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Association Linkage Expression Literature GO_Annotation Gene Network miRNA Targets

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Association Linkage Expression Literature GO_Annotation Gene Network miRNA Targets Datasets Gene Ranking

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Gene Page: CREBBP

Summary

GeneID

1387

Symbol

CREBBP

Synonyms

CBP|KAT3A|RSTS

Description

CREB binding protein

Locus tag

Gene type

protein-coding

Map location

16p13.3

Gene in Data Sources

Gene set name

Method of gene set

Evidence

Info

Network

Shortest path distance of core genes in the Human protein-protein interaction network

Contribution to shortest path in PPI network: 0.0553

General Gene Expression (microarray) ?

Gene Expression in Brain Regions (new)

Top co-expressed genes in Brain Regions (new)

Gene

Pearson's Correlation

Spearman's Correlation

Top 10 positively co-expressed genes

C10orf116

0.72

0.82

TAGLN

0.72

0.78

VAMP5

0.71

0.86

MYL9

0.70

0.78

RHOC

0.70

0.74

GSDMD

0.69

0.75

METRN

0.69

0.80

RRAS

0.69

0.81

MUSTN1

0.68

0.80

SERPINB6

0.68

0.78

Top 10 negatively co-expressed genes

RNF214

-0.59

-0.80

TTC3

-0.58

-0.80

NFX1

-0.58

-0.79

TCERG1

-0.58

-0.81

ANKRD17

-0.58

-0.77

TMEM81

-0.58

-0.79

CKAP5

-0.58

-0.79

TOPBP1

-0.58

-0.78

C10orf137

-0.58

-0.79

SMARCC2

-0.58

-0.78

Gene Ontology

Molecular function

GO term

Evidence

Neuro keywords

PubMed ID

GO:0004871

signal transducer activity

TAS

7913207 |8028671

GO:0003677

DNA binding

IEA

GO:0003700

transcription factor activity

TAS

7913207

GO:0003713

transcription coactivator activity

IDA

12435739 |12586840

GO:0003713

transcription coactivator activity

IEA

GO:0003713

transcription coactivator activity

IPI

8684459

GO:0005515

protein binding

IEA

GO:0005524

ATP binding

IEA

GO:0004402

histone acetyltransferase activity

IDA

11742995

GO:0004402

histone acetyltransferase activity

IEA

GO:0016740

transferase activity

IEA

GO:0008270

zinc ion binding

IEA

GO:0016887

ATPase activity

IEA

GO:0016407

acetyltransferase activity

IDA

11742995

GO:0016407

acetyltransferase activity

IEA

GO:0046872

metal ion binding

IEA

GO:0051577

MyoD binding

IDA

8621548

Biological process

GO term

Evidence

Neuro keywords

PubMed ID

GO:0001666

response to hypoxia

TAS

15261140

GO:0006355

regulation of transcription, DNA-dependent

IDA

12169688

GO:0006355

regulation of transcription, DNA-dependent

IEA

GO:0006461

protein complex assembly

TAS

7913207

GO:0007165

signal transduction

NAS

15261140

GO:0018076

N-terminal peptidyl-lysine acetylation

IDA

12435739

GO:0016573

histone acetylation

IDA

11742995

GO:0016573

histone acetylation

IEA

GO:0042592

homeostatic process

NAS

15261140

GO:0045893

positive regulation of transcription, DNA-dependent

IEA

GO:0045941

positive regulation of transcription

IDA

11742995

GO:0045941

positive regulation of transcription

ISS

GO:0044419

interspecies interaction between organisms

IEA

Cellular component

GO term

Evidence

Neuro keywords

PubMed ID

GO:0000123

histone acetyltransferase complex

IEA

GO:0000940

outer kinetochore of condensed chromosome

IEA

GO:0005634

nucleus

12169688

GO:0005634

nucleus

IEA

GO:0005737

cytoplasm

TAS

7913207

GO:0016605

PML body

IDA

17332504

Protein-protein Interactions

Shown by network

Interactors	Aliases B	Official full name B	Experimental	Source	PubMed ID
ABCA1	ABC-1 \| ABC1 \| CERP \| FLJ14958 \| HDLDT1 \| MGC164864 \| MGC165011 \| TGD	ATP-binding cassette, sub-family A (ABC1), member 1	Affinity Capture-Western	BioGRID	11864601
AIRE	AIRE1 \| APECED \| APS1 \| APSI \| PGA1	autoimmune regulator	-	HPRD,BioGRID	10748110
AIRE	AIRE1 \| APECED \| APS1 \| APSI \| PGA1	autoimmune regulator	AIRE isoform 1 interacts with CBP	BIND	10748110
ALX1	CART1	ALX homeobox 1	-	HPRD	12929931
AR	AIS \| DHTR \| HUMARA \| KD \| NR3C4 \| SBMA \| SMAX1 \| TFM	androgen receptor	-	HPRD,BioGRID	9482849
ATF1	EWS-ATF1 \| FUS/ATF-1 \| TREB36	activating transcription factor 1	-	HPRD,BioGRID	8663317
ATF2	CRE-BP1 \| CREB2 \| HB16 \| MGC111558 \| TREB7	activating transcription factor 2	Affinity Capture-Western Reconstituted Complex Two-hybrid	BioGRID	9786917
