Summary ?
GeneID79176
SymbolFBXL15
SynonymsFBXO37|Fbl15|JET|PSD
DescriptionF-box and leucine-rich repeat protein 15
ReferenceMIM:610287|HGNC:HGNC:28155|Ensembl:ENSG00000107872|Vega:OTTHUMG00000018957
Gene typeprotein-coding
Map location10q24.32
Pascal p-value2.344E-4
Sherlock p-value0.895

Gene in Data Sources
Gene set name Method of gene setDescriptionInfo
CV:PGCnpGenome-wide Association StudyGWAS

Section I. Genetics and epigenetics annotation


Section II. Transcriptome annotation

General gene expression (GTEx)

Not available

Gene expression of temporal and spatial changes (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes the lower 25% and upper 25% of the expression distribution.

Top co-expressed genes in brain regions

Top 10 positively co-expressed genes
GenePearson's Correlation Spearman's Correlation
SULT1A10.830.80
MARCH20.820.78
C12orf620.820.81
PNKD0.800.77
ASPDH0.800.76
CISD30.800.79
RHBDL10.790.82
UROD0.790.75
ACYP20.790.79
GSTK10.780.70
Top 10 negatively co-expressed genes
GenePearson's Correlation Spearman's Correlation
THOC2-0.52-0.59
ZNF326-0.51-0.58
DACT1-0.51-0.52
ZNF238-0.51-0.49
ISLR2-0.51-0.47
TMEM108-0.50-0.52
ZEB2-0.50-0.54
SLA-0.50-0.50
ATAD2B-0.50-0.57
KLHL1-0.50-0.50

Section V. Pathway annotation

Pathway namePathway size# SZGR 2.0 genes in pathwayInfo
GARGALOVIC RESPONSE TO OXIDIZED PHOSPHOLIPIDS BLUE DN 6135All SZGR 2.0 genes in this pathway
LASTOWSKA NEUROBLASTOMA COPY NUMBER DN 800473All SZGR 2.0 genes in this pathway
FERREIRA EWINGS SARCOMA UNSTABLE VS STABLE DN 9859All SZGR 2.0 genes in this pathway
STEIN ESRRA TARGETS UP 388234All SZGR 2.0 genes in this pathway
STEIN ESRRA TARGETS 535325All SZGR 2.0 genes in this pathway