Summary ?
GeneID801
SymbolCALM1
SynonymsCALML2|CAMI|CPVT4|DD132|LQT14|PHKD|caM
Descriptioncalmodulin 1 (phosphorylase kinase, delta)
ReferenceMIM:114180|HGNC:HGNC:1442|Ensembl:ENSG00000198668|HPRD:00241|Vega:OTTHUMG00000171044
Gene typeprotein-coding
Map location14q32.11
Pascal p-value0.044
Sherlock p-value0.768
Fetal beta-0.689
DMG2 (# studies)
SupportINTRACELLULAR SIGNAL TRANSDUCTION
SEROTONIN
G2Cdb.human_mGluR5
G2Cdb.human_PocklingtonH1
G2Cdb.humanNRC
G2Cdb.humanPSD
G2Cdb.humanPSP
CompositeSet
Darnell FMRP targets

Gene in Data Sources
Gene set name Method of gene setDescriptionInfo
ADT:Sun_2012Systematic Investigation of Antipsychotic Drugs and Their TargetsA total of 382 drug-target associations involving 43 antipsychotic drugs and 49 target genes.
CV:PGCnpGenome-wide Association StudyGWAS
DMG:Jaffe_2016Genome-wide DNA methylation analysisThis dataset includes 2,104 probes/CpGs associated with SZ patients (n=108) compared to 136 controls at Bonferroni-adjusted P < 0.05. 3
DMG:vanEijk_2014Genome-wide DNA methylation analysisThis dataset includes 432 differentially methylated CpG sites corresponding to 391 unique transcripts between schizophrenia patients (n=260) and unaffected controls (n=250). 3
PMID:cooccurHigh-throughput literature-searchSystematic search in PubMed for genes co-occurring with SCZ keywords. A total of 3027 genes were included.
LiteratureHigh-throughput literature-searchCo-occurance with Schizophrenia keywords: schizophrenia,schizophreniasClick to show details
NetworkShortest path distance of core genes in the Human protein-protein interaction networkContribution to shortest path in PPI network: 14.7236 

Section I. Genetics and epigenetics annotation

@Differentially methylated gene

ProbeChromosomePositionNearest geneP (dis)Beta (dis)FDR (dis)Study
cg203283281490863801CALM19.98E-9-0.014.36E-6DMG:Jaffe_2016
cg101732401490849342CALM13.41E-8-0.0211.02E-5DMG:Jaffe_2016
cg126246411490420569CALM10.0013.969DMG:vanEijk_2014


Section II. Transcriptome annotation

General gene expression (GTEx)

Not available

Gene expression during devlopment (BrainCloud)

Footnote:
A total of 269 time points ploted, with n=38 fetal samples (x=1:38). Each triangle represents one time point.

Gene expression of temporal and spatial changes (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes the lower 25% and upper 25% of the expression distribution.

Top co-expressed genes in brain regions

Top 10 positively co-expressed genes
GenePearson's Correlation Spearman's Correlation
CACYBP0.880.93
ATP6V1D0.840.89
SNX30.840.87
NKIRAS10.830.88
TCEAL70.830.92
NAT50.820.88
NDUFAF40.820.86
NDUFA50.810.85
TTC10.810.86
CISD10.810.86
Top 10 negatively co-expressed genes
GenePearson's Correlation Spearman's Correlation
SMTN-0.50-0.55
SLC27A1-0.49-0.50
FAM59B-0.48-0.50
RP4-697K14.1-0.48-0.55
PLXNB1-0.48-0.50
TENC1-0.47-0.47
NFKB2-0.47-0.51
AC010618.2-0.47-0.50
CDC42EP4-0.46-0.50
SEMA4B-0.46-0.46

