Gene Page: DHX38

Summary ?
GeneID9785
SymbolDHX38
SynonymsDDX38|PRP16|PRPF16
DescriptionDEAH-box helicase 38
ReferenceMIM:605584|HGNC:HGNC:17211|Ensembl:ENSG00000140829|HPRD:05720|Vega:OTTHUMG00000137596
Gene typeprotein-coding
Map location16q22
Pascal p-value0.543
Sherlock p-value0.046
Fetal beta0.773
eGeneMyers' cis & trans
Meta
SupportAscano FMRP targets

Gene in Data Sources
Gene set name Method of gene setDescriptionInfo
CV:PGCnpGenome-wide Association StudyGWAS

Section I. Genetics and epigenetics annotation

@eQTL annotation

SNP IDChromosomePositioneGeneGene Entrez IDpvalueqvalueTSS distanceeQTL type
rs1026400chr2143587823DHX3897850.18trans

Section II. Transcriptome annotation

General gene expression (GTEx)

Not available

Gene expression during devlopment (BrainCloud)

Footnote:
A total of 269 time points ploted, with n=38 fetal samples (x=1:38). Each triangle represents one time point.

Gene expression of temporal and spatial changes (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes the lower 25% and upper 25% of the expression distribution.

Top co-expressed genes in brain regions

Top 10 positively co-expressed genes
GenePearson's Correlation Spearman's Correlation
AC020663.10.910.90
NOLC10.910.90
MSL10.910.90
VPS26B0.900.90
C6orf1680.900.89
KIF3C0.890.91
UBP10.890.89
ATCAY0.890.91
FBXW20.890.89
XPO70.890.90
Top 10 negatively co-expressed genes
GenePearson's Correlation Spearman's Correlation
AF347015.31-0.81-0.80
MT-CO2-0.80-0.79
AF347015.21-0.79-0.82
AF347015.8-0.78-0.78
AF347015.27-0.77-0.79
MT-CYB-0.77-0.76
FXYD1-0.77-0.77
AF347015.33-0.76-0.74
HIGD1B-0.75-0.75
AF347015.2-0.75-0.73

Section V. Pathway annotation

Pathway namePathway size# SZGR 2.0 genes in pathwayInfo
KEGG SPLICEOSOME 12872All SZGR 2.0 genes in this pathway
REACTOME PROCESSING OF CAPPED INTRON CONTAINING PRE MRNA 14077All SZGR 2.0 genes in this pathway
REACTOME TRANSPORT OF MATURE TRANSCRIPT TO CYTOPLASM 5434All SZGR 2.0 genes in this pathway
REACTOME RNA POL II TRANSCRIPTION 10554All SZGR 2.0 genes in this pathway
REACTOME MRNA PROCESSING 16186All SZGR 2.0 genes in this pathway
REACTOME MRNA SPLICING 11158All SZGR 2.0 genes in this pathway
REACTOME TRANSCRIPTION 210127All SZGR 2.0 genes in this pathway
REACTOME MRNA 3 END PROCESSING 3518All SZGR 2.0 genes in this pathway
REACTOME CLEAVAGE OF GROWING TRANSCRIPT IN THE TERMINATION REGION 4422All SZGR 2.0 genes in this pathway
BENPORATH NANOG TARGETS 988594All SZGR 2.0 genes in this pathway
BENPORATH SOX2 TARGETS 734436All SZGR 2.0 genes in this pathway
LEE AGING CEREBELLUM DN 8666All SZGR 2.0 genes in this pathway
BROWNE HCMV INFECTION 48HR UP 180125All SZGR 2.0 genes in this pathway
SESTO RESPONSE TO UV C0 10772All SZGR 2.0 genes in this pathway
KAYO CALORIE RESTRICTION MUSCLE UP 9564All SZGR 2.0 genes in this pathway
MARSON BOUND BY FOXP3 UNSTIMULATED 1229713All SZGR 2.0 genes in this pathway
BOCHKIS FOXA2 TARGETS 425261All SZGR 2.0 genes in this pathway
JIANG TIP30 TARGETS DN 2414All SZGR 2.0 genes in this pathway
BOYLAN MULTIPLE MYELOMA C UP 4729All SZGR 2.0 genes in this pathway
YAGI AML WITH INV 16 TRANSLOCATION 422277All SZGR 2.0 genes in this pathway