Gene Page: ELMOD3
Summary ?
| GeneID | 84173 |
| Symbol | ELMOD3 |
| Synonyms | DFNB88|LST3|RBED1|RBM29 |
| Description | ELMO domain containing 3 |
| Reference | MIM:615427|HGNC:HGNC:26158|Ensembl:ENSG00000115459|HPRD:07973|Vega:OTTHUMG00000130170 |
| Gene type | protein-coding |
| Map location | 2p11.2 |
| Pascal p-value | 0.015 |
| Sherlock p-value | 0.845 |
| eGene | Myers' cis & trans |
Gene in Data Sources
| Gene set name | Method of gene set | Description | Info |
|---|---|---|---|
| CV:PGCnp | Genome-wide Association Study | GWAS |
Section I. Genetics and epigenetics annotation
eQTL annotation
| SNP ID | Chromosome | Position | eGene | Gene Entrez ID | pvalue | qvalue | TSS distance | eQTL type |
|---|---|---|---|---|---|---|---|---|
| rs1146358 | chr1 | 116657767 | ELMOD3 | 84173 | 0.03 | trans | ||
| rs16854815 | chr1 | 204931605 | ELMOD3 | 84173 | 0.09 | trans | ||
| rs1934577 | chr1 | 246016542 | ELMOD3 | 84173 | 0.11 | trans | ||
| rs2716734 | chr2 | 39947720 | ELMOD3 | 84173 | 7.757E-6 | trans | ||
| rs2716736 | chr2 | 39947946 | ELMOD3 | 84173 | 7.757E-6 | trans | ||
| rs6754175 | chr2 | 135333296 | ELMOD3 | 84173 | 0.01 | trans | ||
| rs11928084 | chr3 | 4138812 | ELMOD3 | 84173 | 0.09 | trans | ||
| rs16850133 | chr3 | 140030776 | ELMOD3 | 84173 | 0 | trans | ||
| rs7638929 | chr3 | 140031075 | ELMOD3 | 84173 | 0.06 | trans | ||
| rs2597796 | chr4 | 17535859 | ELMOD3 | 84173 | 0.19 | trans | ||
| rs467856 | chr5 | 3128168 | ELMOD3 | 84173 | 0.09 | trans | ||
| rs9637832 | chr5 | 15757838 | ELMOD3 | 84173 | 0.18 | trans | ||
| snp_a-2169623 | 0 | ELMOD3 | 84173 | 4.35E-6 | trans | |||
| rs6873234 | chr5 | 169299967 | ELMOD3 | 84173 | 0.01 | trans | ||
| rs7383548 | 0 | ELMOD3 | 84173 | 0.04 | trans | |||
| rs2016128 | chr6 | 42442743 | ELMOD3 | 84173 | 0.15 | trans | ||
| rs1587434 | chr6 | 66615354 | ELMOD3 | 84173 | 2.405E-8 | trans | ||
| rs4947631 | chr7 | 50603378 | ELMOD3 | 84173 | 0.1 | trans | ||
| rs10257132 | chr7 | 51422943 | ELMOD3 | 84173 | 0.15 | trans | ||
| rs529539 | chr7 | 84003500 | ELMOD3 | 84173 | 0.01 | trans | ||
| rs870686 | chr8 | 25253521 | ELMOD3 | 84173 | 0.15 | trans | ||
| rs10503771 | chr8 | 25304019 | ELMOD3 | 84173 | 0.03 | trans | ||
| rs10994470 | chr10 | 51558659 | ELMOD3 | 84173 | 0.09 | trans | ||
| rs1935471 | chr10 | 56120565 | ELMOD3 | 84173 | 0.2 | trans | ||
| rs12767540 | chr10 | 56171628 | ELMOD3 | 84173 | 0.12 | trans | ||
| rs17106311 | chr10 | 87897271 | ELMOD3 | 84173 | 0.14 | trans | ||
| rs17107175 | chr10 | 88646323 | ELMOD3 | 84173 | 0.09 | trans | ||
| rs1539587 | chr10 | 115372155 | ELMOD3 | 84173 | 0.08 | trans | ||
| rs7129903 | chr11 | 7775320 | ELMOD3 | 84173 | 0.09 | trans | ||
| rs4944475 | chr11 | 83985410 | ELMOD3 | 84173 | 0.18 | trans | ||
| rs11183748 | chr12 | 47516125 | ELMOD3 | 84173 | 0.05 | trans | ||
| rs12423193 | chr12 | 63753383 | ELMOD3 | 84173 | 0.01 | trans | ||
| rs9888446 | chr12 | 63785677 | ELMOD3 | 84173 | 0 | trans | ||
