Search results: The pahtway p40 has 54 genes in the original annotation. Currently, there are 42 genes in SZGR 2.0 (with evidence in schizophrenia) that are present at this pathway.

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Gene ID Symbol Synonyms Official Full Name Location SZ group ? Functional group ?
5305PIP4K2API5P4KA | PIP5K2A | PIP5KII-alpha | PIP5KIIA | PIPKphosphatidylinositol-5-phosphate 4-kinase, type II, alpha10p12.2Association
CV:PGCnp
DEG:Zhao_2015
DMG:Wockner_2014
GR_COR
GR_Ng
GR_WM
PMID:cooccur
G2Cdb.human_BAYES-COLLINS-HUMAN-PSD-CONSENSUS
G2Cdb.human_BAYES-COLLINS-HUMAN-PSD-FULL
G2Cdb.human_BAYES-COLLINS-MOUSE-PSD-CONSENSUS
G2Cdb.humanPSD
G2Cdb.humanPSP
CompositeSet
9562MINPP1HIPER1 | MINPP2 | MIPPmultiple inositol-polyphosphate phosphatase 110q23CV:GWASdb
CV:PGCnp
5728PTEN10q23del | BZS | CWS1 | DEC | GLM2 | MHAM | MMAC1 | PTEN1 | TEP1phosphatase and tensin homolog10q23.3CV:PGCnp
DMG:Wockner_2014
GO_Annotation
Network
PMID:cooccur
CompositeSet
Darnell FMRP targets
3632INPP5A5PTASEinositol polyphosphate-5-phosphatase A10q26.3CV:PGCnp
DMG:Wockner_2014
DNM:Xu_2012
GSMA_IIA
CompositeSet
5286PIK3C2ACPK | PI3-K-C2(ALPHA) | PI3-K-C2Aphosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 alpha11p15.5-p14CV:GWAScat
CV:GWASdb
CV:PGCnp
PMID:cooccur
5331PLCB3-phospholipase C beta 311q13CV:PGCnp
DMG:Wockner_2014
CANABINOID
INTRACELLULAR SIGNAL TRANSDUCTION
METABOTROPIC GLUTAMATE RECEPTOR
SEROTONIN
5288PIK3C2GPI3K-C2-gamma | PI3K-C2GAMMAphosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 gamma12p12Association
CV:GWAScat
CV:GWASdb
CV:PGCnp
PMID:cooccur
7167TPI1HEL-S-49 | TIM | TPI | TPIDtriosephosphate isomerase 112p13Expression
PMID:cooccur
G2Cdb.humanNRC
G2Cdb.humanPSD
G2Cdb.humanPSP
CompositeSet
3705ITPK1ITRPK1inositol-tetrakisphosphate 1-kinase14q31CV:PGCnp
DMG:Wockner_2014
5330PLCB2PLC-beta-2phospholipase C beta 215q15CV:GWAScat
CV:GWASdb
CV:PGCnp
PMID:cooccur
10423CDIPTPIS | PIS1CDP-diacylglycerol--inositol 3-phosphatidyltransferase16p11.2CNV:YES
CV:PGCnp
GSMA_IIE
G2Cdb.humanPSD
G2Cdb.humanPSP
5336PLCG2APLAID | FCAS3 | PLC-IV | PLC-gamma-2phospholipase C gamma 216q24.1CV:GWASdb
CV:PGCnp
PMID:cooccur
51763INPP5KPPS | SKIPinositol polyphosphate-5-phosphatase K17p13.3CV:PGCnp
GO_Annotation
8396PIP4K2BPI5P4KB | PIP5K2B | PIP5KIIB | PIP5KIIbeta | PIP5P4KBphosphatidylinositol-5-phosphate 4-kinase, type II, beta17q12CV:PGCnp
