Gene Page: SNRPD3

Summary
GeneID  6634
Symbol  SNRPD3
Synonyms  SMD3
Description  small nuclear ribonucleoprotein D3 polypeptide 18kDa
See related  HGNC:11160|MIM:601062|Ensembl:ENSG00000100028|HPRD:03039|
Locus tag  -
Gene type  protein-coding
Map location  22q11.23
 
Gene in Data Sources
Gene set name Method of gene set Evidence Info
GSMA_Igenome scan meta-analysisPsr: 0.031 
 
General Gene Expression (microarray) ?
 
Gene Expression in Brain Regions (new)
 
Top co-expressed genes in Brain Regions (new)
GenePearson's Correlation Spearman's Correlation
Top 10 positively co-expressed genes
DNAH70.820.73
LRRC60.800.74
TSGA100.790.58
WDR660.790.67
UBXN100.780.69
CASC10.770.61
AC079354.20.770.56
CCDC390.760.65
AK70.760.62
NPHP10.750.58
Top 10 negatively co-expressed genes
AF347015.21-0.34-0.17
AF347015.2-0.31-0.17
MT-CO2-0.30-0.18
AF347015.18-0.30-0.13
AF347015.8-0.29-0.15
AC098691.2-0.29-0.25
AF347015.31-0.28-0.18
MT-CYB-0.27-0.14
AF347015.15-0.26-0.13
AF347015.33-0.26-0.13
Gene Ontology
Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0005515protein bindingIPI11714716 |11748230 |12065586 
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0000387spliceosomal snRNP biogenesisEXP15130578 
GO:0008380RNA splicingTAS1701240 
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0005829cytosolEXP10531003 
GO:0005634nucleusIEA-
GO:0005654nucleoplasmEXP10531003 
GO:0005681spliceosomeTAS7527560 
GO:0005730nucleolusIDA18029348 
GO:0005737cytoplasmIDA18029348 
GO:0030532small nuclear ribonucleoprotein complexTAS1701240 
 
Protein-protein InteractionsShown by network
InteractorsAliases BOfficial full name BExperimentalSourcePubMed ID
CLNS1ACLCI | CLNS1B | IClnchloride channel, nucleotide-sensitive, 1AAffinity Capture-Western
Reconstituted Complex		BioGRID11713266 
DDX20DKFZp434H052 | DP103 | GEMIN3DEAD (Asp-Glu-Ala-Asp) box polypeptide 20-HPRD,BioGRID10601333 
GEMIN5DKFZp586M1824 | MGC142174gem (nuclear organelle) associated protein 5-HPRD,BioGRID11714716 
GEMIN6FLJ23459gem (nuclear organelle) associated protein 6Gemin6 interacts with SNRPD3 (SmD3)BIND15939020 
Gemin6 interacts with SmD3.BIND11748230 
GEMIN7SIP3gem (nuclear organelle) associated protein 7GEMIN7 interacts with SNRPD3 (SmD3)BIND12065586 
LSM10MGC15749 | MST074 | MSTP074LSM10, U7 small nuclear RNA associatedAffinity Capture-MSBioGRID12975319 
LSM3SMX4 | USS2 | YLR438CLSM3 homolog, U6 small nuclear RNA associated (S. cerevisiae)-HPRD,BioGRID15231747 
LSM7YNL147WLSM7 homolog, U6 small nuclear RNA associated (S. cerevisiae)-HPRD,BioGRID15231747 
PRMT5HRMT1L5 | IBP72 | JBP1 | SKB1 | SKB1Hsprotein arginine methyltransferase 5-HPRD,BioGRID11713266 
RNU11U11RNA, U11 small nuclearAffinity Capture-MSBioGRID15146077 
RNU12U12RNA, U12 small nuclearAffinity Capture-MSBioGRID15146077 
SF3A2PRP11 | PRPF11 | SAP62 | SF3a66splicing factor 3a, subunit 2, 66kDaAffinity Capture-MSBioGRID12234937 
SFRS12DKFZp564B176 | MGC133045 | SRrp508 | SRrp86splicing factor, arginine/serine-rich 12-HPRD14559993 
SMN1BCD541 | SMA | SMA1 | SMA2 | SMA3 | SMA4 | SMA@ | SMN | SMNT | T-BCD541survival of motor neuron 1, telomericReconstituted ComplexBioGRID10851237 
SMN2BCD541 | C-BCD541 | FLJ76644 | MGC20996 | MGC5208 | SMNCsurvival of motor neuron 2, centromeric-HPRD9323129 
SNRPBCOD | SNRPB1 | SmB/SmB' | snRNP-Bsmall nuclear ribonucleoprotein polypeptides B and B1-HPRD,BioGRID10025403 
SNRPEB-raf | SMEsmall nuclear ribonucleoprotein polypeptide ETwo-hybridBioGRID9417867 
SNRPD3 interacts with SNRPE.BIND9417867 
SNRPGMGC117317 | SMGsmall nuclear ribonucleoprotein polypeptide GTwo-hybridBioGRID9417867 
SNRPD3 interacts with SNRPG.BIND9417867 
SNRPNDKFZp686C0927 | DKFZp686M12165 | DKFZp761I1912 | DKFZp762N022 | FLJ33569 | FLJ36996 | FLJ39265 | HCERN3 | MGC29886 | PWCR | RT-LI | SM-D | SMN | SNRNP-N | SNURF-SNRPNsmall nuclear ribonucleoprotein polypeptide NSNRPD3 interacts with SNRPN.BIND9417867 
Two-hybridBioGRID9417867 
STXBP3MUNC18-3 | MUNC18C | PSP | UNC-18Csyntaxin binding protein 3-HPRD12065586 
WDR77HKMT1069 | MEP50 | MGC2722 | Nbla10071 | RP11-552M11.3 | p44WD repeat domain 77-HPRD,BioGRID11756452 
 
