Gene Page: RS1
Summary ?
GeneID | 6247 |
Symbol | RS1 |
Synonyms | RS|XLRS1 |
Description | retinoschisin 1 |
Reference | MIM:300839|HGNC:HGNC:10457|Ensembl:ENSG00000102104|HPRD:02426|Vega:OTTHUMG00000021216 |
Gene type | protein-coding |
Map location | Xp22.13 |
Gene in Data Sources
Gene set name | Method of gene set | Description | Info |
---|---|---|---|
CV:PGCnp | Genome-wide Association Study | GWAS | |
PMID:cooccur | High-throughput literature-search | Systematic search in PubMed for genes co-occurring with SCZ keywords. A total of 3027 genes were included. | |
Literature | High-throughput literature-search | Co-occurance with Schizophrenia keywords: schizophrenia,schizophrenias | Click to show details |
Section I. Genetics and epigenetics annotation
Section II. Transcriptome annotation
General gene expression (GTEx)
Gene expression of temporal and spatial changes (BrainSpan)
Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes the lower 25% and upper 25% of the expression distribution.
Top co-expressed genes in brain regions
Top 10 positively co-expressed genes | ||
Gene | Pearson's Correlation | Spearman's Correlation |
S100A8 | 0.96 | 0.88 |
S100A12 | 0.85 | 0.73 |
BCL2A1 | 0.78 | 0.58 |
VNN2 | 0.72 | 0.53 |
RNASE2 | 0.71 | 0.43 |
LYZ | 0.70 | 0.63 |
MMP9 | 0.68 | 0.42 |
C1QB | 0.67 | 0.44 |
FPR1 | 0.65 | 0.39 |
ELANE | 0.65 | 0.44 |
Top 10 negatively co-expressed genes | ||
Gene | Pearson's Correlation | Spearman's Correlation |
ANKRD11 | -0.41 | -0.45 |
MPRIP | -0.40 | -0.50 |
HNRNPUL2 | -0.38 | -0.54 |
GOLGA2 | -0.37 | -0.44 |
BOD1L | -0.37 | -0.49 |
MYO18A | -0.37 | -0.53 |
MYH10 | -0.37 | -0.50 |
MDN1 | -0.37 | -0.45 |
HERC1 | -0.37 | -0.61 |
SPTBN2 | -0.36 | -0.52 |
Section V. Pathway annotation
Pathway name | Pathway size | # SZGR 2.0 genes in pathway | Info |
---|---|---|---|
BROWNE HCMV INFECTION 48HR DN | 504 | 323 | All SZGR 2.0 genes in this pathway |
IVANOVA HEMATOPOIESIS STEM CELL AND PROGENITOR | 681 | 420 | All SZGR 2.0 genes in this pathway |
GRADE COLON CANCER UP | 871 | 505 | All SZGR 2.0 genes in this pathway |
YAGI AML WITH INV 16 TRANSLOCATION | 422 | 277 | All SZGR 2.0 genes in this pathway |