Gene Page: ZNF208
Summary ?
| GeneID | 7757 |
| Symbol | ZNF208 |
| Synonyms | PMIDP|ZNF95 |
| Description | zinc finger protein 208 |
| Reference | MIM:603977|HGNC:HGNC:12999|HPRD:05998| |
| Gene type | protein-coding |
| Map location | 19p12 |
| Pascal p-value | 0.976 |
| DMG | 1 (# studies) |
| eGene | Caudate basal ganglia |
Gene in Data Sources
| Gene set name | Method of gene set | Description | Info |
|---|---|---|---|
| CV:PGCnp | Genome-wide Association Study | GWAS | |
| DMG:Wockner_2014 | Genome-wide DNA methylation analysis | This dataset includes 4641 differentially methylated probes corresponding to 2929 unique genes between schizophrenia patients (n=24) and controls (n=24). | 1 |
Section I. Genetics and epigenetics annotation
Differentially methylated gene
| Probe | Chromosome | Position | Nearest gene | P (dis) | Beta (dis) | FDR (dis) | Study |
|---|---|---|---|---|---|---|---|
| cg18500360 | 19 | 22193293 | ZNF208 | 4.87E-5 | 0.552 | 0.021 | DMG:Wockner_2014 |
Section II. Transcriptome annotation
General gene expression (GTEx)
Gene expression of temporal and spatial changes (BrainSpan)
Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes the lower 25% and upper 25% of the expression distribution.
Top co-expressed genes in brain regions
| Top 10 positively co-expressed genes | ||
| Gene | Pearson's Correlation | Spearman's Correlation |
| MAPK8 | 0.96 | 0.95 |
| CSNK1A1 | 0.95 | 0.96 |
| PPP2R5E | 0.95 | 0.96 |
| PAPOLG | 0.95 | 0.95 |
| EXOC2 | 0.94 | 0.95 |
| POLR2B | 0.94 | 0.94 |
| CAPRIN1 | 0.94 | 0.96 |
| SPAST | 0.93 | 0.95 |
| MATR3 | 0.93 | 0.96 |
| CTDSPL2 | 0.93 | 0.96 |
| Top 10 negatively co-expressed genes | ||
| Gene | Pearson's Correlation | Spearman's Correlation |
| FXYD1 | -0.72 | -0.89 |
| AC018755.7 | -0.71 | -0.78 |
| MT-CO2 | -0.71 | -0.87 |
| AIFM3 | -0.70 | -0.79 |
| HLA-F | -0.70 | -0.78 |
| AF347015.33 | -0.70 | -0.85 |
| AF347015.31 | -0.70 | -0.84 |
| HSD17B14 | -0.70 | -0.80 |
| HEPN1 | -0.69 | -0.78 |
| TSC22D4 | -0.69 | -0.80 |
Section V. Pathway annotation
| Pathway name | Pathway size | # SZGR 2.0 genes in pathway | Info |
|---|---|---|---|
| REACTOME GENERIC TRANSCRIPTION PATHWAY | 352 | 181 | All SZGR 2.0 genes in this pathway |
| KAAB HEART ATRIUM VS VENTRICLE UP | 249 | 170 | All SZGR 2.0 genes in this pathway |