Gene Page: CREBBP
Summary ?
GeneID | 1387 |
Symbol | CREBBP |
Synonyms | CBP|KAT3A|RSTS |
Description | CREB binding protein |
Reference | MIM:600140|HGNC:HGNC:2348|Ensembl:ENSG00000005339|HPRD:02534|Vega:OTTHUMG00000129431 |
Gene type | protein-coding |
Map location | 16p13.3 |
Pascal p-value | 0.019 |
Sherlock p-value | 0.399 |
Fetal beta | 1.687 |
Support | CompositeSet Darnell FMRP targets Chromatin Remodeling Genes |
Gene in Data Sources
Gene set name | Method of gene set | Description | Info |
---|---|---|---|
CV:PGCnp | Genome-wide Association Study | GWAS | |
PMID:cooccur | High-throughput literature-search | Systematic search in PubMed for genes co-occurring with SCZ keywords. A total of 3027 genes were included. | |
Literature | High-throughput literature-search | Co-occurance with Schizophrenia keywords: schizophrenia,schizophrenias | Click to show details |
Network | Shortest path distance of core genes in the Human protein-protein interaction network | Contribution to shortest path in PPI network: 0.0553 |
Section I. Genetics and epigenetics annotation
Section II. Transcriptome annotation
General gene expression (GTEx)
Gene expression during devlopment (BrainCloud)
Footnote:
A total of 269 time points ploted, with n=38 fetal samples (x=1:38). Each triangle represents one time point.
Gene expression of temporal and spatial changes (BrainSpan)
Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes the lower 25% and upper 25% of the expression distribution.
Top co-expressed genes in brain regions
Top 10 positively co-expressed genes | ||
Gene | Pearson's Correlation | Spearman's Correlation |
C10orf116 | 0.72 | 0.82 |
TAGLN | 0.72 | 0.78 |
VAMP5 | 0.71 | 0.86 |
MYL9 | 0.70 | 0.78 |
RHOC | 0.70 | 0.74 |
GSDMD | 0.69 | 0.75 |
METRN | 0.69 | 0.80 |
RRAS | 0.69 | 0.81 |
MUSTN1 | 0.68 | 0.80 |
SERPINB6 | 0.68 | 0.78 |
Top 10 negatively co-expressed genes | ||
Gene | Pearson's Correlation | Spearman's Correlation |
RNF214 | -0.59 | -0.80 |
TTC3 | -0.58 | -0.80 |
NFX1 | -0.58 | -0.79 |
TCERG1 | -0.58 | -0.81 |
ANKRD17 | -0.58 | -0.77 |
TMEM81 | -0.58 | -0.79 |
CKAP5 | -0.58 | -0.79 |
TOPBP1 | -0.58 | -0.78 |
C10orf137 | -0.58 | -0.79 |
SMARCC2 | -0.58 | -0.78 |
Section III. Gene Ontology annotation
Molecular function | GO term | Evidence | Neuro keywords | PubMed ID |
---|---|---|---|---|
GO:0004871 | signal transducer activity | TAS | 7913207 |8028671 | |
GO:0003677 | DNA binding | IEA | - | |
GO:0003700 | transcription factor activity | TAS | 7913207 | |
GO:0003713 | transcription coactivator activity | IDA | 12435739 |12586840 | |
GO:0003713 | transcription coactivator activity | IEA | - | |
GO:0003713 | transcription coactivator activity | IPI | 8684459 | |
GO:0005515 | protein binding | IEA | - | |
GO:0005524 | ATP binding | IEA | - | |
GO:0004402 | histone acetyltransferase activity | IDA | 11742995 | |
GO:0004402 | histone acetyltransferase activity | IEA | - | |
GO:0016740 | transferase activity | IEA | - | |
GO:0008270 | zinc ion binding | IEA | - | |
GO:0016887 | ATPase activity | IEA | - | |
GO:0016407 | acetyltransferase activity | IDA | 11742995 | |
GO:0016407 | acetyltransferase activity | IEA | - | |
GO:0046872 | metal ion binding | IEA | - | |
GO:0051577 | MyoD binding | IDA | 8621548 | |
Biological process | GO term | Evidence | Neuro keywords | PubMed ID |
GO:0001666 | response to hypoxia | TAS | 15261140 | |
GO:0006355 | regulation of transcription, DNA-dependent | IDA | 12169688 | |
GO:0006355 | regulation of transcription, DNA-dependent | IEA | - | |
GO:0006461 | protein complex assembly | TAS | 7913207 | |
GO:0007165 | signal transduction | NAS | 15261140 | |
GO:0018076 | N-terminal peptidyl-lysine acetylation | IDA | 12435739 | |
GO:0016573 | histone acetylation | IDA | 11742995 | |
GO:0016573 | histone acetylation | IEA | - | |
GO:0042592 | homeostatic process | NAS | 15261140 | |
GO:0045893 | positive regulation of transcription, DNA-dependent | IEA | - | |
GO:0045941 | positive regulation of transcription | IDA | 11742995 | |
GO:0045941 | positive regulation of transcription | ISS | - | |
GO:0044419 | interspecies interaction between organisms | IEA | - | |
Cellular component | GO term | Evidence | Neuro keywords | PubMed ID |
GO:0000123 | histone acetyltransferase complex | IEA | - | |
GO:0000940 | outer kinetochore of condensed chromosome | IEA | - | |
GO:0005634 | nucleus | IC | 12169688 | |
GO:0005634 | nucleus | IEA | - | |
GO:0005737 | cytoplasm | TAS | 7913207 | |
GO:0016605 | PML body | IDA | 17332504 |
Section IV. Protein-protein interaction annotation
Interactors | Aliases B | Official full name B | Experimental | Source | PubMed ID |