Section IV. Protein-protein interaction annotation

InteractorsAliases BOfficial full name BExperimentalSourcePubMed ID
ADCYAP1R1PAC1 | PACAPR | PACAPRIadenylate cyclase activating polypeptide 1 (pituitary) receptor type ICalmodulin interacts with PACPR.BIND15670850 
ADD1ADDA | MGC3339 | MGC44427adducin 1 (alpha)Phenotypic SuppressionBioGRID8626479 
ADD1ADDA | MGC3339 | MGC44427adducin 1 (alpha)-HPRD8663089 
ADD2ADDBadducin 2 (beta)-HPRD7490111 
AKAP9AKAP350 | AKAP450 | CG-NAP | HYPERION | KIAA0803 | MU-RMS-40.16A | PRKA9 | YOTIAOA kinase (PRKA) anchor protein (yotiao) 9Affinity Capture-Western
Reconstituted Complex
BioGRID12221128 
ARAIS | DHTR | HUMARA | KD | NR3C4 | SBMA | SMAX1 | TFMandrogen receptorAffinity Capture-Western
Co-localization
Reconstituted Complex
BioGRID14695896 
ASCL2ASH2 | HASH2 | MASH2 | bHLHa45achaete-scute complex homolog 2 (Drosophila)-HPRD10757985 
CABIN1CAIN | KIAA0330 | PPP3INcalcineurin binding protein 1CALM1 (CaM) interacts with CABIN1. This interaction was modelled on a demonstrated interaction between CaM from an unspecified species and human CABIN1.BIND15902271 
CALCRCRT | CTR | CTR1calcitonin receptorCalmodulin interacts with CALTR.BIND15670850 
CALD1CDM | H-CAD | L-CAD | MGC21352 | NAG22caldesmon 1-HPRD11736632 
CAMK2GCAMK | CAMK-II | CAMKG | FLJ16043 | MGC26678calcium/calmodulin-dependent protein kinase II gamma-HPRD,BioGRID10860555 
CCNA2CCN1 | CCNAcyclin A2Reconstituted ComplexBioGRID14695896 
CCND1BCL1 | D11S287E | PRAD1 | U21B31cyclin D1-HPRD9837900 
CNN1SMCC | Sm-Calpcalponin 1, basic, smooth muscle-HPRD,BioGRID2161834 |2455687 
CRHR1CRF-R | CRF1 | CRFR1 | CRH-R1h | CRHR | CRHR1fcorticotropin releasing hormone receptor 1Calmodulin interacts with CRF1R.BIND15670850 
EDF1EDF-1 | MBF1 | MGC9058endothelial differentiation-related factor 1-HPRD10816571 
EGFRERBB | ERBB1 | HER1 | PIG61 | mENAepidermal growth factor receptor (erythroblastic leukemia viral (v-erb-b) oncogene homolog, avian)EGFR interacts with calmodulinBIND14960328 
ESR1DKFZp686N23123 | ER | ESR | ESRA | Era | NR3A1estrogen receptor 1-HPRD11981030 
ESR2ER-BETA | ESR-BETA | ESRB | ESTRB | Erb | NR3A2estrogen receptor 2 (ER beta)-HPRD11981030 
EWSR1EWSEwing sarcoma breakpoint region 1Reconstituted ComplexBioGRID9341188 
GAP43B-50 | PP46growth associated protein 43GAP-43 interacts with CaM.BIND8872303 
GLP1RMGC138331glucagon-like peptide 1 receptorCalmodulin interacts with GLP1R.BIND15670850 
GLP2R-glucagon-like peptide 2 receptorCalmodulin interacts with GLP2R.BIND15670850 
GRB7-growth factor receptor-bound protein 7Grb7 interacts with CaM. This interaction was modeled on a demonstrated interaction between human Grb7 and CaM from rat and an unspecified species.BIND15806159 
GRK1GPRK1 | RHOK | RKG protein-coupled receptor kinase 1-HPRD9753452 
GRK4GPRK2L | GPRK4 | GRK4a | IT11G protein-coupled receptor kinase 4Reconstituted ComplexBioGRID9092566 
GRK5GPRK5G protein-coupled receptor kinase 5Reconstituted ComplexBioGRID9092566 
GRM5GPRC1E | MGLUR5 | MGLUR5A | MGLUR5B | mGlu5glutamate receptor, metabotropic 5-HPRD11953448 
GRM7FLJ40498 | GLUR7 | GPRC1G | MGLUR7 | mGlu7glutamate receptor, metabotropic 7-HPRD10488094 |11953448 
HSP90AA1FLJ31884 | HSP86 | HSP89A | HSP90A | HSP90N | HSPC1 | HSPCA | HSPCAL1 | HSPCAL4 | HSPN | Hsp89 | Hsp90 | LAP2heat shock protein 90kDa alpha (cytosolic), class A member 1-HPRD8486648 
IQGAP1HUMORFA01 | KIAA0051 | SAR1 | p195IQ motif containing GTPase activating protein 1Reconstituted ComplexBioGRID11734550 |12446675 
IQGAP2-IQ motif containing GTPase activating protein 2-HPRD8756646 