ATF4	CREB-2 \| CREB2 \| TAXREB67 \| TXREB	activating transcription factor 4 (tax-responsive enhancer element B67)	Reconstituted Complex	BioGRID	9295363
BCL3	BCL4 \| D19S37	B-cell CLL/lymphoma 3	-	HPRD	10497212
BNIP3L	BNIP3a \| NIX	BCL2/adenovirus E1B 19kDa interacting protein 3-like	CBP interacts with Bnip3L.	BIND	15607964
BRCA1	BRCAI \| BRCC1 \| IRIS \| PSCP \| RNF53	breast cancer 1, early onset	-	HPRD,BioGRID	10655477
BRCA1	BRCAI \| BRCC1 \| IRIS \| PSCP \| RNF53	breast cancer 1, early onset	CBP interacts with BRCA1. This interaction was modelled on a demonstrated interaction between human BRCA1 and mouse CBP.	BIND	10655477
CCNC	CycC	cyclin C	Co-fractionation	BioGRID	9710619
CCND1	BCL1 \| D11S287E \| PRAD1 \| U21B31	cyclin D1	CBP interacts with cyclin D1 promoter.	BIND	15808510
CDC25B	-	cell division cycle 25 homolog B (S. pombe)	-	HPRD	11689696
CDK8	K35 \| MGC126074 \| MGC126075	cyclin-dependent kinase 8	Affinity Capture-Western Co-fractionation	BioGRID	9710619
CDKN1A	CAP20 \| CDKN1 \| CIP1 \| MDA-6 \| P21 \| SDI1 \| WAF1 \| p21CIP1	cyclin-dependent kinase inhibitor 1A (p21, Cip1)	CREBBP (CBP) interacts with the p21 promoter.	BIND	15710329
CDKN1A	CAP20 \| CDKN1 \| CIP1 \| MDA-6 \| P21 \| SDI1 \| WAF1 \| p21CIP1	cyclin-dependent kinase inhibitor 1A (p21, Cip1)	CBP interacts with p21.	BIND	10764767
CDX2	CDX-3 \| CDX3	caudal type homeobox 2	-	HPRD,BioGRID	10066780
CITED1	MSG1	Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 1	-	HPRD,BioGRID	10722728
CITED2	MRG1 \| P35SRJ	Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2	-	HPRD,BioGRID	9887100
CREB1	CREB \| MGC9284	cAMP responsive element binding protein 1	CREB1 (CREB) interacts with CREBBP (CBP).	BIND	16007092
			CBP interacts with CREB.	BIND	15454081
			-	HPRD,BioGRID	9413984
CREBBP	CBP \| KAT3A \| RSTS	CREB binding protein	-	HPRD	11259575
CSK	MGC117393	c-src tyrosine kinase	-	HPRD,BioGRID	10801129
CSNK2A1	CK2A1 \| CKII	casein kinase 2, alpha 1 polypeptide	-	HPRD,BioGRID	9685505
CSNK2A2	CK2A2 \| CSNK2A1 \| FLJ43934	casein kinase 2, alpha prime polypeptide	-	HPRD,BioGRID	9685505
CTBP1	BARS \| MGC104684	C-terminal binding protein 1	CTBP1 interacts with CREBBP (CBP)	BIND	15834423
CTNNB1	CTNNB \| DKFZp686D02253 \| FLJ25606 \| FLJ37923	catenin (cadherin-associated protein), beta 1, 88kDa	Phenotypic Enhancement	BioGRID	15782138
CUX1	CASP \| CDP \| CDP/Cut \| CDP1 \| COY1 \| CUTL1 \| CUX \| Clox \| Cux/CDP \| GOLIM6 \| Nbla10317 \| p100 \| p110 \| p200 \| p75	cut-like homeobox 1	-	HPRD,BioGRID	10852958
DAXX	BING2 \| DAP6 \| EAP1 \| MGC126245 \| MGC126246	death-domain associated protein	CBP interacts with Daxx.	BIND	11799127
DDX5	DKFZp686J01190 \| G17P1 \| HLR1 \| HUMP68 \| p68	DEAD (Asp-Glu-Ala-Asp) box polypeptide 5	-	HPRD,BioGRID	12527917
E2F1	E2F-1 \| RBAP1 \| RBBP3 \| RBP3	E2F transcription factor 1	Two-hybrid	BioGRID	12748276
E2F3	DKFZp686C18211 \| E2F-3 \| KIAA0075 \| MGC104598	E2F transcription factor 3	Two-hybrid	BioGRID	12748276
EBF1	COE1 \| EBF \| FLJ39389 \| FLJ41763 \| O/E-1 \| OLF1	early B-cell factor 1	-	HPRD,BioGRID	12748286
EGR1	AT225 \| G0S30 \| KROX-24 \| NGFI-A \| TIS8 \| ZIF-268 \| ZNF225	early growth response 1	-	HPRD,BioGRID	9806899
			CBP interacts with Egr1 promoter.	BIND	15225550
			CBP promoter interacts with Egr1.	BIND	15225550
ESR1	DKFZp686N23123 \| ER \| ESR \| ESRA \| Era \| NR3A1	estrogen receptor 1	Affinity Capture-Western Reconstituted Complex	BioGRID	11113179 \|11782371
EVI1	AML1-EVI-1 \| EVI-1 \| MDS1-EVI1 \| MGC163392 \| PRDM3	ecotropic viral integration site 1	-	HPRD,BioGRID	11568182
EWSR1	EWS	Ewing sarcoma breakpoint region 1	-	HPRD,BioGRID	12459554
FOS	AP-1 \| C-FOS	v-fos FBJ murine osteosarcoma viral oncogene homolog	Reconstituted Complex	BioGRID	11782371
FOXO1	FKH1 \| FKHR \| FOXO1A	forkhead box O1	-	HPRD,BioGRID	10973497
FOXO4	AFX \| AFX1 \| MGC120490 \| MLLT7	forkhead box O4	-	HPRD,BioGRID	10973497
GATA1	ERYF1 \| GF-1 \| GF1 \| NFE1	GATA binding protein 1 (globin transcription factor 1)	Reconstituted Complex	BioGRID	12496368
GLI3	ACLS \| GCPS \| PAP-A \| PAPA \| PAPA1 \| PAPB \| PHS \| PPDIV	GLI-Kruppel family member GLI3	Affinity Capture-Western Reconstituted Complex	BioGRID	10075717
GTF2B	TF2B \| TFIIB	general transcription factor IIB	Reconstituted Complex	BioGRID	11782371 \|11864601
H3F3A	H3.3A \| H3F3 \| MGC87782 \| MGC87783	H3 histone, family 3A	H3F3A (Histone 3) interacts with CREBBP (CBP).	BIND	15616580
HIF1A	HIF-1alpha \| HIF1 \| HIF1-ALPHA \| MOP1 \| PASD8	hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)	-	HPRD,BioGRID	10202154
