Gene Page: FBXL15
Summary ?
GeneID | 79176 |
Symbol | FBXL15 |
Synonyms | FBXO37|Fbl15|JET|PSD |
Description | F-box and leucine-rich repeat protein 15 |
Reference | MIM:610287|HGNC:HGNC:28155|Ensembl:ENSG00000107872|Vega:OTTHUMG00000018957 |
Gene type | protein-coding |
Map location | 10q24.32 |
Pascal p-value | 2.344E-4 |
Sherlock p-value | 0.895 |
Gene in Data Sources
Gene set name | Method of gene set | Description | Info |
---|---|---|---|
CV:PGCnp | Genome-wide Association Study | GWAS |
Section I. Genetics and epigenetics annotation
Section II. Transcriptome annotation
General gene expression (GTEx)
Gene expression of temporal and spatial changes (BrainSpan)
Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes the lower 25% and upper 25% of the expression distribution.
Top co-expressed genes in brain regions
Top 10 positively co-expressed genes | ||
Gene | Pearson's Correlation | Spearman's Correlation |
SULT1A1 | 0.83 | 0.80 |
MARCH2 | 0.82 | 0.78 |
C12orf62 | 0.82 | 0.81 |
PNKD | 0.80 | 0.77 |
ASPDH | 0.80 | 0.76 |
CISD3 | 0.80 | 0.79 |
RHBDL1 | 0.79 | 0.82 |
UROD | 0.79 | 0.75 |
ACYP2 | 0.79 | 0.79 |
GSTK1 | 0.78 | 0.70 |
Top 10 negatively co-expressed genes | ||
Gene | Pearson's Correlation | Spearman's Correlation |
THOC2 | -0.52 | -0.59 |
ZNF326 | -0.51 | -0.58 |
DACT1 | -0.51 | -0.52 |
ZNF238 | -0.51 | -0.49 |
ISLR2 | -0.51 | -0.47 |
TMEM108 | -0.50 | -0.52 |
ZEB2 | -0.50 | -0.54 |
SLA | -0.50 | -0.50 |
ATAD2B | -0.50 | -0.57 |
KLHL1 | -0.50 | -0.50 |
Section V. Pathway annotation
Pathway name | Pathway size | # SZGR 2.0 genes in pathway | Info |
---|---|---|---|
GARGALOVIC RESPONSE TO OXIDIZED PHOSPHOLIPIDS BLUE DN | 61 | 35 | All SZGR 2.0 genes in this pathway |
LASTOWSKA NEUROBLASTOMA COPY NUMBER DN | 800 | 473 | All SZGR 2.0 genes in this pathway |
FERREIRA EWINGS SARCOMA UNSTABLE VS STABLE DN | 98 | 59 | All SZGR 2.0 genes in this pathway |
STEIN ESRRA TARGETS UP | 388 | 234 | All SZGR 2.0 genes in this pathway |
STEIN ESRRA TARGETS | 535 | 325 | All SZGR 2.0 genes in this pathway |