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Association Linkage Expression Literature GO_Annotation Gene Network miRNA Targets

Gene Ranking Integration

Association Linkage Expression Literature GO_Annotation Gene Network miRNA Targets Datasets Gene Ranking

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Gene Page: ZRANB2

Summary

GeneID

9406

Symbol

ZRANB2

Synonyms

DKFZp686J1831|DKFZp686N09117|FLJ41119|ZIS|ZIS1|ZIS2|ZNF265

Description

zinc finger, RAN-binding domain containing 2

Locus tag

Gene type

protein-coding

Map location

1p31

Gene in Data Sources

Gene set name

Method of gene set

Evidence

Info

GSMA_IIA

genome scan meta-analysis (All samples)

Psr: 0.02692

General Gene Expression (microarray) ?

Gene Expression in Brain Regions (new)

Top co-expressed genes in Brain Regions (new)

Gene

Pearson's Correlation

Spearman's Correlation

Top 10 positively co-expressed genes

IFI27

0.84

0.88

CST3

0.81

0.88

PLA2G5

0.81

0.88

MT3

0.80

0.89

PLAC9

0.79

0.83

CLDN10

0.79

0.89

METRN

0.78

0.81

AC044839.2

0.78

0.84

FXYD1

0.78

0.87

MYL3

0.78

0.84

Top 10 negatively co-expressed genes

MCM3AP

-0.74

-0.83

RNASEN

-0.74

-0.85

UBE4B

-0.74

-0.81

COPG2

-0.73

-0.85

HEATR5B

-0.73

-0.82

ANKRD17

-0.73

-0.79

PDXDC1

-0.73

-0.81

CSDE1

-0.73

-0.87

C10orf76

-0.73

-0.82

ZKSCAN5

-0.73

-0.84

Gene Ontology

Molecular function

GO term

Evidence

Neuro keywords

PubMed ID

GO:0003700

transcription factor activity

TAS

9931435

GO:0003723

RNA binding

TAS

9931435

GO:0005515

protein binding

IPI

17620599

GO:0008270

zinc ion binding

IEA

GO:0046872

metal ion binding

IEA

Biological process

GO term

Evidence

Neuro keywords

PubMed ID

GO:0006397

mRNA processing

IEA

GO:0008380

RNA splicing

TAS

9931435

Cellular component

GO term

Evidence

Neuro keywords

PubMed ID

GO:0005622

intracellular

IEA

GO:0005634

nucleus

TAS

9931435

Protein-protein Interactions

Shown by network

Interactors	Aliases B	Official full name B	Experimental	Source	PubMed ID
ARRB1	ARB1 \| ARR1	arrestin, beta 1	Affinity Capture-MS	BioGRID	17353931
EP300	KAT3B \| p300	E1A binding protein p300	-	HPRD	11448987
SFRS10	DKFZp686F18120 \| Htra2-beta \| SRFS10 \| TRA2-BETA \| TRA2B \| TRAN2B	splicing factor, arginine/serine-rich 10 (transformer 2 homolog, Drosophila)	Protein-RNA	BioGRID	11448987
SFRS12	DKFZp564B176 \| MGC133045 \| SRrp508 \| SRrp86	splicing factor, arginine/serine-rich 12	-	HPRD	14559993
SFRS2	PR264 \| SC-35 \| SC35 \| SFRS2A \| SRp30b	splicing factor, arginine/serine-rich 2	-	HPRD	11448987
SMN1	BCD541 \| SMA \| SMA1 \| SMA2 \| SMA3 \| SMA4 \| SMA@ \| SMN \| SMNT \| T-BCD541	survival of motor neuron 1, telomeric	-	HPRD	11448987
SNRNP70	RNPU1Z \| RPU1 \| SNRP70 \| U170K \| U1AP \| U1RNP	small nuclear ribonucleoprotein 70kDa (U1)	-	HPRD,BioGRID	11448987
U2AF1	DKFZp313J1712 \| FP793 \| RN \| RNU2AF1 \| U2AF35 \| U2AFBP	U2 small nuclear RNA auxiliary factor 1	-	HPRD,BioGRID	11448987
YY1	DELTA \| INO80S \| NF-E1 \| UCRBP \| YIN-YANG-1	YY1 transcription factor	-	HPRD	11448987