KCNN2KCa2.2 | SK2 | SKCA2 | hSK2potassium intermediate/small conductance calcium-activated channel, subfamily N, member 2-HPRD,BioGRID11323678 
KCNQ2BFNC | EBN | EBN1 | ENB1 | HNSPC | KCNA11 | KV7.2 | KVEBN1potassium voltage-gated channel, KQT-like subfamily, member 2-HPRD12032157 
KCNQ5Kv7.5potassium voltage-gated channel, KQT-like subfamily, member 5-HPRD12032157 
LYSTCHS | CHS1lysosomal trafficking regulator-HPRD11984006 
MAPTDDPAC | FLJ31424 | FTDP-17 | MAPTL | MGC138549 | MSTD | MTBT1 | MTBT2 | PPND | TAUmicrotubule-associated protein tau-HPRD,BioGRID2123288 
MYF5bHLHc2myogenic factor 5-HPRD10757985 
MYF6MRF4 | bHLHc4myogenic factor 6 (herculin)-HPRD10757985 
MYLKDKFZp686I10125 | FLJ12216 | KRP | MLCK | MLCK1 | MLCK108 | MLCK210 | MSTP083 | MYLK1 | smMLCKmyosin light chain kinase-HPRD,BioGRID7947686 
MYO9BCELIAC4 | MYR5myosin IXB-HPRD,BioGRID9490638 
MYOD1MYF3 | MYOD | PUM | bHLHc1myogenic differentiation 1-HPRD10757985 
MYOGMYF4 | MYOGENIN | bHLHc3myogenin (myogenic factor 4)-HPRD10757985 
NEUROD1BETA2 | BHF-1 | NEUROD | bHLHa3neurogenic differentiation 1-HPRD10757985 
OPRM1KIAA0403 | MOR | MOR1 | OPRMopioid receptor, mu 1-HPRD,BioGRID11457836 
PCNTKEN | MOPD2 | PCN | PCNT2 | PCNTB | PCTN2 | SCKL4pericentrinReconstituted ComplexBioGRID10823944 
PDE1AHCAM1 | HSPDE1A | MGC26303phosphodiesterase 1A, calmodulin-dependent-HPRD,BioGRID12135876 
PHKG1PHKGphosphorylase kinase, gamma 1 (muscle)-HPRD2507540 
PPEF1PP7 | PPEF | PPP7Cprotein phosphatase, EF-hand calcium binding domain 1-HPRD,BioGRID12051765 
PPEF2-protein phosphatase, EF-hand calcium binding domain 2-HPRD,BioGRID12051765 
PTH2RPTHR2parathyroid hormone 2 receptorCalmodulin interacts with PTH2R.BIND15670850 
RAB3B-RAB3B, member RAS oncogene family-HPRD11741295 
RIT2RIBA | RIN | ROC2Ras-like without CAAX 2-HPRD,BioGRID8824319 
RYR1CCO | MHS | MHS1 | RYDR | RYR | SKRRryanodine receptor 1 (skeletal)-HPRD12509414 
SCN4AHYKPP | HYPP | NAC1A | Na(V)1.4 | Nav1.4 | SkM1sodium channel, voltage-gated, type IV, alpha subunitNav1.4 interacts with CaM. This interaction was modeled on a demonstrated interaction between rat Nav1.4 and human CaM.BIND15746172 
SCTRSRsecretin receptorCalmodulin interacts with SECRR.BIND15670850 
SLC9A1APNH | FLJ42224 | NHE1solute carrier family 9 (sodium/hydrogen exchanger), member 1Far WesternBioGRID12809501 
SNCAMGC110988 | NACP | PARK1 | PARK4 | PD1synuclein, alpha (non A4 component of amyloid precursor)-HPRD,BioGRID12358748 
SNTA1SNT1 | TACIP1 | dJ1187J4.5syntrophin, alpha 1 (dystrophin-associated protein A1, 59kDa, acidic component)-HPRD9512352 
SYT1DKFZp781D2042 | P65 | SVP65 | SYTsynaptotagmin IReconstituted ComplexBioGRID8901523 
TCF3E2A | ITF1 | MGC129647 | MGC129648 | bHLHb21transcription factor 3 (E2A immunoglobulin enhancer binding factors E12/E47)-HPRD,BioGRID10757985 
TCF4E2-2 | ITF2 | MGC149723 | MGC149724 | PTHS | SEF2 | SEF2-1 | SEF2-1A | SEF2-1B | bHLHb19transcription factor 4-HPRD,BioGRID10757985 
TRPV1DKFZp434K0220 | VR1transient receptor potential cation channel, subfamily V, member 1Affinity Capture-Western
Reconstituted Complex
BioGRID12808128 
TTNCMD1G | CMH9 | CMPD4 | CONNECTIN | DKFZp451N061 | EOMFC | FLJ26020 | FLJ26409 | FLJ32040 | FLJ34413 | FLJ39564 | FLJ43066 | HMERF | LGMD2J | TMDtitin-HPRD11178895 
VIPR1FLJ41949 | HVR1 | II | PACAP-R-2 | RDC1 | VAPC1 | VIPR | VIRG | VPAC1 | VPCAP1Rvasoactive intestinal peptide receptor 1Calmodulin interacts with VIP1R.BIND15670850 
YWHAE14-3-3E | FLJ45465 | KCIP-1 | MDCR | MDStyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide-HPRD10088721 