DMG:Jaffe_2016
CELL METABOLISM
G2Cdb.human_BAYES-COLLINS-HUMAN-PSD-CONSENSUS
G2Cdb.human_BAYES-COLLINS-HUMAN-PSD-FULL
G2Cdb.humanPSD
G2Cdb.humanPSP
CompositeSet
113026PLCD3PLC-delta-3phospholipase C delta 317q21.31CV:PGCnpG2Cdb.human_BAYES-COLLINS-HUMAN-PSD-FULL
3613IMPA2-inositol(myo)-1(or 4)-monophosphatase 218p11.2Association
CV:PGCnp
CV:PheWAS
PMID:cooccur
5289PIK3C3VPS34 | Vps34 | hVps34phosphatidylinositol 3-kinase catalytic subunit type 318q12.3Association
CV:PGCnp
GR_WM
PMID:cooccur
51477ISYNA1INO1 | INOS | IPS | IPS 1 | IPS-1inositol-3-phosphate synthase 119p13.11CV:PGCnp
3633INPP5B5PTaseinositol polyphosphate-5-phosphatase B1p34CV:PGCnp
5293PIK3CDAPDS | IMD14 | P110DELTA | PI3K | p110Dphosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta1p36.2CV:PGCnp
DMG:Wockner_2014
PMID:cooccur
5298PI4KBNPIK | PI4K-BETA | PI4K92 | PI4KBETA | PI4KIIIBETA | PIK4CBphosphatidylinositol 4-kinase beta1q21CV:PGCnp
DEG:Maycox_2009
DMG:Jaffe_2016
GSMA_I
GSMA_IIA
8394PIP5K1A-phosphatidylinositol-4-phosphate 5-kinase, type I, alpha1q21.3CV:PGCnp
DMG:Nishioka_2013
DMG:Wockner_2014
GSMA_I
GSMA_IIA
5287PIK3C2BC2-PI3Kphosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 beta1q32CV:PGCnp
DNM:Fromer_2014
CompositeSet
3707ITPKBIP3-3KB | IP3K | IP3K-B | IP3KB | PIG37inositol-trisphosphate 3-kinase B1q42.13CV:PGCnp
DMG:Wockner_2014
Network
23236PLCB1EIEE12 | PI-PLC | PLC-154 | PLC-I | PLC-beta-1 | PLC154 | PLCB1A | PLCB1Bphospholipase C beta 120p12CV:PGCnp
CV:PheWAS
DMG:Jaffe_2016
DMG:Nishioka_2013
GSMA_I
Network
PMID:cooccur
CANABINOID
INTRACELLULAR SIGNAL TRANSDUCTION
METABOTROPIC GLUTAMATE RECEPTOR
SEROTONIN
G2Cdb.human_BAYES-COLLINS-HUMAN-PSD-CONSENSUS
G2Cdb.human_BAYES-COLLINS-HUMAN-PSD-FULL
G2Cdb.human_BAYES-COLLINS-MOUSE-PSD-CONSENSUS
G2Cdb.human_mGluR5
G2Cdb.humanNRC
G2Cdb.humanPSD
G2Cdb.humanPSP
CompositeSet
Darnell FMRP targets
Ascano FMRP targets
Potential synaptic genes
5332PLCB4ARCND2 | PI-PLCphospholipase C beta 420p12CV:PGCnp
GO_Annotation
GSMA_I
PMID:cooccur
CANABINOID
INTRACELLULAR SIGNAL TRANSDUCTION
METABOTROPIC GLUTAMATE RECEPTOR
SEROTONIN
5335PLCG1NCKAP3 | PLC-II | PLC1 | PLC148 | PLCgamma1phospholipase C gamma 120q12-q13.1CV:PGCnp
Network
INTRACELLULAR SIGNAL TRANSDUCTION
G2Cdb.humanNRC
G2Cdb.humanPSP
Ascano FMRP targets
Potential synaptic genes
