| 1 | Int J Psychophysiol 2004 Apr 52: 147-57 |
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| PMID | 15050373 |
| Title | Correlation between P50 suppression and psychometric schizotypy among non-clinical Japanese subjects. |
| Abstract | The link between P50 suppression and psychometric schizotypy was previously reported in non-clinical English-speaking subjects; however, whether a similar relationship exists within a different ethnic sample is unknown. Furthermore, whether such a relationship can also be accounted for by such basic personality characteristics as extraversion or neuroticism has not yet been reported. In the present study, we investigated the correlations of P50 suppression with psychometric schizotypy, and with extraversion or neuroticism among non-clinical Japanese. Subjects were 34 healthy volunteers. The auditory P50 potential was obtained using a paired stimulus paradigm. Psychometric schizotypy was assessed using schizotypal personality questionnaire (SPQ). Extraversion and neuroticism were assessed using Maudsley personality inventory (MPI). P50 suppression correlated not only with total SPQ score, but also with extraversion and with neuroticism. However, the partial correlation analysis revealed a significant partial correlation of P50 suppression with SPQ when controlled for extraversion or neuroticism, and a non-significant partial correlation of P50 suppression with extraversion or neuroticism when controlled for SPQ. When subjects were divided into two subgroups according to the mean SPQ score, the degree of P50 suppression was lower in the high than in the low SPQ scorers. Our results indicate that P50 suppression is one of the neurobiological substrates underlying psychometric schizotypy, and that this relationship cannot be accounted for by measures of extraversion or neuroticism. |
| SCZ Keywords | schizophrenia, schizotypy, schizotypal |
| 2 | Int J Psychophysiol 2004 Apr 52: 147-57 |
|---|
| PMID | 15050373 |
| Title | Correlation between P50 suppression and psychometric schizotypy among non-clinical Japanese subjects. |
| Abstract | The link between P50 suppression and psychometric schizotypy was previously reported in non-clinical English-speaking subjects; however, whether a similar relationship exists within a different ethnic sample is unknown. Furthermore, whether such a relationship can also be accounted for by such basic personality characteristics as extraversion or neuroticism has not yet been reported. In the present study, we investigated the correlations of P50 suppression with psychometric schizotypy, and with extraversion or neuroticism among non-clinical Japanese. Subjects were 34 healthy volunteers. The auditory P50 potential was obtained using a paired stimulus paradigm. Psychometric schizotypy was assessed using schizotypal personality questionnaire (SPQ). Extraversion and neuroticism were assessed using Maudsley personality inventory (MPI). P50 suppression correlated not only with total SPQ score, but also with extraversion and with neuroticism. However, the partial correlation analysis revealed a significant partial correlation of P50 suppression with SPQ when controlled for extraversion or neuroticism, and a non-significant partial correlation of P50 suppression with extraversion or neuroticism when controlled for SPQ. When subjects were divided into two subgroups according to the mean SPQ score, the degree of P50 suppression was lower in the high than in the low SPQ scorers. Our results indicate that P50 suppression is one of the neurobiological substrates underlying psychometric schizotypy, and that this relationship cannot be accounted for by measures of extraversion or neuroticism. |
| SCZ Keywords | schizophrenia, schizotypy, schizotypal |
| 3 | J. Korean Med. Sci. 2015 Jun 30: 793-801 |
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| PMID | 26028934 |
| Title | A U-shaped Association between Body Mass Index and Psychological Distress on the Multiphasic Personality Inventory: Retrospective Cross-sectional Analysis of 19-year-old Men in Korea. |
| Abstract | Objective personality tests, such as the Minnesota Multiphasic Personality Inventory (MMPI), might be more sensitive to reflect subclinical personality and be more state-dependent in an individual's lifetime, so they are good scales to predict the psychological distress regarding certain states. The aim of this study was to identify the specific pattern between body mass index (BMI) and psychological distress using the objective personality test. For this study, we investigated BMI and the Korean Military Multiphasic Personality Inventory (MPI). A retrospective cross-sectional study was conducted with 19-yr-old examinees who were admitted to the Military Manpower Administration in Korea from February 2007 to January 2010. Of 1,088,107 examinees, we enrolled 771,408 subjects who were psychologically apparent healthy possible-military-service groups. Afterwards, we reviewed and analyzed directly measured BMI and MPI results. In terms of the validity scales, the faking-good subscale showed an inverted U-shaped association, and faking-bad and infrequency subscales showed a U-shaped association with BMI groups. In terms of the neurosis scales, all clinical subscales (anxiety, depression, somatization, and personality disorder) also showed a U-shaped association with BMI groups. For the psychopath scales, the schizophrenia subscale showed a U-shaped association, and the paranoia subscale showed a near-positive correlation with BMI. In conclusion, a specific U-shaped pattern was observed between BMI and the MPI in 19-yr-old men in Korea. Underweight and obesity are related to psychological distress, so supportive advice and education are needed to them. |
| SCZ Keywords | schizophrenia, schizotypy, schizotypal |