Gene Page: GATB
Summary ?
| GeneID | 5188 |
| Symbol | GATB |
| Synonyms | HSPC199|PET112|PET112L |
| Description | glutamyl-tRNA(Gln) amidotransferase, subunit B |
| Reference | MIM:603645|HGNC:HGNC:8849|Ensembl:ENSG00000059691|HPRD:04706|Vega:OTTHUMG00000161672 |
| Gene type | protein-coding |
| Map location | 4q31.3 |
Gene in Data Sources
| Gene set name | Method of gene set | Description | Info |
|---|---|---|---|
| CV:PGCnp | Genome-wide Association Study | GWAS | |
| PMID:cooccur | High-throughput literature-search | Systematic search in PubMed for genes co-occurring with SCZ keywords. A total of 3027 genes were included. | |
| Literature | High-throughput literature-search | Co-occurance with Schizophrenia keywords: schizophrenia,schizophrenic,schizophrenias | Click to show details |
Section I. Genetics and epigenetics annotation
Section II. Transcriptome annotation
General gene expression (GTEx)
Gene expression of temporal and spatial changes (BrainSpan)
Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes the lower 25% and upper 25% of the expression distribution.
No co-expressed genes in brain regions
Section III. Gene Ontology annotation
| Molecular function | GO term | Evidence | Neuro keywords | PubMed ID |
|---|---|---|---|---|
| GO:0016884 | carbon-nitrogen ligase activity, with glutamine as amido-N-donor | IEA | glutamate (GO term level: 5) | - |
| GO:0016874 | ligase activity | IEA | - | |
| GO:0008135 | translation factor activity, nucleic acid binding | TAS | 9878253 | |
| Biological process | GO term | Evidence | Neuro keywords | PubMed ID |
| GO:0006412 | translation | TAS | 9878253 | |
| Cellular component | GO term | Evidence | Neuro keywords | PubMed ID |
| GO:0005739 | mitochondrion | TAS | 9878253 |