Gene Page: ADGRV1

Summary ?
GeneID84059
SymbolADGRV1
SynonymsFEB4|GPR98|MASS1|USH2B|USH2C|VLGR1|VLGR1b
Descriptionadhesion G protein-coupled receptor V1
ReferenceMIM:602851|HGNC:HGNC:17416|Ensembl:ENSG00000164199|HPRD:09111|Vega:OTTHUMG00000162668
Gene typeprotein-coding
Map location5q13

Gene in Data Sources
Gene set name Method of gene setDescriptionInfo
CV:GWASdbGenome-wide Association StudiesGWASdb records for schizophrenia
CV:PGCnpGenome-wide Association StudyGWAS
DNM:McCarthy_2014Whole Exome Sequencing analysisWhole exome sequencing of 57 trios with sporadic or familial schizophrenia.

Section I. Genetics and epigenetics annotation

@eQTL annotation

SNP IDChromosomePositioneGeneGene Entrez IDpvalueqvalueTSS distanceeQTL type
rs4916794chr589573927GPR98840590.12cis

Section II. Transcriptome annotation

General gene expression (GTEx)

Not available

Gene expression of temporal and spatial changes (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes the lower 25% and upper 25% of the expression distribution.

No co-expressed genes in brain regions


Section III. Gene Ontology annotation

Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0004872receptor activityIEA-
GO:0004930G-protein coupled receptor activityNAS11606593 
GO:0005509calcium ion bindingIDA10976914 
GO:0005515protein bindingIPI16434480 
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0007218neuropeptide signaling pathwayIEANeurotransmitter (GO term level: 8)-
GO:0007399nervous system developmentNASneurite (GO term level: 5)11606593 
GO:0007165signal transductionIEA-
GO:0007605sensory perception of soundIMP14740321 
GO:0016337cell-cell adhesionNAS11606593 
GO:0050896response to stimulusIEA-
GO:0050877neurological system processIMP12402266 
GO:0045494photoreceptor cell maintenanceIMP14740321 
GO:0048496maintenance of organ identityIMP15671307 
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0005737cytoplasmIDA16434480 
GO:0016021integral to membraneIEA-
GO:0009986cell surfaceIDA10976914 
GO:0005886plasma membraneIEA-