HIPK2	DKFZp686K02111 \| FLJ23711 \| PRO0593	homeodomain interacting protein kinase 2	-	HPRD,BioGRID	11740489
HNF1A	HNF1 \| LFB1 \| MODY3 \| TCF1	HNF1 homeobox A	CBP interacts with the HNF-1 gene.	BIND	15616580
HNF1A	HNF1 \| LFB1 \| MODY3 \| TCF1	HNF1 homeobox A	-	HPRD,BioGRID	10777539
HNF4A	FLJ39654 \| HNF4 \| HNF4a7 \| HNF4a8 \| HNF4a9 \| MODY \| MODY1 \| NR2A1 \| NR2A21 \| TCF \| TCF14	hepatocyte nuclear factor 4, alpha	CBP interacts with the HNF-4 gene.	BIND	15616580
HNF4A		hepatocyte nuclear factor 4, alpha	-	HPRD,BioGRID	9434765 \|10085149
HOXB7	HHO.C1 \| HOX2 \| HOX2C \| Hox-2.3	homeobox B7	-	HPRD,BioGRID	10435624
HSF1	HSTF1	heat shock transcription factor 1	HSF1 interacts with CBP. This interaction was modeled on a demonstrated interaction between human HSF1 and CBP from an unspecified species.	BIND	14960326
HTT	HD \| IT15	huntingtin	CBP interacts with htt. This interaction was modeled on a demonstrated interaction between CBP and htt from unspecified species.	BIND	10823891
			-	HPRD,BioGRID	11264541
			Htt interacts with CBP.	BIND	15225551
ICAM1	BB2 \| CD54 \| P3.58	intercellular adhesion molecule 1	CREBBP (CBP) interacts with the ICAM1 promoter.	BIND	15829968
ING1	p24ING1c \| p33 \| p33ING1 \| p33ING1b \| p47 \| p47ING1a	inhibitor of growth family, member 1	Affinity Capture-Western	BioGRID	12015309
IRF3	-	interferon regulatory factor 3	IRF-3 interacts with CBP.	BIND	15502848
IRF3	-	interferon regulatory factor 3	-	HPRD,BioGRID	10521456
JDP2	JUNDM2	Jun dimerization protein 2	-	HPRD	12101239
JUN	AP-1 \| AP1 \| c-Jun	jun oncogene	-	HPRD,BioGRID	2138276 \|9786917
KAT2B	CAF \| P \| P/CAF \| PCAF	K(lysine) acetyltransferase 2B	Affinity Capture-Western Co-fractionation Reconstituted Complex	BioGRID	9710619 \|11864601
KHDRBS1	FLJ34027 \| Sam68 \| p62	KH domain containing, RNA binding, signal transduction associated 1	-	HPRD,BioGRID	12496368
KLF1	EKLF	Kruppel-like factor 1 (erythroid)	Biochemical Activity	BioGRID	11259590
KLF13	BTEB3 \| FKLF2 \| NSLP1 \| RFLAT-1 \| RFLAT1	Kruppel-like factor 13	Affinity Capture-Western Biochemical Activity Phenotypic Enhancement	BioGRID	11748222
KLF4	EZF \| GKLF	Kruppel-like factor 4 (gut)	-	HPRD,BioGRID	10666450
KLF5	BTEB2 \| CKLF \| IKLF	Kruppel-like factor 5 (intestinal)	-	HPRD,BioGRID	12682370
MAF	MGC71685 \| c-MAF	v-maf musculoaponeurotic fibrosarcoma oncogene homolog (avian)	-	HPRD,BioGRID	11943779
MAF	MGC71685 \| c-MAF		CBP interacts with c-Maf. This interaction was modeled on a demonstrated interaction between CBP and c-Maf from unspecified sources.	BIND	11943779
MAFG	MGC13090 \| MGC20149	v-maf musculoaponeurotic fibrosarcoma oncogene homolog G (avian)	-	HPRD	11154691
MAML1	KIAA0200 \| Mam-1 \| Mam1	mastermind-like 1 (Drosophila)	-	HPRD,BioGRID	12050117
MBD2	DKFZp586O0821 \| DMTase \| NY-CO-41	methyl-CpG binding domain protein 2	-	HPRD	12665568
MED21	SRB7 \| SURB7	mediator complex subunit 21	Affinity Capture-Western	BioGRID	9710619
MGMT	-	O-6-methylguanine-DNA methyltransferase	-	HPRD,BioGRID	11564893
MLL	ALL-1 \| CXXC7 \| FLJ11783 \| HRX \| HTRX1 \| KMT2A \| MLL/GAS7 \| MLL1A \| TET1-MLL \| TRX1	myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila)	-	HPRD,BioGRID	11259575 \|12205094
MSX1	HOX7 \| HYD1	msh homeobox 1	-	HPRD,BioGRID	10215616 \|11115394
MYB	Cmyb \| c-myb \| c-myb_CDS \| efg	v-myb myeloblastosis viral oncogene homolog (avian)	-	HPRD,BioGRID	12196545
MYBL2	B-MYB \| BMYB \| MGC15600	v-myb myeloblastosis viral oncogene homolog (avian)-like 2	-	HPRD,BioGRID	11423988
MYOD1	MYF3 \| MYOD \| PUM \| bHLHc1	myogenic differentiation 1	Affinity Capture-Western Phenotypic Enhancement Reconstituted Complex	BioGRID	9001254 \|11463815
MYOD1	MYF3 \| MYOD \| PUM \| bHLHc1	myogenic differentiation 1	-	HPRD	2176177 \|9238849 \|11463815
N4BP2	B3BP \| FLJ10680 \| KIAA1413	NEDD4 binding protein 2	-	HPRD,BioGRID	12730195
NAP1L1	FLJ16112 \| MGC23410 \| MGC8688 \| NAP1 \| NAP1L \| NRP	nucleosome assembly protein 1-like 1	CREBBP (CBP) interacts with NAP1L1 (NAP-1).	BIND	11940655
NCOA1	F-SRC-1 \| KAT13A \| MGC129719 \| MGC129720 \| NCoA-1 \| RIP160 \| SRC-1 \| SRC1 \| bHLHe42	nuclear receptor coactivator 1	Affinity Capture-MS Biochemical Activity Reconstituted Complex Two-hybrid	BioGRID	11113179 \|11971985 \|15027889
NCOA1		nuclear receptor coactivator 1	-	HPRD	11003650 \|11113179