---|---|---|---|---|---|
ABCA1 | ABC-1 | ABC1 | CERP | FLJ14958 | HDLDT1 | MGC164864 | MGC165011 | TGD | ATP-binding cassette, sub-family A (ABC1), member 1 | Affinity Capture-Western | BioGRID | 11864601 |
AIRE | AIRE1 | APECED | APS1 | APSI | PGA1 | autoimmune regulator | - | HPRD,BioGRID | 10748110 |
AIRE | AIRE1 | APECED | APS1 | APSI | PGA1 | autoimmune regulator | AIRE isoform 1 interacts with CBP | BIND | 10748110 |
ALX1 | CART1 | ALX homeobox 1 | - | HPRD | 12929931 |
AR | AIS | DHTR | HUMARA | KD | NR3C4 | SBMA | SMAX1 | TFM | androgen receptor | - | HPRD,BioGRID | 9482849 |
ATF1 | EWS-ATF1 | FUS/ATF-1 | TREB36 | activating transcription factor 1 | - | HPRD,BioGRID | 8663317 |
ATF2 | CRE-BP1 | CREB2 | HB16 | MGC111558 | TREB7 | activating transcription factor 2 | Affinity Capture-Western Reconstituted Complex Two-hybrid | BioGRID | 9786917 |
ATF4 | CREB-2 | CREB2 | TAXREB67 | TXREB | activating transcription factor 4 (tax-responsive enhancer element B67) | Reconstituted Complex | BioGRID | 9295363 |
BCL3 | BCL4 | D19S37 | B-cell CLL/lymphoma 3 | - | HPRD | 10497212 |
BNIP3L | BNIP3a | NIX | BCL2/adenovirus E1B 19kDa interacting protein 3-like | CBP interacts with Bnip3L. | BIND | 15607964 |
BRCA1 | BRCAI | BRCC1 | IRIS | PSCP | RNF53 | breast cancer 1, early onset | - | HPRD,BioGRID | 10655477 |
BRCA1 | BRCAI | BRCC1 | IRIS | PSCP | RNF53 | breast cancer 1, early onset | CBP interacts with BRCA1. This interaction was modelled on a demonstrated interaction between human BRCA1 and mouse CBP. | BIND | 10655477 |
CCNC | CycC | cyclin C | Co-fractionation | BioGRID | 9710619 |
CCND1 | BCL1 | D11S287E | PRAD1 | U21B31 | cyclin D1 | CBP interacts with cyclin D1 promoter. | BIND | 15808510 |
CDC25B | - | cell division cycle 25 homolog B (S. pombe) | - | HPRD | 11689696 |
CDK8 | K35 | MGC126074 | MGC126075 | cyclin-dependent kinase 8 | Affinity Capture-Western Co-fractionation | BioGRID | 9710619 |
CDKN1A | CAP20 | CDKN1 | CIP1 | MDA-6 | P21 | SDI1 | WAF1 | p21CIP1 | cyclin-dependent kinase inhibitor 1A (p21, Cip1) | CREBBP (CBP) interacts with the p21 promoter. | BIND | 15710329 |
CDKN1A | CAP20 | CDKN1 | CIP1 | MDA-6 | P21 | SDI1 | WAF1 | p21CIP1 | cyclin-dependent kinase inhibitor 1A (p21, Cip1) | CBP interacts with p21. | BIND | 10764767 |
CDX2 | CDX-3 | CDX3 | caudal type homeobox 2 | - | HPRD,BioGRID | 10066780 |
CITED1 | MSG1 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 1 | - | HPRD,BioGRID | 10722728 |
CITED2 | MRG1 | P35SRJ | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 | - | HPRD,BioGRID | 9887100 |
CREB1 | CREB | MGC9284 | cAMP responsive element binding protein 1 | CREB1 (CREB) interacts with CREBBP (CBP). | BIND | 16007092 |
CREB1 | CREB | MGC9284 | cAMP responsive element binding protein 1 | CBP interacts with CREB. | BIND | 15454081 |
CREB1 | CREB | MGC9284 | cAMP responsive element binding protein 1 | - | HPRD,BioGRID | 9413984 |
CREBBP | CBP | KAT3A | RSTS | CREB binding protein | - | HPRD | 11259575 |
CSK | MGC117393 | c-src tyrosine kinase | - | HPRD,BioGRID | 10801129 |
CSNK2A1 | CK2A1 | CKII | casein kinase 2, alpha 1 polypeptide | - | HPRD,BioGRID | 9685505 |
CSNK2A2 | CK2A2 | CSNK2A1 | FLJ43934 | casein kinase 2, alpha prime polypeptide | - | HPRD,BioGRID | 9685505 |
CTBP1 | BARS | MGC104684 | C-terminal binding protein 1 | CTBP1 interacts with CREBBP (CBP) | BIND | 15834423 |
CTNNB1 | CTNNB | DKFZp686D02253 | FLJ25606 | FLJ37923 | catenin (cadherin-associated protein), beta 1, 88kDa | Phenotypic Enhancement | BioGRID | 15782138 |
CUX1 | CASP | CDP | CDP/Cut | CDP1 | COY1 | CUTL1 | CUX | Clox | Cux/CDP | GOLIM6 | Nbla10317 | p100 | p110 | p200 | p75 | cut-like homeobox 1 | - | HPRD,BioGRID | 10852958 |
DAXX | BING2 | DAP6 | EAP1 | MGC126245 | MGC126246 | death-domain associated protein | CBP interacts with Daxx. | BIND | 11799127 |
DDX5 | DKFZp686J01190 | G17P1 | HLR1 | HUMP68 | p68 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 5 | - | HPRD,BioGRID | 12527917 |
E2F1 | E2F-1 | RBAP1 | RBBP3 | RBP3 | E2F transcription factor 1 | Two-hybrid | BioGRID | 12748276 |
E2F3 | DKFZp686C18211 | E2F-3 | KIAA0075 | MGC104598 | E2F transcription factor 3 | Two-hybrid | BioGRID | 12748276 |
EBF1 | COE1 | EBF | FLJ39389 | FLJ41763 | O/E-1 | OLF1 | early B-cell factor 1 | - | HPRD,BioGRID | 12748286 |
EGR1 | AT225 | G0S30 | KROX-24 | NGFI-A | TIS8 | ZIF-268 | ZNF225 | early growth response 1 | - | HPRD,BioGRID | 9806899 |
EGR1 | AT225 | G0S30 | KROX-24 | NGFI-A | TIS8 | ZIF-268 | ZNF225 | early growth response 1 | CBP interacts with Egr1 promoter. | BIND | 15225550 |
