Gene Page: CCDC90B
Summary ?
| GeneID | 60492 |
| Symbol | CCDC90B |
| Synonyms | MDS011|MDS025 |
| Description | coiled-coil domain containing 90B |
| Reference | HGNC:HGNC:28108|Ensembl:ENSG00000137500|HPRD:14378|Vega:OTTHUMG00000167078 |
| Gene type | protein-coding |
| Map location | 11q14.1 |
| Pascal p-value | 1.297E-4 |
| Sherlock p-value | 0.651 |
| eGene | Caudate basal ganglia Cerebellar Hemisphere Cerebellum Nucleus accumbens basal ganglia Myers' cis & trans |
Gene in Data Sources
| Gene set name | Method of gene set | Description | Info |
|---|---|---|---|
| CV:PGCnp | Genome-wide Association Study | GWAS |
Section I. Genetics and epigenetics annotation
eQTL annotation
| SNP ID | Chromosome | Position | eGene | Gene Entrez ID | pvalue | qvalue | TSS distance | eQTL type |
|---|---|---|---|---|---|---|---|---|
| rs758989 | chr7 | 44203005 | CCDC90B | 60492 | 0.15 | trans |
Section II. Transcriptome annotation
General gene expression (GTEx)
Gene expression of temporal and spatial changes (BrainSpan)
Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes the lower 25% and upper 25% of the expression distribution.
No co-expressed genes in brain regions
Section IV. Protein-protein interaction annotation
| Interactors | Aliases B | Official full name B | Experimental | Source | PubMed ID |
|---|---|---|---|---|---|
| AGR2 | AG2 | GOB-4 | HAG-2 | XAG-2 | anterior gradient homolog 2 (Xenopus laevis) | Two-hybrid | BioGRID | 16169070 |
| AOF2 | BHC110 | KDM1 | KIAA0601 | LSD1 | amine oxidase (flavin containing) domain 2 | Two-hybrid | BioGRID | 16169070 |
| ARL15 | ARFRP2 | FLJ20051 | ADP-ribosylation factor-like 15 | Two-hybrid | BioGRID | 16169070 |
| BTBD2 | - | BTB (POZ) domain containing 2 | Two-hybrid | BioGRID | 16169070 |
| C11orf59 | FLJ20625 | chromosome 11 open reading frame 59 | Two-hybrid | BioGRID | 16169070 |
| C11orf79 | FLJ20487 | chromosome 11 open reading frame 79 | Two-hybrid | BioGRID | 16169070 |
| CDKN2B | CDK4I | INK4B | MTS2 | P15 | TP15 | p15INK4b | cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4) | Two-hybrid | BioGRID | 16169070 |
| CDKN2C | INK4C | p18 | p18-INK4C | cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4) | Two-hybrid | BioGRID | 16169070 |
| DLEU1 | BCMS | DLB1 | DLEU2 | LEU1 | LEU2 | MGC22430 | NCRNA00021 | XTP6 | deleted in lymphocytic leukemia 1 (non-protein coding) | Two-hybrid | BioGRID | 16169070 |
| EIF2S2 | DKFZp686L18198 | EIF2 | EIF2B | EIF2beta | MGC8508 | eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa | Two-hybrid | BioGRID | 16169070 |
| FXYD6 | - | FXYD domain containing ion transport regulator 6 | Two-hybrid | BioGRID | 16169070 |
| NACA | HSD48 | MGC117224 | NACA1 | nascent polypeptide-associated complex alpha subunit | Two-hybrid | BioGRID | 16169070 |
| NP | FLJ94043 | FLJ97288 | FLJ97312 | MGC117396 | MGC125915 | MGC125916 | PNP | PRO1837 | PUNP | nucleoside phosphorylase | Two-hybrid | BioGRID | 16169070 |
| PAFAH1B3 | - | platelet-activating factor acetylhydrolase, isoform Ib, gamma subunit 29kDa | Two-hybrid | BioGRID | 16169070 |
| PCDHA4 | CNR1 | CNRN1 | CRNR1 | MGC138307 | MGC142169 | PCDH-ALPHA4 | protocadherin alpha 4 | Two-hybrid | BioGRID | 16169070 |
| PRDX5 | ACR1 | AOEB166 | B166 | MGC117264 | MGC142283 | MGC142285 | PLP | PMP20 | PRDX6 | PRXV | SBBI10 | peroxiredoxin 5 | Two-hybrid | BioGRID | 16169070 |
| PSMD11 | MGC3844 | Rpn6 | S9 | p44.5 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 11 | Two-hybrid | BioGRID | 16169070 |
| RGL2 | HKE1.5 | KE1.5 | RAB2L | ral guanine nucleotide dissociation stimulator-like 2 | Two-hybrid | BioGRID | 16169070 |
| RNF10 | KIAA0262 | MGC126758 | MGC126764 | RIE2 | ring finger protein 10 | Two-hybrid | BioGRID | 16169070 |
| SAT1 | DC21 | KFSD | SAT | SSAT | SSAT-1 | spermidine/spermine N1-acetyltransferase 1 | Two-hybrid | BioGRID | 16169070 |
| SERPINB9 | CAP-3 | CAP3 | PI9 | serpin peptidase inhibitor, clade B (ovalbumin), member 9 | Two-hybrid | BioGRID | 16169070 |
| TAC3 | NKB | NKNB | PRO1155 | ZNEUROK1 | tachykinin 3 | Two-hybrid | BioGRID | 16169070 |
| TK1 | TK2 | thymidine kinase 1, soluble | Two-hybrid | BioGRID | 16169070 |
| TSC22D1 | DKFZp686O19206 | MGC17597 | RP11-269C23.2 | TGFB1I4 | TSC22 | TSC22 domain family, member 1 | Two-hybrid | BioGRID | 16169070 |
Section V. Pathway annotation
| Pathway name | Pathway size | # SZGR 2.0 genes in pathway | Info |
|---|---|---|---|
| RHEIN ALL GLUCOCORTICOID THERAPY DN | 362 | 238 | All SZGR 2.0 genes in this pathway |
| CHOI ATL STAGE PREDICTOR | 44 | 24 | All SZGR 2.0 genes in this pathway |
| NUYTTEN EZH2 TARGETS DN | 1024 | 594 | All SZGR 2.0 genes in this pathway |
| BENPORATH CYCLING GENES | 648 | 385 | All SZGR 2.0 genes in this pathway |
| SHEN SMARCA2 TARGETS UP | 424 | 268 | All SZGR 2.0 genes in this pathway |
| LEE LIVER CANCER E2F1 DN | 64 | 42 | All SZGR 2.0 genes in this pathway |
| MONNIER POSTRADIATION TUMOR ESCAPE DN | 373 | 196 | All SZGR 2.0 genes in this pathway |
| ZHANG BREAST CANCER PROGENITORS UP | 425 | 253 | All SZGR 2.0 genes in this pathway |
| BERNARD PPAPDC1B TARGETS UP | 40 | 20 | All SZGR 2.0 genes in this pathway |
| MILI PSEUDOPODIA HAPTOTAXIS UP | 518 | 299 | All SZGR 2.0 genes in this pathway |
| WHITFIELD CELL CYCLE G2 M | 216 | 124 | All SZGR 2.0 genes in this pathway |
| BRUINS UVC RESPONSE LATE | 1137 | 655 | All SZGR 2.0 genes in this pathway |
| SMIRNOV RESPONSE TO IR 6HR UP | 166 | 97 | All SZGR 2.0 genes in this pathway |