NCOA3	ACTR \| AIB-1 \| AIB1 \| CAGH16 \| CTG26 \| KAT13B \| MGC141848 \| RAC3 \| SRC3 \| TNRC14 \| TNRC16 \| TRAM-1 \| pCIP	nuclear receptor coactivator 3	Affinity Capture-MS Co-fractionation Two-hybrid	BioGRID	11076796 \|11971985
			ACTR interacts with CBP. This interaction was modeled on a demonstrated interaction between human ACTR and CBP from an unspecified species.	BIND	9267036
			SRC-3 interacts with CBP. This interaction was modelled on a demonstrated interaction between human SRC-3 and CBP from an unspecified species.	BIND	15383283
			CBP interacts with TRAM-1. This interaction was modelled on a demonstrated interaction between mouse CBP and human TRAM-1.	BIND	9346901
			-	HPRD	9445475 \|11823864
NCOA6	AIB3 \| ANTP \| ASC2 \| HOX1.1 \| HOXA7 \| KIAA0181 \| NRC \| PRIP \| RAP250 \| TRBP	nuclear receptor coactivator 6	Reconstituted Complex Two-hybrid	BioGRID	10567404 \|11158331
NEUROG1	AKA \| Math4C \| NEUROD3 \| bHLHa6 \| ngn1	neurogenin 1	-	HPRD,BioGRID	11239394
NFATC2	KIAA0611 \| NFAT1 \| NFATP	nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2	-	HPRD,BioGRID	9625762
NFATC4	NF-ATc4 \| NFAT3	nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4	-	HPRD,BioGRID	11514544
NFE2	NF-E2 \| p45	nuclear factor (erythroid-derived 2), 45kDa	Affinity Capture-Western Biochemical Activity Reconstituted Complex	BioGRID	11154691
NFE2L2	NRF2	nuclear factor (erythroid-derived 2)-like 2	-	HPRD,BioGRID	11683914
NKX2-1	BCH \| BHC \| NK-2 \| NKX2.1 \| NKX2A \| TEBP \| TITF1 \| TTF-1 \| TTF1	NK2 homeobox 1	Two-hybrid	BioGRID	11076796
NLK	DKFZp761G1211 \| FLJ21033	nemo-like kinase	-	HPRD	14720327
NPAS2	FLJ23138 \| MGC71151 \| MOP4 \| PASD4 \| bHLHe9	neuronal PAS domain protein 2	Reconstituted Complex	BioGRID	14645221
NR3C1	GCCR \| GCR \| GR \| GRL	nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)	-	HPRD,BioGRID	9649342
NUP98	ADIR2 \| NUP196 \| NUP96	nucleoporin 98kDa	-	HPRD,BioGRID	9858599
ONECUT1	HNF-6 \| HNF6 \| HNF6A	one cut homeobox 1	-	HPRD,BioGRID	10811635
PAX5	BSAP	paired box 5	CBP interacts with Pax5.	BIND	11799127
PELP1	HMX3 \| MNAR \| P160	proline, glutamate and leucine rich protein 1	-	HPRD,BioGRID	11481323
PHOX2A	ARIX \| CFEOM2 \| FEOM2 \| MGC52227 \| NCAM2 \| PMX2A	paired-like homeobox 2a	-	HPRD,BioGRID	10644760
PIAS3	FLJ14651 \| ZMIZ5	protein inhibitor of activated STAT, 3	Affinity Capture-Western	BioGRID	14691252
PML	MYL \| PP8675 \| RNF71 \| TRIM19	promyelocytic leukemia	-	HPRD	10077561 \|10610177 \|12142048 \|12234245 \|12622724
PML	MYL \| PP8675 \| RNF71 \| TRIM19	promyelocytic leukemia	Affinity Capture-Western Reconstituted Complex	BioGRID	10077561 \|10610177 \|12622724
POLR2A	MGC75453 \| POLR2 \| POLRA \| RPB1 \| RPBh1 \| RPO2 \| RPOL2 \| RpIILS \| hRPB220 \| hsRPB1	polymerase (RNA) II (DNA directed) polypeptide A, 220kDa	-	HPRD,BioGRID	9710619
PPARG	NR1C3 \| PPARG1 \| PPARG2 \| PPARgamma	peroxisome proliferator-activated receptor gamma	Reconstituted Complex	BioGRID	10848596
PROX1	-	prospero homeobox 1	-	HPRD	11943779
PTMA	MGC104802 \| TMSA	prothymosin, alpha	-	HPRD,BioGRID	11897665
RBBP4	NURF55 \| RBAP48	retinoblastoma binding protein 4	-	HPRD,BioGRID	10866654
RBBP7	MGC138867 \| MGC138868 \| RbAp46	retinoblastoma binding protein 7	Reconstituted Complex	BioGRID	10866654
RELA	MGC131774 \| NFKB3 \| p65	v-rel reticuloendotheliosis viral oncogene homolog A (avian)	-	HPRD,BioGRID	9548485
			CBP interacts with p65.	BIND	9096323
			RELA (NF-kappaB p65) interacts with CREBBP (CBP).	BIND	16007092
RPA2	REPA2 \| RPA32	replication protein A2, 32kDa	Affinity Capture-Western	BioGRID	17525332
RPS6KA1	HU-1 \| MAPKAPK1A \| RSK \| RSK1	ribosomal protein S6 kinase, 90kDa, polypeptide 1	-	HPRD	8756728
RPS6KA2	HU-2 \| MAPKAPK1C \| RSK \| RSK3 \| S6K-alpha \| S6K-alpha2 \| p90-RSK3 \| pp90RSK3	ribosomal protein S6 kinase, 90kDa, polypeptide 2	Affinity Capture-Western	BioGRID	8756728
RPS6KA3	CLS \| HU-3 \| ISPK-1 \| MAPKAPK1B \| MRX19 \| RSK \| RSK2 \| S6K-alpha3 \| p90-RSK2 \| pp90RSK2	ribosomal protein S6 kinase, 90kDa, polypeptide 3	-	HPRD,BioGRID	11564891
SERTAD1	SEI1 \| TRIP-Br1	SERTA domain containing 1	-	HPRD,BioGRID	12736710
SMAD1	BSP1 \| JV4-1 \| JV41 \| MADH1 \| MADR1	SMAD family member 1	Affinity Capture-Western	BioGRID	10673036 \|11239394
SMAD2	JV18 \| JV18-1 \| MADH2 \| MADR2 \| MGC22139 \| MGC34440 \| hMAD-2 \| hSMAD2	SMAD family member 2	CBP interacts with Smad2. This interaction was modeled on a demonstrated interaction between mouse CBP and Smad2 from an unspecified species.	BIND	15750622
