Summary ?
GeneID58490
SymbolRPRD1B
SynonymsC20orf77|CREPT|NET60|dJ1057B20.2
Descriptionregulation of nuclear pre-mRNA domain containing 1B
ReferenceMIM:614694|HGNC:HGNC:16209|Ensembl:ENSG00000101413|HPRD:08513|Vega:OTTHUMG00000032434
Gene typeprotein-coding
Map location20q11.23
Pascal p-value0.092
Fetal beta0.593
eGeneCerebellar Hemisphere
Cerebellum
Myers' cis & trans

Gene in Data Sources
Gene set name Method of gene setDescriptionInfo
CV:GWASdbGenome-wide Association StudiesGWASdb records for schizophrenia
CV:PGCnpGenome-wide Association StudyGWAS

Section I. Genetics and epigenetics annotation

@eQTL annotation

SNP IDChromosomePositioneGeneGene Entrez IDpvalueqvalueTSS distanceeQTL type
rs7132043chr1280968399RPRD1B584900.13trans

Section II. Transcriptome annotation

General gene expression (GTEx)

Not available

Gene expression during devlopment (BrainCloud)

Footnote:
A total of 269 time points ploted, with n=38 fetal samples (x=1:38). Each triangle represents one time point.

Gene expression of temporal and spatial changes (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes the lower 25% and upper 25% of the expression distribution.

Top co-expressed genes in brain regions

Top 10 positively co-expressed genes
GenePearson's Correlation Spearman's Correlation
SLC30A90.910.88
PPP2CA0.900.87
PPME10.900.88
STAU20.900.87
KLRAQ10.890.88
FAM49B0.890.86
RAB2A0.890.86
DNAJA20.890.85
MORF4L20.890.85
RHOT10.880.86
Top 10 negatively co-expressed genes
GenePearson's Correlation Spearman's Correlation
AF347015.26-0.70-0.60
MT-CO2-0.69-0.59
AF347015.2-0.68-0.56
AF347015.8-0.67-0.58
AF347015.33-0.67-0.58
AF347015.21-0.66-0.55
MT-CYB-0.66-0.57
HIGD1B-0.66-0.59
FXYD1-0.66-0.62
AF347015.31-0.66-0.57

Section V. Pathway annotation

Pathway namePathway size# SZGR 2.0 genes in pathwayInfo
BERENJENO TRANSFORMED BY RHOA UP 536340All SZGR 2.0 genes in this pathway
KONG E2F3 TARGETS 9758All SZGR 2.0 genes in this pathway
DOUGLAS BMI1 TARGETS DN 314188All SZGR 2.0 genes in this pathway
MARSON BOUND BY E2F4 UNSTIMULATED 728415All SZGR 2.0 genes in this pathway