AMH | MIF | MIS | anti-Mullerian hormone | - | HPRD | 8596488 |
AR | AIS | DHTR | HUMARA | KD | NR3C4 | SBMA | SMAX1 | TFM | androgen receptor | Affinity Capture-Western Co-localization | BioGRID | 15288768 |15305378
|
AREG | AR | CRDGF | MGC13647 | SDGF | amphiregulin | - | HPRD,BioGRID | 10085134 |
ARF4 | ARF2 | ADP-ribosylation factor 4 | - | HPRD,BioGRID | 12446727 |
ATP5C1 | ATP5C | ATP5CL1 | ATP synthase, H+ transporting, mitochondrial F1 complex, gamma polypeptide 1 | Two-hybrid | BioGRID | 16169070 |
BTC | - | betacellulin | - | HPRD | 9528863 |
CALM1 | CALML2 | CAMI | DD132 | PHKD | calmodulin 1 (phosphorylase kinase, delta) | EGFR interacts with calmodulin | BIND | 14960328 |
CAMLG | CAML | MGC163197 | calcium modulating ligand | - | HPRD,BioGRID | 12919676 |
CASP1 | ICE | IL1BC | P45 | caspase 1, apoptosis-related cysteine peptidase (interleukin 1, beta, convertase) | - | HPRD,BioGRID | 11226410 |
CAV1 | CAV | MSTP085 | VIP21 | caveolin 1, caveolae protein, 22kDa | - | HPRD,BioGRID | 9374534 |
CAV3 | LGMD1C | LQT9 | MGC126100 | MGC126101 | MGC126129 | VIP-21 | VIP21 | caveolin 3 | - | HPRD,BioGRID | 9374534 |
CBL | C-CBL | CBL2 | RNF55 | Cas-Br-M (murine) ecotropic retroviral transforming sequence | Affinity Capture-Western | BioGRID | 10086340 |12061819
|
- | HPRD | 8662998 |
An unspecified isoform of EGFR interacts with CBL. | BIND | 15735736 |
c-Cbl ubiquitinates an unspecified isoform of EGFR. This interaction was modeled on a demonstrated interaction between c-Cbl and EGFR, both from an unspecified species. | BIND | 12234920 |
CBLB | DKFZp686J10223 | DKFZp779A0729 | DKFZp779F1443 | FLJ36865 | FLJ41152 | Nbla00127 | RNF56 | Cas-Br-M (murine) ecotropic retroviral transforming sequence b | - | HPRD,BioGRID | 10086340 |
CBLC | CBL-3 | CBL-SL | RNF57 | Cas-Br-M (murine) ecotropic retroviral transforming sequence c | - | HPRD,BioGRID | 10362357 |
CCND1 | BCL1 | D11S287E | PRAD1 | U21B31 | cyclin D1 | An unspecified isoform of EGFR binds to Cyclin D1 promoter. | BIND | 15950906 |
CD44 | CDW44 | CSPG8 | ECMR-III | HCELL | IN | LHR | MC56 | MDU2 | MDU3 | MGC10468 | MIC4 | MUTCH-I | Pgp1 | CD44 molecule (Indian blood group) | CD44 interacts with EGFR. | BIND | 12093135 |
- | HPRD,BioGRID | 12093135 |
CD82 | 4F9 | C33 | GR15 | IA4 | KAI1 | R2 | SAR2 | ST6 | TSPAN27 | CD82 molecule | - | HPRD,BioGRID | 10985391 |
CDC25A | CDC25A2 | cell division cycle 25 homolog A (S. pombe) | - | HPRD,BioGRID | 11912208 |
CDH1 | Arc-1 | CD324 | CDHE | ECAD | LCAM | UVO | cadherin 1, type 1, E-cadherin (epithelial) | EGFR interacts with E-cadherin | BIND | 14681060 |
- | HPRD,BioGRID | 10969083 |
CEBPB | C/EBP-beta | CRP2 | IL6DBP | LAP | MGC32080 | NF-IL6 | TCF5 | CCAAT/enhancer binding protein (C/EBP), beta | - | HPRD,BioGRID | 12095417 |