Pathway annotation
Pathway namePathway size# SZGR genes in pathwayInfo
KEGG_SPLICEOSOME 12872All SZGR genes in this pathway
KEGG_SYSTEMIC_LUPUS_ERYTHEMATOSUS 140100All SZGR genes in this pathway
REACTOME_METABOLISM_OF_NON_CODING_RNA 4929All SZGR genes in this pathway
REACTOME_PROCESSING_OF_CAPPED_INTRON_CONTAINING_PRE_MRNA 14077All SZGR genes in this pathway
REACTOME_SLBP_DEPENDENT_PROCESSING_OF_REPLICATION_DEPENDENT_HISTONE_PRE_MRNAS 115All SZGR genes in this pathway
REACTOME_RNA_POL_II_TRANSCRIPTION 10554All SZGR genes in this pathway
REACTOME_MRNA_PROCESSING 16186All SZGR genes in this pathway
REACTOME_MRNA_SPLICING 11158All SZGR genes in this pathway
REACTOME_MRNA_SPLICING_MINOR_PATHWAY 4519All SZGR genes in this pathway
REACTOME_PROCESSING_OF_CAPPED_INTRONLESS_PRE_MRNA 2310All SZGR genes in this pathway
REACTOME_TRANSCRIPTION 210127All SZGR genes in this pathway
REACTOME_METABOLISM_OF_RNA 330155All SZGR genes in this pathway
REACTOME_CLEAVAGE_OF_GROWING_TRANSCRIPT_IN_THE_TERMINATION_REGION_ 4422All SZGR genes in this pathway
GARY_CD5_TARGETS_DN 431263All SZGR genes in this pathway
DIAZ_CHRONIC_MEYLOGENOUS_LEUKEMIA_UP 1382904All SZGR genes in this pathway
RHEIN_ALL_GLUCOCORTICOID_THERAPY_DN 362238All SZGR genes in this pathway
TIEN_INTESTINE_PROBIOTICS_24HR_UP 557331All SZGR genes in this pathway
OUELLET_OVARIAN_CANCER_INVASIVE_VS_LMP_UP 11785All SZGR genes in this pathway
BERENJENO_TRANSFORMED_BY_RHOA_UP 536340All SZGR genes in this pathway
MATTIOLI_MGUS_VS_PCL 11662All SZGR genes in this pathway
JAERVINEN_AMPLIFIED_IN_LARYNGEAL_CANCER 4024All SZGR genes in this pathway
PUJANA_BRCA1_PCC_NETWORK 16521023All SZGR genes in this pathway
PUJANA_CHEK2_PCC_NETWORK 779480All SZGR genes in this pathway
FERREIRA_EWINGS_SARCOMA_UNSTABLE_VS_STABLE_UP 16792All SZGR genes in this pathway
SCHAEFFER_PROSTATE_DEVELOPMENT_6HR_DN 514330All SZGR genes in this pathway
SCHAEFFER_PROSTATE_DEVELOPMENT_12HR_UP 11679All SZGR genes in this pathway
BENPORATH_SOX2_TARGETS 734436All SZGR genes in this pathway
BENPORATH_MYC_MAX_TARGETS 775494All SZGR genes in this pathway
MANALO_HYPOXIA_DN 289166All SZGR genes in this pathway
TARTE_PLASMA_CELL_VS_PLASMABLAST_DN 309206All SZGR genes in this pathway
FLECHNER_BIOPSY_KIDNEY_TRANSPLANT_REJECTED_VS_OK_DN 546351All SZGR genes in this pathway
FLECHNER_BIOPSY_KIDNEY_TRANSPLANT_OK_VS_DONOR_UP 555346All SZGR genes in this pathway
ZHAN_MULTIPLE_MYELOMA_SUBGROUPS 3020All SZGR genes in this pathway
SESTO_RESPONSE_TO_UV_C4 2014All SZGR genes in this pathway
KAYO_AGING_MUSCLE_DN 12376All SZGR genes in this pathway
CLAUS_PGR_POSITIVE_MENINGIOMA_UP 107All SZGR genes in this pathway
BONOME_OVARIAN_CANCER_SURVIVAL_OPTIMAL_DEBULKING 246152All SZGR genes in this pathway
GRADE_COLON_CANCER_UP 871505All SZGR genes in this pathway
CHAUHAN_RESPONSE_TO_METHOXYESTRADIOL_UP 5132All SZGR genes in this pathway
AGUIRRE_PANCREATIC_CANCER_COPY_NUMBER_DN 238145All SZGR genes in this pathway
DANG_REGULATED_BY_MYC_UP 7253All SZGR genes in this pathway
DANG_MYC_TARGETS_UP 143100All SZGR genes in this pathway
DANG_BOUND_BY_MYC 1103714All SZGR genes in this pathway
YAO_TEMPORAL_RESPONSE_TO_PROGESTERONE_CLUSTER_14 14386All SZGR genes in this pathway
BRUINS_UVC_RESPONSE_VIA_TP53_GROUP_B 549316All SZGR genes in this pathway
BILANGES_SERUM_SENSITIVE_VIA_TSC2 3925All SZGR genes in this pathway
KIM_TIAL1_TARGETS 3222All SZGR genes in this pathway
WAKABAYASHI_ADIPOGENESIS_PPARG_RXRA_BOUND_8D 882506All SZGR genes in this pathway
ABRAMSON_INTERACT_WITH_AIRE 4533All SZGR genes in this pathway


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