EGR1 | AT225 | G0S30 | KROX-24 | NGFI-A | TIS8 | ZIF-268 | ZNF225 | early growth response 1 | CBP promoter interacts with Egr1. | BIND | 15225550 |
ESR1 | DKFZp686N23123 | ER | ESR | ESRA | Era | NR3A1 | estrogen receptor 1 | Affinity Capture-Western Reconstituted Complex | BioGRID | 11113179 |11782371 |
EVI1 | AML1-EVI-1 | EVI-1 | MDS1-EVI1 | MGC163392 | PRDM3 | ecotropic viral integration site 1 | - | HPRD,BioGRID | 11568182 |
EWSR1 | EWS | Ewing sarcoma breakpoint region 1 | - | HPRD,BioGRID | 12459554 |
FOS | AP-1 | C-FOS | v-fos FBJ murine osteosarcoma viral oncogene homolog | Reconstituted Complex | BioGRID | 11782371 |
FOXO1 | FKH1 | FKHR | FOXO1A | forkhead box O1 | - | HPRD,BioGRID | 10973497 |
FOXO4 | AFX | AFX1 | MGC120490 | MLLT7 | forkhead box O4 | - | HPRD,BioGRID | 10973497 |
GATA1 | ERYF1 | GF-1 | GF1 | NFE1 | GATA binding protein 1 (globin transcription factor 1) | Reconstituted Complex | BioGRID | 12496368 |
GLI3 | ACLS | GCPS | PAP-A | PAPA | PAPA1 | PAPB | PHS | PPDIV | GLI-Kruppel family member GLI3 | Affinity Capture-Western Reconstituted Complex | BioGRID | 10075717 |
GTF2B | TF2B | TFIIB | general transcription factor IIB | Reconstituted Complex | BioGRID | 11782371 |11864601 |
H3F3A | H3.3A | H3F3 | MGC87782 | MGC87783 | H3 histone, family 3A | H3F3A (Histone 3) interacts with CREBBP (CBP). | BIND | 15616580 |
HIF1A | HIF-1alpha | HIF1 | HIF1-ALPHA | MOP1 | PASD8 | hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | - | HPRD,BioGRID | 10202154 |
HIPK2 | DKFZp686K02111 | FLJ23711 | PRO0593 | homeodomain interacting protein kinase 2 | - | HPRD,BioGRID | 11740489 |
HNF1A | HNF1 | LFB1 | MODY3 | TCF1 | HNF1 homeobox A | CBP interacts with the HNF-1 gene. | BIND | 15616580 |
HNF1A | HNF1 | LFB1 | MODY3 | TCF1 | HNF1 homeobox A | - | HPRD,BioGRID | 10777539 |
HNF4A | FLJ39654 | HNF4 | HNF4a7 | HNF4a8 | HNF4a9 | MODY | MODY1 | NR2A1 | NR2A21 | TCF | TCF14 | hepatocyte nuclear factor 4, alpha | CBP interacts with the HNF-4 gene. | BIND | 15616580 |
HNF4A | FLJ39654 | HNF4 | HNF4a7 | HNF4a8 | HNF4a9 | MODY | MODY1 | NR2A1 | NR2A21 | TCF | TCF14 | hepatocyte nuclear factor 4, alpha | - | HPRD,BioGRID | 9434765 |10085149 |
HOXB7 | HHO.C1 | HOX2 | HOX2C | Hox-2.3 | homeobox B7 | - | HPRD,BioGRID | 10435624 |
HSF1 | HSTF1 | heat shock transcription factor 1 | HSF1 interacts with CBP. This interaction was modeled on a demonstrated interaction between human HSF1 and CBP from an unspecified species. | BIND | 14960326 |
HTT | HD | IT15 | huntingtin | CBP interacts with htt. This interaction was modeled on a demonstrated interaction between CBP and htt from unspecified species. | BIND | 10823891 |
HTT | HD | IT15 | huntingtin | - | HPRD,BioGRID | 11264541 |
HTT | HD | IT15 | huntingtin | Htt interacts with CBP. | BIND | 15225551 |
ICAM1 | BB2 | CD54 | P3.58 | intercellular adhesion molecule 1 | CREBBP (CBP) interacts with the ICAM1 promoter. | BIND | 15829968 |
ING1 | p24ING1c | p33 | p33ING1 | p33ING1b | p47 | p47ING1a | inhibitor of growth family, member 1 | Affinity Capture-Western | BioGRID | 12015309 |
IRF3 | - | interferon regulatory factor 3 | IRF-3 interacts with CBP. | BIND | 15502848 |
IRF3 | - | interferon regulatory factor 3 | - | HPRD,BioGRID | 10521456 |
JDP2 | JUNDM2 | Jun dimerization protein 2 | - | HPRD | 12101239 |
JUN | AP-1 | AP1 | c-Jun | jun oncogene | - | HPRD,BioGRID | 2138276 |9786917 |
KAT2B | CAF | P | P/CAF | PCAF | K(lysine) acetyltransferase 2B | Affinity Capture-Western Co-fractionation Reconstituted Complex | BioGRID | 9710619 |11864601 |
KHDRBS1 | FLJ34027 | Sam68 | p62 | KH domain containing, RNA binding, signal transduction associated 1 | - | HPRD,BioGRID | 12496368 |
KLF1 | EKLF | Kruppel-like factor 1 (erythroid) | Biochemical Activity | BioGRID | 11259590 |
KLF13 | BTEB3 | FKLF2 | NSLP1 | RFLAT-1 | RFLAT1 | Kruppel-like factor 13 | Affinity Capture-Western Biochemical Activity Phenotypic Enhancement | BioGRID | 11748222 |
KLF4 | EZF | GKLF | Kruppel-like factor 4 (gut) | - | HPRD,BioGRID | 10666450 |
KLF5 | BTEB2 | CKLF | IKLF | Kruppel-like factor 5 (intestinal) | - | HPRD,BioGRID | 12682370 |
MAF | MGC71685 | c-MAF | v-maf musculoaponeurotic fibrosarcoma oncogene homolog (avian) | - | HPRD,BioGRID | 11943779 |
MAF | MGC71685 | c-MAF | v-maf musculoaponeurotic fibrosarcoma oncogene homolog (avian) | CBP interacts with c-Maf. This interaction was modeled on a demonstrated interaction between CBP and c-Maf from unspecified sources. | BIND | 11943779 |
MAFG | MGC13090 | MGC20149 | v-maf musculoaponeurotic fibrosarcoma oncogene homolog G (avian) | - | HPRD | 11154691 |
MAML1 | KIAA0200 | Mam-1 | Mam1 | mastermind-like 1 (Drosophila) | - | HPRD,BioGRID | 12050117 |
