Gene Page: TRPC4AP
Summary ?
| GeneID | 26133 |
| Symbol | TRPC4AP |
| Synonyms | C20orf188|PPP1R158|TRRP4AP|TRUSS |
| Description | transient receptor potential cation channel subfamily C member 4 associated protein |
| Reference | MIM:608430|HGNC:HGNC:16181|Ensembl:ENSG00000100991|HPRD:09238|Vega:OTTHUMG00000032319 |
| Gene type | protein-coding |
| Map location | 20q11.22 |
| Pascal p-value | 0.09 |
| Sherlock p-value | 0.008 |
| eGene | Putamen basal ganglia Myers' cis & trans Meta |
| Support | CompositeSet Darnell FMRP targets Ascano FMRP targets |
Gene in Data Sources
| Gene set name | Method of gene set | Description | Info |
|---|---|---|---|
| CV:PGCnp | Genome-wide Association Study | GWAS |
Section I. Genetics and epigenetics annotation
eQTL annotation
| SNP ID | Chromosome | Position | eGene | Gene Entrez ID | pvalue | qvalue | TSS distance | eQTL type |
|---|---|---|---|---|---|---|---|---|
| rs6088662 | chr20 | 33547632 | TRPC4AP | 26133 | 0 | cis | ||
| rs6088667 | chr20 | 33566721 | TRPC4AP | 26133 | 0 | cis | ||
| rs3818253 | chr20 | 33596875 | TRPC4AP | 26133 | 0.01 | cis | ||
| rs6088678 | chr20 | 33607550 | TRPC4AP | 26133 | 0.01 | cis | ||
| rs6120804 | chr20 | 33623700 | TRPC4AP | 26133 | 0.01 | cis | ||
| rs6120828 | chr20 | 33674459 | TRPC4AP | 26133 | 0 | cis | ||
| rs3746429 | chr20 | 33703606 | TRPC4AP | 26133 | 0.01 | cis | ||
| rs6120849 | chr20 | 33730386 | TRPC4AP | 26133 | 0 | cis | ||
| rs6088738 | chr20 | 33747330 | TRPC4AP | 26133 | 0.04 | cis | ||
| rs2425024 | chr20 | 33844937 | TRPC4AP | 26133 | 0.13 | cis | ||
| rs6088662 | chr20 | 33547632 | TRPC4AP | 26133 | 0.2 | trans | ||
| rs6088667 | chr20 | 33566721 | TRPC4AP | 26133 | 0.09 | trans | ||
| rs6120828 | chr20 | 33674459 | TRPC4AP | 26133 | 0.14 | trans | ||
| rs6120849 | chr20 | 33730386 | TRPC4AP | 26133 | 0.16 | trans | ||
| rs4396783 | 20 | 33741052 | TRPC4AP | ENSG00000100991.7 | 4.648E-6 | 0.03 | -60378 | gtex_brain_putamen_basal |
Section II. Transcriptome annotation
General gene expression (GTEx)
Gene expression of temporal and spatial changes (BrainSpan)
Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes the lower 25% and upper 25% of the expression distribution.
No co-expressed genes in brain regions
Section V. Pathway annotation
| Pathway name | Pathway size | # SZGR 2.0 genes in pathway | Info |
|---|---|---|---|
| SCHEIDEREIT IKK INTERACTING PROTEINS | 58 | 45 | All SZGR 2.0 genes in this pathway |
| MARTORIATI MDM4 TARGETS FETAL LIVER DN | 514 | 319 | All SZGR 2.0 genes in this pathway |
| NUYTTEN NIPP1 TARGETS DN | 848 | 527 | All SZGR 2.0 genes in this pathway |
| BENPORATH NANOG TARGETS | 988 | 594 | All SZGR 2.0 genes in this pathway |
| BENPORATH SOX2 TARGETS | 734 | 436 | All SZGR 2.0 genes in this pathway |
| NIKOLSKY BREAST CANCER 20Q11 AMPLICON | 31 | 18 | All SZGR 2.0 genes in this pathway |
| MARSON BOUND BY FOXP3 STIMULATED | 1022 | 619 | All SZGR 2.0 genes in this pathway |
| MARSON BOUND BY FOXP3 UNSTIMULATED | 1229 | 713 | All SZGR 2.0 genes in this pathway |
| ZHANG BREAST CANCER PROGENITORS DN | 145 | 93 | All SZGR 2.0 genes in this pathway |
| QI HYPOXIA TARGETS OF HIF1A AND FOXA2 | 37 | 27 | All SZGR 2.0 genes in this pathway |
| FIGUEROA AML METHYLATION CLUSTER 5 DN | 50 | 31 | All SZGR 2.0 genes in this pathway |
| TERAO AOX4 TARGETS SKIN UP | 38 | 27 | All SZGR 2.0 genes in this pathway |