Gene Page: NAA16
Summary ?
| GeneID | 79612 |
| Symbol | NAA16 |
| Synonyms | NARG1L |
| Description | N(alpha)-acetyltransferase 16, NatA auxiliary subunit |
| Reference | HGNC:HGNC:26164|Ensembl:ENSG00000172766|HPRD:07977|Vega:OTTHUMG00000016791 |
| Gene type | protein-coding |
| Map location | 13q14.11 |
| Pascal p-value | 4.858E-4 |
| Sherlock p-value | 0.668 |
| eGene | Myers' cis & trans |
Gene in Data Sources
| Gene set name | Method of gene set | Description | Info |
|---|---|---|---|
| CV:PGCnp | Genome-wide Association Study | GWAS |
Section I. Genetics and epigenetics annotation
eQTL annotation
| SNP ID | Chromosome | Position | eGene | Gene Entrez ID | pvalue | qvalue | TSS distance | eQTL type |
|---|---|---|---|---|---|---|---|---|
| snp_a-1856993 | 0 | NAA16 | 79612 | 0.19 | trans |
Section II. Transcriptome annotation
General gene expression (GTEx)
Gene expression of temporal and spatial changes (BrainSpan)
Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes the lower 25% and upper 25% of the expression distribution.
Top co-expressed genes in brain regions
| Top 10 positively co-expressed genes | ||
| Gene | Pearson's Correlation | Spearman's Correlation |
| CGGBP1 | 0.95 | 0.96 |
| FEM1B | 0.94 | 0.96 |
| SPIN1 | 0.94 | 0.95 |
| KBTBD7 | 0.94 | 0.95 |
| YTHDF3 | 0.93 | 0.96 |
| KBTBD6 | 0.93 | 0.95 |
| AP003115.1 | 0.93 | 0.95 |
| ZNF436 | 0.93 | 0.94 |
| ASB7 | 0.93 | 0.94 |
| AP2B1 | 0.93 | 0.94 |
| Top 10 negatively co-expressed genes | ||
| Gene | Pearson's Correlation | Spearman's Correlation |
| FXYD1 | -0.73 | -0.83 |
| MT-CO2 | -0.73 | -0.84 |
| AF347015.31 | -0.72 | -0.82 |
| AF347015.33 | -0.70 | -0.79 |
| MT-CYB | -0.69 | -0.80 |
| AF347015.8 | -0.69 | -0.82 |
| HSD17B14 | -0.69 | -0.76 |
| AF347015.27 | -0.69 | -0.80 |
| AIFM3 | -0.68 | -0.72 |
| S100B | -0.68 | -0.77 |
Section III. Gene Ontology annotation
| Molecular function | GO term | Evidence | Neuro keywords | PubMed ID |
|---|---|---|---|---|
| GO:0005515 | protein binding | ISS | - | |
| GO:0016407 | acetyltransferase activity | ISS | - | |
| GO:0043022 | ribosome binding | ISS | - | |
| Biological process | GO term | Evidence | Neuro keywords | PubMed ID |
| GO:0006474 | N-terminal protein amino acid acetylation | ISS | - | |
| GO:0045893 | positive regulation of transcription, DNA-dependent | ISS | - | |
| Cellular component | GO term | Evidence | Neuro keywords | PubMed ID |
| GO:0005634 | nucleus | ISS | - | |
| GO:0005667 | transcription factor complex | ISS | - | |
| GO:0005737 | cytoplasm | ISS | - |
Section V. Pathway annotation
| Pathway name | Pathway size | # SZGR 2.0 genes in pathway | Info |
|---|---|---|---|
| ZHOU INFLAMMATORY RESPONSE LIVE DN | 384 | 220 | All SZGR 2.0 genes in this pathway |
| GINESTIER BREAST CANCER 20Q13 AMPLIFICATION DN | 180 | 101 | All SZGR 2.0 genes in this pathway |
| MULLIGHAN MLL SIGNATURE 1 DN | 242 | 165 | All SZGR 2.0 genes in this pathway |
| MULLIGHAN MLL SIGNATURE 2 DN | 281 | 186 | All SZGR 2.0 genes in this pathway |
| ZHOU INFLAMMATORY RESPONSE FIMA DN | 284 | 156 | All SZGR 2.0 genes in this pathway |
| VANHARANTA UTERINE FIBROID WITH 7Q DELETION UP | 67 | 37 | All SZGR 2.0 genes in this pathway |
| NUYTTEN EZH2 TARGETS DN | 1024 | 594 | All SZGR 2.0 genes in this pathway |
| MONNIER POSTRADIATION TUMOR ESCAPE UP | 393 | 244 | All SZGR 2.0 genes in this pathway |
| MARSON BOUND BY FOXP3 UNSTIMULATED | 1229 | 713 | All SZGR 2.0 genes in this pathway |
| RATTENBACHER BOUND BY CELF1 | 467 | 251 | All SZGR 2.0 genes in this pathway |