Section V. Pathway annotation

Pathway namePathway size# SZGR 2.0 genes in pathwayInfo
KEGG CALCIUM SIGNALING PATHWAY 178134All SZGR 2.0 genes in this pathway
KEGG PHOSPHATIDYLINOSITOL SIGNALING SYSTEM 7656All SZGR 2.0 genes in this pathway
KEGG OOCYTE MEIOSIS 11479All SZGR 2.0 genes in this pathway
KEGG VASCULAR SMOOTH MUSCLE CONTRACTION 11581All SZGR 2.0 genes in this pathway
KEGG LONG TERM POTENTIATION 7057All SZGR 2.0 genes in this pathway
KEGG NEUROTROPHIN SIGNALING PATHWAY 126103All SZGR 2.0 genes in this pathway
KEGG OLFACTORY TRANSDUCTION 38985All SZGR 2.0 genes in this pathway
KEGG INSULIN SIGNALING PATHWAY 137103All SZGR 2.0 genes in this pathway
KEGG GNRH SIGNALING PATHWAY 10177All SZGR 2.0 genes in this pathway
KEGG MELANOGENESIS 10280All SZGR 2.0 genes in this pathway
KEGG ALZHEIMERS DISEASE 169110All SZGR 2.0 genes in this pathway
KEGG GLIOMA 6556All SZGR 2.0 genes in this pathway
BIOCARTA NO1 PATHWAY 3324All SZGR 2.0 genes in this pathway
BIOCARTA AT1R PATHWAY 3628All SZGR 2.0 genes in this pathway
BIOCARTA BCR PATHWAY 3728All SZGR 2.0 genes in this pathway
BIOCARTA BIOPEPTIDES PATHWAY 4535All SZGR 2.0 genes in this pathway
BIOCARTA CACAM PATHWAY 1611All SZGR 2.0 genes in this pathway
BIOCARTA HDAC PATHWAY 3225All SZGR 2.0 genes in this pathway
BIOCARTA GCR PATHWAY 2217All SZGR 2.0 genes in this pathway
BIOCARTA CALCINEURIN PATHWAY 2117All SZGR 2.0 genes in this pathway
BIOCARTA NDKDYNAMIN PATHWAY 2115All SZGR 2.0 genes in this pathway
BIOCARTA FCER1 PATHWAY 4130All SZGR 2.0 genes in this pathway
BIOCARTA FMLP PATHWAY 3929All SZGR 2.0 genes in this pathway
BIOCARTA PYK2 PATHWAY 3124All SZGR 2.0 genes in this pathway
BIOCARTA VIP PATHWAY 2926All SZGR 2.0 genes in this pathway
BIOCARTA NFAT PATHWAY 5645All SZGR 2.0 genes in this pathway
BIOCARTA NOS1 PATHWAY 2421All SZGR 2.0 genes in this pathway
BIOCARTA CCR5 PATHWAY 2016All SZGR 2.0 genes in this pathway
BIOCARTA PGC1A PATHWAY 2620All SZGR 2.0 genes in this pathway
BIOCARTA MEF2D PATHWAY 2316All SZGR 2.0 genes in this pathway
BIOCARTA GPCR PATHWAY 3731All SZGR 2.0 genes in this pathway
BIOCARTA TCR PATHWAY 4937All SZGR 2.0 genes in this pathway
REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS 1810All SZGR 2.0 genes in this pathway
REACTOME SIGNALLING BY NGF 217167All SZGR 2.0 genes in this pathway
REACTOME DAG AND IP3 SIGNALING 3225All SZGR 2.0 genes in this pathway
REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION 139All SZGR 2.0 genes in this pathway
REACTOME SIGNALING BY ERBB2 10178All SZGR 2.0 genes in this pathway
