Search results: The pahtway p2041 has 58 genes in the original annotation. Currently, there are 45 genes in SZGR 2.0 (with evidence in schizophrenia) that are present at this pathway.

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Gene ID Symbol Synonyms Official Full Name Location SZ group ? Functional group ?
1326MAP3K8AURA2 | COT | EST | ESTF | MEKK8 | TPL2 | Tpl-2 | c-COTmitogen-activated protein kinase kinase kinase 810p11.23CV:PGCnp
DMG:Jaffe_2016
Network
3665IRF7IMD39 | IRF-7H | IRF7A | IRF7B | IRF7C | IRF7Hinterferon regulatory factor 711p15.5CV:PGCnp
PMID:cooccur
408ARRB1ARB1 | ARR1arrestin, beta 111q13CV:PGCnp
DMG:Wockner_2014
Network
PMID:cooccur
CompositeSet
Darnell FMRP targets
5970RELANFKB3 | p65v-rel avian reticuloendotheliosis viral oncogene homolog A11q13CV:PGCnp
DNM:Ambalavanan_2016
Network
PMID:cooccur
595CCND1BCL1 | D11S287E | PRAD1 | U21B31cyclin D111q13DMG:Jaffe_2016
Network
PMID:cooccur
472ATMAT1 | ATA | ATC | ATD | ATDC | ATE | TEL1 | TELO1ATM serine/threonine kinase11q22-q23CV:PGCnp
GO_Annotation
GSMA_I
Network
PMID:cooccur
INTRACELLULAR SIGNAL TRANSDUCTION
Ascano FMRP targets
23085ERC1Cast2 | ELKS | ERC-1 | RAB6IP2ELKS/RAB6-interacting/CAST family member 112p13.3CV:GWASdb
CV:PGCnp
GO_Annotation
PROTEIN CLUSTERING
G2Cdb.humanPSD
G2Cdb.humanPSP
CompositeSet
3320HSP90AA1EL52 | HEL-S-65p | HSP86 | HSP89A | HSP90A | HSP90N | HSPC1 | HSPCA | HSPCAL1 | HSPCAL4 | HSPN | Hsp89 | Hsp90 | LAP-2 | LAP2heat shock protein 90kDa alpha family class A member 114q32.33CV:PGCnp
DMG:Nishioka_2013
DMG:Wockner_2014
DNM:Fromer_2014
GO_Annotation
Network
PMID:cooccur
RNA AND PROTEIN SYNTHESIS
CompositeSet
9093DNAJA3HCA57 | TID1 | hTID-1DnaJ heat shock protein family (Hsp40) member A316p13.3CV:GWASdb
CV:PGCnp
Network
G2Cdb.human_BAYES-COLLINS-HUMAN-PSD-FULL
G2Cdb.human_mitochondria
1387CREBBPCBP | KAT3A | RSTSCREB binding protein16p13.3CV:PGCnp
Network
PMID:cooccur
CompositeSet
Darnell FMRP targets
Chromatin Remodeling Genes
1540CYLDBRSS | CDMT | CYLD1 | CYLDI | EAC | MFT | MFT1 | SBS | TEM | USPL2CYLD lysine 63 deubiquitinase16q12.1CV:PGCnp
GSMA_IIE
G2Cdb.human_BAYES-COLLINS-HUMAN-PSD-FULL
G2Cdb.human_BAYES-COLLINS-MOUSE-PSD-CONSENSUS
G2Cdb.humanPSD
G2Cdb.humanPSP
2175FANCAFA | FA-H | FA1 | FAA | FACA | FAH | FANCHFanconi anemia complementation group A16q24.3CV:PGCnp
9020MAP3K14FTDCR1B | HS | HSNIK | NIKmitogen-activated protein kinase kinase kinase 1417q21CV:PGCnp
Network
4215MAP3K3MAPKKK3 | MEKK3mitogen-activated protein kinase kinase kinase 317q23.3CV:PGCnp
Network
PMID:cooccur
Ascano FMRP targets
4854NOTCH3CADASIL | CADASIL1 | CASIL | IMF2 | LMNSnotch 319p13.12CV:PGCnp
GO_Annotation
PMID:cooccur
11140CDC37P50CDC37cell division cycle 3719p13.2CV:PGCnp
DMG:Montano_2016
DMG:Wockner_2014
Network
55620STAP2BKSsignal transducing adaptor family member 219p13.3CV:PGCnp
DNM:Xu_2012
CompositeSet
11184MAP4K1HPK1mitogen-activated protein kinase kinase kinase kinase 119q13.1-q13.4CV:PGCnp
6195RPS6KA1HU-1 | MAPKAPK1A | RSK | RSK1 | p90Rskribosomal protein S6 kinase A11pCV:PGCnp
DMG:Montano_2016
DMG:Nishioka_2013
8915BCL10CARMEN | CIPER | CLAP | IMD37 | c-E10 | mE10B-cell CLL/lymphoma 101p22CV:PGCnp
GO_Annotation
5590PRKCZPKC-ZETA | PKC2protein kinase C zeta1p36.33-p36.2CV:GWAScat
CV:GWASdb
CV:PGCnp
DMG:Wockner_2014
GO_Annotation
Network
INTRACELLULAR SIGNAL TRANSDUCTION
