Gene Page: FBP1

Summary
GeneID  2203
Symbol  FBP1
Synonyms  FBP
Description  fructose-1,6-bisphosphatase 1
See related  HGNC:3606|MIM:611570|Ensembl:ENSG00000165140|HPRD:01973|
Locus tag  -
Gene type  protein-coding
Map location  9q22.3
 
Gene in Data Sources
Gene set name Method of gene set Evidence Info
LiteratureHigh-throughput literature-searchCo-occurance with Schizophrenia keywords: [schizophrenias, schizophrenia]Click to show detail
 
General Gene Expression (microarray) ?
 
Gene Expression in Brain Regions (new)
 
Top co-expressed genes in Brain Regions (new)
GenePearson's Correlation Spearman's Correlation
Top 10 positively co-expressed genes
C9orf1020.890.91
C3orf630.890.90
C12orf300.890.90
MAP3K20.880.90
HLTF0.880.90
IBTK0.880.89
UBR10.870.91
GPR1070.870.90
YTHDC20.870.90
LYST0.870.90
Top 10 negatively co-expressed genes
AF347015.31-0.70-0.75
MT-CO2-0.69-0.75
AF347015.27-0.68-0.72
AF347015.8-0.68-0.74
FXYD1-0.67-0.71
AF347015.21-0.67-0.74
HIGD1B-0.67-0.73
AF347015.33-0.66-0.70
MT-CYB-0.66-0.71
IFI27-0.65-0.70
Gene Ontology
Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0004331fructose-2,6-bisphosphate 2-phosphatase activityTAS8387495 
GO:0016787hydrolase activityIEA-
GO:0008270zinc ion bindingIEA-
GO:0042578phosphoric ester hydrolase activityIEA-
GO:0042132fructose 1,6-bisphosphate 1-phosphatase activityEXP9382095 
GO:0042132fructose 1,6-bisphosphate 1-phosphatase activityIEA-
GO:0042802identical protein bindingIPI16169070 
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0006094gluconeogenesisIEA-
GO:0006000fructose metabolic processTAS7558035 
GO:0005975carbohydrate metabolic processIEA-
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0005829cytosolEXP9382095 
GO:0005739mitochondrionIDA18029348 
 
Protein-protein InteractionsShown by network
InteractorsAliases BOfficial full name BExperimentalSourcePubMed ID
ACTN1FLJ40884actinin, alpha 1-HPRD,BioGRID12507293 
ASCC2ASC1p100activating signal cointegrator 1 complex subunit 2Two-hybridBioGRID16169070 
ATP5J2ATP5JLATP synthase, H+ transporting, mitochondrial F0 complex, subunit F2Two-hybridBioGRID16169070 
C14orf135FBP2 | FLJ12799 | FLJ38170chromosome 14 open reading frame 135Two-hybridBioGRID16189514 
FBP1FBPfructose-1,6-bisphosphatase 1-HPRD,BioGRID2164670 
FXR2FMR1L2fragile X mental retardation, autosomal homolog 2Two-hybridBioGRID16189514 
HSPA8HSC54 | HSC70 | HSC71 | HSP71 | HSP73 | HSPA10 | LAP1 | MGC131511 | MGC29929 | NIP71heat shock 70kDa protein 8Two-hybridBioGRID16169070 
LNX1LNX | MPDZ | PDZRN2ligand of numb-protein X 1Two-hybridBioGRID16189514 
RNF183FLJ31197 | MGC4734ring finger protein 183Two-hybridBioGRID16189514 
 
