Gene Page: INHBB

Summary
GeneID  3625
Symbol  INHBB
Synonyms  MGC157939
Description  inhibin, beta B
See related  HGNC:6067|MIM:147390|Ensembl:ENSG00000163083|HPRD:00934|
Locus tag  -
Gene type  protein-coding
Map location  2cen-q13
 
Gene in Data Sources
Gene set name Method of gene set Evidence Info
GSMA_Igenome scan meta-analysisPsr: 0.023 
GSMA_IIAgenome scan meta-analysis (All samples)Psr: 0.00755 
 
General Gene Expression (microarray) ?
 
Gene Expression in Brain Regions (new)
 
Top co-expressed genes in Brain Regions (new)
GenePearson's Correlation Spearman's Correlation
Top 10 positively co-expressed genes
Top 10 negatively co-expressed genes
Gene Ontology
Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0005179hormone activityTAS3122219 
GO:0005125cytokine activityTAS3122219 
GO:0008083growth factor activityIEA-
GO:0042803protein homodimerization activityIPI2575216 
GO:0046789host cell surface receptor bindingTAS12456957 
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0001541ovarian follicle developmentNAS12790766 
GO:0009605response to external stimulusIDA10320815 
GO:0006952defense responseTAS3122219 
GO:0030154cell differentiationNAS10320815 
GO:0040007growthIEA-
GO:0048178negative regulation of hepatocyte growth factor biosynthetic processIDA12419948 
GO:0046881positive regulation of follicle-stimulating hormone secretionIPI3122219 
GO:0046882negative regulation of follicle-stimulating hormone secretionIPI3122219 
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0005576extracellular regionTAS3122219 
 
Protein-protein InteractionsShown by network
InteractorsAliases BOfficial full name BExperimentalSourcePubMed ID
ACVR1ACTRI | ACVR1A | ACVRLK2 | ALK2 | FOP | SKR1 | TSRIactivin A receptor, type I-HPRD11266516 
ACVR1BACTRIB | ACVRLK4 | ALK4 | SKR2activin A receptor, type IB-HPRD11266516 |12032389 
|15196700 
Affinity Capture-WesternBioGRID9202237 
ACVR1CACVRLK7 | ALK7activin A receptor, type IC-HPRD15196700 
ACVR2AACTRII | ACVR2activin A receptor, type IIAAffinity Capture-WesternBioGRID9202237 
-HPRD11266516 
ACVR2BACTRIIB | ActR-IIB | MGC116908activin A receptor, type IIB-HPRD,BioGRID9202237 
IGSF1IGCD1 | IGDC1 | INHBP | KIAA0364 | MGC75490 | PGSF2immunoglobulin superfamily, member 1-HPRD11266516 
INHA-inhibin, alpha-HPRD11134153 
INHBAEDF | FRPinhibin, beta A-HPRD11134153 
INHBCIHBCinhibin, beta C-HPRD11134153 
 