REACTOME SIGNALING BY EGFR IN CANCER 10980All SZGR 2.0 genes in this pathway
REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS 2924All SZGR 2.0 genes in this pathway
REACTOME SIGNALING BY THE B CELL RECEPTOR BCR 12690All SZGR 2.0 genes in this pathway
REACTOME NGF SIGNALLING VIA TRKA FROM THE PLASMA MEMBRANE 137105All SZGR 2.0 genes in this pathway
REACTOME SIGNALING BY FGFR IN DISEASE 12788All SZGR 2.0 genes in this pathway
REACTOME ENOS ACTIVATION AND REGULATION 2014All SZGR 2.0 genes in this pathway
REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 8956All SZGR 2.0 genes in this pathway
REACTOME TRANSMISSION ACROSS CHEMICAL SYNAPSES 186155All SZGR 2.0 genes in this pathway
REACTOME NEURONAL SYSTEM 279221All SZGR 2.0 genes in this pathway
REACTOME SIGNALING BY GPCR 920449All SZGR 2.0 genes in this pathway
REACTOME OPIOID SIGNALLING 7856All SZGR 2.0 genes in this pathway
REACTOME CA DEPENDENT EVENTS 3023All SZGR 2.0 genes in this pathway
REACTOME DARPP 32 EVENTS 2520All SZGR 2.0 genes in this pathway
REACTOME NEUROTRANSMITTER RECEPTOR BINDING AND DOWNSTREAM TRANSMISSION IN THE POSTSYNAPTIC CELL 137110All SZGR 2.0 genes in this pathway
REACTOME PLC BETA MEDIATED EVENTS 4332All SZGR 2.0 genes in this pathway
REACTOME SIGNALING BY PDGF 12293All SZGR 2.0 genes in this pathway
REACTOME DOWNSTREAM SIGNAL TRANSDUCTION 9576All SZGR 2.0 genes in this pathway
REACTOME MUSCLE CONTRACTION 4824All SZGR 2.0 genes in this pathway
REACTOME RAS ACTIVATION UOPN CA2 INFUX THROUGH NMDA RECEPTOR 1715All SZGR 2.0 genes in this pathway
REACTOME SMOOTH MUSCLE CONTRACTION 2514All SZGR 2.0 genes in this pathway
REACTOME ACTIVATION OF NMDA RECEPTOR UPON GLUTAMATE BINDING AND POSTSYNAPTIC EVENTS 3732All SZGR 2.0 genes in this pathway
REACTOME CREB PHOSPHORYLATION THROUGH THE ACTIVATION OF RAS 2723All SZGR 2.0 genes in this pathway
REACTOME POST NMDA RECEPTOR ACTIVATION EVENTS 3328All SZGR 2.0 genes in this pathway
REACTOME CREB PHOSPHORYLATION THROUGH THE ACTIVATION OF CAMKII 1514All SZGR 2.0 genes in this pathway
REACTOME DOWNSTREAM SIGNALING OF ACTIVATED FGFR 10074All SZGR 2.0 genes in this pathway
REACTOME PHOSPHOLIPASE C MEDIATED CASCADE 5440All SZGR 2.0 genes in this pathway
REACTOME ACTIVATION OF KAINATE RECEPTORS UPON GLUTAMATE BINDING 3123All SZGR 2.0 genes in this pathway
REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS 1111All SZGR 2.0 genes in this pathway
REACTOME METABOLISM OF CARBOHYDRATES 247154All SZGR 2.0 genes in this pathway
