Gene Page: STC2

Summary
GeneID  8614
Symbol  STC2
Synonyms  STC-2|STCRP
Description  stanniocalcin 2
See related  HGNC:11374|MIM:603665|Ensembl:ENSG00000113739|HPRD:04717|
Locus tag  -
Gene type  protein-coding
Map location  5q35.2
 
Gene in Data Sources
Gene set name Method of gene set Evidence Info
GSMA_IIAgenome scan meta-analysis (All samples)Psr: 0.0276 
 
General Gene Expression (microarray) ?
 
Gene Expression in Brain Regions (new)
 
Top co-expressed genes in Brain Regions (new)
GenePearson's Correlation Spearman's Correlation
Top 10 positively co-expressed genes
THOC40.950.93
RANBP10.930.89
H2AFY0.920.92
SFRS70.920.89
RUVBL10.920.92
HNRNPM0.920.89
C1orf770.910.93
U2AF10.910.90
HNRNPL0.910.91
AC026691.10.910.91
Top 10 negatively co-expressed genes
AF347015.27-0.73-0.87
AF347015.33-0.73-0.87
AF347015.31-0.73-0.85
MT-CO2-0.72-0.85
MT-CYB-0.71-0.85
AF347015.8-0.71-0.86
AF347015.15-0.70-0.87
HLA-F-0.67-0.74
AF347015.2-0.67-0.85
AF347015.26-0.66-0.85
Gene Ontology
Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0005179hormone activityTAS9723890 
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0007267cell-cell signalingTAS9753616 
GO:0007166cell surface receptor linked signal transductionTAS9753616 
GO:0007584response to nutrientTAS9753616 
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0005576extracellular regionIEA-
 
Protein-protein InteractionsShown by network
InteractorsAliases BOfficial full name BExperimentalSourcePubMed ID
ADAM11MDCADAM metallopeptidase domain 11Two-hybridBioGRID16169070 
AIFM1AIF | MGC111425 | PDCD8apoptosis-inducing factor, mitochondrion-associated, 1Two-hybridBioGRID16169070 
ARRB2ARB2 | ARR2 | BARR2 | DKFZp686L0365arrestin, beta 2Two-hybridBioGRID16169070 
CARHSP1CRHSP-24 | CSDC1 | MGC111446calcium regulated heat stable protein 1, 24kDaTwo-hybridBioGRID16169070 
EIF2B3EIF-2B | EIF2Bgammaeukaryotic translation initiation factor 2B, subunit 3 gamma, 58kDaTwo-hybridBioGRID16169070 
FLJ10357SOLOhypothetical protein FLJ10357Two-hybridBioGRID16169070 
PEBP1HCNP | PBP | PEBP | RKIPphosphatidylethanolamine binding protein 1Two-hybridBioGRID16169070 
POLR2CRPB3 | RPB31 | hRPB33 | hsRPB3polymerase (RNA) II (DNA directed) polypeptide C, 33kDaTwo-hybridBioGRID16169070 
POLR3FMGC13517 | RPC39 | RPC6polymerase (RNA) III (DNA directed) polypeptide F, 39 kDaTwo-hybridBioGRID16169070 
PPP1R8ARD-1 | ARD1 | NIPP-1 | NIPP1 | PRO2047protein phosphatase 1, regulatory (inhibitor) subunit 8Two-hybridBioGRID16169070 
PTNHARP | HBGF8 | HBNF | NEGF1pleiotrophinTwo-hybridBioGRID16169070 
 