8867SYNJ1INPP5G | PARK20synaptojanin 121q22.2CV:PGCnp
GO_Annotation
Network
PMID:cooccur
ENDOCYTOSIS
G2Cdb.human_BAYES-COLLINS-HUMAN-PSD-CONSENSUS
G2Cdb.human_BAYES-COLLINS-HUMAN-PSD-FULL
G2Cdb.human_BAYES-COLLINS-MOUSE-PSD-CONSENSUS
G2Cdb.human_clathrin
G2Cdb.human_mGluR5
G2Cdb.human_Synaptosome
CompositeSet
Darnell FMRP targets
Potential synaptic genes
5297PI4KAPI4K-ALPHA | PIK4CA | PMGYCHA | pi4K230phosphatidylinositol 4-kinase alpha22q11.21Association
CNV:YES
CV:PGCnp
GO_Annotation
GSMA_I
PMID:cooccur
CELL METABOLISM
G2Cdb.humanPSD
G2Cdb.humanPSP
CompositeSet
Darnell FMRP targets
Ascano FMRP targets
27124INPP5JINPP5 | PIB5PA | PIPPinositol polyphosphate-5-phosphatase J22q12.2CV:GWASdb
CV:PGCnp
PMID:cooccur
55586MIOXALDRL6myo-inositol oxygenase22q13.3CV:PGCnp
Expression
3631INPP4AINPP4 | TVAS1inositol polyphosphate-4-phosphatase type I A2q11.2CV:GWASdb
CV:PGCnp
DMG:Wockner_2014
GSMA_I
INTRACELLULAR SIGNAL TRANSDUCTION
G2Cdb.humanPSD
G2Cdb.humanPSP
CompositeSet
Darnell FMRP targets
84812PLCD4-phospholipase C delta 42q35CV:PGCnp
DNM:McCarthy_2014
GSMA_IIA
GSMA_IIE
5333PLCD1NDNC3 | PLC-IIIphospholipase C delta 13p22-p21.3CV:PGCnp
DMG:Wockner_2014
GSMA_I
G2Cdb.human_BAYES-COLLINS-HUMAN-PSD-FULL
5291PIK3CBP110BETA | PI3K | PI3KBETA | PIK3C1phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta3q22.3CV:PGCnp
DNM:Girard_2011
Network
CompositeSet
5290PIK3CACLOVE | CWS5 | MCAP | MCM | MCMTC | PI3K | p110-alphaphosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha3q26.3CV:PGCnp
Network
PMID:cooccur
G2Cdb.humanNRC
G2Cdb.humanPSD
G2Cdb.humanPSP
Potential synaptic genes
8821INPP4B-inositol polyphosphate-4-phosphatase type II B4q31.21CV:PGCnp
DMG:Jaffe_2016
DMG:Wockner_2014
8871SYNJ2INPP5Hsynaptojanin 26q25.3CV:PGCnp
DMG:Montano_2016
DMG:Wockner_2014
ENDOCYTOSIS
G2Cdb.humanPSD
G2Cdb.humanPSP
3612IMPA1IMP | IMPAinositol(myo)-1(or 4)-monophosphatase 18q21.13-q21.3CV:PGCnp
PMID:cooccur
G2Cdb.human_BAYES-COLLINS-HUMAN-PSD-FULL
G2Cdb.humanPSD
G2Cdb.humanPSP
8395PIP5K1BMSS4 | STM7phosphatidylinositol-4-phosphate 5-kinase, type I, beta9q13CV:PGCnp
DMG:Jaffe_2016
DMG:Wockner_2014
PMID:cooccur
64768IPPKC9orf12 | INSP5K2 | IP5K | IPK1 | bA476B13.1inositol-pentakisphosphate 2-kinase9q22.31CV:GWASdb
CV:PGCnp
56623INPP5ECORS1 | CPD4 | JBTS1 | MORMS | PPI5PIVinositol polyphosphate-5-phosphatase E9q34.3CV:PGCnp
DMG:Jaffe_2016