REACTOME HEMOSTASIS 466331All SZGR 2.0 genes in this pathway
REACTOME IMMUNE SYSTEM 933616All SZGR 2.0 genes in this pathway
REACTOME GLUCOSE METABOLISM 6942All SZGR 2.0 genes in this pathway
REACTOME ADAPTIVE IMMUNE SYSTEM 539350All SZGR 2.0 genes in this pathway
REACTOME PLATELET ACTIVATION SIGNALING AND AGGREGATION 208138All SZGR 2.0 genes in this pathway
REACTOME SIGNALING BY FGFR 11280All SZGR 2.0 genes in this pathway
ONKEN UVEAL MELANOMA UP 783507All SZGR 2.0 genes in this pathway
FULCHER INFLAMMATORY RESPONSE LECTIN VS LPS UP 579346All SZGR 2.0 genes in this pathway
PUIFFE INVASION INHIBITED BY ASCITES UP 8251All SZGR 2.0 genes in this pathway
DIAZ CHRONIC MEYLOGENOUS LEUKEMIA UP 1382904All SZGR 2.0 genes in this pathway
DEURIG T CELL PROLYMPHOCYTIC LEUKEMIA DN 320184All SZGR 2.0 genes in this pathway
RHEIN ALL GLUCOCORTICOID THERAPY DN 362238All SZGR 2.0 genes in this pathway
MULLIGHAN MLL SIGNATURE 1 UP 380236All SZGR 2.0 genes in this pathway
TIEN INTESTINE PROBIOTICS 24HR UP 557331All SZGR 2.0 genes in this pathway
KINSEY TARGETS OF EWSR1 FLII FUSION UP 1278748All SZGR 2.0 genes in this pathway
ELVIDGE HYPOXIA DN 14694All SZGR 2.0 genes in this pathway
ELVIDGE HYPOXIA BY DMOG DN 5940All SZGR 2.0 genes in this pathway
DODD NASOPHARYNGEAL CARCINOMA UP 1821933All SZGR 2.0 genes in this pathway
RODRIGUES THYROID CARCINOMA ANAPLASTIC DN 537339All SZGR 2.0 genes in this pathway
HAHTOLA MYCOSIS FUNGOIDES SKIN UP 177113All SZGR 2.0 genes in this pathway
HAHTOLA MYCOSIS FUNGOIDES CD4 DN 11671All SZGR 2.0 genes in this pathway
KOKKINAKIS METHIONINE DEPRIVATION 48HR DN 6439All SZGR 2.0 genes in this pathway
KOKKINAKIS METHIONINE DEPRIVATION 96HR DN 7550All SZGR 2.0 genes in this pathway
LINDGREN BLADDER CANCER CLUSTER 2B 392251All SZGR 2.0 genes in this pathway
SCHLOSSER SERUM RESPONSE DN 712443All SZGR 2.0 genes in this pathway
WEINMANN ADAPTATION TO HYPOXIA UP 2924All SZGR 2.0 genes in this pathway
MOHANKUMAR TLX1 TARGETS UP 414287All SZGR 2.0 genes in this pathway
JOHANSSON BRAIN CANCER EARLY VS LATE DN 4535All SZGR 2.0 genes in this pathway
TOMLINS PROSTATE CANCER DN 4033All SZGR 2.0 genes in this pathway
SPIELMAN LYMPHOBLAST EUROPEAN VS ASIAN UP 479299All SZGR 2.0 genes in this pathway
LOCKWOOD AMPLIFIED IN LUNG CANCER 214139All SZGR 2.0 genes in this pathway
WEI MYCN TARGETS WITH E BOX 795478All SZGR 2.0 genes in this pathway
RICKMAN TUMOR DIFFERENTIATED WELL VS POORLY DN 382224All SZGR 2.0 genes in this pathway
SCHAEFFER PROSTATE DEVELOPMENT 48HR UP 487286All SZGR 2.0 genes in this pathway