SMAD2		SMAD family member 2	CBP interacts with Smad2. This interaction was modeled on a demonstrated interaction between CBP from an unspecified species and human Smad2.	BIND	9679056
SMAD3	DKFZp586N0721 \| DKFZp686J10186 \| HSPC193 \| HsT17436 \| JV15-2 \| MADH3 \| MGC60396	SMAD family member 3	CBP interacts with Smad3. This interaction was modeled on a demonstrated interaction between mouse CBP and Smad3 from an unspecified species.	BIND	15750622
SMARCA4	BAF190 \| BRG1 \| FLJ39786 \| SNF2 \| SNF2-BETA \| SNF2L4 \| SNF2LB \| SWI2 \| hSNF2b	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4	Phenotypic Enhancement	BioGRID	11003650
SMARCB1	BAF47 \| INI1 \| RDT \| SNF5 \| SNF5L1 \| Sfh1p \| Snr1 \| hSNFS	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1	Affinity Capture-Western Co-fractionation	BioGRID	9710619
SNIP1	FLJ12553 \| RP3-423B22.3 \| dJ423B22.2	Smad nuclear interacting protein 1	-	HPRD,BioGRID	10887155
SRCAP	DOMO1 \| EAF1 \| FLJ44499 \| KIAA0309 \| SWR1	Snf2-related CREBBP activator protein	-	HPRD	10347196 \|11581372
SREBF1	SREBP-1c \| SREBP1 \| bHLHd1	sterol regulatory element binding transcription factor 1	Affinity Capture-Western Far Western	BioGRID	8918891
SREBF2	SREBP2 \| bHLHd2	sterol regulatory element binding transcription factor 2	-	HPRD,BioGRID	8918891
SRF	MCM1	serum response factor (c-fos serum response element-binding transcription factor)	Affinity Capture-Western	BioGRID	12622724
SS18L1	CREST \| KIAA0693 \| LP2261 \| MGC26711 \| MGC78386	synovial sarcoma translocation gene on chromosome 18-like 1	-	HPRD,BioGRID	14716005
STAT1	DKFZp686B04100 \| ISGF-3 \| STAT91	signal transducer and activator of transcription 1, 91kDa	Stat1-beta interacts with CBP.	BIND	8986769
			Stat1-alpha interacts with CBP.	BIND	8986769
			-	HPRD,BioGRID	8986769
STAT2	ISGF-3 \| MGC59816 \| P113 \| STAT113	signal transducer and activator of transcription 2, 113kDa	-	HPRD,BioGRID	8848048 \|10464260
STAT3	APRF \| FLJ20882 \| HIES \| MGC16063	signal transducer and activator of transcription 3 (acute-phase response factor)	Affinity Capture-Western	BioGRID	11239394
STAT3	APRF \| FLJ20882 \| HIES \| MGC16063		Stat3 was acetylated by CBP. This interaction was modeled on a demonstrated interaction between human Stat3 and CBP from an unspecified species.	BIND	15653507
STAT6	D12S1644 \| IL-4-STAT \| STAT6B \| STAT6C	signal transducer and activator of transcription 6, interleukin-4 induced	-	HPRD,BioGRID	10454341 \|11574547
TACC2	AZU-1 \| ECTACC	transforming, acidic coiled-coil containing protein 2	TACC2 interacts with CBP.	BIND	14767476
TCF12	HEB \| HTF4 \| HsT17266 \| bHLHb20	transcription factor 12	HEBa interacts with CBP. This interaction was modeled on a demonstrated interaction between HEBb and CBP.	BIND	15333839
TCF12	HEB \| HTF4 \| HsT17266 \| bHLHb20	transcription factor 12	HEBb interacts with CBP.	BIND	15333839
TCF3	E2A \| ITF1 \| MGC129647 \| MGC129648 \| bHLHb21	transcription factor 3 (E2A immunoglobulin enhancer binding factors E12/E47)	-	HPRD,BioGRID	12435739
TDG	-	thymine-DNA glycosylase	-	HPRD,BioGRID	11864601
TFF1	BCEI \| D21S21 \| HP1.A \| HPS2 \| pNR-2 \| pS2	trefoil factor 1	CBP interacts with pS2.	BIND	10490106
TGS1	DKFZp762A163 \| FLJ22995 \| NCOA6IP \| PIMT \| PIPMT	trimethylguanosine synthase homolog (S. cerevisiae)	-	HPRD,BioGRID	11912212
TNFSF10	APO2L \| Apo-2L \| CD253 \| TL2 \| TRAIL	tumor necrosis factor (ligand) superfamily, member 10	CBP interacts with the TNFSF10 promoter.	BIND	15619633
TP53	FLJ92943 \| LFS1 \| TRP53 \| p53	tumor protein p53	-	HPRD,BioGRID	10848610 \|11782467
TP53	FLJ92943 \| LFS1 \| TRP53 \| p53	tumor protein p53	p53 interacts with CBP. This interaction was modeled on a demonstrated interaction between human p53 and CBP from an unspecified species.	BIND	10823891
TRAM2	KIAA0057	translocation associated membrane protein 2	-	HPRD	14612417
TRERF1	BCAR2 \| FLJ21198 \| HSA277276 \| RAPA \| RP1-139D8.5 \| TReP-132 \| dJ139D8.5	transcriptional regulating factor 1	-	HPRD,BioGRID	11349124
TRIP4	HsT17391	thyroid hormone receptor interactor 4	-	HPRD,BioGRID	10454579
XRCC6	CTC75 \| CTCBF \| G22P1 \| KU70 \| ML8 \| TLAA	X-ray repair complementing defective repair in Chinese hamster cells 6	Reconstituted Complex Two-hybrid	BioGRID	9488450
YWHAH	YWHA1	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta polypeptide	-	HPRD	11266503

