Gene Page: CCL24
Summary ?
| GeneID | 6369 |
| Symbol | CCL24 |
| Synonyms | Ckb-6|MPIF-2|MPIF2|SCYA24 |
| Description | C-C motif chemokine ligand 24 |
| Reference | MIM:602495|HGNC:HGNC:10623|HPRD:03931| |
| Gene type | protein-coding |
| Map location | 7q11.23 |
| Pascal p-value | 0.953 |
| Fetal beta | -0.14 |
Gene in Data Sources
| Gene set name | Method of gene set | Description | Info |
|---|---|---|---|
| CV:PGCnp | Genome-wide Association Study | GWAS | |
| PMID:cooccur | High-throughput literature-search | Systematic search in PubMed for genes co-occurring with SCZ keywords. A total of 3027 genes were included. | |
| Literature | High-throughput literature-search | Co-occurance with Schizophrenia keywords: schizophrenia,schizophrenic,schizophrenias | Click to show details |
Section I. Genetics and epigenetics annotation
Section II. Transcriptome annotation
General gene expression (GTEx)
Gene expression during devlopment (BrainCloud)
Footnote:
A total of 269 time points ploted, with n=38 fetal samples (x=1:38). Each triangle represents one time point.
Gene expression of temporal and spatial changes (BrainSpan)
Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes the lower 25% and upper 25% of the expression distribution.
Top co-expressed genes in brain regions
| Top 10 positively co-expressed genes | ||
| Gene | Pearson's Correlation | Spearman's Correlation |
| KDM6B | 0.91 | 0.83 |
| GTF2IRD1 | 0.90 | 0.86 |
| ZSWIM5 | 0.90 | 0.78 |
| SRC | 0.89 | 0.81 |
| XKR7 | 0.89 | 0.75 |
| ZNF362 | 0.89 | 0.79 |
| VARS | 0.89 | 0.82 |
| ISLR2 | 0.89 | 0.71 |
| PCGF2 | 0.88 | 0.83 |
| SMARCA4 | 0.88 | 0.81 |
| Top 10 negatively co-expressed genes | ||
| Gene | Pearson's Correlation | Spearman's Correlation |
| C5orf53 | -0.65 | -0.77 |
| HLA-F | -0.61 | -0.62 |
| SERPINB6 | -0.61 | -0.57 |
| TNFSF12 | -0.61 | -0.59 |
| SLC16A11 | -0.60 | -0.60 |
| SPARCL1 | -0.60 | -0.65 |
| CA4 | -0.60 | -0.71 |
| HEPN1 | -0.60 | -0.60 |
| PTH1R | -0.60 | -0.57 |
| CLU | -0.60 | -0.59 |
Section V. Pathway annotation
| Pathway name | Pathway size | # SZGR 2.0 genes in pathway | Info |
|---|---|---|---|
| KEGG CYTOKINE CYTOKINE RECEPTOR INTERACTION | 267 | 161 | All SZGR 2.0 genes in this pathway |
| KEGG CHEMOKINE SIGNALING PATHWAY | 190 | 128 | All SZGR 2.0 genes in this pathway |
| FULCHER INFLAMMATORY RESPONSE LECTIN VS LPS UP | 579 | 346 | All SZGR 2.0 genes in this pathway |
| RICKMAN TUMOR DIFFERENTIATED WELL VS POORLY DN | 382 | 224 | All SZGR 2.0 genes in this pathway |
| MARTENS TRETINOIN RESPONSE UP | 857 | 456 | All SZGR 2.0 genes in this pathway |
| PHESSE TARGETS OF APC AND MBD2 UP | 20 | 14 | All SZGR 2.0 genes in this pathway |
| ZWANG EGF INTERVAL UP | 105 | 46 | All SZGR 2.0 genes in this pathway |
| NABA SECRETED FACTORS | 344 | 197 | All SZGR 2.0 genes in this pathway |
| NABA MATRISOME ASSOCIATED | 753 | 411 | All SZGR 2.0 genes in this pathway |
| NABA MATRISOME | 1028 | 559 | All SZGR 2.0 genes in this pathway |