CRK | CRKII | v-crk sarcoma virus CT10 oncogene homolog (avian) | - | HPRD,BioGRID | 9642287 |
CSK | MGC117393 | c-src tyrosine kinase | Affinity Capture-MS | BioGRID | 16729043 |
CTNNB1 | CTNNB | DKFZp686D02253 | FLJ25606 | FLJ37923 | catenin (cadherin-associated protein), beta 1, 88kDa | - | HPRD,BioGRID | 9233779 |
CTNND1 | CAS | CTNND | KIAA0384 | P120CAS | P120CTN | p120 | catenin (cadherin-associated protein), delta 1 | Reconstituted Complex | BioGRID | 9535896 |
DCN | CSCD | DSPG2 | PG40 | PGII | PGS2 | SLRR1B | decorin | - | HPRD,BioGRID | 9988678 |12105206
|
DEGS1 | DEGS | DES1 | Des-1 | FADS7 | MGC5079 | MIG15 | MLD | degenerative spermatocyte homolog 1, lipid desaturase (Drosophila) | - | HPRD | 9188692 |
DOK2 | p56DOK | p56dok-2 | docking protein 2, 56kDa | - | HPRD,BioGRID | 10508618 |
DUSP3 | VHR | dual specificity phosphatase 3 | Biochemical Activity | BioGRID | 1281549 |
EGF | HOMG4 | URG | epidermal growth factor (beta-urogastrone) | - | HPRD | 10788520 |12093292 |12620237|12093292 |
EGF interacts with EGFR. | BIND | 15837620 |
- | HPRD,BioGRID | 12093292 |
EGFR interacts with EGF. This interaction was modelled on a demonstrated interaction between EGFR from human and EGF from mouse. | BIND | 8413296 |
An unspecified isoform of EGFR interacts with EGF. | BIND | 15950906 |
EGFR | ERBB | ERBB1 | HER1 | PIG61 | mENA | epidermal growth factor receptor (erythroblastic leukemia viral (v-erb-b) oncogene homolog, avian) | EGFR interacts with EGFR. | BIND | 15284455 |
Affinity Capture-Western | BioGRID | 14576349 |
EPPK1 | EPIPL | EPIPL1 | epiplakin 1 | - | HPRD | 12577067 |
EPS15 | AF-1P | AF1P | MLLT5 | epidermal growth factor receptor pathway substrate 15 | - | HPRD,BioGRID | 9049247 |
EPS8 | - | epidermal growth factor receptor pathway substrate 8 | - | HPRD | 7532293 |12127568
|
ERBB2 | CD340 | HER-2 | HER-2/neu | HER2 | NEU | NGL | TKR1 | v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian) | - | HPRD | 11500850 |
EGFR interacts with ErbB2. | BIND | 15652750 |
ERBB3 | ErbB-3 | HER3 | LCCS2 | MDA-BF-1 | MGC88033 | c-erbB-3 | c-erbB3 | erbB3-S | p180-ErbB3 | p45-sErbB3 | p85-sErbB3 | v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian) | - | HPRD,BioGRID | 10527633 |
EREG | ER | epiregulin | - | HPRD,BioGRID | 9419975 |
ESR1 | DKFZp686N23123 | ER | ESR | ESRA | Era | NR3A1 | estrogen receptor 1 | - | HPRD,BioGRID | 11887937 |
FER | TYK3 | fer (fps/fes related) tyrosine kinase | - | HPRD,BioGRID | 7623846 |
FOS | AP-1 | C-FOS | v-fos FBJ murine osteosarcoma viral oncogene homolog | An unspecified isoform of EGFR binds to c-fos promoter. | BIND | 15950906 |
GAB1 | - | GRB2-associated binding protein 1 | - | HPRD,BioGRID | 11432805 |