Pathway annotation

Pathway name	Pathway size	# SZGR genes in pathway	Info
NAKAMURA_TUMOR_ZONE_PERIPHERAL_VS_CENTRAL_DN	634	384	All SZGR genes in this pathway
LASTOWSKA_NEUROBLASTOMA_COPY_NUMBER_DN	800	473	All SZGR genes in this pathway
CAFFAREL_RESPONSE_TO_THC_UP	33	20	All SZGR genes in this pathway
CAFFAREL_RESPONSE_TO_THC_24HR_5_DN	59	35	All SZGR genes in this pathway
BENPORATH_CYCLING_GENES	648	385	All SZGR genes in this pathway
CHESLER_BRAIN_HIGHEST_EXPRESSION	40	29	All SZGR genes in this pathway
BYSTRYKH_HEMATOPOIESIS_STEM_CELL_QTL_TRANS	882	572	All SZGR genes in this pathway
ZHANG_BREAST_CANCER_PROGENITORS_UP	425	253	All SZGR genes in this pathway
HAN_SATB1_TARGETS_DN	442	275	All SZGR genes in this pathway
MILI_PSEUDOPODIA_HAPTOTAXIS_UP	518	299	All SZGR genes in this pathway
WHITFIELD_CELL_CYCLE_G1_S	147	76	All SZGR genes in this pathway
BRUINS_UVC_RESPONSE_VIA_TP53_GROUP_D	280	158	All SZGR genes in this pathway

miRNA Targets ?

miRNA family	Target position			miRNA ID	miRNA seq
miRNA family	UTR start	UTR end	Match method	miRNA ID	miRNA seq
miR-124.1	528	534	m8	hsa-miR-124a	UUAAGGCACGCGGUGAAUGCCA
miR-124/506	527	534	1A,m8	hsa-miR-506	UAAGGCACCCUUCUGAGUAGA
miR-124/506	527	534	1A,m8	hsa-miR-124^brain	UAAGGCACGCGGUGAAUGCC
miR-135	179	186	1A,m8	hsa-miR-135a	UAUGGCUUUUUAUUCCUAUGUGA
miR-135	179	186	1A,m8	hsa-miR-135b	UAUGGCUUUUCAUUCCUAUGUG
miR-139	1700	1707	1A,m8	hsa-miR-139^brain	UCUACAGUGCACGUGUCU
miR-19	1447	1453	1A	hsa-miR-19a	UGUGCAAAUCUAUGCAAAACUGA
miR-19	1447	1453	1A	hsa-miR-19b	UGUGCAAAUCCAUGCAAAACUGA
miR-203.1	1681	1687	1A	hsa-miR-203	UGAAAUGUUUAGGACCACUAG
miR-30-5p	1623	1629	1A	hsa-miR-30a-5p	UGUAAACAUCCUCGACUGGAAG
				hsa-miR-30c^brain	UGUAAACAUCCUACACUCUCAGC
				hsa-miR-30d^SZ	UGUAAACAUCCCCGACUGGAAG
				hsa-miR-30b^SZ	UGUAAACAUCCUACACUCAGCU
				hsa-miR-30e-5p	UGUAAACAUCCUUGACUGGA
miR-33	1594	1600	1A	hsa-miR-33	GUGCAUUGUAGUUGCAUUG
miR-33	1594	1600	1A	hsa-miR-33b	GUGCAUUGCUGUUGCAUUGCA
miR-496	1711	1717	1A	hsa-miR-496	AUUACAUGGCCAAUCUC
miR-500	104	110	m8	hsa-miR-500	AUGCACCUGGGCAAGGAUUCUG
miR-539	1046	1053	1A,m8	hsa-miR-539	GGAGAAAUUAUCCUUGGUGUGU

SZ: miRNAs which differentially expressed in brain cortex of schizophrenia patients comparing with control samples using microarray. Click here to see the list of SZ related miRNAs.
Brain: miRNAs which are expressed in brain based on miRNA microarray expression studies. Click here to see the list of brain related miRNAs.