57506MAVSCARDIF | IPS-1 | IPS1 | VISAmitochondrial antiviral signaling protein20p13CV:PGCnp
Expression
26133TRPC4APC20orf188 | PPP1R158 | TRRP4AP | TRUSStransient receptor potential cation channel subfamily C member 4 associated protein20q11.22CV:PGCnpCompositeSet
Darnell FMRP targets
Ascano FMRP targets
6714SRCASV | SRC1 | c-SRC | p60-SrcSRC proto-oncogene, non-receptor tyrosine kinase20q12-q13CV:PGCnp
Network
PMID:cooccur
METABOTROPIC GLUTAMATE RECEPTOR
G2Cdb.human_BAYES-COLLINS-HUMAN-PSD-CONSENSUS
G2Cdb.human_BAYES-COLLINS-HUMAN-PSD-FULL
G2Cdb.human_BAYES-COLLINS-MOUSE-PSD-CONSENSUS
G2Cdb.humanNRC
CompositeSet
Potential synaptic genes
29775CARD10BIMP1 | CARMA3caspase recruitment domain family member 1022q13.1CV:PGCnp
DMG:Montano_2016
2034EPAS1ECYT4 | HIF2A | HLF | MOP2 | PASD2 | bHLHe73endothelial PAS domain protein 12p21-p16CV:PGCnp
DMG:Jaffe_2016
DMG:Wockner_2014
5610EIF2AK2EIF2AK1 | PKR | PPP1R83 | PRKReukaryotic translation initiation factor 2 alpha kinase 22p22-p21CV:PGCnp
PMID:cooccur
10010TANKI-TRAF | ITRAF | TRAF2TRAF family member associated NFKB activator2q24.2CV:PGCnp
DMG:Jaffe_2016
DMG:Wockner_2014
GSMA_IIA
Network
PMID:cooccur
5163PDK1-pyruvate dehydrogenase kinase 12q31.1CV:PGCnp
DMG:Wockner_2014
PMID:cooccur
841CASP8ALPS2B | CAP4 | Casp-8 | FLICE | MACH | MCH5caspase 82q33-q34CV:GWASdb
CV:PGCnp
3667IRS1HIRS-1insulin receptor substrate 12q36CV:PGCnp
DMG:Jaffe_2016
DMG:Montano_2016
DMG:Wockner_2014
DNM:Xu_2012
GSMA_IIA
GSMA_IIE
Network
PMID:cooccur
G2Cdb.humanNRC
G2Cdb.humanPSP
CompositeSet
Ascano FMRP targets
1499CTNNB1CTNNB | MRD19 | armadillocatenin beta 13p21CV:PGCnp
DMG:Jaffe_2016
Network
PMID:cooccur
INTRACELLULAR SIGNAL TRANSDUCTION
G2Cdb.humanNRC
G2Cdb.humanPSD
G2Cdb.humanPSP
CompositeSet
Darnell FMRP targets
Potential synaptic genes
10342TFGHMSNP | SPG57 | TF6 | TRKT3TRK-fused gene3q12.2DNM:Fromer_2014
GO_Annotation
GSMA_IIA
GSMA_IIE
CompositeSet
3064HTTHD | IT15huntingtin4p16.3CV:PGCnp
Network
PMID:cooccur
CompositeSet
Darnell FMRP targets
Ascano FMRP targets
2289FKBP5AIG6 | FKBP51 | FKBP54 | P54 | PPIase | Ptg-10FK506 binding protein 56p21.31CV:PGCnp
GSMA_I
GSMA_IIE
PMID:cooccur
5987TRIM27RFP | RNF76tripartite motif containing 276p22CV:PGCnp
DMG:Jaffe_2016
DMG:Wockner_2014
GO_Annotation
GSMA_I
8737RIPK1RIP | RIP-1 | RIP1receptor interacting serine/threonine kinase 16p25.2CV:PGCnp
DMG:Jaffe_2016
GSMA_I
2309FOXO3AF6q21 | FKHRL1 | FKHRL1P2 | FOXO2 | FOXO3Aforkhead box O36q21CV:PGCnp
DMG:Wockner_2014
Network
CompositeSet
Darnell FMRP targets
10758TRAF3IP2ACT1 | C6orf2 | C6orf4 | C6orf5 | C6orf6 | CANDF8 | CIKS | PSORS13TRAF3 interacting protein 26q21CV:PGCnp
DMG:Wockner_2014
7128TNFAIP3A20 | AISBL | OTUD7C | TNFA1P2TNF alpha induced protein 36q23CV:PGCnp
DMG:Wockner_2014
Ascano FMRP targets
84433CARD11BENTA | BIMP3 | CARMA1 | IMD11 | PPBLcaspase recruitment domain family member 117p22CV:PGCnp
GO_Annotation
83696TRAPPC9IBP | IKBKBBP | MRT13 | NIBP | T1 | TRS120trafficking protein particle complex 98q24.3CV:PGCnp
DMG:Montano_2016
DMG:Wockner_2014
DNM:McCarthy_2014
PMID:cooccur
G2Cdb.human_BAYES-COLLINS-HUMAN-PSD-CONSENSUS
7185TRAF1EBI6 | MGC:10353TNF receptor associated factor 19q33-q34CV:PGCnp
PMID:cooccur
5524PPP2R4PP2A | PR53 | PTPAprotein phosphatase 2A regulatory subunit 49q34CV:PGCnpINTRACELLULAR SIGNAL TRANSDUCTION
7186TRAF2MGC:45012 | TRAP | TRAP3TNF receptor associated factor 29q34CV:PGCnp
Network
PMID:cooccur
Ascano FMRP targets