Gene Page: TEX14
Summary ?
| GeneID | 56155 |
| Symbol | TEX14 |
| Synonyms | CT113 |
| Description | testis expressed 14 |
| Reference | MIM:605792|HGNC:HGNC:11737|Ensembl:ENSG00000121101|Vega:OTTHUMG00000179245 |
| Gene type | protein-coding |
| Map location | 17q22 |
| Pascal p-value | 0.001 |
| eGene | Caudate basal ganglia Nucleus accumbens basal ganglia |
Gene in Data Sources
| Gene set name | Method of gene set | Description | Info |
|---|---|---|---|
| CV:PGCnp | Genome-wide Association Study | GWAS | |
| DMG:Wockner_2014 | Genome-wide DNA methylation analysis | This dataset includes 4641 differentially methylated probes corresponding to 2929 unique genes between schizophrenia patients (n=24) and controls (n=24). | 1 |
Section I. Genetics and epigenetics annotation
Differentially methylated gene
| Probe | Chromosome | Position | Nearest gene | P (dis) | Beta (dis) | FDR (dis) | Study |
|---|---|---|---|---|---|---|---|
| cg19532212 | 17 | 56769430 | TEX14;RAD51C | 5.264E-4 | 0.392 | 0.048 | DMG:Wockner_2014 |
Section II. Transcriptome annotation
General gene expression (GTEx)
Gene expression of temporal and spatial changes (BrainSpan)
Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes the lower 25% and upper 25% of the expression distribution.
Top co-expressed genes in brain regions
| Top 10 positively co-expressed genes | ||
| Gene | Pearson's Correlation | Spearman's Correlation |
| MAPK7 | 0.96 | 0.96 |
| NUP62 | 0.95 | 0.93 |
| PATZ1 | 0.95 | 0.93 |
| ZNF74 | 0.95 | 0.94 |
| EPHB2 | 0.95 | 0.93 |
| ZBTB12 | 0.95 | 0.94 |
| RBM15B | 0.95 | 0.94 |
| PLXNB2 | 0.95 | 0.94 |
| NUP188 | 0.95 | 0.93 |
| EHMT1 | 0.94 | 0.94 |
| Top 10 negatively co-expressed genes | ||
| Gene | Pearson's Correlation | Spearman's Correlation |
| C5orf53 | -0.71 | -0.80 |
| HLA-F | -0.69 | -0.72 |
| FBXO2 | -0.67 | -0.62 |
| AIFM3 | -0.67 | -0.68 |
| AF347015.27 | -0.67 | -0.88 |
| S100B | -0.66 | -0.81 |
| ALDOC | -0.66 | -0.64 |
| AF347015.31 | -0.66 | -0.87 |
| PTH1R | -0.66 | -0.64 |
| CA4 | -0.65 | -0.70 |
Section V. Pathway annotation
| Pathway name | Pathway size | # SZGR 2.0 genes in pathway | Info |
|---|---|---|---|
| DAVICIONI MOLECULAR ARMS VS ERMS UP | 332 | 228 | All SZGR 2.0 genes in this pathway |
| GAL LEUKEMIC STEM CELL DN | 244 | 153 | All SZGR 2.0 genes in this pathway |
| NIKOLSKY BREAST CANCER 17Q21 Q25 AMPLICON | 335 | 181 | All SZGR 2.0 genes in this pathway |
| MATZUK SPERMATOCYTE | 72 | 55 | All SZGR 2.0 genes in this pathway |
| BOQUEST STEM CELL DN | 216 | 143 | All SZGR 2.0 genes in this pathway |
| BRUINS UVC RESPONSE VIA TP53 GROUP A | 898 | 516 | All SZGR 2.0 genes in this pathway |
| DALESSIO TSA RESPONSE | 29 | 16 | All SZGR 2.0 genes in this pathway |