Gene Page: JAM2

Summary
GeneID  58494
Symbol  JAM2
Synonyms  C21orf43|CD322|JAM-B|JAMB|PRO245|VE-JAM|VEJAM
Description  junctional adhesion molecule 2
See related  HGNC:14686|MIM:606870|Ensembl:ENSG00000154721|HPRD:06041|
Locus tag  -
Gene type  protein-coding
Map location  21q21.2
 
Gene in Data Sources
Gene set name Method of gene set Evidence Info
GO_AnnotationMapping neuro-related keywords to Gene Ontology annotationsHits with neuro-related keywords: 1 
 
General Gene Expression (microarray) ?
 
Gene Expression in Brain Regions (new)
 
Top co-expressed genes in Brain Regions (new)
GenePearson's Correlation Spearman's Correlation
Top 10 positively co-expressed genes
NDUFB50.860.79
C2orf640.860.75
NDUFA40.850.75
SDHB0.840.78
NDUFA90.840.75
COX4I10.840.76
AC025647.10.840.74
MRPS330.840.72
GSTO10.820.68
APOA1BP0.820.73
Top 10 negatively co-expressed genes
DMPK-0.43-0.50
AC005921.3-0.43-0.59
SMTN-0.42-0.55
IL3RA-0.42-0.60
AC010300.1-0.41-0.52
TNKS1BP1-0.41-0.38
BAT2D1-0.40-0.33
PRX-0.40-0.45
UPF3A-0.40-0.48
HDAC7-0.40-0.50
Gene Ontology
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0016337cell-cell adhesionNAS10779521 
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0005923tight junctionIEABrain (GO term level: 10)-
GO:0005886plasma membraneEXP17525755 
GO:0005886plasma membraneIEA-
GO:0005887integral to plasma membraneNAS10779521 
GO:0030054cell junctionIEA-
 
InteractionsShown by Network
InteractorsAliases BOfficial full name BExperimentalSourcePubMed ID
F2RL2PAR3coagulation factor II (thrombin) receptor-like 2-HPRD12953056 
JAM3FLJ14529 | JAM-C | JAMCjunctional adhesion molecule 3-HPRD11823489 
PARD3ASIP | Baz | Bazooka | FLJ21015 | PAR3 | PAR3alpha | PARD3A | SE2-5L16 | SE2-5LT1 | SE2-5T2par-3 partitioning defective 3 homolog (C. elegans)Affinity Capture-Western
Reconstituted Complex		BioGRID12953056 
TJP1DKFZp686M05161 | MGC133289 | ZO-1tight junction protein 1 (zona occludens 1)-HPRD,BioGRID12953056 
 
Pathway annotation
Pathway namePathway size# SZGR genes in pathwayInfo
KEGG_CELL_ADHESION_MOLECULES_CAMS 13493All SZGR genes in this pathway
KEGG_TIGHT_JUNCTION 13486All SZGR genes in this pathway
KEGG_LEUKOCYTE_TRANSENDOTHELIAL_MIGRATION 11878All SZGR genes in this pathway
KEGG_EPITHELIAL_CELL_SIGNALING_IN_HELICOBACTER_PYLORI_INFECTION 6844All SZGR genes in this pathway
PID_INTEGRIN1_PATHWAY 6644All SZGR genes in this pathway
PID_AMB2_NEUTROPHILS_PATHWAY 4132All SZGR genes in this pathway
PID_INTEGRIN_A4B1_PATHWAY 3324All SZGR genes in this pathway
REACTOME_CELL_SURFACE_INTERACTIONS_AT_THE_VASCULAR_WALL 9165All SZGR genes in this pathway
REACTOME_INTEGRIN_CELL_SURFACE_INTERACTIONS 7948All SZGR genes in this pathway
REACTOME_HEMOSTASIS 466331All SZGR genes in this pathway
DIAZ_CHRONIC_MEYLOGENOUS_LEUKEMIA_DN 11679All SZGR genes in this pathway
VECCHI_GASTRIC_CANCER_EARLY_DN 367220All SZGR genes in this pathway
SABATES_COLORECTAL_ADENOMA_DN 291176All SZGR genes in this pathway
HAHTOLA_MYCOSIS_FUNGOIDES_SKIN_UP 177113All SZGR genes in this pathway
GAUSSMANN_MLL_AF4_FUSION_TARGETS_A_UP 191128All SZGR genes in this pathway
MARTORIATI_MDM4_TARGETS_NEUROEPITHELIUM_DN 164111All SZGR genes in this pathway
CERVERA_SDHB_TARGETS_1_UP 11866All SZGR genes in this pathway
IVANOVA_HEMATOPOIESIS_STEM_CELL_LONG_TERM 302191All SZGR genes in this pathway
CHEN_LVAD_SUPPORT_OF_FAILING_HEART_DN 4232All SZGR genes in this pathway
CUI_TCF21_TARGETS_2_DN 830547All SZGR genes in this pathway
CLASPER_LYMPHATIC_VESSELS_DURING_METASTASIS_DN 3623All SZGR genes in this pathway
BONOME_OVARIAN_CANCER_SURVIVAL_SUBOPTIMAL_DEBULKING 510309All SZGR genes in this pathway
IZADPANAH_STEM_CELL_ADIPOSE_VS_BONE_DN 10868All SZGR genes in this pathway
BOQUEST_STEM_CELL_DN 216143All SZGR genes in this pathway
CHICAS_RB1_TARGETS_SENESCENT 572352All SZGR genes in this pathway
CHICAS_RB1_TARGETS_GROWING 243155All SZGR genes in this pathway
PASINI_SUZ12_TARGETS_UP 11265All SZGR genes in this pathway
LEE_BMP2_TARGETS_UP 745475All SZGR genes in this pathway
GOBERT_OLIGODENDROCYTE_DIFFERENTIATION_DN 1080713All SZGR genes in this pathway
YANG_BCL3_TARGETS_UP 364236All SZGR genes in this pathway
WANG_MLL_TARGETS 289188All SZGR genes in this pathway
DELACROIX_RAR_BOUND_ES 462273All SZGR genes in this pathway
RAO_BOUND_BY_SALL4 227149All SZGR genes in this pathway
LIM_MAMMARY_STEM_CELL_UP 489314All SZGR genes in this pathway
DURAND_STROMA_NS_UP 162103All SZGR genes in this pathway
ZWANG_CLASS_2_TRANSIENTLY_INDUCED_BY_EGF 5129All SZGR genes in this pathway


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