Pathway annotation

Pathway name	Pathway size	# SZGR genes in pathway	Info
KEGG_CELL_CYCLE	128	84	All SZGR genes in this pathway
KEGG_WNT_SIGNALING_PATHWAY	151	112	All SZGR genes in this pathway
KEGG_NOTCH_SIGNALING_PATHWAY	47	35	All SZGR genes in this pathway
KEGG_TGF_BETA_SIGNALING_PATHWAY	86	64	All SZGR genes in this pathway
KEGG_ADHERENS_JUNCTION	75	53	All SZGR genes in this pathway
KEGG_JAK_STAT_SIGNALING_PATHWAY	155	105	All SZGR genes in this pathway
KEGG_LONG_TERM_POTENTIATION	70	57	All SZGR genes in this pathway
KEGG_MELANOGENESIS	102	80	All SZGR genes in this pathway
KEGG_HUNTINGTONS_DISEASE	185	109	All SZGR genes in this pathway
KEGG_PATHWAYS_IN_CANCER	328	259	All SZGR genes in this pathway
KEGG_RENAL_CELL_CARCINOMA	70	60	All SZGR genes in this pathway
KEGG_PROSTATE_CANCER	89	75	All SZGR genes in this pathway
BIOCARTA_RELA_PATHWAY	16	12	All SZGR genes in this pathway
BIOCARTA_CSK_PATHWAY	24	20	All SZGR genes in this pathway
BIOCARTA_CARM_ER_PATHWAY	35	27	All SZGR genes in this pathway
BIOCARTA_VDR_PATHWAY	12	7	All SZGR genes in this pathway
BIOCARTA_SET_PATHWAY	11	6	All SZGR genes in this pathway
BIOCARTA_IL7_PATHWAY	17	14	All SZGR genes in this pathway
BIOCARTA_PPARA_PATHWAY	58	43	All SZGR genes in this pathway
BIOCARTA_PITX2_PATHWAY	15	15	All SZGR genes in this pathway
BIOCARTA_NFAT_PATHWAY	56	45	All SZGR genes in this pathway
BIOCARTA_NTHI_PATHWAY	24	20	All SZGR genes in this pathway
BIOCARTA_PML_PATHWAY	17	12	All SZGR genes in this pathway
BIOCARTA_TGFB_PATHWAY	19	14	All SZGR genes in this pathway
BIOCARTA_CARM1_PATHWAY	13	11	All SZGR genes in this pathway
BIOCARTA_WNT_PATHWAY	26	24	All SZGR genes in this pathway
ST_DIFFERENTIATION_PATHWAY_IN_PC12_CELLS	45	35	All SZGR genes in this pathway
PID_SMAD2_3NUCLEAR_PATHWAY	82	63	All SZGR genes in this pathway
PID_HDAC_CLASSIII_PATHWAY	25	20	All SZGR genes in this pathway
PID_E2F_PATHWAY	74	48	All SZGR genes in this pathway
PID_HIF2PATHWAY	34	29	All SZGR genes in this pathway
PID_MYC_ACTIV_PATHWAY	79	62	All SZGR genes in this pathway
PID_PS1_PATHWAY	46	39	All SZGR genes in this pathway
PID_TCPTP_PATHWAY	43	33	All SZGR genes in this pathway
PID_HDAC_CLASSI_PATHWAY	66	50	All SZGR genes in this pathway
PID_NFAT_3PATHWAY	54	47	All SZGR genes in this pathway
PID_REG_GR_PATHWAY	82	60	All SZGR genes in this pathway
PID_FOXO_PATHWAY	49	43	All SZGR genes in this pathway
PID_AJDISS_2PATHWAY	48	38	All SZGR genes in this pathway
PID_P53_DOWNSTREAM_PATHWAY	137	94	All SZGR genes in this pathway
PID_AR_TF_PATHWAY	53	38	All SZGR genes in this pathway
PID_IFNG_PATHWAY	40	34	All SZGR genes in this pathway
PID_FOXM1_PATHWAY	40	30	All SZGR genes in this pathway
PID_CMYB_PATHWAY	84	61	All SZGR genes in this pathway
PID_RETINOIC_ACID_PATHWAY	30	23	All SZGR genes in this pathway
PID_HEDGEHOG_GLI_PATHWAY	48	35	All SZGR genes in this pathway
PID_KIT_PATHWAY	52	40	All SZGR genes in this pathway
PID_HIF1_TFPATHWAY	66	52	All SZGR genes in this pathway
PID_P53_REGULATION_PATHWAY	59	50	All SZGR genes in this pathway
PID_RB_1PATHWAY	65	46	All SZGR genes in this pathway
PID_HNF3A_PATHWAY	44	29	All SZGR genes in this pathway
PID_HES_HEY_PATHWAY	48	39	All SZGR genes in this pathway
PID_IL12_STAT4_PATHWAY	33	29	All SZGR genes in this pathway
REACTOME_DEVELOPMENTAL_BIOLOGY	396	292	All SZGR genes in this pathway
REACTOME_BMAL1_CLOCK_NPAS2_ACTIVATES_CIRCADIAN_EXPRESSION	36	27	All SZGR genes in this pathway
REACTOME_PPARA_ACTIVATES_GENE_EXPRESSION	104	72	All SZGR genes in this pathway
REACTOME_PRE_NOTCH_TRANSCRIPTION_AND_TRANSLATION	29	17	All SZGR genes in this pathway
REACTOME_RORA_ACTIVATES_CIRCADIAN_EXPRESSION	24	17	All SZGR genes in this pathway
REACTOME_YAP1_AND_WWTR1_TAZ_STIMULATED_GENE_EXPRESSION	24	16	All SZGR genes in this pathway
REACTOME_PRE_NOTCH_EXPRESSION_AND_PROCESSING	44	24	All SZGR genes in this pathway
REACTOME_NOTCH1_INTRACELLULAR_DOMAIN_REGULATES_TRANSCRIPTION	46	28	All SZGR genes in this pathway