Pathway annotation
Pathway namePathway size# SZGR genes in pathwayInfo
NAKAMURA_TUMOR_ZONE_PERIPHERAL_VS_CENTRAL_DN 634384All SZGR genes in this pathway
SCHUETZ_BREAST_CANCER_DUCTAL_INVASIVE_DN 8453All SZGR genes in this pathway
IGARASHI_ATF4_TARGETS_DN 9065All SZGR genes in this pathway
DAVICIONI_MOLECULAR_ARMS_VS_ERMS_UP 332228All SZGR genes in this pathway
TURASHVILI_BREAST_LOBULAR_CARCINOMA_VS_DUCTAL_NORMAL_DN 9153All SZGR genes in this pathway
TURASHVILI_BREAST_LOBULAR_CARCINOMA_VS_LOBULAR_NORMAL_UP 9459All SZGR genes in this pathway
PRAMOONJAGO_SOX4_TARGETS_UP 5238All SZGR genes in this pathway
DEURIG_T_CELL_PROLYMPHOCYTIC_LEUKEMIA_UP 368234All SZGR genes in this pathway
DOANE_BREAST_CANCER_ESR1_UP 11272All SZGR genes in this pathway
HORIUCHI_WTAP_TARGETS_UP 306188All SZGR genes in this pathway
VECCHI_GASTRIC_CANCER_ADVANCED_VS_EARLY_UP 175120All SZGR genes in this pathway
OSWALD_HEMATOPOIETIC_STEM_CELL_IN_COLLAGEN_GEL_DN 275168All SZGR genes in this pathway
GARGALOVIC_RESPONSE_TO_OXIDIZED_PHOSPHOLIPIDS_RED_UP 1713All SZGR genes in this pathway
ZHOU_INFLAMMATORY_RESPONSE_LPS_UP 431237All SZGR genes in this pathway
ELVIDGE_HYPOXIA_UP 171112All SZGR genes in this pathway
ELVIDGE_HYPOXIA_BY_DMOG_UP 13085All SZGR genes in this pathway
RODRIGUES_THYROID_CARCINOMA_POORLY_DIFFERENTIATED_UP 633376All SZGR genes in this pathway
RODRIGUES_THYROID_CARCINOMA_ANAPLASTIC_UP 722443All SZGR genes in this pathway
GOZGIT_ESR1_TARGETS_DN 781465All SZGR genes in this pathway
CHEBOTAEV_GR_TARGETS_UP 7762All SZGR genes in this pathway
MCBRYAN_PUBERTAL_BREAST_3_4WK_UP 214144All SZGR genes in this pathway
MCBRYAN_PUBERTAL_BREAST_4_5WK_UP 271175All SZGR genes in this pathway
KAN_RESPONSE_TO_ARSENIC_TRIOXIDE 12380All SZGR genes in this pathway
RASHI_RESPONSE_TO_IONIZING_RADIATION_5 14789All SZGR genes in this pathway
PATIL_LIVER_CANCER 747453All SZGR genes in this pathway
AMUNDSON_RESPONSE_TO_ARSENITE 217143All SZGR genes in this pathway
WEINMANN_ADAPTATION_TO_HYPOXIA_DN 4133All SZGR genes in this pathway
MARTORIATI_MDM4_TARGETS_FETAL_LIVER_UP 227137All SZGR genes in this pathway
WANG_HCP_PROSTATE_CANCER 11169All SZGR genes in this pathway
NUYTTEN_EZH2_TARGETS_UP 1037673All SZGR genes in this pathway
BUYTAERT_PHOTODYNAMIC_THERAPY_STRESS_UP 811508All SZGR genes in this pathway
SCHAEFFER_PROSTATE_DEVELOPMENT_48HR_UP 487286All SZGR genes in this pathway
KOYAMA_SEMA3B_TARGETS_UP 292168All SZGR genes in this pathway
BENPORATH_EED_TARGETS 1062725All SZGR genes in this pathway
BENPORATH_ES_WITH_H3K27ME3 1118744All SZGR genes in this pathway
ONDER_CDH1_TARGETS_2_UP 256159All SZGR genes in this pathway
ONDER_CDH1_TARGETS_1_UP 14085All SZGR genes in this pathway
ONDER_CDH1_TARGETS_3_UP 1711All SZGR genes in this pathway
ONDER_CDH1_SIGNALING_VIA_CTNNB1 8358All SZGR genes in this pathway
MANALO_HYPOXIA_UP 207145All SZGR genes in this pathway
ZHAN_MULTIPLE_MYELOMA_CD1_UP 4529All SZGR genes in this pathway
ZHAN_MULTIPLE_MYELOMA_CD1_VS_CD2_UP 6647All SZGR genes in this pathway
BROWN_MYELOID_CELL_DEVELOPMENT_DN 12986All SZGR genes in this pathway
HALMOS_CEBPA_TARGETS_DN 4626All SZGR genes in this pathway
NGUYEN_NOTCH1_TARGETS_DN 8667All SZGR genes in this pathway
MENSE_HYPOXIA_UP 9871All SZGR genes in this pathway
WANG_SMARCE1_TARGETS_DN 371218All SZGR genes in this pathway
BROWNE_HCMV_INFECTION_14HR_DN 298200All SZGR genes in this pathway
LINDVALL_IMMORTALIZED_BY_TERT_UP 7848All SZGR genes in this pathway
LEONARD_HYPOXIA 4735All SZGR genes in this pathway
JIANG_HYPOXIA_NORMAL 311205All SZGR genes in this pathway
