Gene Page: RPRD1B
Summary ?
GeneID | 58490 |
Symbol | RPRD1B |
Synonyms | C20orf77|CREPT|NET60|dJ1057B20.2 |
Description | regulation of nuclear pre-mRNA domain containing 1B |
Reference | MIM:614694|HGNC:HGNC:16209|Ensembl:ENSG00000101413|HPRD:08513|Vega:OTTHUMG00000032434 |
Gene type | protein-coding |
Map location | 20q11.23 |
Pascal p-value | 0.092 |
Fetal beta | 0.593 |
eGene | Cerebellar Hemisphere Cerebellum Myers' cis & trans |
Gene in Data Sources
Gene set name | Method of gene set | Description | Info |
---|---|---|---|
CV:GWASdb | Genome-wide Association Studies | GWASdb records for schizophrenia | |
CV:PGCnp | Genome-wide Association Study | GWAS |
Section I. Genetics and epigenetics annotation
eQTL annotation
SNP ID | Chromosome | Position | eGene | Gene Entrez ID | pvalue | qvalue | TSS distance | eQTL type |
---|---|---|---|---|---|---|---|---|
rs7132043 | chr12 | 80968399 | RPRD1B | 58490 | 0.13 | trans |
Section II. Transcriptome annotation
General gene expression (GTEx)

Gene expression during devlopment (BrainCloud)
Footnote:
A total of 269 time points ploted, with n=38 fetal samples (x=1:38). Each triangle represents one time point.
Gene expression of temporal and spatial changes (BrainSpan)
Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes the lower 25% and upper 25% of the expression distribution.
Top co-expressed genes in brain regions
Top 10 positively co-expressed genes | ||
Gene | Pearson's Correlation | Spearman's Correlation |
SLC30A9 | 0.91 | 0.88 |
PPP2CA | 0.90 | 0.87 |
PPME1 | 0.90 | 0.88 |
STAU2 | 0.90 | 0.87 |
KLRAQ1 | 0.89 | 0.88 |
FAM49B | 0.89 | 0.86 |
RAB2A | 0.89 | 0.86 |
DNAJA2 | 0.89 | 0.85 |
MORF4L2 | 0.89 | 0.85 |
RHOT1 | 0.88 | 0.86 |
Top 10 negatively co-expressed genes | ||
Gene | Pearson's Correlation | Spearman's Correlation |
AF347015.26 | -0.70 | -0.60 |
MT-CO2 | -0.69 | -0.59 |
AF347015.2 | -0.68 | -0.56 |
AF347015.8 | -0.67 | -0.58 |
AF347015.33 | -0.67 | -0.58 |
AF347015.21 | -0.66 | -0.55 |
MT-CYB | -0.66 | -0.57 |
HIGD1B | -0.66 | -0.59 |
FXYD1 | -0.66 | -0.62 |
AF347015.31 | -0.66 | -0.57 |
Section V. Pathway annotation
Pathway name | Pathway size | # SZGR 2.0 genes in pathway | Info |
---|---|---|---|
BERENJENO TRANSFORMED BY RHOA UP | 536 | 340 | All SZGR 2.0 genes in this pathway |
KONG E2F3 TARGETS | 97 | 58 | All SZGR 2.0 genes in this pathway |
DOUGLAS BMI1 TARGETS DN | 314 | 188 | All SZGR 2.0 genes in this pathway |
MARSON BOUND BY E2F4 UNSTIMULATED | 728 | 415 | All SZGR 2.0 genes in this pathway |