MBD2 | DKFZp586O0821 | DMTase | NY-CO-41 | methyl-CpG binding domain protein 2 | - | HPRD | 12665568 |
MED21 | SRB7 | SURB7 | mediator complex subunit 21 | Affinity Capture-Western | BioGRID | 9710619 |
MGMT | - | O-6-methylguanine-DNA methyltransferase | - | HPRD,BioGRID | 11564893 |
MLL | ALL-1 | CXXC7 | FLJ11783 | HRX | HTRX1 | KMT2A | MLL/GAS7 | MLL1A | TET1-MLL | TRX1 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila) | - | HPRD,BioGRID | 11259575 |12205094 |
MSX1 | HOX7 | HYD1 | msh homeobox 1 | - | HPRD,BioGRID | 10215616 |11115394 |
MYB | Cmyb | c-myb | c-myb_CDS | efg | v-myb myeloblastosis viral oncogene homolog (avian) | - | HPRD,BioGRID | 12196545 |
MYBL2 | B-MYB | BMYB | MGC15600 | v-myb myeloblastosis viral oncogene homolog (avian)-like 2 | - | HPRD,BioGRID | 11423988 |
MYOD1 | MYF3 | MYOD | PUM | bHLHc1 | myogenic differentiation 1 | Affinity Capture-Western Phenotypic Enhancement Reconstituted Complex | BioGRID | 9001254 |11463815 |
MYOD1 | MYF3 | MYOD | PUM | bHLHc1 | myogenic differentiation 1 | - | HPRD | 2176177 |9238849 |11463815 |
N4BP2 | B3BP | FLJ10680 | KIAA1413 | NEDD4 binding protein 2 | - | HPRD,BioGRID | 12730195 |
NAP1L1 | FLJ16112 | MGC23410 | MGC8688 | NAP1 | NAP1L | NRP | nucleosome assembly protein 1-like 1 | CREBBP (CBP) interacts with NAP1L1 (NAP-1). | BIND | 11940655 |
NCOA1 | F-SRC-1 | KAT13A | MGC129719 | MGC129720 | NCoA-1 | RIP160 | SRC-1 | SRC1 | bHLHe42 | nuclear receptor coactivator 1 | Affinity Capture-MS Biochemical Activity Reconstituted Complex Two-hybrid | BioGRID | 11113179 |11971985 |15027889 |
NCOA1 | F-SRC-1 | KAT13A | MGC129719 | MGC129720 | NCoA-1 | RIP160 | SRC-1 | SRC1 | bHLHe42 | nuclear receptor coactivator 1 | - | HPRD | 11003650 |11113179 |
NCOA3 | ACTR | AIB-1 | AIB1 | CAGH16 | CTG26 | KAT13B | MGC141848 | RAC3 | SRC3 | TNRC14 | TNRC16 | TRAM-1 | pCIP | nuclear receptor coactivator 3 | Affinity Capture-MS Co-fractionation Two-hybrid | BioGRID | 11076796 |11971985 |
NCOA3 | ACTR | AIB-1 | AIB1 | CAGH16 | CTG26 | KAT13B | MGC141848 | RAC3 | SRC3 | TNRC14 | TNRC16 | TRAM-1 | pCIP | nuclear receptor coactivator 3 | ACTR interacts with CBP. This interaction was modeled on a demonstrated interaction between human ACTR and CBP from an unspecified species. | BIND | 9267036 |
NCOA3 | ACTR | AIB-1 | AIB1 | CAGH16 | CTG26 | KAT13B | MGC141848 | RAC3 | SRC3 | TNRC14 | TNRC16 | TRAM-1 | pCIP | nuclear receptor coactivator 3 | SRC-3 interacts with CBP. This interaction was modelled on a demonstrated interaction between human SRC-3 and CBP from an unspecified species. | BIND | 15383283 |
NCOA3 | ACTR | AIB-1 | AIB1 | CAGH16 | CTG26 | KAT13B | MGC141848 | RAC3 | SRC3 | TNRC14 | TNRC16 | TRAM-1 | pCIP | nuclear receptor coactivator 3 | CBP interacts with TRAM-1. This interaction was modelled on a demonstrated interaction between mouse CBP and human TRAM-1. | BIND | 9346901 |
NCOA3 | ACTR | AIB-1 | AIB1 | CAGH16 | CTG26 | KAT13B | MGC141848 | RAC3 | SRC3 | TNRC14 | TNRC16 | TRAM-1 | pCIP | nuclear receptor coactivator 3 | - | HPRD | 9445475 |11823864 |
NCOA6 | AIB3 | ANTP | ASC2 | HOX1.1 | HOXA7 | KIAA0181 | NRC | PRIP | RAP250 | TRBP | nuclear receptor coactivator 6 | Reconstituted Complex Two-hybrid | BioGRID | 10567404 |11158331 |
NEUROG1 | AKA | Math4C | NEUROD3 | bHLHa6 | ngn1 | neurogenin 1 | - | HPRD,BioGRID | 11239394 |
NFATC2 | KIAA0611 | NFAT1 | NFATP | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 | - | HPRD,BioGRID | 9625762 |
NFATC4 | NF-ATc4 | NFAT3 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4 | - | HPRD,BioGRID | 11514544 |
NFE2 | NF-E2 | p45 | nuclear factor (erythroid-derived 2), 45kDa | Affinity Capture-Western Biochemical Activity Reconstituted Complex | BioGRID | 11154691 |
NFE2L2 | NRF2 | nuclear factor (erythroid-derived 2)-like 2 | - | HPRD,BioGRID | 11683914 |
NKX2-1 | BCH | BHC | NK-2 | NKX2.1 | NKX2A | TEBP | TITF1 | TTF-1 | TTF1 | NK2 homeobox 1 | Two-hybrid | BioGRID | 11076796 |
NLK | DKFZp761G1211 | FLJ21033 | nemo-like kinase | - | HPRD | 14720327 |
NPAS2 | FLJ23138 | MGC71151 | MOP4 | PASD4 | bHLHe9 | neuronal PAS domain protein 2 | Reconstituted Complex | BioGRID | 14645221 |
NR3C1 | GCCR | GCR | GR | GRL | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | - | HPRD,BioGRID | 9649342 |
NUP98 | ADIR2 | NUP196 | NUP96 | nucleoporin 98kDa | - | HPRD,BioGRID | 9858599 |
ONECUT1 | HNF-6 | HNF6 | HNF6A | one cut homeobox 1 | - | HPRD,BioGRID | 10811635 |
PAX5 | BSAP | paired box 5 | CBP interacts with Pax5. | BIND | 11799127 |
PELP1 | HMX3 | MNAR | P160 | proline, glutamate and leucine rich protein 1 | - | HPRD,BioGRID | 11481323 |
PHOX2A | ARIX | CFEOM2 | FEOM2 | MGC52227 | NCAM2 | PMX2A | paired-like homeobox 2a | - | HPRD,BioGRID | 10644760 |
