Gene Page: MYST1

Summary
GeneID  84148
Symbol  MYST1
Synonyms  FLJ14040|KAT8|MOF|hMOF
Description  MYST histone acetyltransferase 1
See related  HGNC:17933|MIM:609912|Ensembl:ENSG00000103510|HPRD:11381|
Locus tag  -
Gene type  protein-coding
Map location  16p11.2
 
Gene in Data Sources
Gene set name Method of gene set Evidence Info
GSMA_IIEgenome scan meta-analysis (European-ancestry samples)Psr: 0.01775 
 
General Gene Expression (microarray) ?
 
Gene Expression in Brain Regions (new)
 
Top co-expressed genes in Brain Regions (new)
GenePearson's Correlation Spearman's Correlation
Top 10 positively co-expressed genes
Top 10 negatively co-expressed genes
Gene Ontology
Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0003682chromatin bindingIEA-
GO:0004402histone acetyltransferase activityIDA11742995 
GO:0016740transferase activityIEA-
GO:0008270zinc ion bindingIEA-
GO:0008134transcription factor bindingIDA11742995 |11965546 
GO:0016407acetyltransferase activityIDA11742995 
GO:0046872metal ion bindingIEA-
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0006333chromatin assembly or disassemblyIEA-
GO:0006355regulation of transcription, DNA-dependentIEA-
GO:0030099myeloid cell differentiationIDA11742995 
GO:0016568chromatin modificationIEA-
GO:0016481negative regulation of transcriptionIDA11742995 
GO:0016573histone acetylationIDA11742995 
GO:0045941positive regulation of transcriptionIDA11742995 |11965546 
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0000776kinetochoreIEA-
GO:0000785chromatinIEA-
GO:0005634nucleusIDA11742995 
 
InteractionsShown by Network
InteractorsAliases BOfficial full name BExperimentalSourcePubMed ID
MLLALL-1 | CXXC7 | FLJ11783 | HRX | HTRX1 | KMT2A | MLL/GAS7 | MLL1A | TET1-MLL | TRX1myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila)MOF interacts with MLL.BIND15960975 
MORF4L1Eaf3 | FWP006 | HsT17725 | MGC10631 | MORFRG15 | MRG15 | S863-6mortality factor 4 like 1Affinity Capture-Western
Co-purification		BioGRID12397079 
RNF2BAP-1 | BAP1 | DING | HIPI3 | RING1B | RING2ring finger protein 2Ring2 interacts with MOF.BIND15960975 
 
Pathway annotation
Pathway namePathway size# SZGR genes in pathwayInfo
PID_P53_REGULATION_PATHWAY 5950All SZGR genes in this pathway
ZHONG_RESPONSE_TO_AZACITIDINE_AND_TSA_DN 7038All SZGR genes in this pathway
GARY_CD5_TARGETS_UP 473314All SZGR genes in this pathway
GINESTIER_BREAST_CANCER_ZNF217_AMPLIFIED_DN 335193All SZGR genes in this pathway
RICKMAN_METASTASIS_UP 344180All SZGR genes in this pathway
WANG_PROSTATE_CANCER_ANDROGEN_INDEPENDENT 6637All SZGR genes in this pathway
PENG_GLUTAMINE_DEPRIVATION_DN 337230All SZGR genes in this pathway
JI_RESPONSE_TO_FSH_UP 7456All SZGR genes in this pathway
MONNIER_POSTRADIATION_TUMOR_ESCAPE_DN 373196All SZGR genes in this pathway
BROWNE_HCMV_INFECTION_1HR_DN 222147All SZGR genes in this pathway
BROWNE_HCMV_INFECTION_4HR_DN 254158All SZGR genes in this pathway
RATTENBACHER_BOUND_BY_CELF1 467251All SZGR genes in this pathway


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