MARIADASON_RESPONSE_TO_CURCUMIN_SULINDAC_5 2317All SZGR genes in this pathway
KRIGE_AMINO_ACID_DEPRIVATION 2920All SZGR genes in this pathway
KRIGE_RESPONSE_TO_TOSEDOSTAT_6HR_UP 953554All SZGR genes in this pathway
KRIGE_RESPONSE_TO_TOSEDOSTAT_24HR_UP 783442All SZGR genes in this pathway
CREIGHTON_ENDOCRINE_THERAPY_RESISTANCE_1 528324All SZGR genes in this pathway
HOWLIN_CITED1_TARGETS_2_DN 1711All SZGR genes in this pathway
MARSON_BOUND_BY_FOXP3_UNSTIMULATED 1229713All SZGR genes in this pathway
RIGGINS_TAMOXIFEN_RESISTANCE_DN 220147All SZGR genes in this pathway
RIGGI_EWING_SARCOMA_PROGENITOR_DN 191123All SZGR genes in this pathway
SMID_BREAST_CANCER_RELAPSE_IN_LIVER_DN 109All SZGR genes in this pathway
SMID_BREAST_CANCER_LUMINAL_A_UP 8452All SZGR genes in this pathway
SMID_BREAST_CANCER_BASAL_DN 701446All SZGR genes in this pathway
BONOME_OVARIAN_CANCER_SURVIVAL_OPTIMAL_DEBULKING 246152All SZGR genes in this pathway
BERNARD_PPAPDC1B_TARGETS_DN 5839All SZGR genes in this pathway
BOQUEST_STEM_CELL_CULTURED_VS_FRESH_UP 425298All SZGR genes in this pathway
CHEN_HOXA5_TARGETS_9HR_UP 223132All SZGR genes in this pathway
BLUM_RESPONSE_TO_SALIRASIB_UP 245159All SZGR genes in this pathway
WINTER_HYPOXIA_METAGENE 242168All SZGR genes in this pathway
BOYLAN_MULTIPLE_MYELOMA_D_CLUSTER_UP 2719All SZGR genes in this pathway
RUIZ_TNC_TARGETS_DN 14279All SZGR genes in this pathway
SHEDDEN_LUNG_CANCER_POOR_SURVIVAL_A6 456285All SZGR genes in this pathway
ZHANG_TLX_TARGETS_60HR_DN 277166All SZGR genes in this pathway
COLINA_TARGETS_OF_4EBP1_AND_4EBP2 356214All SZGR genes in this pathway
MILI_PSEUDOPODIA_HAPTOTAXIS_DN 668419All SZGR genes in this pathway
POOLA_INVASIVE_BREAST_CANCER_DN 13483All SZGR genes in this pathway
LOPEZ_MESOTHELIOMA_SURVIVAL_OVERALL_DN 168All SZGR genes in this pathway
KYNG_NORMAL_AGING_DN 3013All SZGR genes in this pathway
KYNG_WERNER_SYNDROM_DN 2914All SZGR genes in this pathway
DUTERTRE_ESTRADIOL_RESPONSE_6HR_UP 229149All SZGR genes in this pathway
DUTERTRE_ESTRADIOL_RESPONSE_24HR_UP 324193All SZGR genes in this pathway
BHAT_ESR1_TARGETS_NOT_VIA_AKT1_UP 211131All SZGR genes in this pathway
BHAT_ESR1_TARGETS_VIA_AKT1_UP 281183All SZGR genes in this pathway
MIYAGAWA_TARGETS_OF_EWSR1_ETS_FUSIONS_DN 229135All SZGR genes in this pathway
VANDESLUIS_COMMD1_TARGETS_GROUP_2_UP 1512All SZGR genes in this pathway
KASLER_HDAC7_TARGETS_2_DN 3223All SZGR genes in this pathway
PEDERSEN_METASTASIS_BY_ERBB2_ISOFORM_7 403240All SZGR genes in this pathway
PLASARI_TGFB1_SIGNALING_VIA_NFIC_10HR_DN 3025All SZGR genes in this pathway
KRIEG_HYPOXIA_NOT_VIA_KDM3A 770480All SZGR genes in this pathway
FORTSCHEGGER_PHF8_TARGETS_UP 279155All SZGR genes in this pathway
ZWANG_DOWN_BY_2ND_EGF_PULSE 293119All SZGR genes in this pathway
miRNA Targets ?
miRNA familyTarget positionmiRNA IDmiRNA seq
UTR startUTR endMatch method
miR-1/20658651A,m8hsa-miR-1UGGAAUGUAAAGAAGUAUGUA
hsa-miR-206SZUGGAAUGUAAGGAAGUGUGUGG
hsa-miR-613AGGAAUGUUCCUUCUUUGCC
miR-246246311A,m8hsa-miR-24SZUGGCUCAGUUCAGCAGGAACAG
miR-329133139m8hsa-miR-329brainAACACACCUGGUUAACCUCUUU
miR-542-3p92981Ahsa-miR-542-3pUGUGACAGAUUGAUAACUGAAA
  • SZ: miRNAs which differentially expressed in brain cortex of schizophrenia patients comparing with control samples using microarray. Click here to see the list of SZ related miRNAs.
  • Brain: miRNAs which are expressed in brain based on miRNA microarray expression studies. Click here to see the list of brain related miRNAs.


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