ONDER CDH1 TARGETS 1 DN 169102All SZGR 2.0 genes in this pathway
PARK HSC VS MULTIPOTENT PROGENITORS DN 1812All SZGR 2.0 genes in this pathway
KUROKAWA LIVER CANCER CHEMOTHERAPY DN 4128All SZGR 2.0 genes in this pathway
IIZUKA LIVER CANCER PROGRESSION L1 G1 UP 2515All SZGR 2.0 genes in this pathway
PENG GLUCOSE DEPRIVATION DN 169112All SZGR 2.0 genes in this pathway
FLECHNER BIOPSY KIDNEY TRANSPLANT REJECTED VS OK DN 546351All SZGR 2.0 genes in this pathway
NING CHRONIC OBSTRUCTIVE PULMONARY DISEASE UP 157105All SZGR 2.0 genes in this pathway
HADDAD B LYMPHOCYTE PROGENITOR 293193All SZGR 2.0 genes in this pathway
THEILGAARD NEUTROPHIL AT SKIN WOUND DN 225163All SZGR 2.0 genes in this pathway
YAGI AML SURVIVAL 12987All SZGR 2.0 genes in this pathway
FAELT B CLL WITH VH3 21 DN 4929All SZGR 2.0 genes in this pathway
LU AGING BRAIN DN 153120All SZGR 2.0 genes in this pathway
BLALOCK ALZHEIMERS DISEASE DN 1237837All SZGR 2.0 genes in this pathway
CUI TCF21 TARGETS 2 DN 830547All SZGR 2.0 genes in this pathway
YAMAZAKI TCEB3 TARGETS UP 175116All SZGR 2.0 genes in this pathway
BROWNE HCMV INFECTION 8HR UP 10573All SZGR 2.0 genes in this pathway
HELLER HDAC TARGETS SILENCED BY METHYLATION UP 461298All SZGR 2.0 genes in this pathway
ACEVEDO LIVER CANCER DN 540340All SZGR 2.0 genes in this pathway
BERNARD PPAPDC1B TARGETS DN 5839All SZGR 2.0 genes in this pathway
HUANG DASATINIB RESISTANCE DN 6944All SZGR 2.0 genes in this pathway
FOURNIER ACINAR DEVELOPMENT LATE 2 277172All SZGR 2.0 genes in this pathway
YAO TEMPORAL RESPONSE TO PROGESTERONE CLUSTER 17 181101All SZGR 2.0 genes in this pathway
STAMBOLSKY TARGETS OF MUTATED TP53 UP 4935All SZGR 2.0 genes in this pathway
KIM ALL DISORDERS CALB1 CORR UP 548370All SZGR 2.0 genes in this pathway
VERHAAK GLIOBLASTOMA CLASSICAL 162122All SZGR 2.0 genes in this pathway
GREGORY SYNTHETIC LETHAL WITH IMATINIB 14583All SZGR 2.0 genes in this pathway
THILLAINADESAN ZNF217 TARGETS UP 4422All SZGR 2.0 genes in this pathway
PILON KLF1 TARGETS DN 19721213All SZGR 2.0 genes in this pathway
BHAT ESR1 TARGETS VIA AKT1 UP 281183All SZGR 2.0 genes in this pathway
JOHNSTONE PARVB TARGETS 3 UP 430288All SZGR 2.0 genes in this pathway
IKEDA MIR30 TARGETS UP 11687All SZGR 2.0 genes in this pathway
WAKABAYASHI ADIPOGENESIS PPARG BOUND 8D 658397All SZGR 2.0 genes in this pathway
KRIEG HYPOXIA NOT VIA KDM3A 770480All SZGR 2.0 genes in this pathway
FORTSCHEGGER PHF8 TARGETS DN 784464All SZGR 2.0 genes in this pathway
PECE MAMMARY STEM CELL DN 14688All SZGR 2.0 genes in this pathway

