Gene Page: B3GNT4
Summary ?
| GeneID | 79369 |
| Symbol | B3GNT4 |
| Synonyms | B3GN-T4|beta3Gn-T4 |
| Description | UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 4 |
| Reference | MIM:605864|HGNC:HGNC:15683|Ensembl:ENSG00000176383|HPRD:12058|Vega:OTTHUMG00000168917 |
| Gene type | protein-coding |
| Map location | 12q24 |
| Pascal p-value | 0.002 |
| Sherlock p-value | 0.263 |
| eGene | Cerebellum Myers' cis & trans |
Gene in Data Sources
| Gene set name | Method of gene set | Description | Info |
|---|---|---|---|
| CV:PGCnp | Genome-wide Association Study | GWAS |
Section I. Genetics and epigenetics annotation
eQTL annotation
| SNP ID | Chromosome | Position | eGene | Gene Entrez ID | pvalue | qvalue | TSS distance | eQTL type |
|---|---|---|---|---|---|---|---|---|
| rs7174702 | chr15 | 23764446 | B3GNT4 | 79369 | 0.15 | trans |
Section II. Transcriptome annotation
General gene expression (GTEx)
Gene expression of temporal and spatial changes (BrainSpan)
Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes the lower 25% and upper 25% of the expression distribution.
Top co-expressed genes in brain regions
| Top 10 positively co-expressed genes | ||
| Gene | Pearson's Correlation | Spearman's Correlation |
| RDH12 | 0.90 | 0.81 |
| CPNE9 | 0.89 | 0.85 |
| PTPN3 | 0.86 | 0.60 |
| TPH2 | 0.85 | 0.68 |
| PAPPA | 0.85 | 0.28 |
| SSTR3 | 0.84 | 0.80 |
| FAM19A4 | 0.84 | 0.76 |
| MEI1 | 0.83 | 0.61 |
| KCNK13 | 0.83 | 0.58 |
| VWC2 | 0.82 | 0.62 |
| Top 10 negatively co-expressed genes | ||
| Gene | Pearson's Correlation | Spearman's Correlation |
| PLEKHO1 | -0.35 | -0.57 |
| RBMX2 | -0.35 | -0.72 |
| TUBB2B | -0.35 | -0.72 |
| KIAA1949 | -0.34 | -0.64 |
| SMURF2 | -0.34 | -0.63 |
| CARHSP1 | -0.34 | -0.76 |
| FADS2 | -0.34 | -0.63 |
| TRAF4 | -0.34 | -0.71 |
| TIGD1 | -0.33 | -0.65 |
| YBX1 | -0.33 | -0.66 |
Section V. Pathway annotation
| Pathway name | Pathway size | # SZGR 2.0 genes in pathway | Info |
|---|---|---|---|
| KEGG GLYCOSPHINGOLIPID BIOSYNTHESIS LACTO AND NEOLACTO SERIES | 26 | 19 | All SZGR 2.0 genes in this pathway |
| REACTOME O LINKED GLYCOSYLATION OF MUCINS | 59 | 29 | All SZGR 2.0 genes in this pathway |
| REACTOME KERATAN SULFATE BIOSYNTHESIS | 26 | 18 | All SZGR 2.0 genes in this pathway |
| REACTOME KERATAN SULFATE KERATIN METABOLISM | 30 | 21 | All SZGR 2.0 genes in this pathway |
| REACTOME GLYCOSAMINOGLYCAN METABOLISM | 111 | 69 | All SZGR 2.0 genes in this pathway |
| REACTOME METABOLISM OF PROTEINS | 518 | 242 | All SZGR 2.0 genes in this pathway |
| REACTOME POST TRANSLATIONAL PROTEIN MODIFICATION | 188 | 116 | All SZGR 2.0 genes in this pathway |
| REACTOME METABOLISM OF CARBOHYDRATES | 247 | 154 | All SZGR 2.0 genes in this pathway |
| ELVIDGE HYPOXIA UP | 171 | 112 | All SZGR 2.0 genes in this pathway |
| ELVIDGE HIF1A TARGETS DN | 91 | 58 | All SZGR 2.0 genes in this pathway |
| SHEN SMARCA2 TARGETS DN | 357 | 212 | All SZGR 2.0 genes in this pathway |
| MOREAUX MULTIPLE MYELOMA BY TACI UP | 412 | 249 | All SZGR 2.0 genes in this pathway |
| WEST ADRENOCORTICAL TUMOR DN | 546 | 362 | All SZGR 2.0 genes in this pathway |
| WAKABAYASHI ADIPOGENESIS PPARG RXRA BOUND 8D | 882 | 506 | All SZGR 2.0 genes in this pathway |