PIAS3 | FLJ14651 | ZMIZ5 | protein inhibitor of activated STAT, 3 | Affinity Capture-Western | BioGRID | 14691252 |
PML | MYL | PP8675 | RNF71 | TRIM19 | promyelocytic leukemia | - | HPRD | 10077561 |10610177 |12142048 |12234245 |12622724 |
PML | MYL | PP8675 | RNF71 | TRIM19 | promyelocytic leukemia | Affinity Capture-Western Reconstituted Complex | BioGRID | 10077561 |10610177 |12622724 |
POLR2A | MGC75453 | POLR2 | POLRA | RPB1 | RPBh1 | RPO2 | RPOL2 | RpIILS | hRPB220 | hsRPB1 | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | - | HPRD,BioGRID | 9710619 |
PPARG | NR1C3 | PPARG1 | PPARG2 | PPARgamma | peroxisome proliferator-activated receptor gamma | Reconstituted Complex | BioGRID | 10848596 |
PROX1 | - | prospero homeobox 1 | - | HPRD | 11943779 |
PTMA | MGC104802 | TMSA | prothymosin, alpha | - | HPRD,BioGRID | 11897665 |
RBBP4 | NURF55 | RBAP48 | retinoblastoma binding protein 4 | - | HPRD,BioGRID | 10866654 |
RBBP7 | MGC138867 | MGC138868 | RbAp46 | retinoblastoma binding protein 7 | Reconstituted Complex | BioGRID | 10866654 |
RELA | MGC131774 | NFKB3 | p65 | v-rel reticuloendotheliosis viral oncogene homolog A (avian) | - | HPRD,BioGRID | 9548485 |
RELA | MGC131774 | NFKB3 | p65 | v-rel reticuloendotheliosis viral oncogene homolog A (avian) | CBP interacts with p65. | BIND | 9096323 |
RELA | MGC131774 | NFKB3 | p65 | v-rel reticuloendotheliosis viral oncogene homolog A (avian) | RELA (NF-kappaB p65) interacts with CREBBP (CBP). | BIND | 16007092 |
RPA2 | REPA2 | RPA32 | replication protein A2, 32kDa | Affinity Capture-Western | BioGRID | 17525332 |
RPS6KA1 | HU-1 | MAPKAPK1A | RSK | RSK1 | ribosomal protein S6 kinase, 90kDa, polypeptide 1 | - | HPRD | 8756728 |
RPS6KA2 | HU-2 | MAPKAPK1C | RSK | RSK3 | S6K-alpha | S6K-alpha2 | p90-RSK3 | pp90RSK3 | ribosomal protein S6 kinase, 90kDa, polypeptide 2 | Affinity Capture-Western | BioGRID | 8756728 |
RPS6KA3 | CLS | HU-3 | ISPK-1 | MAPKAPK1B | MRX19 | RSK | RSK2 | S6K-alpha3 | p90-RSK2 | pp90RSK2 | ribosomal protein S6 kinase, 90kDa, polypeptide 3 | - | HPRD,BioGRID | 11564891 |
SERTAD1 | SEI1 | TRIP-Br1 | SERTA domain containing 1 | - | HPRD,BioGRID | 12736710 |
SMAD1 | BSP1 | JV4-1 | JV41 | MADH1 | MADR1 | SMAD family member 1 | Affinity Capture-Western | BioGRID | 10673036 |11239394 |
SMAD2 | JV18 | JV18-1 | MADH2 | MADR2 | MGC22139 | MGC34440 | hMAD-2 | hSMAD2 | SMAD family member 2 | CBP interacts with Smad2. This interaction was modeled on a demonstrated interaction between mouse CBP and Smad2 from an unspecified species. | BIND | 15750622 |
SMAD2 | JV18 | JV18-1 | MADH2 | MADR2 | MGC22139 | MGC34440 | hMAD-2 | hSMAD2 | SMAD family member 2 | CBP interacts with Smad2. This interaction was modeled on a demonstrated interaction between CBP from an unspecified species and human Smad2. | BIND | 9679056 |
SMAD3 | DKFZp586N0721 | DKFZp686J10186 | HSPC193 | HsT17436 | JV15-2 | MADH3 | MGC60396 | SMAD family member 3 | CBP interacts with Smad3. This interaction was modeled on a demonstrated interaction between mouse CBP and Smad3 from an unspecified species. | BIND | 15750622 |
SMARCA4 | BAF190 | BRG1 | FLJ39786 | SNF2 | SNF2-BETA | SNF2L4 | SNF2LB | SWI2 | hSNF2b | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 | Phenotypic Enhancement | BioGRID | 11003650 |
SMARCB1 | BAF47 | INI1 | RDT | SNF5 | SNF5L1 | Sfh1p | Snr1 | hSNFS | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1 | Affinity Capture-Western Co-fractionation | BioGRID | 9710619 |
SNIP1 | FLJ12553 | RP3-423B22.3 | dJ423B22.2 | Smad nuclear interacting protein 1 | - | HPRD,BioGRID | 10887155 |
SRCAP | DOMO1 | EAF1 | FLJ44499 | KIAA0309 | SWR1 | Snf2-related CREBBP activator protein | - | HPRD | 10347196 |11581372 |
SREBF1 | SREBP-1c | SREBP1 | bHLHd1 | sterol regulatory element binding transcription factor 1 | Affinity Capture-Western Far Western | BioGRID | 8918891 |
SREBF2 | SREBP2 | bHLHd2 | sterol regulatory element binding transcription factor 2 | - | HPRD,BioGRID | 8918891 |
SRF | MCM1 | serum response factor (c-fos serum response element-binding transcription factor) | Affinity Capture-Western | BioGRID | 12622724 |
SS18L1 | CREST | KIAA0693 | LP2261 | MGC26711 | MGC78386 | synovial sarcoma translocation gene on chromosome 18-like 1 | - | HPRD,BioGRID | 14716005 |
STAT1 | DKFZp686B04100 | ISGF-3 | STAT91 | signal transducer and activator of transcription 1, 91kDa | Stat1-beta interacts with CBP. | BIND | 8986769 |
STAT1 | DKFZp686B04100 | ISGF-3 | STAT91 | signal transducer and activator of transcription 1, 91kDa | Stat1-alpha interacts with CBP. | BIND | 8986769 |