Pathway annotation
Pathway namePathway size# SZGR genes in pathwayInfo
KEGG_CYTOKINE_CYTOKINE_RECEPTOR_INTERACTION 267161All SZGR genes in this pathway
KEGG_TGF_BETA_SIGNALING_PATHWAY 8664All SZGR genes in this pathway
REACTOME_METABOLISM_OF_AMINO_ACIDS_AND_DERIVATIVES 200136All SZGR genes in this pathway
REACTOME_GLYCOPROTEIN_HORMONES 128All SZGR genes in this pathway
REACTOME_PEPTIDE_HORMONE_BIOSYNTHESIS 1410All SZGR genes in this pathway
THUM_SYSTOLIC_HEART_FAILURE_UP 423283All SZGR genes in this pathway
CHARAFE_BREAST_CANCER_LUMINAL_VS_BASAL_UP 380215All SZGR genes in this pathway
CHARAFE_BREAST_CANCER_LUMINAL_VS_MESENCHYMAL_UP 450256All SZGR genes in this pathway
ZHOU_INFLAMMATORY_RESPONSE_FIMA_DN 284156All SZGR genes in this pathway
DODD_NASOPHARYNGEAL_CARCINOMA_UP 1821933All SZGR genes in this pathway
DELYS_THYROID_CANCER_UP 443294All SZGR genes in this pathway
GRAESSMANN_APOPTOSIS_BY_SERUM_DEPRIVATION_UP 552347All SZGR genes in this pathway
GRAESSMANN_RESPONSE_TO_MC_AND_SERUM_DEPRIVATION_UP 211136All SZGR genes in this pathway
GRAESSMANN_APOPTOSIS_BY_DOXORUBICIN_UP 1142669All SZGR genes in this pathway
MCBRYAN_PUBERTAL_BREAST_3_4WK_UP 214144All SZGR genes in this pathway
MCBRYAN_PUBERTAL_BREAST_4_5WK_UP 271175All SZGR genes in this pathway
STREICHER_LSM1_TARGETS_UP 4434All SZGR genes in this pathway
PEREZ_TP63_TARGETS 355243All SZGR genes in this pathway
SANCHEZ_MDM2_TARGETS 1510All SZGR genes in this pathway
DACOSTA_UV_RESPONSE_VIA_ERCC3_DN 855609All SZGR genes in this pathway
HOWLIN_PUBERTAL_MAMMARY_GLAND 6940All SZGR genes in this pathway
NUYTTEN_NIPP1_TARGETS_DN 848527All SZGR genes in this pathway
NUYTTEN_EZH2_TARGETS_DN 1024594All SZGR genes in this pathway
MANTOVANI_NFKB_TARGETS_UP 4333All SZGR genes in this pathway
MANTOVANI_VIRAL_GPCR_SIGNALING_UP 8654All SZGR genes in this pathway
BUYTAERT_PHOTODYNAMIC_THERAPY_STRESS_DN 637377All SZGR genes in this pathway
GOTZMANN_EPITHELIAL_TO_MESENCHYMAL_TRANSITION_UP 6955All SZGR genes in this pathway
BENPORATH_EED_TARGETS 1062725All SZGR genes in this pathway
SWEET_KRAS_TARGETS_DN 6639All SZGR genes in this pathway
FRASOR_RESPONSE_TO_ESTRADIOL_DN 8252All SZGR genes in this pathway
HALMOS_CEBPA_TARGETS_DN 4626All SZGR genes in this pathway
MARTINEZ_RESPONSE_TO_TRABECTEDIN_UP 7149All SZGR genes in this pathway
LU_AGING_BRAIN_UP 262186All SZGR genes in this pathway
WANG_SMARCE1_TARGETS_UP 280183All SZGR genes in this pathway
BILD_E2F3_ONCOGENIC_SIGNATURE 246153All SZGR genes in this pathway
CREIGHTON_ENDOCRINE_THERAPY_RESISTANCE_5 482296All SZGR genes in this pathway
MASSARWEH_TAMOXIFEN_RESISTANCE_UP 578341All SZGR genes in this pathway
WALLACE_PROSTATE_CANCER_RACE_DN 8842All SZGR genes in this pathway
MCGARVEY_SILENCED_BY_METHYLATION_IN_COLON_CANCER 4229All SZGR genes in this pathway
MATZUK_POST-IMPLANTATION_AND_POST-PARTUM 1413All SZGR genes in this pathway
QI_PLASMACYTOMA_DN 10063All SZGR genes in this pathway
HUPER_BREAST_BASAL_VS_LUMINAL_DN 5944All SZGR genes in this pathway
GU_PDEF_TARGETS_DN 3920All SZGR genes in this pathway
YOSHIMURA_MAPK8_TARGETS_UP 1305895All SZGR genes in this pathway