REACTOME_CIRCADIAN_REPRESSION_OF_EXPRESSION_BY_REV_ERBA	23	16	All SZGR genes in this pathway
REACTOME_SIGNALING_BY_NOTCH1	70	46	All SZGR genes in this pathway
REACTOME_REGULATION_OF_HYPOXIA_INDUCIBLE_FACTOR_HIF_BY_OXYGEN	25	17	All SZGR genes in this pathway
REACTOME_GENERIC_TRANSCRIPTION_PATHWAY	352	181	All SZGR genes in this pathway
REACTOME_NOTCH_HLH_TRANSCRIPTION_PATHWAY	13	8	All SZGR genes in this pathway
REACTOME_METABOLISM_OF_LIPIDS_AND_LIPOPROTEINS	478	302	All SZGR genes in this pathway
REACTOME_FATTY_ACID_TRIACYLGLYCEROL_AND_KETONE_BODY_METABOLISM	168	115	All SZGR genes in this pathway
REACTOME_TRAF6_MEDIATED_IRF7_ACTIVATION	30	26	All SZGR genes in this pathway
REACTOME_CIRCADIAN_CLOCK	53	40	All SZGR genes in this pathway
REACTOME_FACTORS_INVOLVED_IN_MEGAKARYOCYTE_DEVELOPMENT_AND_PLATELET_PRODUCTION	132	101	All SZGR genes in this pathway
REACTOME_TRAF3_DEPENDENT_IRF_ACTIVATION_PATHWAY	14	10	All SZGR genes in this pathway
REACTOME_RIG_I_MDA5_MEDIATED_INDUCTION_OF_IFN_ALPHA_BETA_PATHWAYS	73	57	All SZGR genes in this pathway
REACTOME_TRANSCRIPTIONAL_REGULATION_OF_WHITE_ADIPOCYTE_DIFFERENTIATION	72	53	All SZGR genes in this pathway
REACTOME_SIGNALING_BY_NOTCH	103	64	All SZGR genes in this pathway
REACTOME_HEMOSTASIS	466	331	All SZGR genes in this pathway
REACTOME_INNATE_IMMUNE_SYSTEM	279	178	All SZGR genes in this pathway
REACTOME_IMMUNE_SYSTEM	933	616	All SZGR genes in this pathway
BORCZUK_MALIGNANT_MESOTHELIOMA_UP	305	185	All SZGR genes in this pathway
GARGALOVIC_RESPONSE_TO_OXIDIZED_PHOSPHOLIPIDS_BLUE_UP	136	80	All SZGR genes in this pathway
KOKKINAKIS_METHIONINE_DEPRIVATION_48HR_UP	128	95	All SZGR genes in this pathway
KOKKINAKIS_METHIONINE_DEPRIVATION_96HR_UP	117	84	All SZGR genes in this pathway
GRAESSMANN_APOPTOSIS_BY_DOXORUBICIN_DN	1781	1082	All SZGR genes in this pathway
SCHLOSSER_SERUM_RESPONSE_DN	712	443	All SZGR genes in this pathway
SCHEIDEREIT_IKK_INTERACTING_PROTEINS	58	45	All SZGR genes in this pathway
DACOSTA_UV_RESPONSE_VIA_ERCC3_DN	855	609	All SZGR genes in this pathway
DACOSTA_UV_RESPONSE_VIA_ERCC3_COMMON_DN	483	336	All SZGR genes in this pathway
PUJANA_BREAST_CANCER_LIT_INT_NETWORK	101	73	All SZGR genes in this pathway
BUYTAERT_PHOTODYNAMIC_THERAPY_STRESS_UP	811	508	All SZGR genes in this pathway
LOPEZ_MBD_TARGETS	957	597	All SZGR genes in this pathway
SCHAEFFER_PROSTATE_DEVELOPMENT_6HR_DN	514	330	All SZGR genes in this pathway
SMITH_TERT_TARGETS_UP	145	91	All SZGR genes in this pathway
FLECHNER_BIOPSY_KIDNEY_TRANSPLANT_OK_VS_DONOR_UP	555	346	All SZGR genes in this pathway
THEILGAARD_NEUTROPHIL_AT_SKIN_WOUND_DN	225	163	All SZGR genes in this pathway
CUI_TCF21_TARGETS_2_DN	830	547	All SZGR genes in this pathway
BLALOCK_ALZHEIMERS_DISEASE_UP	1691	1088	All SZGR genes in this pathway
DAZARD_RESPONSE_TO_UV_NHEK_DN	318	220	All SZGR genes in this pathway
KRASNOSELSKAYA_ILF3_TARGETS_DN	46	38	All SZGR genes in this pathway
DURCHDEWALD_SKIN_CARCINOGENESIS_DN	264	168	All SZGR genes in this pathway
MONNIER_POSTRADIATION_TUMOR_ESCAPE_UP	393	244	All SZGR genes in this pathway
SANSOM_APC_MYC_TARGETS	217	138	All SZGR genes in this pathway
SANSOM_APC_TARGETS_REQUIRE_MYC	210	123	All SZGR genes in this pathway
KYNG_DNA_DAMAGE_BY_GAMMA_AND_UV_RADIATION	88	65	All SZGR genes in this pathway
KYNG_DNA_DAMAGE_DN	195	135	All SZGR genes in this pathway
IWANAGA_CARCINOGENESIS_BY_KRAS_UP	170	107	All SZGR genes in this pathway
ACEVEDO_LIVER_CANCER_UP	973	570	All SZGR genes in this pathway
BONOME_OVARIAN_CANCER_SURVIVAL_SUBOPTIMAL_DEBULKING	510	309	All SZGR genes in this pathway
GRADE_COLON_CANCER_UP	871	505	All SZGR genes in this pathway
GRESHOCK_CANCER_COPY_NUMBER_UP	323	240	All SZGR genes in this pathway
ROME_INSULIN_TARGETS_IN_MUSCLE_DN	204	114	All SZGR genes in this pathway
PLASARI_TGFB1_SIGNALING_VIA_NFIC_1HR_DN	106	77	All SZGR genes in this pathway