GNAI2 | GIP | GNAI2B | H_LUCA15.1 | H_LUCA16.1 | guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2 | - | HPRD | 11286993 |
GRB10 | GRB-IR | Grb-10 | IRBP | KIAA0207 | MEG1 | RSS | growth factor receptor-bound protein 10 | Grb10 interacts with EGFR. | BIND | 9506989 |
- | HPRD,BioGRID | 9006901 |9506989
|
GRB14 | - | growth factor receptor-bound protein 14 | - | HPRD,BioGRID | 8647858 |
GRB2 | ASH | EGFRBP-GRB2 | Grb3-3 | MST084 | MSTP084 | growth factor receptor-bound protein 2 | GRB2 interacts with an unspecified isoform of EGFR. This interaction was modeled on a demonstrated interaction between human GRB2, and rat EGFR. | BIND | 15782189 |
- | HPRD | 1322798 |7527043
|
EGFR interacts with GRB2. | BIND | 8305738 |
Affinity Capture-MS Affinity Capture-Western Reconstituted Complex | BioGRID | 1322798 |7510700 |7527043 |8647858 |9050991 |10026169 |10085134 |11960376 |12577067 |16729043
|
GRB7 | - | growth factor receptor-bound protein 7 | - | HPRD | 9710451 |
HBEGF | DTR | DTS | DTSF | HEGFL | heparin-binding EGF-like growth factor | - | HPRD,BioGRID | 12725245 |
HSP90AA1 | FLJ31884 | HSP86 | HSP89A | HSP90A | HSP90N | HSPC1 | HSPCA | HSPCAL1 | HSPCAL4 | HSPN | Hsp89 | Hsp90 | LAP2 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | EGFR interacts with Hsp90. This interaction was modeled on a demonstrated interaction between EGFR from an unspecified species and human Hsp90. | BIND | 12471035 |
HTT | HD | IT15 | huntingtin | - | HPRD,BioGRID | 9079622 |
IGF1R | CD221 | IGFIR | JTK13 | MGC142170 | MGC142172 | MGC18216 | insulin-like growth factor 1 receptor | Affinity Capture-Western | BioGRID | 17047074 |
INPPL1 | SHIP2 | inositol polyphosphate phosphatase-like 1 | - | HPRD,BioGRID | 11349134 |
ITGA5 | CD49e | FNRA | VLA5A | integrin, alpha 5 (fibronectin receptor, alpha polypeptide) | - | HPRD | 10888683 |
JAK2 | JTK10 | Janus kinase 2 (a protein tyrosine kinase) | Affinity Capture-Western | BioGRID | 10358079 |
JUP | ARVD12 | CTNNG | DP3 | DPIII | PDGB | PKGB | junction plakoglobin | Reconstituted Complex | BioGRID | 9535896 |
KRT17 | K17 | PC | PC2 | PCHC1 | keratin 17 | - | HPRD | 12577067 |
KRT18 | CYK18 | K18 | keratin 18 | - | HPRD | 12577067 |
KRT7 | CK7 | K2C7 | K7 | MGC129731 | MGC3625 | SCL | keratin 7 | - | HPRD | 12577067 |
KRT8 | CARD2 | CK8 | CYK8 | K2C8 | K8 | KO | keratin 8 | - | HPRD | 12577067 |
LRSAM1 | FLJ31641 | RIFLE | TAL | leucine rich repeat and sterile alpha motif containing 1 | Affinity Capture-Western | BioGRID | 15256501 |
MAP3K14 | FTDCR1B | HS | HSNIK | NIK | mitogen-activated protein kinase kinase kinase 14 | - | HPRD,BioGRID | 11116146 |
MAP4K1 | HPK1 | mitogen-activated protein kinase kinase kinase kinase 1 | - | HPRD,BioGRID | 9346925 |
MAPK14 | CSBP1 | CSBP2 | CSPB1 | EXIP | Mxi2 | PRKM14 | PRKM15 | RK | SAPK2A | p38 | p38ALPHA | mitogen-activated protein kinase 14 | Biochemical Activity | BioGRID | 7535770 |