SWEET_LUNG_CANCER_KRAS_UP 491316All SZGR genes in this pathway
LI_WILMS_TUMOR 2712All SZGR genes in this pathway
ZHANG_TLX_TARGETS_60HR_UP 293203All SZGR genes in this pathway
MEISSNER_BRAIN_HCP_WITH_H3K4ME3_AND_H3K27ME3 1069729All SZGR genes in this pathway
BOYAULT_LIVER_CANCER_SUBCLASS_G2 2717All SZGR genes in this pathway
CAIRO_HEPATOBLASTOMA_DN 267160All SZGR genes in this pathway
WONG_ADULT_TISSUE_STEM_MODULE 721492All SZGR genes in this pathway
MARTENS_TRETINOIN_RESPONSE_UP 857456All SZGR genes in this pathway
PANGAS_TUMOR_SUPPRESSION_BY_SMAD1_AND_SMAD5_DN 157106All SZGR genes in this pathway
BRUINS_UVC_RESPONSE_VIA_TP53_GROUP_A 898516All SZGR genes in this pathway
LEE_BMP2_TARGETS_UP 745475All SZGR genes in this pathway
WACKER_HYPOXIA_TARGETS_OF_VHL 1311All SZGR genes in this pathway
KATSANOU_ELAVL1_TARGETS_DN 14888All SZGR genes in this pathway
WANG_THOC1_TARGETS_DN 2014All SZGR genes in this pathway
FORTSCHEGGER_PHF8_TARGETS_DN 784464All SZGR genes in this pathway
NABA_SECRETED_FACTORS 344197All SZGR genes in this pathway
NABA_MATRISOME_ASSOCIATED 753411All SZGR genes in this pathway
NABA_MATRISOME 1028559All SZGR genes in this pathway
miRNA Targets ?
miRNA familyTarget positionmiRNA IDmiRNA seq
UTR startUTR endMatch method
miR-130/30114581464m8hsa-miR-130abrainCAGUGCAAUGUUAAAAGGGCAU
hsa-miR-301CAGUGCAAUAGUAUUGUCAAAGC
hsa-miR-130bbrainCAGUGCAAUGAUGAAAGGGCAU
hsa-miR-454-3pUAGUGCAAUAUUGCUUAUAGGGUUU
miR-1382832891Ahsa-miR-138brainAGCUGGUGUUGUGAAUC
hsa-miR-138brainAGCUGGUGUUGUGAAUC
miR-14513701376m8hsa-miR-145GUCCAGUUUUCCCAGGAAUCCCUU
miR-148/152145914661A,m8hsa-miR-148aUCAGUGCACUACAGAACUUUGU
hsa-miR-152brainUCAGUGCAUGACAGAACUUGGG
hsa-miR-148bUCAGUGCAUCACAGAACUUUGU
miR-1492422481Ahsa-miR-149brainUCUGGCUCCGUGUCUUCACUCC
miR-153133513421A,m8hsa-miR-153UUGCAUAGUCACAAAAGUGA
miR-1914571463m8hsa-miR-19aUGUGCAAAUCUAUGCAAAACUGA
hsa-miR-19bUGUGCAAAUCCAUGCAAAACUGA
miR-2184164231A,m8hsa-miR-218brainUUGUGCUUGAUCUAACCAUGU
miR-26140414111A,m8hsa-miR-26abrainUUCAAGUAAUCCAGGAUAGGC
hsa-miR-26bSZUUCAAGUAAUUCAGGAUAGGUU
miR-34/449149014961Ahsa-miR-34abrainUGGCAGUGUCUUAGCUGGUUGUU
hsa-miR-34cAGGCAGUGUAGUUAGCUGAUUGC
hsa-miR-449UGGCAGUGUAUUGUUAGCUGGU
hsa-miR-449bAGGCAGUGUAUUGUUAGCUGGC
miR-448133613421Ahsa-miR-448UUGCAUAUGUAGGAUGUCCCAU
miR-54411201126m8hsa-miR-544AUUCUGCAUUUUUAGCAAGU
miR-93.hd/291-3p/294/295/302/372/373/52012471253m8hsa-miR-93brainAAAGUGCUGUUCGUGCAGGUAG
hsa-miR-302aUAAGUGCUUCCAUGUUUUGGUGA
hsa-miR-302bUAAGUGCUUCCAUGUUUUAGUAG
hsa-miR-302cUAAGUGCUUCCAUGUUUCAGUGG
hsa-miR-302dUAAGUGCUUCCAUGUUUGAGUGU
hsa-miR-372AAAGUGCUGCGACAUUUGAGCGU
hsa-miR-373GAAGUGCUUCGAUUUUGGGGUGU
hsa-miR-520eAAAGUGCUUCCUUUUUGAGGG
hsa-miR-520aAAAGUGCUUCCCUUUGGACUGU
hsa-miR-520bAAAGUGCUUCCUUUUAGAGGG
hsa-miR-520cAAAGUGCUUCCUUUUAGAGGGUU
hsa-miR-520dAAAGUGCUUCUCUUUGGUGGGUU
  • SZ: miRNAs which differentially expressed in brain cortex of schizophrenia patients comparing with control samples using microarray. Click here to see the list of SZ related miRNAs.
  • Brain: miRNAs which are expressed in brain based on miRNA microarray expression studies. Click here to see the list of brain related miRNAs.


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