miRNA Targets ?

miRNA family	Target position			miRNA ID	miRNA seq
miRNA family	UTR start	UTR end	Match method	miRNA ID	miRNA seq
miR-137	759	765	m8	hsa-miR-137	UAUUGCUUAAGAAUACGCGUAG
miR-153	996	1002	m8	hsa-miR-153	UUGCAUAGUCACAAAAGUGA
miR-186	1079	1085	1A	hsa-miR-186	CAAAGAAUUCUCCUUUUGGGCUU
miR-200bc/429	518	525	1A,m8	hsa-miR-200b	UAAUACUGCCUGGUAAUGAUGAC
				hsa-miR-200c	UAAUACUGCCGGGUAAUGAUGG
				hsa-miR-429	UAAUACUGUCUGGUAAAACCGU
miR-23	737	743	1A	hsa-miR-23a^brain	AUCACAUUGCCAGGGAUUUCC
miR-23	737	743	1A	hsa-miR-23b^brain	AUCACAUUGCCAGGGAUUACC
miR-26	744	750	1A	hsa-miR-26a^brain	UUCAAGUAAUCCAGGAUAGGC
				hsa-miR-26b^SZ	UUCAAGUAAUUCAGGAUAGGUU
				hsa-miR-26a^brain	UUCAAGUAAUCCAGGAUAGGC
				hsa-miR-26b^SZ	UUCAAGUAAUUCAGGAUAGGUU
miR-30-3p	49	56	1A,m8	hsa-miR-30a-3p	CUUUCAGUCGGAUGUUUGCAGC
miR-30-3p	49	56	1A,m8	hsa-miR-30e-3p	CUUUCAGUCGGAUGUUUACAGC
miR-330	634	640	m8	hsa-miR-330^brain	GCAAAGCACACGGCCUGCAGAGA
miR-361	645	652	1A,m8	hsa-miR-361^brain	UUAUCAGAAUCUCCAGGGGUAC
miR-376c	734	740	m8	hsa-miR-376c	AACAUAGAGGAAAUUCCACG
miR-381	1018	1024	1A	hsa-miR-381	UAUACAAGGGCAAGCUCUCUGU
miR-410	1121	1127	1A	hsa-miR-410	AAUAUAACACAGAUGGCCUGU
miR-488	183	189	m8	hsa-miR-488	CCCAGAUAAUGGCACUCUCAA
miR-493-5p	923	929	m8	hsa-miR-493-5p	UUGUACAUGGUAGGCUUUCAUU
miR-495	158	164	1A	hsa-miR-495^brain	AAACAAACAUGGUGCACUUCUUU
miR-495	158	164	1A	hsa-miR-495^brain	AAACAAACAUGGUGCACUUCUUU
miR-543	1098	1104	m8	hsa-miR-543	AAACAUUCGCGGUGCACUUCU
miR-543	1098	1104	m8	hsa-miR-543	AAACAUUCGCGGUGCACUUCU

SZ: miRNAs which differentially expressed in brain cortex of schizophrenia patients comparing with control samples using microarray. Click here to see the list of SZ related miRNAs.
Brain: miRNAs which are expressed in brain based on miRNA microarray expression studies. Click here to see the list of brain related miRNAs.