MUC1 | CD227 | EMA | H23AG | MAM6 | PEM | PEMT | PUM | mucin 1, cell surface associated | - | HPRD,BioGRID | 11278868 |11483589
|
MUC1 interacts with and is tyrosine-phosphorylated by EGFR. | BIND | 11483589 |
NCK1 | MGC12668 | NCK | NCKalpha | NCK adaptor protein 1 | - | HPRD,BioGRID | 9362449 |
NCK2 | GRB4 | NCKbeta | NCK adaptor protein 2 | Affinity Capture-Western Reconstituted Complex | BioGRID | 9737977 |10026169
|
- | HPRD | 1333047 |9737977
|
NRG1 | ARIA | GGF | GGF2 | HGL | HRG | HRG1 | HRGA | NDF | SMDF | neuregulin 1 | Affinity Capture-Western | BioGRID | 7730382 |
- | HPRD | 8702572 |
PAK1 | MGC130000 | MGC130001 | PAKalpha | p21 protein (Cdc42/Rac)-activated kinase 1 | Tyrosine-phosphorylated EGFR interacts with PAK1. | BIND | 12522133 |
PDGFRB | CD140B | JTK12 | PDGF-R-beta | PDGFR | PDGFR1 | platelet-derived growth factor receptor, beta polypeptide | - | HPRD,BioGRID | 9506992 |
PIK3C2B | C2-PI3K | DKFZp686G16234 | phosphoinositide-3-kinase, class 2, beta polypeptide | - | HPRD,BioGRID | 11533253 |
PIK3R1 | GRB1 | p85 | p85-ALPHA | phosphoinositide-3-kinase, regulatory subunit 1 (alpha) | - | HPRD | 8662998 |
EGFR interacts with p85. This interaction was modeled on a demonstrated interaction between human EGFR and bovine p85. | BIND | 1372092 |
PIK3R2 | P85B | p85 | p85-BETA | phosphoinositide-3-kinase, regulatory subunit 2 (beta) | Tyrosine phosphorlyated EGFR interacts with p85-beta. | BIND | 11172806 |
PITPNA | MGC99649 | PITPN | VIB1A | phosphatidylinositol transfer protein, alpha | - | HPRD,BioGRID | 7761838 |
PLCG1 | PLC-II | PLC1 | PLC148 | PLCgamma1 | phospholipase C, gamma 1 | - | HPRD,BioGRID | 9207933 |
EGFR interacts with PLC-gamma. This interaction was modelled on a demonstrated interaction between human EGFR and bovine PLC-gamma. | BIND | 2173144 |2176151
|
PLD2 | - | phospholipase D2 | - | HPRD,BioGRID | 9837959 |
EGFR interacts with PLD1. This interaction was modelled on a demonstrated interaction between human EGFR and mouse PLD2. | BIND | 9837959 |
PLEC1 | EBS1 | EBSO | HD1 | PCN | PLEC1b | PLTN | plectin 1, intermediate filament binding protein 500kDa | - | HPRD | 12577067 |
PLSCR1 | MMTRA1B | phospholipid scramblase 1 | - | HPRD,BioGRID | 12009895 |
- | HPRD | 12009895 |12871937
|
PRKACA | MGC102831 | MGC48865 | PKACA | protein kinase, cAMP-dependent, catalytic, alpha | - | HPRD,BioGRID | 9050991 |
PRKAR1A | CAR | CNC | CNC1 | DKFZp779L0468 | MGC17251 | PKR1 | PPNAD1 | PRKAR1 | TSE1 | protein kinase, cAMP-dependent, regulatory, type I, alpha (tissue specific extinguisher 1) | - | HPRD,BioGRID | 9050991 |
PRKCA | AAG6 | MGC129900 | MGC129901 | PKC-alpha | PKCA | PRKACA | protein kinase C, alpha | - | HPRD,BioGRID | 12878187 |
