this pathway
PHONG_TNF_RESPONSE_NOT_VIA_P38	337	236	All SZGR genes in this pathway