STAT1 | DKFZp686B04100 | ISGF-3 | STAT91 | signal transducer and activator of transcription 1, 91kDa | - | HPRD,BioGRID | 8986769 |
STAT2 | ISGF-3 | MGC59816 | P113 | STAT113 | signal transducer and activator of transcription 2, 113kDa | - | HPRD,BioGRID | 8848048 |10464260 |
STAT3 | APRF | FLJ20882 | HIES | MGC16063 | signal transducer and activator of transcription 3 (acute-phase response factor) | Affinity Capture-Western | BioGRID | 11239394 |
STAT3 | APRF | FLJ20882 | HIES | MGC16063 | signal transducer and activator of transcription 3 (acute-phase response factor) | Stat3 was acetylated by CBP. This interaction was modeled on a demonstrated interaction between human Stat3 and CBP from an unspecified species. | BIND | 15653507 |
STAT6 | D12S1644 | IL-4-STAT | STAT6B | STAT6C | signal transducer and activator of transcription 6, interleukin-4 induced | - | HPRD,BioGRID | 10454341 |11574547 |
TACC2 | AZU-1 | ECTACC | transforming, acidic coiled-coil containing protein 2 | TACC2 interacts with CBP. | BIND | 14767476 |
TCF12 | HEB | HTF4 | HsT17266 | bHLHb20 | transcription factor 12 | HEBa interacts with CBP. This interaction was modeled on a demonstrated interaction between HEBb and CBP. | BIND | 15333839 |
TCF12 | HEB | HTF4 | HsT17266 | bHLHb20 | transcription factor 12 | HEBb interacts with CBP. | BIND | 15333839 |
TCF3 | E2A | ITF1 | MGC129647 | MGC129648 | bHLHb21 | transcription factor 3 (E2A immunoglobulin enhancer binding factors E12/E47) | - | HPRD,BioGRID | 12435739 |
TDG | - | thymine-DNA glycosylase | - | HPRD,BioGRID | 11864601 |
TFF1 | BCEI | D21S21 | HP1.A | HPS2 | pNR-2 | pS2 | trefoil factor 1 | CBP interacts with pS2. | BIND | 10490106 |
TGS1 | DKFZp762A163 | FLJ22995 | NCOA6IP | PIMT | PIPMT | trimethylguanosine synthase homolog (S. cerevisiae) | - | HPRD,BioGRID | 11912212 |
TNFSF10 | APO2L | Apo-2L | CD253 | TL2 | TRAIL | tumor necrosis factor (ligand) superfamily, member 10 | CBP interacts with the TNFSF10 promoter. | BIND | 15619633 |
TP53 | FLJ92943 | LFS1 | TRP53 | p53 | tumor protein p53 | - | HPRD,BioGRID | 10848610 |11782467 |
TP53 | FLJ92943 | LFS1 | TRP53 | p53 | tumor protein p53 | p53 interacts with CBP. This interaction was modeled on a demonstrated interaction between human p53 and CBP from an unspecified species. | BIND | 10823891 |
TRAM2 | KIAA0057 | translocation associated membrane protein 2 | - | HPRD | 14612417 |
TRERF1 | BCAR2 | FLJ21198 | HSA277276 | RAPA | RP1-139D8.5 | TReP-132 | dJ139D8.5 | transcriptional regulating factor 1 | - | HPRD,BioGRID | 11349124 |
TRIP4 | HsT17391 | thyroid hormone receptor interactor 4 | - | HPRD,BioGRID | 10454579 |
XRCC6 | CTC75 | CTCBF | G22P1 | KU70 | ML8 | TLAA | X-ray repair complementing defective repair in Chinese hamster cells 6 | Reconstituted Complex Two-hybrid | BioGRID | 9488450 |
YWHAH | YWHA1 | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta polypeptide | - | HPRD | 11266503 |
Section V. Pathway annotation
Pathway name | Pathway size | # SZGR 2.0 genes in pathway | Info |
---|---|---|---|
KEGG CELL CYCLE | 128 | 84 | All SZGR 2.0 genes in this pathway |
KEGG WNT SIGNALING PATHWAY | 151 | 112 | All SZGR 2.0 genes in this pathway |
KEGG NOTCH SIGNALING PATHWAY | 47 | 35 | All SZGR 2.0 genes in this pathway |
KEGG TGF BETA SIGNALING PATHWAY | 86 | 64 | All SZGR 2.0 genes in this pathway |
KEGG ADHERENS JUNCTION | 75 | 53 | All SZGR 2.0 genes in this pathway |
KEGG JAK STAT SIGNALING PATHWAY | 155 | 105 | All SZGR 2.0 genes in this pathway |
KEGG LONG TERM POTENTIATION | 70 | 57 | All SZGR 2.0 genes in this pathway |
KEGG MELANOGENESIS | 102 | 80 | All SZGR 2.0 genes in this pathway |
KEGG HUNTINGTONS DISEASE | 185 | 109 | All SZGR 2.0 genes in this pathway |
KEGG PATHWAYS IN CANCER | 328 | 259 | All SZGR 2.0 genes in this pathway |
KEGG RENAL CELL CARCINOMA | 70 | 60 | All SZGR 2.0 genes in this pathway |
KEGG PROSTATE CANCER | 89 | 75 | All SZGR 2.0 genes in this pathway |
BIOCARTA RELA PATHWAY | 16 | 12 | All SZGR 2.0 genes in this pathway |
BIOCARTA CSK PATHWAY | 24 | 20 | All SZGR 2.0 genes in this pathway |
BIOCARTA CARM ER PATHWAY | 35 | 27 | All SZGR 2.0 genes in this pathway |
BIOCARTA VDR PATHWAY | 12 | 7 | All SZGR 2.0 genes in this pathway |
BIOCARTA SET PATHWAY | 11 | 6 | All SZGR 2.0 genes in this pathway |
BIOCARTA IL7 PATHWAY | 17 | 14 | All SZGR 2.0 genes in this pathway |
BIOCARTA PPARA PATHWAY | 58 | 43 | All SZGR 2.0 genes in this pathway |
BIOCARTA PITX2 PATHWAY | 15 | 15 | All SZGR 2.0 genes in this pathway |
BIOCARTA NFAT PATHWAY | 56 | 45 | All SZGR 2.0 genes in this pathway |
BIOCARTA NTHI PATHWAY | 24 | 20 | All SZGR 2.0 genes in this pathway |
BIOCARTA PML PATHWAY | 17 | 12 | All SZGR 2.0 genes in this pathway |
