Gene Page: SYNDIG1
Summary ?
| GeneID | 79953 |
| Symbol | SYNDIG1 |
| Synonyms | C20orf39|DSPC2|IFITMD5|TMEM90B |
| Description | synapse differentiation inducing 1 |
| Reference | MIM:614311|HGNC:HGNC:15885|Ensembl:ENSG00000101463|HPRD:12766|Vega:OTTHUMG00000032104 |
| Gene type | protein-coding |
| Map location | 20p11.21 |
| Pascal p-value | 0.489 |
| Sherlock p-value | 0.378 |
| Fetal beta | -1.035 |
Gene in Data Sources
| Gene set name | Method of gene set | Description | Info |
|---|---|---|---|
| CV:GWASdb | Genome-wide Association Studies | GWASdb records for schizophrenia | |
| CV:PGCnp | Genome-wide Association Study | GWAS |
Section I. Genetics and epigenetics annotation
eQTL annotation
| SNP ID | Chromosome | Position | eGene | Gene Entrez ID | pvalue | qvalue | TSS distance | eQTL type |
|---|---|---|---|---|---|---|---|---|
| rs16827037 | chr3 | 117203284 | TMEM90B | 79953 | 0.01 | trans | ||
| rs1020772 | chr9 | 76532511 | TMEM90B | 79953 | 0.1 | trans | ||
| rs12276 | chr19 | 58154091 | TMEM90B | 79953 | 0.05 | trans | ||
| rs10409262 | chr19 | 58154954 | TMEM90B | 79953 | 0.08 | trans |
Section II. Transcriptome annotation
General gene expression (GTEx)
Gene expression during devlopment (BrainCloud)
Footnote:
A total of 269 time points ploted, with n=38 fetal samples (x=1:38). Each triangle represents one time point.
Gene expression of temporal and spatial changes (BrainSpan)
Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes the lower 25% and upper 25% of the expression distribution.
No co-expressed genes in brain regions
Section V. Pathway annotation
| Pathway name | Pathway size | # SZGR 2.0 genes in pathway | Info |
|---|---|---|---|
| DELYS THYROID CANCER DN | 232 | 154 | All SZGR 2.0 genes in this pathway |
| MOHANKUMAR TLX1 TARGETS DN | 193 | 112 | All SZGR 2.0 genes in this pathway |
| ZHAN MULTIPLE MYELOMA MF UP | 47 | 27 | All SZGR 2.0 genes in this pathway |
| WALLACE PROSTATE CANCER RACE UP | 299 | 167 | All SZGR 2.0 genes in this pathway |
| BHAT ESR1 TARGETS NOT VIA AKT1 UP | 211 | 131 | All SZGR 2.0 genes in this pathway |
| BHAT ESR1 TARGETS VIA AKT1 UP | 281 | 183 | All SZGR 2.0 genes in this pathway |