PTK2 | FADK | FAK | FAK1 | pp125FAK | PTK2 protein tyrosine kinase 2 | - | HPRD,BioGRID | 10806474 |
PTK2B | CADTK | CAKB | FADK2 | FAK2 | FRNK | PKB | PTK | PYK2 | RAFTK | PTK2B protein tyrosine kinase 2 beta | - | HPRD,BioGRID | 10777553 |
PTK6 | BRK | FLJ42088 | PTK6 protein tyrosine kinase 6 | - | HPRD,BioGRID | 8940083 |
PTPN1 | PTP1B | protein tyrosine phosphatase, non-receptor type 1 | - | HPRD,BioGRID | 7540771 |8621392 |10889023 |12573287
|
PTPN11 | BPTP3 | CFC | MGC14433 | NS1 | PTP-1D | PTP2C | SH-PTP2 | SH-PTP3 | SHP2 | protein tyrosine phosphatase, non-receptor type 11 | - | HPRD,BioGRID | 7673163 |
PTPN6 | HCP | HCPH | HPTP1C | PTP-1C | SH-PTP1 | SHP-1 | SHP-1L | SHP1 | protein tyrosine phosphatase, non-receptor type 6 | - | HPRD,BioGRID | 9733788 |
PTPRJ | CD148 | DEP1 | HPTPeta | R-PTP-ETA | SCC1 | protein tyrosine phosphatase, receptor type, J | - | HPRD | 9115287 |
RASA1 | CM-AVM | CMAVM | DKFZp434N071 | GAP | PKWS | RASA | RASGAP | p120GAP | p120RASGAP | RAS p21 protein activator (GTPase activating protein) 1 | Reconstituted Complex | BioGRID | 8647858 |
GAP interacts with EGFR. | BIND | 1385407 |1850098 |2176151 |
- | HPRD | 1633149 |
RGS16 | A28-RGS14 | A28-RGS14P | RGS-R | regulator of G-protein signaling 16 | - | HPRD,BioGRID | 11602604 |
RIPK1 | FLJ39204 | RIP | RIP1 | receptor (TNFRSF)-interacting serine-threonine kinase 1 | - | HPRD,BioGRID | 11116146 |
ROS1 | MCF3 | ROS | c-ros-1 | c-ros oncogene 1 , receptor tyrosine kinase | Affinity Capture-Western | BioGRID | 11094073 |
SGSM2 | KIAA0397 | RUTBC1 | small G protein signaling modulator 2 | Two-hybrid | BioGRID | 16169070 |
SH2D3A | NSP1 | SH2 domain containing 3A | - | HPRD,BioGRID | 10187783 |
SH3BGRL | MGC117402 | SH3BGR | SH3 domain binding glutamic acid-rich protein like | Affinity Capture-MS | BioGRID | 16729043 |
SH3KBP1 | CIN85 | GIG10 | MIG18 | SH3-domain kinase binding protein 1 | Affinity Capture-Western | BioGRID | 11894095 |12177062
|
SHC1 | FLJ26504 | SHC | SHCA | SHC (Src homology 2 domain containing) transforming protein 1 | Shc interacts with activated EGFR. | BIND | 1623525 |
ShcA interacts with EGFR. | BIND | 8610109 |
ShcA interacts with the EGFR. | BIND | 8577769 |8610109 |8943228 |
- | HPRD,BioGRID | 9544989 |
EGF-R interacts with Shc. This interaction was modelled on a demonstrated interaction between human EGF-R and mouse Shc. | BIND | 8887653 |
SHC3 | N-Shc | NSHC | RAI | SHCC | SHC (Src homology 2 domain containing) transforming protein 3 | - | HPRD,BioGRID | 9507002 |
SNRPD2 | SMD2 | SNRPD1 | small nuclear ribonucleoprotein D2 polypeptide 16.5kDa | - | HPRD | 12577067 |
SNX1 | HsT17379 | MGC8664 | SNX1A | Vps5 | sorting nexin 1 | - | HPRD,BioGRID | 8638121 |9819414
|
SNX2 | MGC5204 | TRG-9 | sorting nexin 2 | - | HPRD,BioGRID | 9819414 |