BIOCARTA TGFB PATHWAY | 19 | 14 | All SZGR 2.0 genes in this pathway |
BIOCARTA CARM1 PATHWAY | 13 | 11 | All SZGR 2.0 genes in this pathway |
BIOCARTA WNT PATHWAY | 26 | 24 | All SZGR 2.0 genes in this pathway |
ST DIFFERENTIATION PATHWAY IN PC12 CELLS | 45 | 35 | All SZGR 2.0 genes in this pathway |
PID SMAD2 3NUCLEAR PATHWAY | 82 | 63 | All SZGR 2.0 genes in this pathway |
PID HDAC CLASSIII PATHWAY | 25 | 20 | All SZGR 2.0 genes in this pathway |
PID E2F PATHWAY | 74 | 48 | All SZGR 2.0 genes in this pathway |
PID HIF2PATHWAY | 34 | 29 | All SZGR 2.0 genes in this pathway |
PID MYC ACTIV PATHWAY | 79 | 62 | All SZGR 2.0 genes in this pathway |
PID PS1 PATHWAY | 46 | 39 | All SZGR 2.0 genes in this pathway |
PID TCPTP PATHWAY | 43 | 33 | All SZGR 2.0 genes in this pathway |
PID HDAC CLASSI PATHWAY | 66 | 50 | All SZGR 2.0 genes in this pathway |
PID NFAT 3PATHWAY | 54 | 47 | All SZGR 2.0 genes in this pathway |
PID REG GR PATHWAY | 82 | 60 | All SZGR 2.0 genes in this pathway |
PID FOXO PATHWAY | 49 | 43 | All SZGR 2.0 genes in this pathway |
PID AJDISS 2PATHWAY | 48 | 38 | All SZGR 2.0 genes in this pathway |
PID P53 DOWNSTREAM PATHWAY | 137 | 94 | All SZGR 2.0 genes in this pathway |
PID AR TF PATHWAY | 53 | 38 | All SZGR 2.0 genes in this pathway |
PID IFNG PATHWAY | 40 | 34 | All SZGR 2.0 genes in this pathway |
PID FOXM1 PATHWAY | 40 | 30 | All SZGR 2.0 genes in this pathway |
PID CMYB PATHWAY | 84 | 61 | All SZGR 2.0 genes in this pathway |
PID RETINOIC ACID PATHWAY | 30 | 23 | All SZGR 2.0 genes in this pathway |
PID HEDGEHOG GLI PATHWAY | 48 | 35 | All SZGR 2.0 genes in this pathway |
PID KIT PATHWAY | 52 | 40 | All SZGR 2.0 genes in this pathway |
PID HIF1 TFPATHWAY | 66 | 52 | All SZGR 2.0 genes in this pathway |
PID P53 REGULATION PATHWAY | 59 | 50 | All SZGR 2.0 genes in this pathway |
PID RB 1PATHWAY | 65 | 46 | All SZGR 2.0 genes in this pathway |
PID HNF3A PATHWAY | 44 | 29 | All SZGR 2.0 genes in this pathway |
PID HES HEY PATHWAY | 48 | 39 | All SZGR 2.0 genes in this pathway |
PID IL12 STAT4 PATHWAY | 33 | 29 | All SZGR 2.0 genes in this pathway |
REACTOME DEVELOPMENTAL BIOLOGY | 396 | 292 | All SZGR 2.0 genes in this pathway |
REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION | 36 | 27 | All SZGR 2.0 genes in this pathway |
REACTOME PPARA ACTIVATES GENE EXPRESSION | 104 | 72 | All SZGR 2.0 genes in this pathway |
REACTOME PRE NOTCH TRANSCRIPTION AND TRANSLATION | 29 | 17 | All SZGR 2.0 genes in this pathway |
REACTOME RORA ACTIVATES CIRCADIAN EXPRESSION | 24 | 17 | All SZGR 2.0 genes in this pathway |
REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION | 24 | 16 | All SZGR 2.0 genes in this pathway |
REACTOME PRE NOTCH EXPRESSION AND PROCESSING | 44 | 24 | All SZGR 2.0 genes in this pathway |
REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION | 46 | 28 | All SZGR 2.0 genes in this pathway |
REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA | 23 | 16 | All SZGR 2.0 genes in this pathway |
REACTOME SIGNALING BY NOTCH1 | 70 | 46 | All SZGR 2.0 genes in this pathway |
REACTOME REGULATION OF HYPOXIA INDUCIBLE FACTOR HIF BY OXYGEN | 25 | 17 | All SZGR 2.0 genes in this pathway |
REACTOME GENERIC TRANSCRIPTION PATHWAY | 352 | 181 | All SZGR 2.0 genes in this pathway |
REACTOME NOTCH HLH TRANSCRIPTION PATHWAY | 13 | 8 | All SZGR 2.0 genes in this pathway |
REACTOME METABOLISM OF LIPIDS AND LIPOPROTEINS | 478 | 302 | All SZGR 2.0 genes in this pathway |
REACTOME FATTY ACID TRIACYLGLYCEROL AND KETONE BODY METABOLISM | 168 | 115 | All SZGR 2.0 genes in this pathway |
REACTOME TRAF6 MEDIATED IRF7 ACTIVATION | 30 | 26 | All SZGR 2.0 genes in this pathway |
REACTOME CIRCADIAN CLOCK | 53 | 40 | All SZGR 2.0 genes in this pathway |
REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION | 132 | 101 | All SZGR 2.0 genes in this pathway |
REACTOME TRAF3 DEPENDENT IRF ACTIVATION PATHWAY | 14 | 10 | All SZGR 2.0 genes in this pathway |
REACTOME RIG I MDA5 MEDIATED INDUCTION OF IFN ALPHA BETA PATHWAYS | 73 | 57 | All SZGR 2.0 genes in this pathway |
REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION | 72 | 53 | All SZGR 2.0 genes in this pathway |
REACTOME SIGNALING BY NOTCH | 103 | 64 | All SZGR 2.0 genes in this pathway |
REACTOME HEMOSTASIS | 466 | 331 | All SZGR 2.0 genes in this pathway |
REACTOME INNATE IMMUNE SYSTEM | 279 | 178 | All SZGR 2.0 genes in this pathway |
REACTOME IMMUNE SYSTEM | 933 | 616 | All SZGR 2.0 genes in this pathway |
BORCZUK MALIGNANT MESOTHELIOMA UP | 305 | 185 | All SZGR 2.0 genes in this pathway |
GARGALOVIC RESPONSE TO OXIDIZED PHOSPHOLIPIDS BLUE UP | 136 | 80 | All SZGR 2.0 genes in this pathway |