Pathway annotation
Pathway namePathway size# SZGR genes in pathwayInfo
KEGG_GLYCOLYSIS_GLUCONEOGENESIS 6241All SZGR genes in this pathway
KEGG_PENTOSE_PHOSPHATE_PATHWAY 2714All SZGR genes in this pathway
KEGG_FRUCTOSE_AND_MANNOSE_METABOLISM 3423All SZGR genes in this pathway
KEGG_INSULIN_SIGNALING_PATHWAY 137103All SZGR genes in this pathway
REACTOME_GLUCONEOGENESIS 3421All SZGR genes in this pathway
REACTOME_METABOLISM_OF_CARBOHYDRATES 247154All SZGR genes in this pathway
REACTOME_GLUCOSE_METABOLISM 6942All SZGR genes in this pathway
LIU_PROSTATE_CANCER_UP 9657All SZGR genes in this pathway
CHARAFE_BREAST_CANCER_LUMINAL_VS_MESENCHYMAL_UP 450256All SZGR genes in this pathway
DOANE_BREAST_CANCER_ESR1_UP 11272All SZGR genes in this pathway
SMIRNOV_CIRCULATING_ENDOTHELIOCYTES_IN_CANCER_UP 158103All SZGR genes in this pathway
MULLIGHAN_MLL_SIGNATURE_2_UP 418263All SZGR genes in this pathway
GOZGIT_ESR1_TARGETS_DN 781465All SZGR genes in this pathway
LINDGREN_BLADDER_CANCER_CLUSTER_1_UP 12171All SZGR genes in this pathway
LINDGREN_BLADDER_CANCER_WITH_LOH_IN_CHR9Q 11671All SZGR genes in this pathway
FARMER_BREAST_CANCER_BASAL_VS_LULMINAL 330215All SZGR genes in this pathway
LUI_THYROID_CANCER_CLUSTER_2 4231All SZGR genes in this pathway
YANG_BREAST_CANCER_ESR1_UP 3622All SZGR genes in this pathway
HATADA_METHYLATED_IN_LUNG_CANCER_UP 390236All SZGR genes in this pathway
BENPORATH_SUZ12_TARGETS 1038678All SZGR genes in this pathway
BENPORATH_EED_TARGETS 1062725All SZGR genes in this pathway
BENPORATH_ES_WITH_H3K27ME3 1118744All SZGR genes in this pathway
BENPORATH_PRC2_TARGETS 652441All SZGR genes in this pathway
TARTE_PLASMA_CELL_VS_PLASMABLAST_UP 398262All SZGR genes in this pathway
MAGRANGEAS_MULTIPLE_MYELOMA_IGG_VS_IGA_DN 2616All SZGR genes in this pathway
ROSS_AML_WITH_MLL_FUSIONS 7845All SZGR genes in this pathway
VANTVEER_BREAST_CANCER_METASTASIS_UP 5631All SZGR genes in this pathway
FLECHNER_BIOPSY_KIDNEY_TRANSPLANT_REJECTED_VS_OK_DN 546351All SZGR genes in this pathway
NAKAJIMA_EOSINOPHIL 3020All SZGR genes in this pathway
HSIAO_LIVER_SPECIFIC_GENES 244154All SZGR genes in this pathway
LEI_MYB_TARGETS 318215All SZGR genes in this pathway
LENAOUR_DENDRITIC_CELL_MATURATION_DN 12890All SZGR genes in this pathway
ABBUD_LIF_SIGNALING_1_UP 4629All SZGR genes in this pathway
VERHAAK_AML_WITH_NPM1_MUTATED_UP 183111All SZGR genes in this pathway
ZHAN_V2_LATE_DIFFERENTIATION_GENES 4534All SZGR genes in this pathway
KUMAR_TARGETS_OF_MLL_AF9_FUSION 405264All SZGR genes in this pathway
WESTON_VEGFA_TARGETS_6HR 5938All SZGR genes in this pathway
BAELDE_DIABETIC_NEPHROPATHY_UP 8648All SZGR genes in this pathway
WESTON_VEGFA_TARGETS 10871All SZGR genes in this pathway
BROWNE_HCMV_INFECTION_12HR_UP 11168All SZGR genes in this pathway
BROWNE_HCMV_INFECTION_6HR_UP 7148All SZGR genes in this pathway
CREIGHTON_ENDOCRINE_THERAPY_RESISTANCE_5 482296All SZGR genes in this pathway
MARTINEZ_RB1_TARGETS_DN 543317All SZGR genes in this pathway
MARTINEZ_TP53_TARGETS_DN 593372All SZGR genes in this pathway
MARTINEZ_RB1_AND_TP53_TARGETS_DN 591366All SZGR genes in this pathway
ACEVEDO_LIVER_CANCER_DN 540340All SZGR genes in this pathway
ACEVEDO_LIVER_TUMOR_VS_NORMAL_ADJACENT_TISSUE_DN 274165All SZGR genes in this pathway
SMID_BREAST_CANCER_RELAPSE_IN_BONE_UP 9761All SZGR genes in this pathway
SMID_BREAST_CANCER_LUMINAL_B_UP 172109All SZGR genes in this pathway
SMID_BREAST_CANCER_BASAL_DN 701446All SZGR genes in this pathway
BOCHKIS_FOXA2_TARGETS 425261All SZGR genes in this pathway
MUELLER_PLURINET 299189All SZGR genes in this pathway
RUTELLA_RESPONSE_TO_CSF2RB_AND_IL4_DN 315201All SZGR genes in this pathway
RUTELLA_RESPONSE_TO_HGF_UP 418282All SZGR genes in this pathway
RUTELLA_RESPONSE_TO_HGF_VS_CSF2RB_AND_IL4_UP 408276All SZGR genes in this pathway
VANTVEER_BREAST_CANCER_ESR1_UP 16799All SZGR genes in this pathway
SHEDDEN_LUNG_CANCER_GOOD_SURVIVAL_A4 196124All SZGR genes in this pathway
CHIANG_LIVER_CANCER_SUBCLASS_CTNNB1_DN 170105All SZGR genes in this pathway
CAIRO_HEPATOBLASTOMA_DN 267160All SZGR genes in this pathway
MIKKELSEN_MEF_HCP_WITH_H3K27ME3 590403All SZGR genes in this pathway
MOOTHA_GLUCONEOGENESIS 3223All SZGR genes in this pathway
MOOTHA_GLYCOLYSIS 2113All SZGR genes in this pathway
ZEMBUTSU_SENSITIVITY_TO_CISPLATIN 2014All SZGR genes in this pathway
LI_INDUCED_T_TO_NATURAL_KILLER_DN 11683All SZGR genes in this pathway
MARTENS_TRETINOIN_RESPONSE_UP 857456All SZGR genes in this pathway
CHYLA_CBFA2T3_TARGETS_UP 387225All SZGR genes in this pathway
FEVR_CTNNB1_TARGETS_DN 553343All SZGR genes in this pathway
SERVITJA_ISLET_HNF1A_TARGETS_DN 10971All SZGR genes in this pathway
PEDERSEN_METASTASIS_BY_ERBB2_ISOFORM_7 403240All SZGR genes in this pathway
RATTENBACHER_BOUND_BY_CELF1 467251All SZGR genes in this pathway
ACEVEDO_FGFR1_TARGETS_IN_PROSTATE_CANCER_MODEL_UP 289184All SZGR genes in this pathway


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