SNX4 | - | sorting nexin 4 | - | HPRD,BioGRID | 9819414 |
SNX6 | MGC3157 | MSTP010 | TFAF2 | sorting nexin 6 | - | HPRD,BioGRID | 11279102 |
SOCS1 | CIS1 | CISH1 | JAB | SOCS-1 | SSI-1 | SSI1 | TIP3 | suppressor of cytokine signaling 1 | - | HPRD,BioGRID | 12070153 |
SOCS3 | ATOD4 | CIS3 | Cish3 | MGC71791 | SOCS-3 | SSI-3 | SSI3 | suppressor of cytokine signaling 3 | - | HPRD,BioGRID | 12070153 |
SOS1 | GF1 | GGF1 | GINGF | HGF | NS4 | son of sevenless homolog 1 (Drosophila) | - | HPRD,BioGRID | 9447973 |
SOS2 | FLJ25596 | son of sevenless homolog 2 (Drosophila) | - | HPRD,BioGRID | 10675333 |
SRC | ASV | SRC1 | c-SRC | p60-Src | v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian) | - | HPRD,BioGRID | 10971656 |
STAT1 | DKFZp686B04100 | ISGF-3 | STAT91 | signal transducer and activator of transcription 1, 91kDa | - | HPRD,BioGRID | 12070153 |
STAT3 | APRF | FLJ20882 | HIES | MGC16063 | signal transducer and activator of transcription 3 (acute-phase response factor) | Affinity Capture-Western | BioGRID | 10358079 |15485908
|
Tyrosine phophorylated EGFR interacts with STAT3. | BIND | 12873986 |
STAT5A | MGF | STAT5 | signal transducer and activator of transcription 5A | - | HPRD,BioGRID | 10358079 |
STAT5B | STAT5 | signal transducer and activator of transcription 5B | - | HPRD,BioGRID | 10558875 |
TGFA | TFGA | transforming growth factor, alpha | - | HPRD,BioGRID | 12297049 |
TJP1 | DKFZp686M05161 | MGC133289 | ZO-1 | tight junction protein 1 (zona occludens 1) | - | HPRD,BioGRID | 12708492 |
TNC | HXB | MGC167029 | TN | tenascin C | - | HPRD | 11470832 |
TNK2 | ACK | ACK1 | FLJ44758 | FLJ45547 | p21cdc42Hs | tyrosine kinase, non-receptor, 2 | - | HPRD | 8497321 |8647288
|
VAV1 | VAV | vav 1 guanine nucleotide exchange factor | - | HPRD,BioGRID | 10938113 |
VAV2 | - | vav 2 guanine nucleotide exchange factor | Tyrosine phosphorylated EGFR interacts with and phosphorylates Vav2. | BIND | 12454019 |
- | HPRD,BioGRID | 10618391 |10938113
|
VAV3 | FLJ40431 | vav 3 guanine nucleotide exchange factor | Affinity Capture-Western | BioGRID | 10938113 |
- | HPRD | 11094073 |
WAS | IMD2 | THC | WASP | Wiskott-Aldrich syndrome (eczema-thrombocytopenia) | Affinity Capture-Western | BioGRID | 9307968 |
XPO6 | EXP6 | FLJ22519 | KIAA0370 | RANBP20 | exportin 6 | - | HPRD | 14592989 |
XRCC6 | CTC75 | CTCBF | G22P1 | KU70 | ML8 | TLAA | X-ray repair complementing defective repair in Chinese hamster cells 6 | - | HPRD | 9430697 |
YWHAZ | KCIP-1 | MGC111427 | MGC126532 | MGC138156 | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide | EGFR interacts with 14-3-3-zeta. | BIND | 15225635 |
ZNF259 | MGC110983 | ZPR1 | zinc finger protein 259 | - | HPRD | 8650580 |10938113|10938113
|
- | HPRD | 10938113 |