KOKKINAKIS METHIONINE DEPRIVATION 48HR UP | 128 | 95 | All SZGR 2.0 genes in this pathway |
KOKKINAKIS METHIONINE DEPRIVATION 96HR UP | 117 | 84 | All SZGR 2.0 genes in this pathway |
GRAESSMANN APOPTOSIS BY DOXORUBICIN DN | 1781 | 1082 | All SZGR 2.0 genes in this pathway |
SCHLOSSER SERUM RESPONSE DN | 712 | 443 | All SZGR 2.0 genes in this pathway |
SCHEIDEREIT IKK INTERACTING PROTEINS | 58 | 45 | All SZGR 2.0 genes in this pathway |
DACOSTA UV RESPONSE VIA ERCC3 DN | 855 | 609 | All SZGR 2.0 genes in this pathway |
DACOSTA UV RESPONSE VIA ERCC3 COMMON DN | 483 | 336 | All SZGR 2.0 genes in this pathway |
PUJANA BREAST CANCER LIT INT NETWORK | 101 | 73 | All SZGR 2.0 genes in this pathway |
BUYTAERT PHOTODYNAMIC THERAPY STRESS UP | 811 | 508 | All SZGR 2.0 genes in this pathway |
LOPEZ MBD TARGETS | 957 | 597 | All SZGR 2.0 genes in this pathway |
SCHAEFFER PROSTATE DEVELOPMENT 6HR DN | 514 | 330 | All SZGR 2.0 genes in this pathway |
SMITH TERT TARGETS UP | 145 | 91 | All SZGR 2.0 genes in this pathway |
FLECHNER BIOPSY KIDNEY TRANSPLANT OK VS DONOR UP | 555 | 346 | All SZGR 2.0 genes in this pathway |
THEILGAARD NEUTROPHIL AT SKIN WOUND DN | 225 | 163 | All SZGR 2.0 genes in this pathway |
CUI TCF21 TARGETS 2 DN | 830 | 547 | All SZGR 2.0 genes in this pathway |
BLALOCK ALZHEIMERS DISEASE UP | 1691 | 1088 | All SZGR 2.0 genes in this pathway |
DAZARD RESPONSE TO UV NHEK DN | 318 | 220 | All SZGR 2.0 genes in this pathway |
KRASNOSELSKAYA ILF3 TARGETS DN | 46 | 38 | All SZGR 2.0 genes in this pathway |
DURCHDEWALD SKIN CARCINOGENESIS DN | 264 | 168 | All SZGR 2.0 genes in this pathway |
MONNIER POSTRADIATION TUMOR ESCAPE UP | 393 | 244 | All SZGR 2.0 genes in this pathway |
SANSOM APC MYC TARGETS | 217 | 138 | All SZGR 2.0 genes in this pathway |
SANSOM APC TARGETS REQUIRE MYC | 210 | 123 | All SZGR 2.0 genes in this pathway |
KYNG DNA DAMAGE BY GAMMA AND UV RADIATION | 88 | 65 | All SZGR 2.0 genes in this pathway |
KYNG DNA DAMAGE DN | 195 | 135 | All SZGR 2.0 genes in this pathway |
IWANAGA CARCINOGENESIS BY KRAS UP | 170 | 107 | All SZGR 2.0 genes in this pathway |
ACEVEDO LIVER CANCER UP | 973 | 570 | All SZGR 2.0 genes in this pathway |
BONOME OVARIAN CANCER SURVIVAL SUBOPTIMAL DEBULKING | 510 | 309 | All SZGR 2.0 genes in this pathway |
GRADE COLON CANCER UP | 871 | 505 | All SZGR 2.0 genes in this pathway |
GRESHOCK CANCER COPY NUMBER UP | 323 | 240 | All SZGR 2.0 genes in this pathway |
ROME INSULIN TARGETS IN MUSCLE DN | 204 | 114 | All SZGR 2.0 genes in this pathway |
PLASARI TGFB1 SIGNALING VIA NFIC 1HR DN | 106 | 77 | All SZGR 2.0 genes in this pathway |
Section VI. microRNA annotation
miRNA family | Target position | miRNA ID | miRNA seq | ||
---|---|---|---|---|---|
UTR start | UTR end | Match method | |||
miR-137 | 759 | 765 | m8 | hsa-miR-137 | UAUUGCUUAAGAAUACGCGUAG |
miR-153 | 996 | 1002 | m8 | hsa-miR-153 | UUGCAUAGUCACAAAAGUGA |
miR-186 | 1079 | 1085 | 1A | hsa-miR-186 | CAAAGAAUUCUCCUUUUGGGCUU |
miR-200bc/429 | 518 | 525 | 1A,m8 | hsa-miR-200b | UAAUACUGCCUGGUAAUGAUGAC |
hsa-miR-200c | UAAUACUGCCGGGUAAUGAUGG | ||||
hsa-miR-429 | UAAUACUGUCUGGUAAAACCGU | ||||
miR-23 | 737 | 743 | 1A | hsa-miR-23abrain | AUCACAUUGCCAGGGAUUUCC |
hsa-miR-23bbrain | AUCACAUUGCCAGGGAUUACC | ||||
miR-26 | 744 | 750 | 1A | hsa-miR-26abrain | UUCAAGUAAUCCAGGAUAGGC |
hsa-miR-26bSZ | UUCAAGUAAUUCAGGAUAGGUU | ||||
hsa-miR-26abrain | UUCAAGUAAUCCAGGAUAGGC | ||||
hsa-miR-26bSZ | UUCAAGUAAUUCAGGAUAGGUU | ||||
miR-30-3p | 49 | 56 | 1A,m8 | hsa-miR-30a-3p | CUUUCAGUCGGAUGUUUGCAGC |
hsa-miR-30e-3p | CUUUCAGUCGGAUGUUUACAGC | ||||
miR-330 | 634 | 640 | m8 | hsa-miR-330brain | GCAAAGCACACGGCCUGCAGAGA |
miR-361 | 645 | 652 | 1A,m8 | hsa-miR-361brain | UUAUCAGAAUCUCCAGGGGUAC |
miR-376c | 734 | 740 | m8 | hsa-miR-376c | AACAUAGAGGAAAUUCCACG |
miR-381 | 1018 | 1024 | 1A | hsa-miR-381 | UAUACAAGGGCAAGCUCUCUGU |
miR-410 | 1121 | 1127 | 1A | hsa-miR-410 | AAUAUAACACAGAUGGCCUGU |
miR-488 | 183 | 189 | m8 | hsa-miR-488 | CCCAGAUAAUGGCACUCUCAA |
miR-493-5p | 923 | 929 | m8 | hsa-miR-493-5p | UUGUACAUGGUAGGCUUUCAUU |
miR-495 | 158 | 164 | 1A | hsa-miR-495brain | AAACAAACAUGGUGCACUUCUUU |
hsa-miR-495brain | AAACAAACAUGGUGCACUUCUUU | ||||
miR-543 | 1098 | 1104 | m8 | hsa-miR-543 | AAACAUUCGCGGUGCACUUCU |
hsa-miR-543 | AAACAUUCGCGGUGCACUUCU |
- SZ: miRNAs which differentially expressed in brain cortex of schizophrenia patients comparing with control samples using microarray. Click here to see the list of SZ related miRNAs.
- Brain: miRNAs which are expressed in brain based on miRNA microarray expression studies. Click here to see the list of brain related miRNAs.