| rs1400878 | chr12 | 83609397 | ELMOD3 | 84173 | 0.12 | trans | ||
| rs16945217 | chr12 | 115679171 | ELMOD3 | 84173 | 0.09 | trans | ||
| rs998923 | chr13 | 35507810 | ELMOD3 | 84173 | 0.02 | trans | ||
| rs2764585 | chr13 | 46880234 | ELMOD3 | 84173 | 0.09 | trans | ||
| rs9590075 | chr13 | 95414389 | ELMOD3 | 84173 | 0.09 | trans | ||
| snp_a-2222355 | 0 | ELMOD3 | 84173 | 0 | trans | |||
| rs6495316 | chr15 | 78986100 | ELMOD3 | 84173 | 0.02 | trans | ||
| rs1461211 | chr15 | 88628773 | ELMOD3 | 84173 | 0.18 | trans | ||
| rs12596294 | chr16 | 72587092 | ELMOD3 | 84173 | 0.19 | trans | ||
| rs4792093 | chr17 | 10939374 | ELMOD3 | 84173 | 0.08 | trans | ||
| rs7223509 | chr17 | 10940048 | ELMOD3 | 84173 | 0.08 | trans | ||
| rs1015663 | chr17 | 14238086 | ELMOD3 | 84173 | 0.15 | trans | ||
| rs349973 | chr17 | 50642288 | ELMOD3 | 84173 | 0.13 | trans | ||
| rs8078127 | chr17 | 50761342 | ELMOD3 | 84173 | 0.03 | trans | ||
| rs10512600 | chr17 | 72812978 | ELMOD3 | 84173 | 0.04 | trans | ||
| rs2661679 | chr17 | 76172103 | ELMOD3 | 84173 | 0.12 | trans | ||
| rs7217417 | chr17 | 76173174 | ELMOD3 | 84173 | 0.16 | trans | ||
| rs10521889 | chrX | 149836861 | ELMOD3 | 84173 | 0.03 | trans |
Section II. Transcriptome annotation
General gene expression (GTEx)
Gene expression of temporal and spatial changes (BrainSpan)
Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes the lower 25% and upper 25% of the expression distribution.
No co-expressed genes in brain regions
Section III. Gene Ontology annotation
| Biological process | GO term | Evidence | Neuro keywords | PubMed ID |
|---|---|---|---|---|
| GO:0006909 | phagocytosis | IEA | - | |
| Cellular component | GO term | Evidence | Neuro keywords | PubMed ID |
| GO:0005856 | cytoskeleton | IEA | - |
Section V. Pathway annotation
| Pathway name | Pathway size | # SZGR 2.0 genes in pathway | Info |
|---|---|---|---|
| GERY CEBP TARGETS | 126 | 90 | All SZGR 2.0 genes in this pathway |
| GRADE COLON CANCER UP | 871 | 505 | All SZGR 2.0 genes in this pathway |
| WAKABAYASHI ADIPOGENESIS PPARG RXRA BOUND 36HR | 152 | 88 | All SZGR 2.0 genes in this pathway |
| WAKABAYASHI ADIPOGENESIS PPARG RXRA BOUND 8D | 882 | 506 | All SZGR 2.0 genes in this pathway |
Section VI. microRNA annotation
| miRNA family | Target position | miRNA ID | miRNA seq | ||
|---|---|---|---|---|---|
| UTR start | UTR end | Match method | |||
| miR-138 | 1209 | 1215 | 1A | hsa-miR-138brain | AGCUGGUGUUGUGAAUC |
| miR-204/211 | 335 | 341 | m8 | hsa-miR-204brain | UUCCCUUUGUCAUCCUAUGCCU |
| hsa-miR-211 | UUCCCUUUGUCAUCCUUCGCCU | ||||
- SZ: miRNAs which differentially expressed in brain cortex of schizophrenia patients comparing with control samples using microarray. Click here to see the list of SZ related miRNAs.
- Brain: miRNAs which are expressed in brain based on miRNA microarray expression studies. Click here to see the list of brain related miRNAs.