Gene Page: ZSCAN23
Summary ?
| GeneID | 222696 |
| Symbol | ZSCAN23 |
| Synonyms | ZNF390|ZNF453|dJ29K1.3|dJ29K1.3.1 |
| Description | zinc finger and SCAN domain containing 23 |
| Reference | HGNC:HGNC:21193|Ensembl:ENSG00000187987|Vega:OTTHUMG00000016346 |
| Gene type | protein-coding |
| Map location | 6p22.1 |
| Pascal p-value | 1E-12 |
| Fetal beta | 0.933 |
| eGene | Caudate basal ganglia Cerebellar Hemisphere Cerebellum Cortex Hippocampus Hypothalamus Putamen basal ganglia |
Gene in Data Sources
| Gene set name | Method of gene set | Description | Info |
|---|---|---|---|
| CV:GWASdb | Genome-wide Association Studies | GWASdb records for schizophrenia | |
| CV:PGCnp | Genome-wide Association Study | GWAS |
Section I. Genetics and epigenetics annotation
eQTL annotation
| SNP ID | Chromosome | Position | eGene | Gene Entrez ID | pvalue | qvalue | TSS distance | eQTL type |
|---|---|---|---|---|---|---|---|---|
| rs1150691 | 6 | 28168033 | ZSCAN23 | ENSG00000187987.5 | 9.20779E-7 | 0.02 | 243246 | gtex_brain_putamen_basal |
| rs201833612 | 6 | 28381225 | ZSCAN23 | ENSG00000187987.5 | 5.14065E-6 | 0.02 | 30054 | gtex_brain_putamen_basal |
Section II. Transcriptome annotation
General gene expression (GTEx)
Gene expression during devlopment (BrainCloud)
Footnote:
A total of 269 time points ploted, with n=38 fetal samples (x=1:38). Each triangle represents one time point.
Gene expression of temporal and spatial changes (BrainSpan)
Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes the lower 25% and upper 25% of the expression distribution.
No co-expressed genes in brain regions
Section III. Gene Ontology annotation
| Molecular function | GO term | Evidence | Neuro keywords | PubMed ID |
|---|---|---|---|---|
| GO:0003700 | transcription factor activity | IEA | - | |
| GO:0008270 | zinc ion binding | IEA | - | |
| GO:0046872 | metal ion binding | IEA | - | |
| Biological process | GO term | Evidence | Neuro keywords | PubMed ID |
| GO:0006355 | regulation of transcription, DNA-dependent | IEA | - | |
| GO:0006350 | transcription | IEA | - | |
| Cellular component | GO term | Evidence | Neuro keywords | PubMed ID |
| GO:0005622 | intracellular | IEA | - | |
| GO:0005634 | nucleus | IEA | - |