Section VI. microRNA annotation

miRNA familyTarget positionmiRNA IDmiRNA seq
UTR startUTR endMatch method
let-7/984724781Ahsa-let-7abrainUGAGGUAGUAGGUUGUAUAGUU
hsa-let-7bbrainUGAGGUAGUAGGUUGUGUGGUU
hsa-let-7cbrainUGAGGUAGUAGGUUGUAUGGUU
hsa-let-7dbrainAGAGGUAGUAGGUUGCAUAGU
hsa-let-7ebrainUGAGGUAGGAGGUUGUAUAGU
hsa-let-7fbrainUGAGGUAGUAGAUUGUAUAGUU
hsa-miR-98brainUGAGGUAGUAAGUUGUAUUGUU
hsa-let-7gSZUGAGGUAGUAGUUUGUACAGU
hsa-let-7ibrainUGAGGUAGUAGUUUGUGCUGU
miR-1/2068308361Ahsa-miR-1UGGAAUGUAAAGAAGUAUGUA
hsa-miR-206SZUGGAAUGUAAGGAAGUGUGUGG
hsa-miR-613AGGAAUGUUCCUUCUUUGCC
miR-129-5p67741A,m8hsa-miR-129brainCUUUUUGCGGUCUGGGCUUGC
hsa-miR-129-5pCUUUUUGCGGUCUGGGCUUGCU
miR-133346334701A,m8hsa-miR-133aUUGGUCCCCUUCAACCAGCUGU
hsa-miR-133bUUGGUCCCCUUCAACCAGCUA
miR-142-3p13671373m8hsa-miR-142-3pUGUAGUGUUUCCUACUUUAUGGA
miR-142-5p290029061Ahsa-miR-142-5pCAUAAAGUAGAAAGCACUAC
miR-14335423548m8hsa-miR-143brainUGAGAUGAAGCACUGUAGCUCA
miR-15/16/195/424/49712281234m8hsa-miR-15abrainUAGCAGCACAUAAUGGUUUGUG
hsa-miR-16brainUAGCAGCACGUAAAUAUUGGCG
hsa-miR-15bbrainUAGCAGCACAUCAUGGUUUACA
hsa-miR-195SZUAGCAGCACAGAAAUAUUGGC
hsa-miR-424CAGCAGCAAUUCAUGUUUUGAA
hsa-miR-497CAGCAGCACACUGUGGUUUGU
miR-181126132m8hsa-miR-181abrainAACAUUCAACGCUGUCGGUGAGU
hsa-miR-181bSZAACAUUCAUUGCUGUCGGUGGG
hsa-miR-181cbrainAACAUUCAACCUGUCGGUGAGU
hsa-miR-181dbrainAACAUUCAUUGUUGUCGGUGGGUU
miR-19282428311A,m8hsa-miR-19aUGUGCAAAUCUAUGCAAAACUGA
hsa-miR-19bUGUGCAAAUCCAUGCAAAACUGA
miR-193301307m8hsa-miR-193aAACUGGCCUACAAAGUCCCAG
hsa-miR-193bAACUGGCCCUCAAAGUCCCGCUUU
miR-196237243m8hsa-miR-196aUAGGUAGUUUCAUGUUGUUGG
hsa-miR-196bUAGGUAGUUUCCUGUUGUUGG
miR-203.135263532m8hsa-miR-203UGAAAUGUUUAGGACCACUAG
miR-214123012361Ahsa-miR-214brainACAGCAGGCACAGACAGGCAG
hsa-miR-214brainACAGCAGGCACAGACAGGCAG
miR-409-5p155215581Ahsa-miR-409-5pAGGUUACCCGAGCAACUUUGCA
miR-410261126171Ahsa-miR-410AAUAUAACACAGAUGGCCUGU